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7F90
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BU of 7f90 by Molmil
Crystal structure of SARS auxiliary protein in complex with human nuclear protein
Descriptor: Nuclear pore complex protein Nup98-Nup96, ORF6 protein, mRNA export factor
Authors:Gao, X, Cui, S.
Deposit date:2021-07-03
Release date:2022-09-14
Last modified:2023-11-29
Method:X-RAY DIFFRACTION (2.39 Å)
Cite:Structural basis for Sarbecovirus ORF6 mediated blockage of nucleocytoplasmic transport
Nat Commun, 13, 2022
5BS7
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BU of 5bs7 by Molmil
Structure of histone H3/H4 in complex with Spt2
Descriptor: Histone H3.2, Histone H4, Protein SPT2 homolog, ...
Authors:Chen, S, Patel, D.J.
Deposit date:2015-06-01
Release date:2015-07-08
Last modified:2023-09-27
Method:X-RAY DIFFRACTION (3.3 Å)
Cite:Structure-function studies of histone H3/H4 tetramer maintenance during transcription by chaperone Spt2.
Genes Dev., 29, 2015
6B09
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BU of 6b09 by Molmil
Crystal structure of HsNUDT16 in complex with diADPR (soaked)
Descriptor: CHLORIDE ION, MAGNESIUM ION, SODIUM ION, ...
Authors:Thirawatananond, P, Gabelli, S.B.
Deposit date:2017-09-14
Release date:2019-01-09
Last modified:2024-03-13
Method:X-RAY DIFFRACTION (3.2 Å)
Cite:Structural analyses of NudT16-ADP-ribose complexes direct rational design of mutants with improved processing of poly(ADP-ribosyl)ated proteins.
Sci Rep, 9, 2019
6P94
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BU of 6p94 by Molmil
Human APE1 C65A AP-endonuclease product complex
Descriptor: 1,2-ETHANEDIOL, CHLORIDE ION, DI(HYDROXYETHYL)ETHER, ...
Authors:Whitaker, A.W, Stark, W.J, Freudenthal, B.D.
Deposit date:2019-06-09
Release date:2020-01-01
Last modified:2023-10-11
Method:X-RAY DIFFRACTION (2.09 Å)
Cite:Functions of the major abasic endonuclease (APE1) in cell viability and genotoxin resistance.
Mutagenesis, 35, 2020
6P93
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BU of 6p93 by Molmil
Human APE1 K98A AP-endonuclease product complex
Descriptor: 1,2-ETHANEDIOL, CHLORIDE ION, DI(HYDROXYETHYL)ETHER, ...
Authors:Whitaker, A.W, Stark, W.J, Freudenthal, B.D.
Deposit date:2019-06-09
Release date:2020-01-01
Last modified:2023-10-11
Method:X-RAY DIFFRACTION (2.1 Å)
Cite:Functions of the major abasic endonuclease (APE1) in cell viability and genotoxin resistance.
Mutagenesis, 35, 2020
3FEY
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BU of 3fey by Molmil
Crystal structure of the CBC-importin alpha complex.
Descriptor: Importin subunit alpha-2, Nuclear cap-binding protein subunit 1, Nuclear cap-binding protein subunit 2
Authors:Dias, S.M.G, Ambrosio, A.L.B, Cerione, R.A.
Deposit date:2008-12-01
Release date:2009-08-11
Last modified:2023-09-06
Method:X-RAY DIFFRACTION (2.2 Å)
Cite:The molecular basis for the regulation of the cap-binding complex by the importins.
Nat.Struct.Mol.Biol., 16, 2009
1H6K
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BU of 1h6k by Molmil
nuclear Cap Binding Complex
Descriptor: 20 KDA NUCLEAR CAP BINDING PROTEIN, CBP80
Authors:Mazza, C, Ohno, M, Segref, A, Mattaj, I.W, Cusack, S.
Deposit date:2001-06-18
Release date:2001-09-13
Last modified:2024-05-08
Method:X-RAY DIFFRACTION (2 Å)
Cite:Crystal Structure of the Human Nuclear CAP Binding Complex
Mol.Cell, 8, 2001
3FEX
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BU of 3fex by Molmil
Crystal structure of the CBC-importin alpha complex.
Descriptor: Importin subunit alpha-2, Nuclear cap-binding protein subunit 1, Nuclear cap-binding protein subunit 2
Authors:Dias, S.M.G, Ambrosio, A.L.B, Cerione, R.A.
Deposit date:2008-12-01
Release date:2009-08-11
Last modified:2023-09-06
Method:X-RAY DIFFRACTION (3.549 Å)
Cite:The molecular basis for the regulation of the cap-binding complex by the importins.
Nat.Struct.Mol.Biol., 16, 2009
8RJD
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BU of 8rjd by Molmil
Structure of the rabbit 80S ribosome stalled on a 2-TMD rhodopsin intermediate in complex with Sec61-TRAP, open conformation 2
Descriptor: 28S rRNA, 5.8S rRNA, 5S rRNA, ...
Authors:Lewis, A.J.O, Hegde, R.S.
Deposit date:2023-12-20
Release date:2024-01-24
Method:ELECTRON MICROSCOPY (2.78574 Å)
Cite:Structure of the rabbit 80S ribosome stalled on a 2-TMD rhodopsin intermediate in complex with Sec61-TRAP, open conformation 2
To Be Published
8RJC
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BU of 8rjc by Molmil
Structure of the rabbit 80S ribosome stalled on a 2-TMD rhodopsin intermediate in complex with Sec61-TRAP, open conformation 1
Descriptor: 28S rRNA, 5.8S rRNA, 5S rRNA, ...
Authors:Lewis, A.J.O, Hegde, R.S.
Deposit date:2023-12-20
Release date:2024-01-24
Method:ELECTRON MICROSCOPY (2.90061 Å)
Cite:Structure of the rabbit 80S ribosome stalled on a 2-TMD rhodopsin intermediate in complex with Sec61-TRAP, open conformation 1
To Be Published
6T58
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BU of 6t58 by Molmil
Structure determination of the transactivation domain of p53 in complex with S100A4 using annexin A2 as a crystallization chaperone
Descriptor: CALCIUM ION, Cellular tumor antigen p53,Protein S100-A4,Protein S100-A4,Annexin A2, GLYCEROL
Authors:Ecsedi, P, Gogl, G, Nyitray, L.
Deposit date:2019-10-15
Release date:2020-05-27
Last modified:2024-01-31
Method:X-RAY DIFFRACTION (3.1 Å)
Cite:Structure Determination of the Transactivation Domain of p53 in Complex with S100A4 Using Annexin A2 as a Crystallization Chaperone.
Structure, 28, 2020
4JY1
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BU of 4jy1 by Molmil
CRYSTAL STRUCTURE OF HCV NS5B POLYMERASE IN COMPLEX WITH COMPOUND 5
Descriptor: 3-{ISOPROPYL[(TRANS-4-METHYLCYCLOHEXYL)CARBONYL]AMINO}-5-PHENYLTHIOPHENE-2-CARBOXYLIC ACID, Genome polyprotein
Authors:Coulombe, R.
Deposit date:2013-03-28
Release date:2014-04-23
Last modified:2023-09-20
Method:X-RAY DIFFRACTION (2.6 Å)
Cite:Distinguishing drug binding pockets on proteins by complementary biophysical and biological methods
To be Published
4OLB
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BU of 4olb by Molmil
Crystal Structure of Human Argonaute2 Bound to Tryptophan
Descriptor: 5'-R(P*AP*AP*AP*AP*AP*AP*AP*AP*AP*U)-3', Protein argonaute-2, TRYPTOPHAN
Authors:Schirle, N.T, MacRae, I.J.
Deposit date:2014-01-23
Release date:2014-02-05
Last modified:2023-09-20
Method:X-RAY DIFFRACTION (2.899 Å)
Cite:The crystal structure of human Argonaute2.
Science, 336, 2012
4OLA
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BU of 4ola by Molmil
Crystal Structure of Human Argonaute2
Descriptor: 5'-R(P*AP*AP*AP*AP*AP*AP*AP*AP*AP*U)-3', ISOPROPYL ALCOHOL, PHENOL, ...
Authors:Schirle, N.T, MacRae, I.J.
Deposit date:2014-01-23
Release date:2014-02-05
Last modified:2024-02-28
Method:X-RAY DIFFRACTION (2.3 Å)
Cite:The crystal structure of human Argonaute2.
Science, 336, 2012
7V1B
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BU of 7v1b by Molmil
Crystal structure of Omsk hemorrhagic fever virus NS5 MTase (in complex with SAH)
Descriptor: CITRIC ACID, Core protein, ISOPROPYL ALCOHOL, ...
Authors:Jia, H, Gong, P.
Deposit date:2021-08-04
Release date:2022-06-15
Last modified:2023-11-29
Method:X-RAY DIFFRACTION (1.45 Å)
Cite:Crystal Structures of Flavivirus NS5 Guanylyltransferase Reveal a GMP-Arginine Adduct.
J.Virol., 96, 2022
7V1H
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BU of 7v1h by Molmil
Crystal structure of Omsk hemorrhagic fever virus NS5 MTase (in complex with SAM and m7GTP)
Descriptor: 7-METHYL-GUANOSINE-5'-TRIPHOSPHATE, CITRIC ACID, Core protein, ...
Authors:Jia, H, Gong, P.
Deposit date:2021-08-04
Release date:2022-06-15
Last modified:2023-11-29
Method:X-RAY DIFFRACTION (2 Å)
Cite:Crystal Structures of Flavivirus NS5 Guanylyltransferase Reveal a GMP-Arginine Adduct.
J.Virol., 96, 2022
7V1J
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BU of 7v1j by Molmil
Crystal structure of Omsk hemorrhagic fever virus NS5 MTase (in complex with SAH and m7GpppA)
Descriptor: Core protein, P1-7-METHYLGUANOSINE-P3-ADENOSINE-5',5'-TRIPHOSPHATE, S-ADENOSYL-L-HOMOCYSTEINE
Authors:Jia, H, Gong, P.
Deposit date:2021-08-04
Release date:2022-06-15
Last modified:2023-11-29
Method:X-RAY DIFFRACTION (1.98 Å)
Cite:Crystal Structures of Flavivirus NS5 Guanylyltransferase Reveal a GMP-Arginine Adduct.
J.Virol., 96, 2022
7V1I
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BU of 7v1i by Molmil
Crystal structure of Omsk hemorrhagic fever virus NS5 MTase (with an m7GMP-Arg28 adduct and in complex with SAH)
Descriptor: 7-METHYL-GUANOSINE-5'-TRIPHOSPHATE, Core protein, GLYCEROL, ...
Authors:Jia, H, Gong, P.
Deposit date:2021-08-04
Release date:2022-06-15
Last modified:2023-11-29
Method:X-RAY DIFFRACTION (2.06 Å)
Cite:Crystal Structures of Flavivirus NS5 Guanylyltransferase Reveal a GMP-Arginine Adduct.
J.Virol., 96, 2022
7V1C
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BU of 7v1c by Molmil
Crystal structure of Omsk hemorrhagic fever virus NS5 MTase (in complex with SIN)
Descriptor: Core protein, DI(HYDROXYETHYL)ETHER, GLYCEROL, ...
Authors:Jia, H, Gong, P.
Deposit date:2021-08-04
Release date:2022-06-15
Last modified:2023-11-29
Method:X-RAY DIFFRACTION (1.95 Å)
Cite:Crystal Structures of Flavivirus NS5 Guanylyltransferase Reveal a GMP-Arginine Adduct.
J.Virol., 96, 2022
7V1D
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BU of 7v1d by Molmil
Crystal structure of Omsk hemorrhagic fever virus NS5 MTase (in complex with SAH and GpppA)
Descriptor: Core protein, DI(HYDROXYETHYL)ETHER, GLYCEROL, ...
Authors:Jia, H, Gong, P.
Deposit date:2021-08-04
Release date:2022-06-15
Last modified:2023-11-29
Method:X-RAY DIFFRACTION (1.87 Å)
Cite:Crystal Structures of Flavivirus NS5 Guanylyltransferase Reveal a GMP-Arginine Adduct.
J.Virol., 96, 2022
7V1G
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BU of 7v1g by Molmil
Crystal structure of Omsk hemorrhagic fever virus NS5 MTase (with a GMP-Arg28 adduct and in complex with SAM)
Descriptor: CITRIC ACID, Core protein, GLYCEROL, ...
Authors:Jia, H, Gong, P.
Deposit date:2021-08-04
Release date:2022-06-15
Last modified:2023-11-29
Method:X-RAY DIFFRACTION (1.38 Å)
Cite:Crystal Structures of Flavivirus NS5 Guanylyltransferase Reveal a GMP-Arginine Adduct.
J.Virol., 96, 2022
7V1E
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BU of 7v1e by Molmil
Crystal structure of Omsk hemorrhagic fever virus NS5 MTase (in complex with SAH and m7GpppAmG)
Descriptor: 7-METHYL-GUANOSINE-5'-TRIPHOSPHATE-5'-(2'-O-METHYL)-ADENOSINE, Core protein, GLYCEROL, ...
Authors:Jia, H, Gong, P.
Deposit date:2021-08-04
Release date:2022-06-15
Last modified:2023-11-29
Method:X-RAY DIFFRACTION (1.59 Å)
Cite:Crystal Structures of Flavivirus NS5 Guanylyltransferase Reveal a GMP-Arginine Adduct.
J.Virol., 96, 2022
7V1F
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BU of 7v1f by Molmil
Crystal structure of Omsk hemorrhagic fever virus NS5 MTase (in complex with SAM and GTP)
Descriptor: Core protein, GLYCEROL, GUANOSINE-5'-TRIPHOSPHATE, ...
Authors:Jia, H, Gong, P.
Deposit date:2021-08-04
Release date:2022-06-15
Last modified:2023-11-29
Method:X-RAY DIFFRACTION (2 Å)
Cite:Crystal Structures of Flavivirus NS5 Guanylyltransferase Reveal a GMP-Arginine Adduct.
J.Virol., 96, 2022
8FVI
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BU of 8fvi by Molmil
Human APOBEC3H bound to HIV-1 Vif in complex with CBF-beta, ELOB, ELOC, and CUL5
Descriptor: Core-binding factor subunit beta, Cullin 5, DNA dC->dU-editing enzyme APOBEC-3H, ...
Authors:Ito, F, Alvarez-Cabrera, A.L, Zhou, Z.H, Chen, X.S.
Deposit date:2023-01-19
Release date:2023-09-06
Last modified:2024-05-01
Method:ELECTRON MICROSCOPY (3.24 Å)
Cite:Structural basis of HIV-1 Vif-mediated E3 ligase targeting of host APOBEC3H.
Nat Commun, 14, 2023
6ANQ
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BU of 6anq by Molmil
STRUCTURE OF HIV-1 REVERSE TRANSCRIPTASE (RT) TERNARY COMPLEX WITH A DOUBLE STRANDED DNA AND AN INCOMING D4TTP AT PH 8.5
Descriptor: 2',3'-DEHYDRO-2',3'-DEOXY-THYMIDINE 5'-TRIPHOSPHATE, DNA PRIMER (5'- D(*AP*CP*AP*GP*TP*CP*CP*CP*TP*GP*TP*TP*CP*GP*GP*GP*CP*GP*CP*CP*GP)-3'), DNA TEMPLATE (5'- D(*AP*TP*GP*AP*AP*CP*GP*GP*CP*GP*CP*CP*CP*GP*AP*AP*CP*AP*GP*GP*GP*AP*CP*TP*GP*TP*G)-3'), ...
Authors:Martinez, S.E, Das, K, Arnold, E.
Deposit date:2017-08-14
Release date:2018-08-15
Last modified:2023-10-04
Method:X-RAY DIFFRACTION (2.586 Å)
Cite:Structure of HIV-1 reverse transcriptase/d4TTP complex: Novel DNA cross-linking site and pH-dependent conformational changes.
Protein Sci., 28, 2019

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數據於2024-07-24公開中

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