6EM7

Crystal Structure of the Protein-Kinase A catalytic subunit from Criteculus Griseus in complex with compounds RKp120 and ADP

Summary for 6EM7

Entry DOI	10.2210/pdb6em7/pdb
Descriptor	cAMP-dependent protein kinase catalytic subunit alpha, UPF0418 protein FAM164A, (4S)-2-METHYL-2,4-PENTANEDIOL, ... (6 entities in total)
Functional Keywords	complex, peptidic ligand, transferase
Biological source	Cricetulus griseus (Chinese hamster) More
Total number of polymer chains	2
Total formula weight	43873.60
Authors	Mueller, J.M.,Heine, A.,Klebe, G. (deposition date: 2017-10-01, release date: 2018-10-10, Last modification date: 2024-11-13)
Primary citation	Mueller, J.M.,Kirschner, R.,Geyer, A.,Klebe, G. Conceptional Design of Self-Assembling Bisubstrate-like Inhibitors of Protein Kinase A Resulting in a Boronic Acid Glutamate Linkage Acs Omega, 2019 Cited by DOI: 10.1021/acsomega.8b02364 PDB entries with the same primary citation
Experimental method	X-RAY DIFFRACTION (1.238 Å)

Structure validation