6P94
Human APE1 C65A AP-endonuclease product complex
Summary for 6P94
Entry DOI | 10.2210/pdb6p94/pdb |
Related | 6P93 |
Descriptor | DNA-(apurinic or apyrimidinic site) lyase, DNA (5'-D(P*(3DR)P*CP*GP*AP*CP*GP*GP*AP*TP*CP*C)-3'), DNA (5'-D(*GP*CP*TP*GP*AP*TP*GP*CP*GP*C)-3'), ... (9 entities in total) |
Functional Keywords | ape1, nuclease, dna repair, dna binding protein, lyase-dna complex, lyase/dna |
Biological source | Homo sapiens (Human) More |
Total number of polymer chains | 5 |
Total formula weight | 75463.36 |
Authors | Whitaker, A.W.,Stark, W.J.,Freudenthal, B.D. (deposition date: 2019-06-09, release date: 2020-01-01, Last modification date: 2023-10-11) |
Primary citation | McNeill, D.R.,Whitaker, A.M.,Stark, W.J.,Illuzzi, J.L.,McKinnon, P.J.,Freudenthal, B.D.,Wilson, D.M. Functions of the major abasic endonuclease (APE1) in cell viability and genotoxin resistance. Mutagenesis, 35:27-38, 2020 Cited by PubMed: 31816044DOI: 10.1093/mutage/gez046 PDB entries with the same primary citation |
Experimental method | X-RAY DIFFRACTION (2.09 Å) |
Structure validation
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