PDB: 14265 resultsInfo pagesStatus searchChemie searchBIRD

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2P69	Crystal Structure of Human Pyridoxal Phosphate Phosphatase with PLP Descriptor: CALCIUM ION, PYRIDOXAL-5'-PHOSPHATE, Pyridoxal phosphate phosphatase Authors: Ramagopal, U.A, Freeman, J, Izuka, M, Toro, R, Sauder, J.M, Burley, S.K, Almo, S.C, New York SGX Research Center for Structural Genomics (NYSGXRC) Deposit date: 2007-03-16 Release date: 2007-04-03 Last modified: 2023-11-15 Method: X-RAY DIFFRACTION (2.25 Å) Cite: Structural genomics of protein phosphatases. J.Struct.Funct.Genom., 8, 2007
2DR5	Complex structure of CCA adding enzyme with mini-helix lacking CCA Descriptor: CCA-adding enzyme, SULFATE ION, tRNA (32-MER) Authors: Tomita, K, Ishitani, R, Fukai, S, Nureki, O. Deposit date: 2006-06-08 Release date: 2006-10-31 Last modified: 2023-10-25 Method: X-RAY DIFFRACTION (2.8 Å) Cite: Complete crystallographic analysis of the dynamics of CCA sequence addition Nature, 443, 2006
2DVI	Complex structure of CCA-adding enzyme, mini-DCC and CTP Descriptor: CCA-adding enzyme, CYTIDINE-5'-TRIPHOSPHATE, MAGNESIUM ION, ... Authors: Tomita, K, Ishitani, R, Fukai, S, Nureki, O. Deposit date: 2006-07-31 Release date: 2006-11-14 Last modified: 2023-10-25 Method: X-RAY DIFFRACTION (2.61 Å) Cite: Complete crystallographic analysis of the dynamics of CCA sequence addition Nature, 443, 2006
5OP0	Structure of Prim-PolC from Mycobacterium smegmatis Descriptor: DNA polymerase LigD, polymerase domain Authors: Brissett, N.C, Doherty, A.J. Deposit date: 2017-08-09 Release date: 2017-11-15 Last modified: 2024-01-17 Method: X-RAY DIFFRACTION (1.84 Å) Cite: DNA Ligase C and Prim-PolC participate in base excision repair in mycobacteria. Nat Commun, 8, 2017
6Z2K	The structure of the tetrameric HDAC1/MIDEAS/DNTTIP1 MiDAC deacetylase complex Descriptor: Deoxynucleotidyltransferase terminal-interacting protein 1, Histone deacetylase 1, INOSITOL HEXAKISPHOSPHATE, ... Authors: Fairall, L, Saleh, A, Ragan, T.J, Millard, C.J, Savva, C.G, Schwabe, J.W.R. Deposit date: 2020-05-16 Release date: 2020-07-08 Last modified: 2024-05-22 Method: ELECTRON MICROSCOPY (4.5 Å) Cite: The MiDAC histone deacetylase complex is essential for embryonic development and has a unique multivalent structure. Nat Commun, 11, 2020
3NEW	p38-alpha complexed with Compound 10 Descriptor: 4-(trifluoromethyl)-3-[3-(trifluoromethyl)phenyl]-1,7-dihydro-6H-pyrazolo[3,4-b]pyridin-6-one, Mitogen-activated protein kinase 14 Authors: Goedken, E.R, Comess, K.M, Sun, C, Argiriadi, M, Jia, Y, Quinn, C.M, Banach, D.L, Marcotte, D, Borhani, D. Deposit date: 2010-06-09 Release date: 2010-12-01 Last modified: 2024-02-21 Method: X-RAY DIFFRACTION (2.51 Å) Cite: Discovery and Characterization of Non-ATP Site Inhibitors of the Mitogen Activated Protein (MAP) Kinases. Acs Chem.Biol., 6, 2011
6KE6	3.4 angstrom cryo-EM structure of yeast 90S small subunit preribosome Descriptor: 13 kDa ribonucleoprotein-associated protein, 18S rRNA, 40S ribosomal protein S1-A, ... Authors: Du, Y, Ye, K, An, W. Deposit date: 2019-07-03 Release date: 2020-08-05 Last modified: 2024-03-27 Method: ELECTRON MICROSCOPY (3.4 Å) Cite: 3.4 angstrom cryo-EM structure of yeast 90S small subunit preribosome To be published
7S4E	Crystal Structure of ligand ACBi1 in complex with bromodomain of human Smarca2 and pVHL:ElonginC:ElonginB complex Descriptor: 1,2-ETHANEDIOL, DI(HYDROXYETHYL)ETHER, Elongin-B, ... Authors: MacPherson, D.J, Sherman, W. Deposit date: 2021-09-08 Release date: 2022-10-05 Last modified: 2023-10-25 Method: X-RAY DIFFRACTION (2.25 Å) Cite: Predicting the structural basis of targeted protein degradation by integrating molecular dynamics simulations with structural mass spectrometry. Nat Commun, 13, 2022
5BTH	Crystal structure of Candida albicans Rai1 Descriptor: Decapping nuclease RAI1 Authors: Wang, V.Y, Tong, L. Deposit date: 2015-06-03 Release date: 2015-07-08 Last modified: 2024-03-06 Method: X-RAY DIFFRACTION (2.2 Å) Cite: Structural and biochemical studies of the distinct activity profiles of Rai1 enzymes. Nucleic Acids Res., 43, 2015
8Q87	Structure of the G. gallus 80S rotated ribosome in complex with eEF2 and SERBP1 Descriptor: 18S rRNA, 28S rRNA, 40S ribosomal protein S11, ... Authors: Nurullina, L, Jenner, L, Yusupov, M. Deposit date: 2023-08-18 Release date: 2024-08-28 Method: ELECTRON MICROSCOPY (2.4 Å) Cite: Structural insights into inactive ribosome complexes derived from cold-treated chick embryo cells To Be Published
5BTO	Crystal structure of Scheffersomyces stipitis Rai1 Descriptor: SsRai1 Authors: Wang, V.Y, Tong, L. Deposit date: 2015-06-03 Release date: 2015-07-08 Last modified: 2024-03-06 Method: X-RAY DIFFRACTION (1.641 Å) Cite: Structural and biochemical studies of the distinct activity profiles of Rai1 enzymes. Nucleic Acids Res., 43, 2015
8Q7Z	Structure of the G. gallus 80S non-rotated ribosome Descriptor: 18S rRNA, 28S rRNA, 40S ribosomal protein S11, ... Authors: Nurullina, L, Jenner, L, Yusupov, M. Deposit date: 2023-08-17 Release date: 2024-08-28 Method: ELECTRON MICROSCOPY (2.5 Å) Cite: Structural insights into inactive ribosome complexes derived from cold-treated chick embryo cells To Be Published
5IY4	Crystal structure of human PCNA in complex with the PIP box of DVC1 Descriptor: DVC1 PIP box, Proliferating cell nuclear antigen Authors: Jiang, T, Xu, M, Wang, Y. Deposit date: 2016-03-24 Release date: 2016-06-08 Last modified: 2024-10-30 Method: X-RAY DIFFRACTION (2.945 Å) Cite: Crystal structure of human PCNA in complex with the PIP box of DVC1 Biochem.Biophys.Res.Commun., 474, 2016
4M4Q	6-(4-fluorophenyl)-3-hydroxy-5-[4-(1H-1,2,3,4-tetrazol-5-yl)phenyl] -1,2-dihydropyridin-2-one bound to influenza 2009 H1N1 endonuclease Descriptor: 6-(4-fluorophenyl)-5-[4-(1H-tetrazol-5-yl)phenyl]pyridine-2,3-diol, MAGNESIUM ION, MANGANESE (II) ION, ... Authors: Bauman, J.D, Patel, D, Das, K, Arnold, E. Deposit date: 2013-08-07 Release date: 2013-09-18 Last modified: 2023-09-20 Method: X-RAY DIFFRACTION (2.502 Å) Cite: Crystallographic fragment screening and structure-based optimization yields a new class of influenza endonuclease inhibitors. Acs Chem.Biol., 8, 2013
4M5Q	High-resolution apo influenza 2009 H1N1 endonuclease structure Descriptor: 1,2-ETHANEDIOL, MANGANESE (II) ION, Polymerase PA Authors: Bauman, J.D, Patel, D, Das, K, Arnold, E. Deposit date: 2013-08-08 Release date: 2013-09-18 Last modified: 2024-02-28 Method: X-RAY DIFFRACTION (1.534 Å) Cite: Crystallographic fragment screening and structure-based optimization yields a new class of influenza endonuclease inhibitors. Acs Chem.Biol., 8, 2013
4M5R	High-resolution influenza 2009 H1N1 endonuclease bound to 4-(1H-IMIDAZOL-1-YL)PHENOL Descriptor: 1,2-ETHANEDIOL, 4-(1H-IMIDAZOL-1-YL)PHENOL, MANGANESE (II) ION, ... Authors: Bauman, J.D, Patel, D, Das, K, Arnold, E. Deposit date: 2013-08-08 Release date: 2013-09-18 Last modified: 2024-02-28 Method: X-RAY DIFFRACTION (1.4 Å) Cite: Crystallographic fragment screening and structure-based optimization yields a new class of influenza endonuclease inhibitors. Acs Chem.Biol., 8, 2013
4M5O	3-HYDROXY-6-PHENYL-1,2-DIHYDROPYRIDIN-2-ONE bound to influenza 2009 H1N1 endonuclease Descriptor: 1,2-ETHANEDIOL, 3-hydroxy-6-phenylpyridin-2(5H)-one, MANGANESE (II) ION, ... Authors: Bauman, J.D, Patel, D, Das, K, Arnold, E. Deposit date: 2013-08-08 Release date: 2013-09-18 Last modified: 2024-02-28 Method: X-RAY DIFFRACTION (2 Å) Cite: Crystallographic fragment screening and structure-based optimization yields a new class of influenza endonuclease inhibitors. Acs Chem.Biol., 8, 2013
5BSA	Structure of histone H3/H4 in complex with Spt2 Descriptor: Histone H3.2, Histone H4, Protein SPT2 homolog Authors: Chen, S, Patel, D.J. Deposit date: 2015-06-01 Release date: 2015-07-08 Last modified: 2024-10-23 Method: X-RAY DIFFRACTION (4.611 Å) Cite: Structure-function studies of histone H3/H4 tetramer maintenance during transcription by chaperone Spt2. Genes Dev., 29, 2015
4WBB	Single Turnover Autophosphorylation Cycle of the PKA RIIb Holoenzyme Descriptor: ADENOSINE-5'-DIPHOSPHATE, CALCIUM ION, cAMP-dependent protein kinase catalytic subunit alpha, ... Authors: Zhang, P, Knape, M.J, Ahuja, L.G, Keshwani, M.M, King, C.C, Sastri, M, Herberg, F.W, Taylor, S.S. Deposit date: 2014-09-02 Release date: 2015-05-20 Last modified: 2024-10-30 Method: X-RAY DIFFRACTION (2.8 Å) Cite: Single Turnover Autophosphorylation Cycle of the PKA RII beta Holoenzyme. Plos Biol., 13, 2015
5BS7	Structure of histone H3/H4 in complex with Spt2 Descriptor: Histone H3.2, Histone H4, Protein SPT2 homolog, ... Authors: Chen, S, Patel, D.J. Deposit date: 2015-06-01 Release date: 2015-07-08 Last modified: 2023-09-27 Method: X-RAY DIFFRACTION (3.3 Å) Cite: Structure-function studies of histone H3/H4 tetramer maintenance during transcription by chaperone Spt2. Genes Dev., 29, 2015
7D63	Cryo-EM structure of 90S preribosome with inactive Utp24 (state C) Descriptor: 13 kDa ribonucleoprotein-associated protein, 18S rRNA, 40S ribosomal protein S1-A, ... Authors: Du, Y, Zhang, J, An, W, Ye, K. Deposit date: 2020-09-29 Release date: 2021-10-06 Last modified: 2024-05-29 Method: ELECTRON MICROSCOPY (12.3 Å) Cite: Cryo-EM structure of 90S preribosome with inactive Utp24 (state C) To Be Published
7D5S	Cryo-EM structure of 90S preribosome with inactive Utp24 (state A2) Descriptor: 13 kDa ribonucleoprotein-associated protein, 18S rRNA, 40S ribosomal protein S12, ... Authors: Du, Y, Zhang, J, An, W, Ye, K. Deposit date: 2020-09-28 Release date: 2021-10-06 Last modified: 2024-05-29 Method: ELECTRON MICROSCOPY (4.6 Å) Cite: Cryo-EM structure of 90S preribosome with inactive Utp24 (state A2) To Be Published
9FQ0	Human NatA-NAC-MAP1 80S ribosome complex Descriptor: 28S rRNA, 5.8S rRNA, 60S ribosomal protein L19, ... Authors: Klein, M.A, Wild, K, Sinning, I. Deposit date: 2024-06-14 Release date: 2024-07-03 Last modified: 2024-10-02 Method: ELECTRON MICROSCOPY (4.67 Å) Cite: Multi-protein assemblies orchestrate co-translational enzymatic processing on the human ribosome. Nat Commun, 15, 2024
5O9Z	Cryo-EM structure of a pre-catalytic human spliceosome primed for activation (B complex) Descriptor: 116 kDa U5 small nuclear ribonucleoprotein component, Homo sapiens RNA, U6 small nuclear 1 (RNU6-1), ... Authors: Bertram, K, Kastner, B. Deposit date: 2017-06-20 Release date: 2017-08-16 Last modified: 2018-10-24 Method: ELECTRON MICROSCOPY (4.5 Å) Cite: Cryo-EM Structure of a Pre-catalytic Human Spliceosome Primed for Activation. Cell, 170, 2017
5BUH	Influenza PB2 bound to a hydroxymethyl azaindole inhibitor Descriptor: N-[(1R,3S)-3-({5-fluoro-2-[5-fluoro-2-(hydroxymethyl)-1H-pyrrolo[2,3-b]pyridin-3-yl]pyrimidin-4-yl}amino)cyclohexyl]pyrrolidine-1-carboxamide, Polymerase basic protein 2 Authors: Jacobs, M.D. Deposit date: 2015-06-03 Release date: 2016-06-08 Last modified: 2024-03-06 Method: X-RAY DIFFRACTION (2.55 Å) Cite: Novel 2-Substituted 7-Azaindole and 7-Azaindazole Analogues as Potential Antiviral Agents for the Treatment of Influenza. ACS Med Chem Lett, 8, 2017

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