8AS5

CryoEM structure of the human Nucleophosmin 1 core

Summary for 8AS5

Entry DOI	10.2210/pdb8as5/pdb
EMDB information	15606
Descriptor	Nucleophosmin (1 entity in total)
Functional Keywords	phase separation, chaperone
Biological source	Homo sapiens (human)
Total number of polymer chains	5
Total formula weight	163540.70
Authors	Valentin Gese, G.,Hallberg, B.M. (deposition date: 2022-08-18, release date: 2023-02-15)
Primary citation	Saluri, M.,Leppert, A.,Gese, G.V.,Sahin, C.,Lama, D.,Kaldmae, M.,Chen, G.,Elofsson, A.,Allison, T.M.,Arsenian-Henriksson, M.,Johansson, J.,Lane, D.P.,Hallberg, B.M.,Landreh, M. A "grappling hook" interaction connects self-assembly and chaperone activity of Nucleophosmin 1. Pnas Nexus, 2:pgac303-pgac303, 2023 Cited by PubMed: 36743470 DOI: 10.1093/pnasnexus/pgac303 PDB entries with the same primary citation
Experimental method	ELECTRON MICROSCOPY (2.5 Å)

Structure validation