4EDN
Crystal structure of beta-parvin CH2 domain in complex with paxillin LD1 motif
Summary for 4EDN
Entry DOI | 10.2210/pdb4edn/pdb |
Related | 4EDL 4EDM |
Descriptor | Beta-parvin, Paxillin, SULFATE ION, ... (4 entities in total) |
Functional Keywords | calponin homology domain, protein-protein interaction, ld motif, integrin signaling, focal adhesion, adaptor protein, paxillin, integrin linked kinase, signaling protein-cell adhesion complex, signaling protein/cell adhesion |
Biological source | Homo sapiens (human) More |
Cellular location | Cell junction, focal adhesion: Q9HBI1 Cytoplasm, cytoskeleton: P49023 |
Total number of polymer chains | 17 |
Total formula weight | 169222.48 |
Authors | Stiegler, A.L.,Draheim, K.M.,Li, X.,Chayen, N.E.,Calderwood, D.A.,Boggon, T.J. (deposition date: 2012-03-27, release date: 2012-08-08, Last modification date: 2013-06-19) |
Primary citation | Stiegler, A.L.,Draheim, K.M.,Li, X.,Chayen, N.E.,Calderwood, D.A.,Boggon, T.J. Structural basis for paxillin binding and focal adhesion targeting of beta-parvin. J.Biol.Chem., 287:32566-32577, 2012 Cited by PubMed: 22869380DOI: 10.1074/jbc.M112.367342 PDB entries with the same primary citation |
Experimental method | X-RAY DIFFRACTION (2.9 Å) |
Structure validation
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