7SUM

Crystal structure of human ligase I with nick duplexes containing cognate A:T

Summary for 7SUM

• Entry DOI: 10.2210/pdb7sum/pdb
• Descriptor: DNA ligase 1, DNA(5'-*GP*CP*TP*GP*AP*TP*GP*CP*GP*TP*A-3'), DNA(5'-P*GP*TP*CP*GP*GP*AP*C-3'), ... (6 entities in total)
• Functional Keywords: ligase-dna complex, ligase/dna
• Biological source: Homo sapiens (Human); More
• Total number of polymer chains: 4
• Total formula weight: 84378.67

Authors

Tang, Q.,Gulkis, M.,McKenna, R.,Caglayan, M. (deposition date: 2021-11-17, release date: 2022-07-13, Last modification date: 2023-10-18)

• Primary citation: Tang, Q.,Gulkis, M.,McKenna, R.,Caglayan, M.; Structures of LIG1 that engage with mutagenic mismatches inserted by pol beta in base excision repair.; Nat Commun, 13:3860-3860, 2022; PubMed: 35790757; DOI: 10.1038/s41467-022-31585-w

Experimental method

X-RAY DIFFRACTION (2.9 Å)