PDB: 73332 resultsInfo pagesStatus searchChemie searchBIRD

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1VFG	Crystal structure of tRNA nucleotidyltransferase complexed with a primer tRNA and an incoming ATP analog Descriptor: DIPHOSPHOMETHYLPHOSPHONIC ACID ADENOSYL ESTER, RNA (75-MER), poly A polymerase Authors: Tomita, K, Fukai, S, Ishitani, R, Ueda, T, Takeuchi, N, Vassylyev, D.G, Nureki, O, RIKEN Structural Genomics/Proteomics Initiative (RSGI) Deposit date: 2004-04-13 Release date: 2004-08-10 Last modified: 2023-12-27 Method: X-RAY DIFFRACTION (2.8 Å) Cite: Structural basis for template-independent RNA polymerization. Nature, 430, 2004
301D	CAPTURING THE STRUCTURE OF A CATALYTIC RNA INTERMEDIATE: RNA HAMMERHEAD RIBOZYME, MG(II)-SOAKED Descriptor: MAGNESIUM ION, RNA HAMMERHEAD RIBOZYME Authors: Scott, W.G, Murray, J.B, Arnold, J.R.P, Stoddard, B.L, Klug, A. Deposit date: 1996-12-14 Release date: 1997-01-24 Last modified: 2024-02-21 Method: X-RAY DIFFRACTION (3 Å) Cite: Capturing the structure of a catalytic RNA intermediate: the hammerhead ribozyme. Science, 274, 1996
3KW2	Crystal structure of probable rRNA-methyltransferase from Porphyromonas gingivalis Descriptor: ADENOSINE, Probable r-RNA methyltransferase Authors: Ramagopal, U.A, Toro, R, Burley, S.K, Almo, S.C, New York SGX Research Center for Structural Genomics (NYSGXRC) Deposit date: 2009-11-30 Release date: 2010-01-19 Last modified: 2021-02-10 Method: X-RAY DIFFRACTION (2 Å) Cite: Crystal structure of probable rRNA-methyltransferase from Porphyromonas gingivalis To be Published
3GS5	An all-RNA hairpin ribozyme A38N1dA variant with a product mimic substrate strand Descriptor: 2-[2-(2-HYDROXYETHOXY)ETHOXY]ETHYL DIHYDROGEN PHOSPHATE, COBALT HEXAMMINE(III), RNA (25-MER), ... Authors: Spitale, R.C, Volpini, R, Heller, M.G, Krucinska, J, Cristalli, G, Wedekind, J.E. Deposit date: 2009-03-26 Release date: 2009-04-21 Last modified: 2024-02-21 Method: X-RAY DIFFRACTION (2.75 Å) Cite: Identification of an imino group indispensable for cleavage by a small ribozyme. J.Am.Chem.Soc., 131, 2009
1WNE	Foot and Mouth Disease Virus RNA-dependent RNA polymerase in complex with a template-primer RNA Descriptor: 5'-R(*CP*AP*UP*GP*GP*GP*CP*C)-3', 5'-R(*GP*GP*CP*CP*C)-3', MAGNESIUM ION, ... Authors: Ferrer-Orta, C, Arias, A, Perez-Luque, R, Escarmis, C, Domingo, E, Verdaguer, N. Deposit date: 2004-07-31 Release date: 2004-08-31 Last modified: 2023-10-25 Method: X-RAY DIFFRACTION (3 Å) Cite: Structure of Foot-and-Mouth Disease Virus RNA-dependent RNA Polymerase and Its Complex with a Template-Primer RNA J.Biol.Chem., 279, 2004
1UN6	THE CRYSTAL STRUCTURE OF A ZINC FINGER - RNA COMPLEX REVEALS TWO MODES OF MOLECULAR RECOGNITION Descriptor: 5S RIBOSOMAL RNA, MAGNESIUM ION, TRANSCRIPTION FACTOR IIIA, ... Authors: Lu, D, Searles, M.A, Klug, A. Deposit date: 2003-09-04 Release date: 2003-11-20 Last modified: 2024-05-08 Method: X-RAY DIFFRACTION (3.1 Å) Cite: Crystal Structure of a Zinc-Finger-RNA Complex Reveals Two Modes of Molecular Recognition Nature, 426, 2003
3LRN	Crystal structure of human RIG-I CTD bound to a 14 bp GC 5' ppp dsRNA Descriptor: Probable ATP-dependent RNA helicase DDX58, RNA (5'-R(*(GTP)P*GP*CP*GP*CP*GP*CP*GP*CP*GP*CP*GP*CP*C)-3'), ZINC ION Authors: Li, P. Deposit date: 2010-02-11 Release date: 2010-06-02 Last modified: 2024-04-03 Method: X-RAY DIFFRACTION (2.6 Å) Cite: The Structural Basis of 5' Triphosphate Double-Stranded RNA Recognition by RIG-I C-Terminal Domain. Structure, 18, 2010
5V3F	Co-crystal structure of the fluorogenic RNA Mango Descriptor: 4-{[(2S)-3-{2,16-dioxo-20-[(3aS,4S,6aR)-2-oxohexahydro-1H-thieno[3,4-d]imidazol-4-yl]-6,9,12-trioxa-3,15-diazaicosan-1-yl}-2,3-dihydro-1,3-benzothiazol-2-yl]methyl}-1-methylquinolin-1-ium, PHOSPHATE ION, POTASSIUM ION, ... Authors: Trachman, R.J, Ferre-D'Amare, A.R. Deposit date: 2017-03-07 Release date: 2017-05-24 Last modified: 2024-03-06 Method: X-RAY DIFFRACTION (1.7 Å) Cite: Structural basis for high-affinity fluorophore binding and activation by RNA Mango. Nat. Chem. Biol., 13, 2017
2MQV	Solution NMR structure of the U5-primer binding site (U5-PBS) domain of murine leukemia virus RNA genome bound to the retroviral nucleocapsid protein Descriptor: Nucleocapsid protein p10, RNA (68-MER), ZINC ION Authors: D'Souza, V.M, Yildiz, Z. Deposit date: 2014-06-27 Release date: 2014-09-17 Last modified: 2024-05-01 Method: SOLUTION NMR Cite: A structure-based mechanism for tRNA and retroviral RNA remodelling during primer annealing. Nature, 515, 2014
2EVY	GNYA tetranucleotide loops found in poliovirus oriL by in vivo SELEX (un)expectedly form a YNMG-like structure Descriptor: Poliovirus 5'NTR cloverleaf stem loop D mutant Authors: Melchers, W.J.G, Zoll, J, Tessari, M, Bakhmutov, D.V, Gmyl, A.P, Agol, V.I, Heus, H.A. Deposit date: 2005-11-01 Release date: 2006-08-22 Last modified: 2024-05-22 Method: SOLUTION NMR Cite: A GCUA tetranucleotide loop found in the poliovirus oriL by in vivo SELEX (un)expectedly forms a YNMG-like structure: Extending the YNMG family with GYYA. RNA, 12, 2006
2YKG	Structural insights into RNA recognition by RIG-I Descriptor: 5'-R(*GP*CP*GP*CP*GP*CP*GP*CP*GP*CP)-3', PROBABLE ATP-DEPENDENT RNA HELICASE DDX58, SULFATE ION, ... Authors: Luo, D, Pyle, A.M. Deposit date: 2011-05-27 Release date: 2011-10-26 Method: X-RAY DIFFRACTION (2.5 Å) Cite: Structural Insights Into RNA Recognition by Rig-I. Cell(Cambridge,Mass.), 147, 2011
4HHT	T. maritima RNase H2 G21S in complex with nucleic acid substrate and calcium ions Descriptor: CALCIUM ION, DNA (5'-D(*GP*AP*AP*TP*CP*AP*GP*GP*TP*GP*TP*C)-3'), DNA/RNA (5'-D(*GP*AP*CP*AP*C)-R(P*C)-D(P*TP*GP*AP*TP*TP*C)-3'), ... Authors: Rychlik, M.P, Nowotny, M. Deposit date: 2012-10-10 Release date: 2013-02-06 Last modified: 2024-02-28 Method: X-RAY DIFFRACTION (3.1 Å) Cite: RNase H2 roles in genome integrity revealed by unlinking its activities. Nucleic Acids Res., 41, 2013
3KS8	Crystal structure of Reston ebolavirus VP35 RNA binding domain in complex with 18bp dsRNA Descriptor: 5'-R(*AP*GP*AP*AP*GP*GP*AP*GP*GP*GP*AP*GP*GP*GP*AP*GP*GP*A)-3', 5'-R(*UP*CP*CP*UP*CP*CP*CP*UP*CP*CP*CP*UP*CP*CP*UP*UP*CP*U)-3', Polymerase cofactor VP35 Authors: Kimberlin, C.R, Bornholdt, Z.A, Li, S, Woods, V.L, Macrae, I.J, Saphire, E.O. Deposit date: 2009-11-20 Release date: 2010-01-12 Last modified: 2023-09-06 Method: X-RAY DIFFRACTION (2.401 Å) Cite: Ebolavirus VP35 uses a bimodal strategy to bind dsRNA for innate immune suppression. Proc.Natl.Acad.Sci.USA, 107, 2009
1M5O	Transition State Stabilization by a Catalytic RNA Descriptor: CALCIUM ION, RNA SUBSTRATE, RNA HAIRPIN RIBOZYME, ... Authors: Rupert, P.B, Massey, A.P, Sigurdsson, S.T, Ferre-D'Amare, A.R. Deposit date: 2002-07-09 Release date: 2002-10-12 Last modified: 2024-02-14 Method: X-RAY DIFFRACTION (2.2 Å) Cite: Transition state stabilization by a catalytic RNA Science, 298, 2002
3GS1	An all-RNA Hairpin Ribozyme with mutation A38N1dA Descriptor: 2-[2-(2-HYDROXYETHOXY)ETHOXY]ETHYL DIHYDROGEN PHOSPHATE, COBALT HEXAMMINE(III), RNA (5'-R(*CP*GP*GP*UP*GP*AP*GP*AP*AP*GP*GP*G)-3'), ... Authors: Spitale, R.C, Volpini, R, Heller, M.G, Krucinska, J, Cristalli, G, Wedekind, J.E. Deposit date: 2009-03-26 Release date: 2009-05-12 Last modified: 2024-02-21 Method: X-RAY DIFFRACTION (2.85 Å) Cite: Identification of an imino group indispensable for cleavage by a small ribozyme. J.Am.Chem.Soc., 131, 2009
3BBM	Minimally Junctioned Hairpin Ribozyme Incorporates A38C and 2'O-Me Modification at Active Site Descriptor: COBALT HEXAMMINE(III), Loop A Substrate strand, Loop A and Loop B Ribozyme strand, ... Authors: MacElrevey, C, Krucinska, J, Wedekind, J.E. Deposit date: 2007-11-09 Release date: 2008-08-12 Last modified: 2023-08-30 Method: X-RAY DIFFRACTION (2.65 Å) Cite: Structural effects of nucleobase variations at key active site residue Ade38 in the hairpin ribozyme. Rna, 14, 2008
2WYM	Structure of a metallo-b-lactamase Descriptor: CITRATE ANION, GLYCEROL, L-ASCORBATE-6-PHOSPHATE LACTONASE ULAG, ... Authors: Garces, F, Fernandez, F.J, Penya-Soler, E, Aguilar, J, Baldoma, L, Coll, M, Badia, J, Vega, M.C. Deposit date: 2009-11-16 Release date: 2010-04-14 Last modified: 2023-12-20 Method: X-RAY DIFFRACTION (2.6 Å) Cite: Molecular Architecture of the Mn(2+)Dependent Lactonase Ulag Reveals an Rnase-Like Metallo-Beta-Lactamase Fold and a Novel Quaternary Structure. J.Mol.Biol., 398, 2010
1M5V	Transition State Stabilization by a Catalytic RNA Descriptor: (4S)-2-METHYL-2,4-PENTANEDIOL, CALCIUM ION, RNA HAIRPIN RIBOZYME, ... Authors: Rupert, P.B, Massey, A.P, Sigurdsson, S.T, Ferre-D'Amare, A.R. Deposit date: 2002-07-09 Release date: 2002-10-12 Last modified: 2024-02-14 Method: X-RAY DIFFRACTION (2.4 Å) Cite: Transition state stabilization by a catalytic RNA Science, 298, 2002
3J9B	Electron cryo-microscopy of an RNA polymerase Descriptor: Polymerase, Polymerase basic protein 2, RNA (5'-R(*UP*UP*UP*UP*UP*A)-3'), ... Authors: Chang, S.H, Sun, D.P, Liang, H.H, Wang, J, Li, J, Guo, L, Wang, X.L, Guan, C.C, Boruah, B.M, Yuan, L.M, Feng, F, Yang, M.R, Wojdyla, J, Wang, J.W, Wang, M.T, Wang, H.W, Liu, Y.F. Deposit date: 2014-12-16 Release date: 2015-02-18 Last modified: 2024-03-20 Method: ELECTRON MICROSCOPY (4.3 Å) Cite: Cryo-EM Structure of Influenza Virus RNA Polymerase Complex at 4.3 angstrom Resolution. Mol.Cell, 2015
1M5P	Transition State Stabilization by a Catalytic RNA Descriptor: CALCIUM ION, RNA HAIRPIN RIBOZYME, RNA INHIBITOR SUBSTRATE, ... Authors: Rupert, P.B, Massey, A, Sigurdsson, S.T, Ferre-D'Amare, A.R. Deposit date: 2002-07-09 Release date: 2002-10-12 Last modified: 2024-02-14 Method: X-RAY DIFFRACTION (2.6 Å) Cite: Transition state stabilization by a catalytic RNA Science, 298, 2002
2WYL	Apo structure of a metallo-b-lactamase Descriptor: FORMYL GROUP, GLYCEROL, L-ASCORBATE-6-PHOSPHATE LACTONASE ULAG Authors: Garces, F, Fernandez, F.J, Penya-Soler, E, Aguilar, J, Baldoma, L, Coll, M, Badia, J, Vega, M.C. Deposit date: 2009-11-16 Release date: 2010-04-14 Last modified: 2011-07-13 Method: X-RAY DIFFRACTION (2.59 Å) Cite: Molecular Architecture of the Mn(2+)Dependent Lactonase Ulag Reveals an Rnase-Like Metallo-Beta-Lactamase Fold and a Novel Quaternary Structure. J.Mol.Biol., 398, 2010
3IHQ	Crystal Structure of Reduced C10S Spx in Complex with the Alpha C-terminal Domain of RNA Polymeras Descriptor: DNA-directed RNA polymerase subunit alpha, IMIDAZOLE, Regulatory protein spx Authors: Newberry, K.J, Brennan, R.G. Deposit date: 2009-07-30 Release date: 2010-02-02 Last modified: 2023-09-06 Method: X-RAY DIFFRACTION (1.9 Å) Cite: Promoter recognition by a complex of Spx and the C-terminal domain of the RNA polymerase alpha subunit. Plos One, 5, 2010
3KNC	Crystal structure of the CeNA-RNA hybrid octamer ce(GCGTAGCG):r(CGCUACGC) Descriptor: 5'-D(*(XGR)P*(XCR)P*(XGR)P*(XTR)P*(XAR)P*(XGR)P*(XCR)P*(XGR)P*(XGR))-3', 5'-R(*CP*GP*CP*UP*AP*CP*GP*C)-3', MAGNESIUM ION Authors: Ovaere, M, Van Meervelt, L. Deposit date: 2009-11-12 Release date: 2010-12-08 Last modified: 2024-02-21 Method: X-RAY DIFFRACTION (2.5 Å) Cite: The Crystal Structure of the CeNA:RNA Hybrid ce(GCGTAGCG):r(CGCUACGC). Chemistry, 17, 2011
3B91	Minimally Hinged Hairpin Ribozyme Incorporates Ade38(2AP) and 2',5'-Phosphodiester Linkage Mutations at the Active Site Descriptor: 29-mer Loop A and Loop B Ribozyme strand, COBALT HEXAMMINE(III), Loop A Substrate strand, ... Authors: MacElrevey, C, Krucinska, J, Wedekind, J.E. Deposit date: 2007-11-02 Release date: 2008-08-12 Last modified: 2023-08-30 Method: X-RAY DIFFRACTION (2.75 Å) Cite: Structural effects of nucleobase variations at key active site residue Ade38 in the hairpin ribozyme. Rna, 14, 2008
3CDW	Crystal structure of coxsackievirus B3 RNA-dependent RNA polymerase (3Dpol) in complex with protein primer VPg and a pyrophosphate Descriptor: ACETATE ION, CHLORIDE ION, GLYCEROL, ... Authors: Gruez, A, Selisko, B, Roberts, M, Bricogne, G, Bussetta, C, Canard, B. Deposit date: 2008-02-27 Release date: 2008-07-22 Last modified: 2023-11-01 Method: X-RAY DIFFRACTION (2.5 Å) Cite: The crystal structure of coxsackievirus B3 RNA-dependent RNA polymerase in complex with its protein primer VPg confirms the existence of a second VPg binding site on Picornaviridae polymerases J.Virol., 82, 2008

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