3TQJ
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![BU of 3tqj by Molmil](/molmil-images/mine/3tqj) | Structure of the superoxide dismutase (Fe) (sodB) from Coxiella burnetii | Descriptor: | FE (II) ION, Superoxide dismutase [Fe] | Authors: | Franklin, M.C, Cheung, J, Cassidy, M, Love, J. | Deposit date: | 2011-09-09 | Release date: | 2011-09-21 | Last modified: | 2023-09-13 | Method: | X-RAY DIFFRACTION (2.004 Å) | Cite: | Structural genomics for drug design against the pathogen Coxiella burnetii. Proteins, 83, 2015
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3TRK
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![BU of 3trk by Molmil](/molmil-images/mine/3trk) | Structure of the Chikungunya virus nsP2 protease | Descriptor: | Nonstructural polyprotein, SODIUM ION | Authors: | Cheung, J, Franklin, M, Mancia, F, Rudolph, M, Cassidy, M, Gary, E, Burshteyn, F, Love, J. | Deposit date: | 2011-09-09 | Release date: | 2011-09-28 | Last modified: | 2023-12-06 | Method: | X-RAY DIFFRACTION (2.397 Å) | Cite: | Structure of the Chikungunya virus nsP2 protease To be Published
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4CXR
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![BU of 4cxr by Molmil](/molmil-images/mine/4cxr) | Mycobaterium tuberculosis transaminase BioA complexed with 1-(1,3- benzothiazol-2-yl)methanamine | Descriptor: | 1,2-ETHANEDIOL, 1-(1,3-benzothiazol-2-yl)methanamine, ADENOSYLMETHIONINE-8-AMINO-7-OXONONANOATE AMINOTRANSFERASE, ... | Authors: | Dai, R, Geders, T.W, Finzel, B.C. | Deposit date: | 2014-04-08 | Release date: | 2014-04-23 | Last modified: | 2023-12-20 | Method: | X-RAY DIFFRACTION (1.7 Å) | Cite: | Inhibition of Mycobacterium Tuberculosis Transaminase Bioa by Aryl Hydrazines and Hydrazides. Chembiochem, 15, 2014
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2OTH
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![BU of 2oth by Molmil](/molmil-images/mine/2oth) | Crystal structure of a ternary complex of phospholipase A2 with indomethacin and nimesulide at 2.9 A resolution | Descriptor: | 4-NITRO-2-PHENOXYMETHANESULFONANILIDE, ACETONITRILE, INDOMETHACIN, ... | Authors: | Kumar, S, Singh, N, Sharma, S, Kaur, P, Singh, T.P. | Deposit date: | 2007-02-08 | Release date: | 2007-02-27 | Last modified: | 2023-10-25 | Method: | X-RAY DIFFRACTION (2.9 Å) | Cite: | Crystal structure of a ternary complex of phospholipase A2 with indomethacin and nimesulide at 2.9 A resolution To be Published
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4CA6
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![BU of 4ca6 by Molmil](/molmil-images/mine/4ca6) | Human Angiotensin converting enzyme N-domain in complex with a phosphinic tripeptide FI | Descriptor: | 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, ANGIOTENSIN-CONVERTING ENZYME N-DOMAIN, CHLORIDE ION, ... | Authors: | Masuyer, G, Akif, M, Czarny, B, Beau, F, Schwager, S.L.U, Sturrock, E.D, Isaac, R.E, Dive, V, Acharya, K.R. | Deposit date: | 2013-10-07 | Release date: | 2013-12-11 | Last modified: | 2023-12-20 | Method: | X-RAY DIFFRACTION (1.91 Å) | Cite: | Crystal structures of highly specific phosphinic tripeptide enantiomers in complex with the angiotensin-I converting enzyme. FEBS J., 281, 2014
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4BXK
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![BU of 4bxk by Molmil](/molmil-images/mine/4bxk) | Crystal structure of the Angiotensin-1 converting enzyme N-domain in complex with a domain-specific inhibitor | Descriptor: | 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, ANGIOTENSIN-CONVERTING ENZYME, ... | Authors: | Douglas, R.G, Sharma, R.K, Masuyer, G, Lubbe, L, Zamora, I, Acharya, K.R, Chibale, K, Sturrock, E.D. | Deposit date: | 2013-07-12 | Release date: | 2013-09-18 | Last modified: | 2023-12-20 | Method: | X-RAY DIFFRACTION (2.2 Å) | Cite: | Fragment-Based Design for the Development of N-Domain Selective Angiotensin-1 Converting Enzyme Inhibitors Clin.Sci., 126, 2014
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4CA7
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![BU of 4ca7 by Molmil](/molmil-images/mine/4ca7) | Drosophila Angiotensin converting enzyme (AnCE) in complex with a phosphinic tripeptide FI | Descriptor: | 2-acetamido-2-deoxy-beta-D-glucopyranose, ANGIOTENSIN-CONVERTING ENZYME, N-{(2S)-3-[(S)-[(1R)-1-{[(benzyloxy)carbonyl]amino}-2-phenylethyl](hydroxy)phosphoryl]-2-[(3-phenyl-1,2-oxazol-5-yl)methyl]propanoyl}-L-tyrosine, ... | Authors: | Masuyer, G, Akif, M, Czarny, B, Beau, F, Schwager, S.L.U, Sturrock, E.D, Isaac, R.E, Dive, V, Acharya, K.R. | Deposit date: | 2013-10-07 | Release date: | 2013-12-11 | Last modified: | 2023-12-20 | Method: | X-RAY DIFFRACTION (1.82 Å) | Cite: | Crystal Structures of Highly Specific Phosphinic Tripeptide Enantiomers in Complex with the Angiotensin-I Converting Enzyme. FEBS J., 281, 2014
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256B
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![BU of 256b by Molmil](/molmil-images/mine/256b) | |
3TQ9
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![BU of 3tq9 by Molmil](/molmil-images/mine/3tq9) | Structure of the dihydrofolate reductase (folA) from Coxiella burnetii in complex with methotrexate | Descriptor: | Dihydrofolate reductase, METHOTREXATE, NADPH DIHYDRO-NICOTINAMIDE-ADENINE-DINUCLEOTIDE PHOSPHATE | Authors: | Franklin, M.C, Cassidy, M, Hillerich, B, Love, J. | Deposit date: | 2011-09-09 | Release date: | 2011-11-02 | Last modified: | 2024-04-03 | Method: | X-RAY DIFFRACTION (2.3 Å) | Cite: | Structural genomics for drug design against the pathogen Coxiella burnetii. Proteins, 83, 2015
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2X93
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![BU of 2x93 by Molmil](/molmil-images/mine/2x93) | Crystal structure of AnCE-trandolaprilat complex | Descriptor: | 2-acetamido-2-deoxy-beta-D-glucopyranose, 4-(2-HYDROXYETHYL)-1-PIPERAZINE ETHANESULFONIC ACID, ANGIOTENSIN CONVERTING ENZYME, ... | Authors: | Akif, M, Georgiadis, D, Mahajan, A, Dive, V, Sturrock, E.D, Isaac, R.E, Acharya, K.R. | Deposit date: | 2010-03-14 | Release date: | 2010-06-02 | Last modified: | 2020-07-29 | Method: | X-RAY DIFFRACTION (1.98 Å) | Cite: | High Resolution Crystal Structures of Drosophila Melanogaster Angiotensin Converting Enzyme in Complex with Novel Inhibitors and Anti- Hypertensive Drugs. J.Mol.Biol., 400, 2010
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4CA8
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![BU of 4ca8 by Molmil](/molmil-images/mine/4ca8) | Drosophila Angiotensin converting enzyme (AnCE) in complex with a phosphinic tripeptide FII | Descriptor: | 2-acetamido-2-deoxy-beta-D-glucopyranose, ANGIOTENSIN-CONVERTING ENZYME, SULFATE ION, ... | Authors: | Masuyer, G, Akif, M, Czarny, B, Beau, F, Schwager, S.L.U, Sturrock, E.D, Isaac, R.E, Dive, V, Acharya, K.R. | Deposit date: | 2013-10-07 | Release date: | 2013-12-11 | Last modified: | 2023-12-20 | Method: | X-RAY DIFFRACTION (1.99 Å) | Cite: | Crystal Structures of Highly Specific Phosphinic Tripeptide Enantiomers in Complex with the Angiotensin-I Converting Enzyme. FEBS J., 281, 2014
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2X2E
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![BU of 2x2e by Molmil](/molmil-images/mine/2x2e) | Dynamin GTPase dimer, long axis form | Descriptor: | DYNAMIN-1, GUANOSINE-5'-DIPHOSPHATE, MAGNESIUM ION, ... | Authors: | Chappie, J.S, Acharya, S, Leonard, M, Schmid, S.L, Dyda, F. | Deposit date: | 2010-01-12 | Release date: | 2010-04-28 | Last modified: | 2019-05-08 | Method: | X-RAY DIFFRACTION (2 Å) | Cite: | G Domain Dimerization Controls Dynamin'S Assembly-Stimulated Gtpase Activity. Nature, 465, 2010
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4BVS
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![BU of 4bvs by Molmil](/molmil-images/mine/4bvs) | Cyanuric acid hydrolase: evolutionary innovation by structural concatenation. | Descriptor: | 1,3,5-triazine-2,4,6-triamine, CYANURIC ACID AMIDOHYDROLASE, MAGNESIUM ION | Authors: | Peat, T.S, Balotra, S, Wilding, M, French, N.G, Briggs, L.J, Panjikar, S, Cowieson, N, Newman, J, Scott, C. | Deposit date: | 2013-06-28 | Release date: | 2013-07-17 | Last modified: | 2023-12-20 | Method: | X-RAY DIFFRACTION (2.6 Å) | Cite: | Cyanuric Acid Hydrolase: Evolutionary Innovation by Structural Concatenation. Mol.Microbiol., 88, 2013
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3AFQ
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![BU of 3afq by Molmil](/molmil-images/mine/3afq) | Crystal structure of the single-stranded DNA binding protein from Mycobacterium leprae (Form II) | Descriptor: | Single-stranded DNA-binding protein | Authors: | Kaushal, P.S, Singh, P, Sharma, A, Muniyappa, K, Vijayan, M. | Deposit date: | 2010-03-10 | Release date: | 2010-10-06 | Last modified: | 2023-11-01 | Method: | X-RAY DIFFRACTION (2.8 Å) | Cite: | X-ray and molecular-dynamics studies on Mycobacterium leprae single-stranded DNA-binding protein and comparison with other eubacterial SSB structures Acta Crystallogr.,Sect.D, 66, 2010
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4CIZ
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![BU of 4ciz by Molmil](/molmil-images/mine/4ciz) | Crystal structure of the complex of the Cellular Retinal Binding Protein with 9-cis-retinal | Descriptor: | L(+)-TARTARIC ACID, RETINAL, RETINALDEHYDE-BINDING PROTEIN 1 | Authors: | Bolze, C.S, Helbling, R.E, Owen, R.L, Pearson, A.R, Pompidor, G, Dworkowski, F, Fuchs, M.R, Furrer, J, Golczak, M, Palczewski, K, Cascella, M, Stocker, A. | Deposit date: | 2013-12-18 | Release date: | 2014-01-08 | Last modified: | 2023-12-20 | Method: | X-RAY DIFFRACTION (3.403 Å) | Cite: | Human Cellular Retinaldehyde-Binding Protein Has Secondary Thermal 9-Cis-Retinal Isomerase Activity. J.Am.Chem.Soc., 136, 2014
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2X8Y
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![BU of 2x8y by Molmil](/molmil-images/mine/2x8y) | Crystal structure of AnCE | Descriptor: | 2-acetamido-2-deoxy-beta-D-glucopyranose, ANGIOTENSIN CONVERTING ENZYME, CITRATE ANION, ... | Authors: | Akif, M, Georgiadis, D, Mahajan, A, Dive, V, Sturrock, E.D, Isaac, R.E, Acharya, K.R. | Deposit date: | 2010-03-14 | Release date: | 2010-06-02 | Last modified: | 2023-12-20 | Method: | X-RAY DIFFRACTION (1.9 Å) | Cite: | High Resolution Crystal Structures of Drosophila Melanogaster Angiotensin Converting Enzyme in Complex with Novel Inhibitors and Anti- Hypertensive Drugs. J.Mol.Biol., 400, 2010
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2X97
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![BU of 2x97 by Molmil](/molmil-images/mine/2x97) | Crystal structure of AnCE-RXP407 complex | Descriptor: | 2-acetamido-2-deoxy-beta-D-glucopyranose, ANGIOTENSIN CONVERTING ENZYME, N~2~-acetyl-N-{(1R)-1-[(S)-[(2S)-3-{[(2S)-1-amino-1-oxopropan-2-yl]amino}-2-methyl-3-oxopropyl](hydroxy)phosphoryl]-2-phenylethyl}-L-alpha-asparagine, ... | Authors: | Akif, M, Georgiadis, D, Mahajan, A, Dive, V, Sturrock, E.D, Isaac, R.E, Acharya, K.R. | Deposit date: | 2010-03-14 | Release date: | 2010-06-02 | Last modified: | 2020-07-29 | Method: | X-RAY DIFFRACTION (1.85 Å) | Cite: | High Resolution Crystal Structures of Drosophila Melanogaster Angiotensin Converting Enzyme in Complex with Novel Inhibitors and Anti- Hypertensive Drugs. J.Mol.Biol., 400, 2010
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2X92
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![BU of 2x92 by Molmil](/molmil-images/mine/2x92) | Crystal structure of AnCE-ramiprilat complex | Descriptor: | 2-acetamido-2-deoxy-beta-D-glucopyranose, 4-(2-HYDROXYETHYL)-1-PIPERAZINE ETHANESULFONIC ACID, ANGIOTENSIN CONVERTING ENZYME, ... | Authors: | Akif, M, Georgiadis, D, Mahajan, A, Dive, V, Sturrock, E.D, Isaac, R.E, Acharya, K.R. | Deposit date: | 2010-03-14 | Release date: | 2010-06-02 | Last modified: | 2020-07-29 | Method: | X-RAY DIFFRACTION (2.11 Å) | Cite: | High Resolution Crystal Structures of Drosophila Melanogaster Angiotensin Converting Enzyme in Complex with Novel Inhibitors and Anti- Hypertensive Drugs. J.Mol.Biol., 400, 2010
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4CXQ
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![BU of 4cxq by Molmil](/molmil-images/mine/4cxq) | Mycobaterium tuberculosis transaminase BioA complexed with substrate KAPA | Descriptor: | 1,2-ETHANEDIOL, 7-KETO-8-AMINOPELARGONIC ACID, ADENOSYLMETHIONINE-8-AMINO-7-OXONONANOATE AMINOTRANSFERASE, ... | Authors: | Dai, R, Wilson, D.J, Geders, T.W, Aldrich, C.C, Finzel, B.C. | Deposit date: | 2014-04-08 | Release date: | 2014-04-23 | Last modified: | 2023-12-20 | Method: | X-RAY DIFFRACTION (1.8 Å) | Cite: | Inhibition of Mycobacterium Tuberculosis Transaminase Bioa by Aryl Hydrazines and Hydrazides. Chembiochem, 15, 2014
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2WK5
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![BU of 2wk5 by Molmil](/molmil-images/mine/2wk5) | Structural features of native human thymidine phosphorylase and in complex with 5-iodouracil | Descriptor: | GLYCEROL, THYMIDINE PHOSPHORYLASE | Authors: | Mitsiki, E, Papageorgiou, A.C, Iyer, S, Thiyagarajan, N, Prior, S.H, Sleep, D, Finnis, C, Acharya, K.R. | Deposit date: | 2009-06-05 | Release date: | 2009-07-07 | Last modified: | 2023-12-13 | Method: | X-RAY DIFFRACTION (2.99 Å) | Cite: | Structures of Native Human Thymidine Phosphorylase and in Complex with 5-Iodouracil. Biochem.Biophys.Res.Commun., 386, 2009
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1UN5
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![BU of 1un5 by Molmil](/molmil-images/mine/1un5) | ARH-II, AN ANGIOGENIN/RNASE A CHIMERA | Descriptor: | ANGIOGENIN, CITRIC ACID | Authors: | Holloway, D.E, Baker, M.D, Acharya, K.R. | Deposit date: | 2003-09-04 | Release date: | 2004-02-06 | Last modified: | 2023-12-13 | Method: | X-RAY DIFFRACTION (2.6 Å) | Cite: | Crystallographic Studies on Structural Features that Determine the Enzymatic Specificity and Potency of Human Angiogenin: Thr44, Thr80 and Residues 38-41 Biochemistry, 43, 2004
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3ZUS
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![BU of 3zus by Molmil](/molmil-images/mine/3zus) | Crystal structure of an engineered botulinum neurotoxin type A- SNARE23 derivative, LC-A-SNAP23-Hn-A | Descriptor: | BOTULINUM NEUROTOXIN TYPE A, SYNAPTOSOMAL-ASSOCIATED PROTEIN 23, ZINC ION | Authors: | Masuyer, G, Stancombe, P, Chaddock, J.A, Acharya, K.R. | Deposit date: | 2011-07-19 | Release date: | 2011-12-07 | Last modified: | 2023-12-20 | Method: | X-RAY DIFFRACTION (2.95 Å) | Cite: | Structures of Engineered Clostridium Botulinum Neurotoxin Derivatives Acta Crystallogr.,Sect.F, 67, 2011
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2FKY
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![BU of 2fky by Molmil](/molmil-images/mine/2fky) | crystal structure of KSP in complex with inhibitor 13 | Descriptor: | (2S)-4-(2,5-DIFLUOROPHENYL)-N-METHYL-2-PHENYL-N-PIPERIDIN-4-YL-2,5-DIHYDRO-1H-PYRROLE-1-CARBOXAMIDE, ADENOSINE-5'-DIPHOSPHATE, Kinesin-like protein KIF11, ... | Authors: | Yan, Y. | Deposit date: | 2006-01-05 | Release date: | 2006-02-07 | Last modified: | 2024-02-14 | Method: | X-RAY DIFFRACTION (2.3 Å) | Cite: | Kinesin spindle protein (KSP) inhibitors. Part 2: the design, synthesis, and characterization of 2,4-diaryl-2,5-dihydropyrrole inhibitors of the mitotic kinesin KSP. Bioorg.Med.Chem.Lett., 16, 2006
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2PY2
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![BU of 2py2 by Molmil](/molmil-images/mine/2py2) | Structure of Herring Type II Antifreeze Protein | Descriptor: | Antifreeze protein type II, CALCIUM ION | Authors: | Liu, Y, Li, Z, Lin, Q, Seetharaman, J, Sivaraman, J, Hew, C.-L. | Deposit date: | 2007-05-15 | Release date: | 2007-06-26 | Last modified: | 2011-07-13 | Method: | X-RAY DIFFRACTION (1.7 Å) | Cite: | Structure and Evolutionary Origin of Ca-Dependent Herring Type II Antifreeze Protein. PLoS ONE, 2, 2007
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3ZBW
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![BU of 3zbw by Molmil](/molmil-images/mine/3zbw) | Crystal Structure of murine Angiogenin-3 | Descriptor: | ACETIC ACID, ANGIOGENIN-3, SULFATE ION, ... | Authors: | Iyer, S, Holloway, D.E, Acharya, K.R. | Deposit date: | 2012-11-13 | Release date: | 2012-12-26 | Last modified: | 2023-12-20 | Method: | X-RAY DIFFRACTION (1.801 Å) | Cite: | Crystal Structures of Murine Angiogenin-2 and -3 - Probing 'Structure - Function' Relationships Amongst Angiogenin Homologues. FEBS J., 280, 2013
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