6EM7
Crystal Structure of the Protein-Kinase A catalytic subunit from Criteculus Griseus in complex with compounds RKp120 and ADP
Summary for 6EM7
Entry DOI | 10.2210/pdb6em7/pdb |
Descriptor | cAMP-dependent protein kinase catalytic subunit alpha, UPF0418 protein FAM164A, (4S)-2-METHYL-2,4-PENTANEDIOL, ... (6 entities in total) |
Functional Keywords | complex, peptidic ligand, transferase |
Biological source | Cricetulus griseus (Chinese hamster) More |
Total number of polymer chains | 2 |
Total formula weight | 43873.60 |
Authors | Mueller, J.M.,Heine, A.,Klebe, G. (deposition date: 2017-10-01, release date: 2018-10-10, Last modification date: 2020-07-29) |
Primary citation | Mueller, J.M.,Kirschner, R.,Geyer, A.,Klebe, G. Conceptional Design of Self-Assembling Bisubstrate-like Inhibitors of Protein Kinase A Resulting in a Boronic Acid Glutamate Linkage Acs Omega, 2019 Cited by DOI: 10.1021/acsomega.8b02364PDB entries with the same primary citation |
Experimental method | X-RAY DIFFRACTION (1.238 Å) |
Structure validation
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