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7Q4Y
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BU of 7q4y by Molmil
human Gid4 bound to a Gly/N-peptide
Descriptor: Glucose-induced degradation protein 4 homolog
Authors:Sherpa, D, Chrustowicz, J, Prabu, J.R, Schulman, B.A.
Deposit date:2021-11-02
Release date:2022-03-09
Last modified:2024-01-31
Method:X-RAY DIFFRACTION (3.08 Å)
Cite:Multifaceted N-Degron Recognition and Ubiquitylation by GID/CTLH E3 Ligases.
J.Mol.Biol., 434, 2022
7Q50
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BU of 7q50 by Molmil
human Gid4 bound to a Phe/N-peptide
Descriptor: FDVSWFMG peptide, Glucose-induced degradation protein 4 homolog
Authors:Chrustowicz, J, Sherpa, D, Loke, M.S, Prabu, J.R, Schulman, B.A.
Deposit date:2021-11-02
Release date:2022-03-02
Last modified:2024-01-31
Method:X-RAY DIFFRACTION (3.16 Å)
Cite:Multifaceted N-Degron Recognition and Ubiquitylation by GID/CTLH E3 Ligases.
J.Mol.Biol., 434, 2022
3PCG
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BU of 3pcg by Molmil
STRUCTURE OF PROTOCATECHUATE 3,4-DIOXYGENASE COMPLEXED WITH THE INHIBITOR 4-HYDROXYPHENYLACETATE
Descriptor: 4-HYDROXYPHENYLACETATE, BETA-MERCAPTOETHANOL, FE (III) ION, ...
Authors:Elango, N, Orville, A.M, Lipscomb, J.D, Ohlendorf, D.H.
Deposit date:1997-04-29
Release date:1998-04-29
Last modified:2023-09-27
Method:X-RAY DIFFRACTION (1.96 Å)
Cite:Structures of competitive inhibitor complexes of protocatechuate 3,4-dioxygenase: multiple exogenous ligand binding orientations within the active site.
Biochemistry, 36, 1997
3PCE
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BU of 3pce by Molmil
STRUCTURE OF PROTOCATECHUATE 3,4-DIOXYGENASE COMPLEXED WITH 3-HYDROXYPHENYLACETATE
Descriptor: 3-HYDROXYPHENYLACETATE, BETA-MERCAPTOETHANOL, FE (III) ION, ...
Authors:Elango, N, Orville, A.M, Lipscomb, J.D, Ohlendorf, D.H.
Deposit date:1997-04-29
Release date:1998-04-29
Last modified:2023-09-27
Method:X-RAY DIFFRACTION (2.06 Å)
Cite:Structures of competitive inhibitor complexes of protocatechuate 3,4-dioxygenase: multiple exogenous ligand binding orientations within the active site.
Biochemistry, 36, 1997
3PCC
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BU of 3pcc by Molmil
STRUCTURE OF PROTOCATECHUATE 3,4-DIOXYGENASE COMPLEXED WITH 4-HYDROXYBENZOATE
Descriptor: BETA-MERCAPTOETHANOL, FE (III) ION, P-HYDROXYBENZOIC ACID, ...
Authors:Elango, N, Orville, A.M, Lipscomb, J.D, Ohlendorf, D.H.
Deposit date:1997-04-29
Release date:1998-04-29
Last modified:2023-09-27
Method:X-RAY DIFFRACTION (1.98 Å)
Cite:Structures of competitive inhibitor complexes of protocatechuate 3,4-dioxygenase: multiple exogenous ligand binding orientations within the active site.
Biochemistry, 36, 1997
7TZG
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BU of 7tzg by Molmil
Structure of human LAG3 in complex with antibody single-chain variable fragment
Descriptor: 2-acetamido-2-deoxy-beta-D-glucopyranose, Lymphocyte activation gene 3 protein, scFvF7
Authors:Ming, Q, Tran, T.H, Luca, V.C.
Deposit date:2022-02-15
Release date:2022-05-11
Last modified:2023-10-18
Method:X-RAY DIFFRACTION (3.71 Å)
Cite:LAG3 ectodomain structure reveals functional interfaces for ligand and antibody recognition.
Nat.Immunol., 23, 2022
7TZH
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BU of 7tzh by Molmil
Structure of human LAG3 domains 3-4 in complex with antibody single chain-variable fragment
Descriptor: 2-acetamido-2-deoxy-beta-D-glucopyranose, Lymphocyte activation gene 3 protein, scFvF7
Authors:Ming, Q, Tran, T.H, Luca, V.C.
Deposit date:2022-02-15
Release date:2022-05-11
Last modified:2023-10-18
Method:X-RAY DIFFRACTION (2.43 Å)
Cite:LAG3 ectodomain structure reveals functional interfaces for ligand and antibody recognition.
Nat.Immunol., 23, 2022
7TZ2
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BU of 7tz2 by Molmil
Structure of human Fibrinogen-like protein 1
Descriptor: CALCIUM ION, Fibrinogen-like protein 1
Authors:Ming, Q, Tran, T.H, Luca, V.C.
Deposit date:2022-02-15
Release date:2022-05-11
Last modified:2023-10-18
Method:X-RAY DIFFRACTION (2.55 Å)
Cite:LAG3 ectodomain structure reveals functional interfaces for ligand and antibody recognition.
Nat.Immunol., 23, 2022
7TZE
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BU of 7tze by Molmil
Structure of murine LAG3 domains 1-2
Descriptor: 1,2-ETHANEDIOL, 2-acetamido-2-deoxy-beta-D-glucopyranose, Lymphocyte activation gene 3 protein
Authors:Ming, Q, Tran, T.H, Luca, V.C.
Deposit date:2022-02-15
Release date:2022-05-11
Last modified:2023-10-18
Method:X-RAY DIFFRACTION (2.12 Å)
Cite:LAG3 ectodomain structure reveals functional interfaces for ligand and antibody recognition.
Nat.Immunol., 23, 2022
4NXR
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BU of 4nxr by Molmil
Crystal Structure of T-cell Lymphoma Invasion and Metastasis-1 PDZ Domain Quadruple Mutant (QM) in Complex With Neurexin-1 Peptide
Descriptor: 4-(2-HYDROXYETHYL)-1-PIPERAZINE ETHANESULFONIC ACID, 5-(DIMETHYLAMINO)-1-NAPHTHALENESULFONIC ACID(DANSYL ACID), Neurexin-2-beta Peptide, ...
Authors:Liu, X, Speckhard, D.C, Shepherd, T.R, Hengel, S.R, Fuentes, E.J.
Deposit date:2013-12-09
Release date:2015-05-13
Last modified:2023-09-20
Method:X-RAY DIFFRACTION (1.9 Å)
Cite:Distinct Roles for Conformational Dynamics in Protein-Ligand Interactions.
Structure, 24, 2016
7SUM
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BU of 7sum by Molmil
Crystal structure of human ligase I with nick duplexes containing cognate A:T
Descriptor: ADENOSINE MONOPHOSPHATE, DNA ligase 1, DNA(5'-*GP*CP*TP*GP*AP*TP*GP*CP*GP*TP*A-3'), ...
Authors:Tang, Q, Gulkis, M, McKenna, R, Caglayan, M.
Deposit date:2021-11-17
Release date:2022-07-13
Last modified:2023-10-18
Method:X-RAY DIFFRACTION (2.9 Å)
Cite:Structures of LIG1 that engage with mutagenic mismatches inserted by pol beta in base excision repair.
Nat Commun, 13, 2022
7GSB
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BU of 7gsb by Molmil
PanDDA Analysis group deposition -- Crystal structure of PTP1B in complex with FMOPL000438a
Descriptor: 1-(4-benzylpiperidin-1-yl)-2-methylpropan-1-one, 2-AMINO-2-HYDROXYMETHYL-PROPANE-1,3-DIOL, Tyrosine-protein phosphatase non-receptor type 1
Authors:Mehlman, T, Ginn, H.M, Keedy, D.A.
Deposit date:2024-01-03
Release date:2024-01-24
Last modified:2024-04-24
Method:X-RAY DIFFRACTION (1.72 Å)
Cite:An expanded view of ligandability in the allosteric enzyme PTP1B from computational reanalysis of large-scale crystallographic data.
Biorxiv, 2024
2AST
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BU of 2ast by Molmil
Crystal structure of Skp1-Skp2-Cks1 in complex with a p27 peptide
Descriptor: BENZAMIDINE, Cyclin-dependent kinase inhibitor 1B, Cyclin-dependent kinases regulatory subunit 1, ...
Authors:Hao, B, Zhang, N, Schulman, B.A, Wu, G, Pagano, M, Pavletich, N.P.
Deposit date:2005-08-24
Release date:2005-10-18
Last modified:2023-08-23
Method:X-RAY DIFFRACTION (2.3 Å)
Cite:Structural Basis of the Cks1-Dependent Recognition of p27(Kip1) by the SCF(Skp2) Ubiquitin Ligase.
Mol.Cell, 20, 2005
8HPZ
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BU of 8hpz by Molmil
Crystal structure of the MlaD domain of the MlaD protein from Escherichia coli (Form I)
Descriptor: 1,2-ETHANEDIOL, CARBON DIOXIDE, Intermembrane phospholipid transport system binding protein MlaD
Authors:Dutta, A, Kanaujia, S.P.
Deposit date:2022-12-13
Release date:2024-01-10
Last modified:2024-05-15
Method:X-RAY DIFFRACTION (2.3 Å)
Cite:The Structural Features of MlaD Illuminate its Unique Ligand-Transporting Mechanism and Ancestry.
Protein J., 43, 2024
8HQ9
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BU of 8hq9 by Molmil
Crystal structure of the MlaD domain of the MlaD protein from Escherichia coli (Form II)
Descriptor: CARBON DIOXIDE, Intermembrane phospholipid transport system binding protein MlaD, MAGNESIUM ION
Authors:Dutta, A, Kanaujia, S.P.
Deposit date:2022-12-13
Release date:2024-01-10
Last modified:2024-05-15
Method:X-RAY DIFFRACTION (2.7 Å)
Cite:The Structural Features of MlaD Illuminate its Unique Ligand-Transporting Mechanism and Ancestry.
Protein J., 43, 2024
8HQA
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BU of 8hqa by Molmil
Crystal structure of the ectodomain of the MlaD protein from Escherichia coli in the resting state
Descriptor: Intermembrane phospholipid transport system binding protein MlaD
Authors:Dutta, A, Kanaujia, S.P.
Deposit date:2022-12-13
Release date:2024-01-10
Last modified:2024-05-15
Method:X-RAY DIFFRACTION (3.2 Å)
Cite:The Structural Features of MlaD Illuminate its Unique Ligand-Transporting Mechanism and Ancestry.
Protein J., 43, 2024
7GTF
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BU of 7gtf by Molmil
PanDDA Analysis group deposition -- Crystal structure of PTP1B in complex with XST00000754b
Descriptor: 1,2-benzoxazol-3-ol, 2-AMINO-2-HYDROXYMETHYL-PROPANE-1,3-DIOL, Tyrosine-protein phosphatase non-receptor type 1
Authors:Mehlman, T, Ginn, H.M, Keedy, D.A.
Deposit date:2024-01-03
Release date:2024-01-24
Last modified:2024-04-24
Method:X-RAY DIFFRACTION (1.97 Å)
Cite:An expanded view of ligandability in the allosteric enzyme PTP1B from computational reanalysis of large-scale crystallographic data.
Biorxiv, 2024
7GSQ
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BU of 7gsq by Molmil
PanDDA Analysis group deposition -- Crystal structure of PTP1B in complex with FMOMB000149a
Descriptor: 2-AMINO-2-HYDROXYMETHYL-PROPANE-1,3-DIOL, N-[(4-chlorophenyl)methyl]methanesulfonamide, Tyrosine-protein phosphatase non-receptor type 1
Authors:Mehlman, T, Ginn, H.M, Keedy, D.A.
Deposit date:2024-01-03
Release date:2024-01-24
Last modified:2024-04-24
Method:X-RAY DIFFRACTION (1.73 Å)
Cite:An expanded view of ligandability in the allosteric enzyme PTP1B from computational reanalysis of large-scale crystallographic data.
Biorxiv, 2024
7GTD
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BU of 7gtd by Molmil
PanDDA Analysis group deposition -- Crystal structure of PTP1B in complex with FMOMB000110a
Descriptor: 2-AMINO-2-HYDROXYMETHYL-PROPANE-1,3-DIOL, N-[2-(4-chlorophenyl)ethyl]hydrazinecarbothioamide, Tyrosine-protein phosphatase non-receptor type 1
Authors:Mehlman, T, Ginn, H.M, Keedy, D.A.
Deposit date:2024-01-03
Release date:2024-01-24
Last modified:2024-04-24
Method:X-RAY DIFFRACTION (1.91 Å)
Cite:An expanded view of ligandability in the allosteric enzyme PTP1B from computational reanalysis of large-scale crystallographic data.
Biorxiv, 2024
7GSU
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BU of 7gsu by Molmil
PanDDA Analysis group deposition -- Crystal structure of PTP1B in complex with FMOPL000382a
Descriptor: 2-AMINO-2-HYDROXYMETHYL-PROPANE-1,3-DIOL, 2-[(morpholin-4-yl)methyl]phenol, Tyrosine-protein phosphatase non-receptor type 1
Authors:Mehlman, T, Ginn, H.M, Keedy, D.A.
Deposit date:2024-01-03
Release date:2024-01-24
Last modified:2024-04-24
Method:X-RAY DIFFRACTION (1.65 Å)
Cite:An expanded view of ligandability in the allosteric enzyme PTP1B from computational reanalysis of large-scale crystallographic data.
Biorxiv, 2024
7GSK
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BU of 7gsk by Molmil
PanDDA Analysis group deposition -- Crystal structure of PTP1B in complex with FMOPL000279a
Descriptor: 1-(diphenylmethyl)azetidin-3-ol, 2-AMINO-2-HYDROXYMETHYL-PROPANE-1,3-DIOL, Tyrosine-protein phosphatase non-receptor type 1
Authors:Mehlman, T, Ginn, H.M, Keedy, D.A.
Deposit date:2024-01-03
Release date:2024-01-24
Last modified:2024-04-24
Method:X-RAY DIFFRACTION (1.84 Å)
Cite:An expanded view of ligandability in the allosteric enzyme PTP1B from computational reanalysis of large-scale crystallographic data.
Biorxiv, 2024
7GTO
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BU of 7gto by Molmil
PanDDA Analysis group deposition -- Crystal structure of PTP1B in complex with FMOOA000602a
Descriptor: (6aR,8R,12R,12aS)-5-methyl-5,6a,7,10,11,12a-hexahydro-6H,9H-pyrazolo[1',2':1,2]pyrazolo[4,3-c]quinolin-9-one, 2-AMINO-2-HYDROXYMETHYL-PROPANE-1,3-DIOL, Tyrosine-protein phosphatase non-receptor type 1
Authors:Mehlman, T, Ginn, H.M, Keedy, D.A.
Deposit date:2024-01-03
Release date:2024-01-24
Last modified:2024-04-24
Method:X-RAY DIFFRACTION (1.65 Å)
Cite:An expanded view of ligandability in the allosteric enzyme PTP1B from computational reanalysis of large-scale crystallographic data.
Biorxiv, 2024
7GSY
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BU of 7gsy by Molmil
PanDDA Analysis group deposition -- Crystal structure of PTP1B in complex with FMSOA001175b
Descriptor: 2-AMINO-2-HYDROXYMETHYL-PROPANE-1,3-DIOL, 4-[(pyridin-2-yl)oxy]benzonitrile, Tyrosine-protein phosphatase non-receptor type 1
Authors:Mehlman, T, Ginn, H.M, Keedy, D.A.
Deposit date:2024-01-03
Release date:2024-01-24
Last modified:2024-04-24
Method:X-RAY DIFFRACTION (1.97 Å)
Cite:An expanded view of ligandability in the allosteric enzyme PTP1B from computational reanalysis of large-scale crystallographic data.
Biorxiv, 2024
7GTR
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BU of 7gtr by Molmil
PanDDA Analysis group deposition -- Crystal structure of PTP1B in complex with FMOPL000587a
Descriptor: 2-(benzyloxy)benzohydrazide, 2-AMINO-2-HYDROXYMETHYL-PROPANE-1,3-DIOL, Tyrosine-protein phosphatase non-receptor type 1
Authors:Mehlman, T, Ginn, H.M, Keedy, D.A.
Deposit date:2024-01-03
Release date:2024-01-24
Last modified:2024-04-24
Method:X-RAY DIFFRACTION (1.78 Å)
Cite:An expanded view of ligandability in the allosteric enzyme PTP1B from computational reanalysis of large-scale crystallographic data.
Biorxiv, 2024
7GTS
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BU of 7gts by Molmil
PanDDA Analysis group deposition -- Crystal structure of PTP1B in complex with FMOPL000604a
Descriptor: 2-AMINO-2-HYDROXYMETHYL-PROPANE-1,3-DIOL, N-(4-methoxyphenyl)glycinamide, Tyrosine-protein phosphatase non-receptor type 1
Authors:Mehlman, T, Ginn, H.M, Keedy, D.A.
Deposit date:2024-01-03
Release date:2024-01-24
Last modified:2024-04-24
Method:X-RAY DIFFRACTION (1.8 Å)
Cite:An expanded view of ligandability in the allosteric enzyme PTP1B from computational reanalysis of large-scale crystallographic data.
Biorxiv, 2024

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數據於2024-07-24公開中

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