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6ANQ
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BU of 6anq by Molmil
STRUCTURE OF HIV-1 REVERSE TRANSCRIPTASE (RT) TERNARY COMPLEX WITH A DOUBLE STRANDED DNA AND AN INCOMING D4TTP AT PH 8.5
Descriptor: 2',3'-DEHYDRO-2',3'-DEOXY-THYMIDINE 5'-TRIPHOSPHATE, DNA PRIMER (5'- D(*AP*CP*AP*GP*TP*CP*CP*CP*TP*GP*TP*TP*CP*GP*GP*GP*CP*GP*CP*CP*GP)-3'), DNA TEMPLATE (5'- D(*AP*TP*GP*AP*AP*CP*GP*GP*CP*GP*CP*CP*CP*GP*AP*AP*CP*AP*GP*GP*GP*AP*CP*TP*GP*TP*G)-3'), ...
Authors:Martinez, S.E, Das, K, Arnold, E.
Deposit date:2017-08-14
Release date:2018-08-15
Last modified:2023-10-04
Method:X-RAY DIFFRACTION (2.586 Å)
Cite:Structure of HIV-1 reverse transcriptase/d4TTP complex: Novel DNA cross-linking site and pH-dependent conformational changes.
Protein Sci., 28, 2019
7TGQ
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BU of 7tgq by Molmil
Zinc finger antiviral protein (ZAP) central domain bound to ADP-ribose
Descriptor: ACETATE ION, ADENOSINE-5-DIPHOSPHORIBOSE, ZINC ION, ...
Authors:Pornillos, O.P.
Deposit date:2022-01-09
Release date:2022-02-02
Last modified:2023-10-25
Method:X-RAY DIFFRACTION (2 Å)
Cite:Poly(ADP-ribose) potentiates ZAP antiviral activity.
Plos Pathog., 18, 2022
5OL8
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BU of 5ol8 by Molmil
Structure of human mitochondrial transcription elongation factor (TEFM) C-terminal domain
Descriptor: GLYCEROL, Transcription elongation factor, mitochondrial
Authors:Hillen, H.S, Parshin, A.V, Agaronyan, K, Morozov, Y, Graber, J.J, Chernev, A, Schwinghammer, K, Urlaub, H, Anikin, M, Cramer, P, Temiakov, D.
Deposit date:2017-07-27
Release date:2017-10-18
Last modified:2024-05-08
Method:X-RAY DIFFRACTION (1.9 Å)
Cite:Mechanism of Transcription Anti-termination in Human Mitochondria.
Cell, 171, 2017
6ASW
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BU of 6asw by Molmil
STRUCTURE OF HIV-1 REVERSE TRANSCRIPTASE (RT) TERNARY COMPLEX WITH A DOUBLE STRANDED DNA AND AN INCOMING D4TTP AT PH 9.0
Descriptor: 2',3'-DEHYDRO-2',3'-DEOXY-THYMIDINE 5'-TRIPHOSPHATE, DNA (27-MER), DNA (5'-D(*A*CP*AP*GP*TP*CP*CP*CP*TP*GP*TP*TP*CP*GP*GP*GP*CP*GP*CP*CP*(DDG))-3'), ...
Authors:Martinez, S.E, Das, K, Arnold, E.
Deposit date:2017-08-25
Release date:2018-08-15
Last modified:2023-10-04
Method:X-RAY DIFFRACTION (2.605 Å)
Cite:Structure of HIV-1 reverse transcriptase/d4TTP complex: Novel DNA cross-linking site and pH-dependent conformational changes.
Protein Sci., 28, 2019
5OL9
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BU of 5ol9 by Molmil
Structure of human mitochondrial transcription elongation factor (TEFM) N-terminal domain
Descriptor: ACETATE ION, Transcription elongation factor, mitochondrial
Authors:Hillen, H.S, Parshin, A.V, Agaronyan, K, Morozov, Y, Graber, J.J, Chernev, A, Schwinghammer, K, Urlaub, H, Anikin, M, Cramer, P, Temiakov, D.
Deposit date:2017-07-27
Release date:2017-10-18
Last modified:2024-05-08
Method:X-RAY DIFFRACTION (1.302 Å)
Cite:Mechanism of Transcription Anti-termination in Human Mitochondria.
Cell, 171, 2017
6D0Y
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BU of 6d0y by Molmil
X-ray Crystal Structure of PGC-1beta C-terminus bound to the CBP80-CBP20 Cap Binding Complex
Descriptor: MAGNESIUM ION, Nuclear cap-binding protein subunit 1, Nuclear cap-binding protein subunit 2, ...
Authors:Gleghorn, M.L, Maquat, L.E.
Deposit date:2018-04-11
Release date:2018-04-25
Last modified:2020-01-01
Method:X-RAY DIFFRACTION (2.676 Å)
Cite:Transcriptional coactivator PGC-1 alpha contains a novel CBP80-binding motif that orchestrates efficient target gene expression.
Genes Dev., 32, 2018
7YI1
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BU of 7yi1 by Molmil
Cryo-EM structure of Eaf3 CHD bound to H3K36me3 nucleosome
Descriptor: Chromatin modification-related protein EAF3, Histone H2A, Histone H2B 1.1, ...
Authors:Li, H.T, Yan, C.Y, Guan, H.P, Wang, P.
Deposit date:2022-07-14
Release date:2023-06-14
Last modified:2023-08-30
Method:ELECTRON MICROSCOPY (2.8 Å)
Cite:Diverse modes of H3K36me3-guided nucleosomal deacetylation by Rpd3S.
Nature, 620, 2023
8OOY
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BU of 8ooy by Molmil
Pol I bound to extended and displaced DNA section - open conformation
Descriptor: DNA polymerase I, Displacing Primer, Extending Primer, ...
Authors:Botto, M, Borsellini, A, Lamers, M.H.
Deposit date:2023-04-06
Release date:2023-08-09
Last modified:2023-11-01
Method:ELECTRON MICROSCOPY (4 Å)
Cite:A four-point molecular handover during Okazaki maturation.
Nat.Struct.Mol.Biol., 30, 2023
8OO6
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BU of 8oo6 by Molmil
Pol I bound to extended and displaced DNA section - closed conformation
Descriptor: DNA polymerase I, Displaced primer, Extending Primer, ...
Authors:Botto, M, Borsellini, A, Lamers, M.H.
Deposit date:2023-04-04
Release date:2023-08-09
Last modified:2023-11-01
Method:ELECTRON MICROSCOPY (4.3 Å)
Cite:A four-point molecular handover during Okazaki maturation.
Nat.Struct.Mol.Biol., 30, 2023
8AS5
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BU of 8as5 by Molmil
CryoEM structure of the human Nucleophosmin 1 core
Descriptor: Nucleophosmin
Authors:Valentin Gese, G, Hallberg, B.M.
Deposit date:2022-08-18
Release date:2023-02-15
Last modified:2024-07-24
Method:ELECTRON MICROSCOPY (3.53 Å)
Cite:A "grappling hook" interaction connects self-assembly and chaperone activity of Nucleophosmin 1.
Pnas Nexus, 2, 2023
8YD7
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BU of 8yd7 by Molmil
Structure of FADD/Caspase-8/cFLIP death effector domain assembly
Descriptor: CASP8 and FADD-like apoptosis regulator subunit p12, Caspase-8, FAS-associated death domain protein, ...
Authors:Lin, S.-C, Yang, C.-Y.
Deposit date:2024-02-19
Release date:2024-05-15
Method:X-RAY DIFFRACTION (3.32 Å)
Cite:Deciphering DED assembly mechanisms in FADD-procaspase-8-cFLIP complexes regulating apoptosis.
Nat Commun, 15, 2024
8YBX
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BU of 8ybx by Molmil
Structure of the FADD/Caspase-8/cFLIP death effector domain assembly
Descriptor: CASP8 and FADD-like apoptosis regulator subunit p43, Caspase-8 subunit p10, FAS-associated death domain protein
Authors:Lin, S.-C, Yang, C.-Y.
Deposit date:2024-02-16
Release date:2024-05-15
Method:ELECTRON MICROSCOPY (3.68 Å)
Cite:Deciphering DED assembly mechanisms in FADD-procaspase-8-cFLIP complexes regulating apoptosis.
Nat Commun, 15, 2024
6AN2
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BU of 6an2 by Molmil
STRUCTURE OF HIV-1 REVERSE TRANSCRIPTASE (RT) TERNARY COMPLEX WITH A DOUBLE STRANDED DNA AND AN INCOMING D4TTP AT PH 7.5
Descriptor: 2',3'-DEHYDRO-2',3'-DEOXY-THYMIDINE 5'-TRIPHOSPHATE, DNA PRIMER (5'- D(*AP*CP*AP*GP*TP*CP*CP*CP*TP*GP*TP*TP*CP*GP*GP*GP*CP*GP*CP*CP*GP)-3'), DNA TEMPLATE (5'- D(*AP*TP*GP*AP*AP*CP*GP*GP*CP*GP*CP*CP*CP*GP*AP*AP*CP*AP*GP*GP*GP*AP*CP*TP*GP*TP*G)-3'), ...
Authors:Martinez, S.E, Das, K, Arnold, E.
Deposit date:2017-08-11
Release date:2018-08-15
Last modified:2023-10-04
Method:X-RAY DIFFRACTION (2.7 Å)
Cite:Structure of HIV-1 reverse transcriptase/d4TTP complex: Novel DNA cross-linking site and pH-dependent conformational changes.
Protein Sci., 28, 2019
6AVT
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BU of 6avt by Molmil
STRUCTURE OF HIV-1 REVERSE TRANSCRIPTASE (RT) TERNARY COMPLEX WITH A DOUBLE STRANDED DNA AND AN INCOMING D4TTP AT PH 9.5 WITH CROSS-LINKING TO FIRST BASE TEMPLATE OVERHANG
Descriptor: 2',3'-DEHYDRO-2',3'-DEOXY-THYMIDINE 5'-TRIPHOSPHATE, DNA (27-MER), DNA (5'-D(*A*CP*AP*GP*TP*CP*CP*CP*TP*GP*TP*TP*CP*GP*GP*GP*CP*GP*CP*CP*(DDG))-3'), ...
Authors:Martinez, S.E, Das, K, Arnold, E.
Deposit date:2017-09-04
Release date:2018-08-15
Last modified:2023-10-04
Method:X-RAY DIFFRACTION (2.603 Å)
Cite:Structure of HIV-1 reverse transcriptase/d4TTP complex: Novel DNA cross-linking site and pH-dependent conformational changes.
Protein Sci., 28, 2019
4HRE
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BU of 4hre by Molmil
Crystal Structure of p11/Annexin A2 Heterotetramer in Complex with SMARCA3 Peptide
Descriptor: Annexin A2, Helicase-like transcription factor, Protein S100-A10
Authors:Gao, P, Patel, D.J.
Deposit date:2012-10-27
Release date:2013-03-06
Last modified:2023-09-20
Method:X-RAY DIFFRACTION (2.7852 Å)
Cite:SMARCA3, a Chromatin-Remodeling Factor, Is Required for p11-Dependent Antidepressant Action.
Cell(Cambridge,Mass.), 152, 2013
6EZE
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BU of 6eze by Molmil
The open conformation of E.coli Elongation Factor Tu in complex with GDPNP.
Descriptor: DI(HYDROXYETHYL)ETHER, Elongation factor Tu 2, GLYCEROL, ...
Authors:Johansen, J.S, Blaise, M, Thirup, S.S.
Deposit date:2017-11-15
Release date:2018-08-22
Last modified:2024-01-17
Method:X-RAY DIFFRACTION (2.47 Å)
Cite:E. coli elongation factor Tu bound to a GTP analogue displays an open conformation equivalent to the GDP-bound form.
Nucleic Acids Res., 46, 2018
6AN8
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BU of 6an8 by Molmil
STRUCTURE OF HIV-1 REVERSE TRANSCRIPTASE (RT) TERNARY COMPLEX WITH A DOUBLE STRANDED DNA AND AN INCOMING D4TTP AT PH 8.0
Descriptor: 2',3'-DEHYDRO-2',3'-DEOXY-THYMIDINE 5'-TRIPHOSPHATE, DNA PRIMER (5'- D(*AP*CP*AP*GP*TP*CP*CP*CP*TP*GP*TP*TP*CP*GP*GP*GP*CP*GP*CP*CP*GP)-3'), DNA TEMPLATE (5'- D(*AP*TP*GP*AP*AP*CP*GP*GP*CP*GP*CP*CP*CP*GP*AP*AP*CP*AP*GP*GP*GP*AP*CP*TP*GP*TP*G)-3'), ...
Authors:Martinez, S.E, Das, K, Arnold, E.
Deposit date:2017-08-12
Release date:2018-08-15
Last modified:2023-10-04
Method:X-RAY DIFFRACTION (2.596 Å)
Cite:Structure of HIV-1 reverse transcriptase/d4TTP complex: Novel DNA cross-linking site and pH-dependent conformational changes.
Protein Sci., 28, 2019
1N54
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BU of 1n54 by Molmil
Cap Binding Complex m7GpppG free
Descriptor: 20 kDa nuclear cap binding protein, 80 kDa nuclear cap binding protein, GLYCEROL
Authors:Calero, G, Wilson, K, Ly, T, Rios-Steiner, J, Clardy, J, Cerione, R.
Deposit date:2002-11-04
Release date:2003-02-18
Last modified:2024-02-14
Method:X-RAY DIFFRACTION (2.72 Å)
Cite:Structural basis of m7GpppG binding to the nuclear cap-binding protein complex.
Nat.Struct.Biol., 9, 2002
6AVM
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BU of 6avm by Molmil
STRUCTURE OF HIV-1 REVERSE TRANSCRIPTASE (RT) TERNARY COMPLEX WITH A DOUBLE STRANDED DNA AND AN INCOMING D4TTP AT PH 9.5 WITH CROSS-LINKING TO SECOND BASE TEMPLATE OVERHANG
Descriptor: 2',3'-DEHYDRO-2',3'-DEOXY-THYMIDINE 5'-TRIPHOSPHATE, DNA (27-MER), DNA (5'-D(*A*CP*AP*GP*TP*CP*CP*CP*TP*GP*TP*TP*CP*GP*GP*GP*CP*GP*CP*CP*(DDG))-3'), ...
Authors:Martinez, S.E, Das, K, Arnold, E.
Deposit date:2017-09-03
Release date:2018-08-15
Last modified:2023-10-04
Method:X-RAY DIFFRACTION (2.502 Å)
Cite:Structure of HIV-1 reverse transcriptase/d4TTP complex: Novel DNA cross-linking site and pH-dependent conformational changes.
Protein Sci., 28, 2019
5BSA
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BU of 5bsa by Molmil
Structure of histone H3/H4 in complex with Spt2
Descriptor: Histone H3.2, Histone H4, Protein SPT2 homolog
Authors:Chen, S, Patel, D.J.
Deposit date:2015-06-01
Release date:2015-07-08
Last modified:2023-11-15
Method:X-RAY DIFFRACTION (4.611 Å)
Cite:Structure-function studies of histone H3/H4 tetramer maintenance during transcription by chaperone Spt2.
Genes Dev., 29, 2015
5HHK
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BU of 5hhk by Molmil
Reverse transcriptase domain of group II intron maturase from Roseburia intestinalis in P21 space group (Se-MET)
Descriptor: (4S)-2-METHYL-2,4-PENTANEDIOL, GLYCINE, PHOSPHATE ION, ...
Authors:Zhao, C, Pyle, A.M.
Deposit date:2016-01-11
Release date:2016-05-04
Last modified:2019-12-25
Method:X-RAY DIFFRACTION (1.4 Å)
Cite:Crystal structures of a group II intron maturase reveal a missing link in spliceosome evolution.
Nat.Struct.Mol.Biol., 23, 2016
5HHL
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BU of 5hhl by Molmil
Reverse transcriptase domain of group II intron maturase from Eubacterium rectale in P21 space group
Descriptor: POTASSIUM ION, Retron-type reverse transcriptase
Authors:Zhao, C, Pyle, A.M.
Deposit date:2016-01-11
Release date:2016-05-04
Last modified:2023-09-27
Method:X-RAY DIFFRACTION (2.1 Å)
Cite:Crystal structures of a group II intron maturase reveal a missing link in spliceosome evolution.
Nat.Struct.Mol.Biol., 23, 2016
5LYS
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BU of 5lys by Molmil
The crystal structure of 7SK 5'-hairpin - Gold derivative
Descriptor: 7SK RNA, GOLD ION, MAGNESIUM ION, ...
Authors:Martinez-Zapien, D, Legrand, P, McEwen, A.G, Pasquali, S, Dock-Bregeon, A.-C.
Deposit date:2016-09-28
Release date:2017-01-25
Last modified:2024-05-01
Method:X-RAY DIFFRACTION (2.32 Å)
Cite:The crystal structure of the 5 functional domain of the transcription riboregulator 7SK.
Nucleic Acids Res., 45, 2017
1H6K
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BU of 1h6k by Molmil
nuclear Cap Binding Complex
Descriptor: 20 KDA NUCLEAR CAP BINDING PROTEIN, CBP80
Authors:Mazza, C, Ohno, M, Segref, A, Mattaj, I.W, Cusack, S.
Deposit date:2001-06-18
Release date:2001-09-13
Last modified:2024-05-08
Method:X-RAY DIFFRACTION (2 Å)
Cite:Crystal Structure of the Human Nuclear CAP Binding Complex
Mol.Cell, 8, 2001
5LYV
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BU of 5lyv by Molmil
The crystal structure of 7SK 5'-hairpin - Osmium derivative
Descriptor: 7SK RNA, CHLORIDE ION, MAGNESIUM ION, ...
Authors:Martinez-Zapien, D, Legrand, P, McEwen, A.G, Pasquali, S, Dock-Bregeon, A.-C.
Deposit date:2016-09-28
Release date:2017-01-25
Last modified:2024-02-07
Method:X-RAY DIFFRACTION (2.35 Å)
Cite:The crystal structure of the 5 functional domain of the transcription riboregulator 7SK.
Nucleic Acids Res., 45, 2017

224572

數據於2024-09-04公開中

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