6EH3

Crystal Structure of the Protein-Kinase A catalytic subunit from Criteculus Griseus in complex with compounds RKp120 and RKp190

Summary for 6EH3

• Entry DOI: 10.2210/pdb6eh3/pdb
• Descriptor: cAMP-dependent protein kinase catalytic subunit alpha, cAMP-dependent protein kinase inhibitor, ~{N}-[2-[(phenylmethyl)amino]ethyl]isoquinoline-5-sulfonamide, ... (4 entities in total)
• Functional Keywords: complex, peptidic ligand, transferase
• Biological source: Cricetulus griseus (Chinese hamster); More
• Total number of polymer chains: 2
• Total formula weight: 43481.33

Authors

Mueller, J.M.,Heine, A.,Klebe, G. (deposition date: 2017-09-12, release date: 2018-10-10, Last modification date: 2024-11-20)

• Primary citation: Mueller, J.M.,Kirschner, R.,Heine, A.,Geyer, A.,Klebe, G.; Crystal Structure of the Protein-Kinase A catalytic subunit from Criteculus Griseus in complex with compounds RKp120 and RKp190; To be published,

Experimental method

X-RAY DIFFRACTION (1.95 Å)