6E21
 
 | | Joint X-ray/neutron structure of PKAc with products Sr2-ADP and phosphorylated peptide SP20 | | Descriptor: | ADENOSINE-5'-DIPHOSPHATE, STRONTIUM ION, cAMP-dependent protein kinase catalytic subunit alpha, ... | | Authors: | Kovalevsky, A, Gerlits, O.O, Taylor, S. | | Deposit date: | 2018-07-10 | | Release date: | 2019-04-03 | | Last modified: | 2023-10-25 | | Method: | NEUTRON DIFFRACTION (2 Å), X-RAY DIFFRACTION | | Cite: | Zooming in on protons: Neutron structure of protein kinase A trapped in a product complex.
Sci Adv, 5, 2019
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6EDE
 | | tRNA 2'-phosphotransferase | | Descriptor: | Probable RNA 2'-phosphotransferase, [[(2~{R},3~{S},4~{R},5~{R})-5-(6-aminopurin-9-yl)-3,4-bis(oxidanyl)oxolan-2-yl]methoxy-oxidanyl-phosphoryl] [(2~{R},3~{S},4~{R},5~{R})-3,4-bis(oxidanyl)-5-phosphonooxy-oxolan-2-yl]methyl hydrogen phosphate | | Authors: | Shuman, S, Goldgur, Y, Banerjee, A. | | Deposit date: | 2018-08-09 | | Release date: | 2019-03-20 | | Last modified: | 2023-10-11 | | Method: | X-RAY DIFFRACTION (1.553 Å) | | Cite: | Structure of tRNA splicing enzyme Tpt1 illuminates the mechanism of RNA 2'-PO4recognition and ADP-ribosylation.
Nat Commun, 10, 2019
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4EDN
 | | Crystal structure of beta-parvin CH2 domain in complex with paxillin LD1 motif | | Descriptor: | Beta-parvin, Paxillin, SULFATE ION | | Authors: | Stiegler, A.L, Draheim, K.M, Li, X, Chayen, N.E, Calderwood, D.A, Boggon, T.J. | | Deposit date: | 2012-03-27 | | Release date: | 2012-08-08 | | Last modified: | 2013-06-19 | | Method: | X-RAY DIFFRACTION (2.9 Å) | | Cite: | Structural basis for paxillin binding and focal adhesion targeting of beta-parvin.
J.Biol.Chem., 287, 2012
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2NWM
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6FJO
 | | Adenovirus species 26 knob protein, very high resolution | | Descriptor: | Fiber, GLUTAMIC ACID, GLYCEROL, ... | | Authors: | Rizkallah, P.J, Parker, A.L, Baker, A.T. | | Deposit date: | 2018-01-22 | | Release date: | 2019-02-06 | | Last modified: | 2024-01-17 | | Method: | X-RAY DIFFRACTION (1.17 Å) | | Cite: | Human adenovirus type 26 uses sialic acid-bearing glycans as a primary cell entry receptor.
Sci Adv, 5, 2019
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6ERU
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6V6M
 | | Crystal structure of an inactive state of GMPPNP-bound RhoA | | Descriptor: | 1,4-DIETHYLENE DIOXIDE, MAGNESIUM ION, PHOSPHOAMINOPHOSPHONIC ACID-GUANYLATE ESTER, ... | | Authors: | Lin, Y, Zheng, Y. | | Deposit date: | 2019-12-05 | | Release date: | 2020-12-09 | | Last modified: | 2023-10-11 | | Method: | X-RAY DIFFRACTION (1.39 Å) | | Cite: | Structure of an inactive conformation of GTP-bound RhoA GTPase.
Structure, 29, 2021
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6V6U
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6EGW
 | | Crystal Structure of the Protein-Kinase A catalytic subunit from Criteculus Griseus in complex with compounds RKp017 and RKp117 | | Descriptor: | [2-[(4-isoquinolin-5-ylsulfonyl-1,4-diazepan-1-yl)methyl]phenyl]boronic acid, alpha-D-ribofuranose, cAMP-dependent protein kinase catalytic subunit alpha, ... | | Authors: | Mueller, J.M, Heine, A, Klebe, G. | | Deposit date: | 2017-09-12 | | Release date: | 2018-10-10 | | Last modified: | 2020-07-29 | | Method: | X-RAY DIFFRACTION (1.74 Å) | | Cite: | Conceptional Design of Self-Assembling Bisubstrate-like Inhibitors of Protein Kinase A Resulting in a Boronic Acid Glutamate Linkage
Acs Omega, 2019
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6EM7
 | | Crystal Structure of the Protein-Kinase A catalytic subunit from Criteculus Griseus in complex with compounds RKp120 and ADP | | Descriptor: | (4S)-2-METHYL-2,4-PENTANEDIOL, ADENOSINE-5'-DIPHOSPHATE, UPF0418 protein FAM164A, ... | | Authors: | Mueller, J.M, Heine, A, Klebe, G. | | Deposit date: | 2017-10-01 | | Release date: | 2018-10-10 | | Last modified: | 2020-07-29 | | Method: | X-RAY DIFFRACTION (1.238 Å) | | Cite: | Conceptional Design of Self-Assembling Bisubstrate-like Inhibitors of Protein Kinase A Resulting in a Boronic Acid Glutamate Linkage
Acs Omega, 2019
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6ERW
 | | Crystal Structure of the Protein-Kinase A catalytic subunit from Criteculus Griseus in complex with compounds RKp013 and Fasudil | | Descriptor: | (4S)-2-METHYL-2,4-PENTANEDIOL, 5-(1,4-DIAZEPAN-1-SULFONYL)ISOQUINOLINE, UPF0418 protein FAM164A, ... | | Authors: | Mueller, J.M, Heine, A, Klebe, G. | | Deposit date: | 2017-10-19 | | Release date: | 2018-10-31 | | Last modified: | 2019-05-15 | | Method: | X-RAY DIFFRACTION (1.89 Å) | | Cite: | Conceptional Design of Self-Assembling Bisubstrate-like Inhibitors of Protein Kinase A Resulting in a Boronic Acid Glutamate Linkage
Acs Omega, 2019
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6EH3
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6ESA
 | | Crystal Structure of the Protein-Kinase A catalytic subunit from Criteculus Griseus in complex with compounds RKp120 and AMP | | Descriptor: | (4S)-2-METHYL-2,4-PENTANEDIOL, ADENOSINE MONOPHOSPHATE, beta-D-ribopyranose, ... | | Authors: | Mueller, J.M, Heine, A, Klebe, G. | | Deposit date: | 2017-10-19 | | Release date: | 2018-10-31 | | Last modified: | 2020-07-29 | | Method: | X-RAY DIFFRACTION (1.307 Å) | | Cite: | Conceptional Design of Self-Assembling Bisubstrate-like Inhibitors of Protein Kinase A Resulting in a Boronic Acid Glutamate Linkage
Acs Omega, 2019
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4EDM
 | | Crystal structure of beta-parvin CH2 domain | | Descriptor: | 1,2-ETHANEDIOL, Beta-parvin | | Authors: | Stiegler, A.L, Draheim, K.M, Li, X, Chayen, N.E, Calderwood, D.A, Boggon, T.J. | | Deposit date: | 2012-03-27 | | Release date: | 2012-08-08 | | Last modified: | 2024-02-28 | | Method: | X-RAY DIFFRACTION (2 Å) | | Cite: | Structural basis for paxillin binding and focal adhesion targeting of beta-parvin.
J.Biol.Chem., 287, 2012
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2OZL
 | | Human pyruvate dehydrogenase S264E variant | | Descriptor: | MAGNESIUM ION, POTASSIUM ION, Pyruvate dehydrogenase E1 component alpha subunit, ... | | Authors: | Ciszak, E.M, Dominiak, P.M, Patel, M.S, Korotchkina, L.G. | | Deposit date: | 2007-02-26 | | Release date: | 2007-05-22 | | Last modified: | 2023-08-30 | | Method: | X-RAY DIFFRACTION (1.9 Å) | | Cite: | Phosphorylation of Serine 264 Impedes Active Site Accessibility in the E1 Component of the Human Pyruvate Dehydrogenase Multienzyme Complex
Biochemistry, 46, 2007
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2PN9
 | | NMR structure of a kissing complex formed between the TAR RNA element of HIV-1 and a LNA modified aptamer | | Descriptor: | 5'-R(*GP*GP*AP*GP*CP*CP*UP*GP*GP*GP*AP*GP*CP*UP*CP*C)-3', RNA 16-mer with locked residues 9-10 | | Authors: | Lebars, I, Richard, T, Di Primo, C, Toulme, J.-J. | | Deposit date: | 2007-04-24 | | Release date: | 2007-10-30 | | Last modified: | 2024-05-01 | | Method: | SOLUTION NMR | | Cite: | NMR structure of a kissing complex formed between the TAR RNA element of HIV-1 and a LNA-modified aptamer
Nucleic Acids Res., 35, 2007
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2OOM
 | | NMR structure of a kissing complex formed between the TAR RNA element of HIV-1 and a LNA/RNA aptamer | | Descriptor: | RNA 16-mer, TAR RNA element of HIV-1 | | Authors: | Lebars, I, Richard, T, Di Primo, C, Toulme, J.J. | | Deposit date: | 2007-01-26 | | Release date: | 2008-01-29 | | Last modified: | 2023-12-27 | | Method: | SOLUTION NMR | | Cite: | NMR structure of a kissing complex formed between the TAR RNA element of HIV-1 and a LNA-modified aptamer
Nucleic Acids Res., 35, 2007
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2Q8P
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2N8U
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2Q7Q
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2QCS
 | | A complex structure between the Catalytic and Regulatory subunit of Protein Kinase A that represents the inhibited state | | Descriptor: | ACETATE ION, GLYCEROL, MANGANESE (II) ION, ... | | Authors: | Kim, C, Cheng, C.Y, Saldanha, A.S, Taylor, S.S. | | Deposit date: | 2007-06-19 | | Release date: | 2007-11-06 | | Last modified: | 2023-08-30 | | Method: | X-RAY DIFFRACTION (2.2 Å) | | Cite: | PKA-I holoenzyme structure reveals a mechanism for cAMP-dependent activation.
Cell(Cambridge,Mass.), 130, 2007
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2MYH
 | | Omega-Tbo-IT1: selective inhibitor of insect calcium channels isolated from Tibellus oblongus spider venom | | Descriptor: | Omega-Tbo-IT1 toxin | | Authors: | Altukhov, D, Bozin, T, Bocharov, E, Kozlov, S, Mikov, A. | | Deposit date: | 2015-01-23 | | Release date: | 2015-12-09 | | Method: | SOLUTION NMR | | Cite: | omega-Tbo-IT1-New Inhibitor of Insect Calcium Channels Isolated from Spider Venom.
Sci Rep, 5, 2015
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2N8S
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2QVF
 | | mouse E-cadherin domains 1,2 | | Descriptor: | CALCIUM ION, Epithelial-cadherin (E-cadherin) (Uvomorulin) (Cadherin-1) (ARC-1) (CD324 antigen) | | Authors: | Carroll, K.J. | | Deposit date: | 2007-08-08 | | Release date: | 2008-08-12 | | Last modified: | 2023-08-30 | | Method: | X-RAY DIFFRACTION (2.4 Å) | | Cite: | E-cadherin domains 1,2
To be Published
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7OPX
 | | CryoEM structure of human enterovirus 70 native virion | | Descriptor: | Capsid protein VP1, Capsid protein VP2, Capsid protein VP3, ... | | Authors: | Fuzik, T, Plevka, P, Moravcova, J. | | Deposit date: | 2021-06-02 | | Release date: | 2022-06-22 | | Last modified: | 2024-07-17 | | Method: | ELECTRON MICROSCOPY (2.63 Å) | | Cite: | Structure of Human Enterovirus 70 and Its Inhibition by Capsid-Binding Compounds.
J.Virol., 96, 2022
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