6EM7
Crystal Structure of the Protein-Kinase A catalytic subunit from Criteculus Griseus in complex with compounds RKp120 and ADP
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A (A) | cAMP-dependent protein kinase catalytic subunit alpha | polymer | 353 | 41113.8 | 1 | UniProt (P25321) Pfam (PF00069) | Cricetulus griseus (Chinese hamster) | PKA C-alpha |
| 2 | B (D) | UPF0418 protein FAM164A | polymer | 18 | 1946.2 | 1 | UniProt (G3HK48) | Cricetulus griseus | |
| 3 | C, D (A) | (4S)-2-METHYL-2,4-PENTANEDIOL | non-polymer | 118.2 | 2 | Chemie (MPD) | |||
| 4 | E (A) | ADENOSINE-5'-DIPHOSPHATE | non-polymer | 427.2 | 1 | Chemie (ADP) | |||
| 5 | F (D) | beta-D-ribopyranose | non-polymer | 150.1 | 1 | Chemie (RIP) | |||
| 6 | G, H (A, D) | water | water | 18.0 | 335 | Chemie (HOH) |
Sequence modifications
A: 0 - 350 (UniProt: P25321)
D: 6 - 23 (UniProt: G3HK48)
| PDB | External Database | Details |
|---|---|---|
| Gly -2 | - | expression tag |
| His -1 | - | expression tag |
| PDB | External Database | Details |
|---|---|---|
| Ser 21 | Asn 21 | engineered mutation |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 2 |
| Total formula weight | 43059.9 | |
| Non-Polymers* | Number of molecules | 4 |
| Total formula weight | 813.7 | |
| All* | Total formula weight | 43873.6 |
