4U27
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![BU of 4u27 by Molmil](/molmil-images/mine/4u27) | Crystal structure of the E. coli ribosome bound to flopristin and linopristin. | Descriptor: | 16S rRNA, 23S rRNA, 30S ribosomal protein S10, ... | Authors: | Noeske, J, Huang, J, Olivier, N.B, Giacobbe, R.A, Zambrowski, M, Cate, J.H.D. | Deposit date: | 2014-07-16 | Release date: | 2014-07-30 | Last modified: | 2024-07-10 | Method: | X-RAY DIFFRACTION (2.8 Å) | Cite: | Synergy of streptogramin antibiotics occurs independently of their effects on translation. Antimicrob.Agents Chemother., 58, 2014
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4B6M
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2JEW
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1M71
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![BU of 1m71 by Molmil](/molmil-images/mine/1m71) | Crystal structure of a Monoclonal Fab Specific for Shigella Flexneri Y lipopolysaccharide | Descriptor: | heavy chain of the monoclonal antibody Fab SYA/J6, light chain of the monoclonal antibody Fab SYA/J6 | Authors: | Vyas, N.K, Vyas, M.N, Chervenak, M.C, Johnson, M.A, Pinto, B.M, Bundle, D.R, Quiocho, F.A. | Deposit date: | 2002-07-18 | Release date: | 2003-07-22 | Last modified: | 2011-07-13 | Method: | X-RAY DIFFRACTION (2.8 Å) | Cite: | Molecular Recognition of Oligosaccharide Epitopes by a Monoclonal Fab Specific for
Shigella flexneri Y Lipopolysaccharide: X-ray Structures and Thermodyanamics Biochemistry, 41, 2002
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1CNF
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![BU of 1cnf by Molmil](/molmil-images/mine/1cnf) | STRUCTURAL STUDIES ON CORN NITRATE REDUCTASE: REFINED STRUCTURE OF THE CYTOCHROME B REDUCTASE FRAGMENT AT 2.5 ANGSTROMS, ITS ADP COMPLEX AND AN ACTIVE SITE MUTANT AND MODELING OF THE CYTOCHROME B DOMAIN | Descriptor: | ADENOSINE-5'-DIPHOSPHATE, FLAVIN-ADENINE DINUCLEOTIDE, NITRATE REDUCTASE | Authors: | Lu, G, Lindqvist, Y, Schneider, G. | Deposit date: | 1995-02-01 | Release date: | 1995-04-20 | Last modified: | 2024-02-07 | Method: | X-RAY DIFFRACTION (2.7 Å) | Cite: | Structural studies on corn nitrate reductase: refined structure of the cytochrome b reductase fragment at 2.5 A, its ADP complex and an active-site mutant and modeling of the cytochrome b domain. J.Mol.Biol., 248, 1995
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1CFL
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![BU of 1cfl by Molmil](/molmil-images/mine/1cfl) | DNA DECAMER DUPLEX CONTAINING T5-T6 PHOTOADDUCT | Descriptor: | DNA (5'-D(*CP*GP*CP*AP*(64T)P*TP*AP*CP*GP*C)-3'), DNA (5'-D(*GP*CP*GP*TP*GP*AP*TP*GP*CP*G)-3') | Authors: | Lee, J.-H, Hwang, G.-S, Choi, B.-S. | Deposit date: | 1999-03-19 | Release date: | 1999-05-28 | Last modified: | 2023-12-27 | Method: | SOLUTION NMR | Cite: | Solution structure of a DNA decamer duplex containing the stable 3' T.G base pair of the pyrimidine(6-4)pyrimidone photoproduct [(6-4) adduct]: implications for the highly specific 3' T --> C transition of the (6-4) adduct. Proc.Natl.Acad.Sci.USA, 96, 1999
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2QKF
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![BU of 2qkf by Molmil](/molmil-images/mine/2qkf) | Crystal structure of 3-deoxy-d-manno-octulosonate 8-phosphate synthase (KDO8PS) from Neisseria meningitidis | Descriptor: | 3-deoxy-D-manno-octulosonic acid 8- phosphate synthetase, CHLORIDE ION, GLYCEROL, ... | Authors: | Cochrane, F.C, Patchett, M.L, Jameson, G.B, Parker, E.J. | Deposit date: | 2007-07-11 | Release date: | 2008-07-01 | Last modified: | 2023-08-30 | Method: | X-RAY DIFFRACTION (1.75 Å) | Cite: | Re-Establishing a Metal-Binding Scaffold with Full Activity in the Metal-Independent Kdo8P Synthase from Neisseria Meningitidis To be Published
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3HC8
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![BU of 3hc8 by Molmil](/molmil-images/mine/3hc8) | Investigation of Aminopyridiopyrazinones as PDE5 Inhibitors: Evaluation of Modifications to the Central Ring System. | Descriptor: | 6-(6-methoxypyridin-3-yl)-2-[(2-morpholin-4-ylethyl)amino]-4-(2-propoxyethyl)pyrido[2,3-b]pyrazin-3(4H)-one, MAGNESIUM ION, ZINC ION, ... | Authors: | Hughes, R.O, Stallings, W.C, Cubbage, J.W, Williams, J.M. | Deposit date: | 2009-05-05 | Release date: | 2009-07-07 | Last modified: | 2024-05-22 | Method: | X-RAY DIFFRACTION (1.79 Å) | Cite: | Investigation of aminopyridiopyrazinones as PDE5 inhibitors: Evaluation of modifications to the central ring system. Bioorg.Med.Chem.Lett., 19, 2009
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2FMN
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![BU of 2fmn by Molmil](/molmil-images/mine/2fmn) | Ala177Val mutant of E. coli Methylenetetrahydrofolate Reductase complex with LY309887 | Descriptor: | 5,10-methylenetetrahydrofolate reductase, FLAVIN-ADENINE DINUCLEOTIDE, N-[(5-{2-[(6R)-2-AMINO-4-OXO-3,4,5,6,7,8-HEXAHYDROPYRIDO[2,3-D]PYRIMIDIN-6-YL]ETHYL}-2-THIENYL)CARBONYL]-L-GLUTAMIC ACID | Authors: | Pejchal, R, Campbell, E, Guenther, B.D, Lennon, B.W, Matthews, R.G, Ludwig, M.L. | Deposit date: | 2006-01-09 | Release date: | 2006-04-25 | Last modified: | 2023-08-30 | Method: | X-RAY DIFFRACTION (2.05 Å) | Cite: | Structural Perturbations in the Ala -> Val Polymorphism of Methylenetetrahydrofolate Reductase: How Binding of Folates May Protect against Inactivation Biochemistry, 45, 2006
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2FMO
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![BU of 2fmo by Molmil](/molmil-images/mine/2fmo) | Ala177Val mutant of E. coli Methylenetetrahydrofolate Reductase | Descriptor: | (4S)-2-METHYL-2,4-PENTANEDIOL, 5,10-methylenetetrahydrofolate reductase, FLAVIN-ADENINE DINUCLEOTIDE, ... | Authors: | Pejchal, R, Campbell, E, Guenther, B.D, Lennon, B.W, Matthews, R.G, Ludwig, M.L. | Deposit date: | 2006-01-09 | Release date: | 2006-04-25 | Last modified: | 2023-08-30 | Method: | X-RAY DIFFRACTION (2.25 Å) | Cite: | Structural Perturbations in the Ala -> Val Polymorphism of Methylenetetrahydrofolate Reductase: How Binding of Folates May Protect against Inactivation Biochemistry, 45, 2006
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4K4Y
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![BU of 4k4y by Molmil](/molmil-images/mine/4k4y) | Coxsackievirus B3 polymerase elongation complex (r2+1_form) | Descriptor: | 2',3'-DIDEOXYCYTIDINE 5'-TRIPHOSPHATE, ACETATE ION, DNA/RNA (5'-R(*UP*GP*UP*UP*CP*GP*AP*CP*GP*AP*GP*AP*GP*AP*(DOC))-3'), ... | Authors: | Gong, P, Peersen, O.B. | Deposit date: | 2013-04-12 | Release date: | 2013-05-29 | Last modified: | 2024-02-28 | Method: | X-RAY DIFFRACTION (2.72 Å) | Cite: | Structures of coxsackievirus, rhinovirus, and poliovirus polymerase elongation complexes solved by engineering RNA mediated crystal contacts. Plos One, 8, 2013
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2AKQ
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![BU of 2akq by Molmil](/molmil-images/mine/2akq) | The structure of bovine B-lactoglobulin A in crystals grown at very low ionic strength | Descriptor: | Beta-lactoglobulin variant A | Authors: | Adams, J.J, Anderson, B.F, Norris, G.E, Creamer, L.K, Jameson, G.B. | Deposit date: | 2005-08-03 | Release date: | 2005-08-16 | Last modified: | 2023-10-25 | Method: | X-RAY DIFFRACTION (3 Å) | Cite: | Structure of bovine beta-lactoglobulin (variant A) at very low ionic strength J.Struct.Biol., 154, 2006
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2LAR
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![BU of 2lar by Molmil](/molmil-images/mine/2lar) | DNA / RNA Hybrid containing a central stereo specific Rp borano phosphate linkage | Descriptor: | DNA_(5'-D(*AP*TP*GP*GP*TP*BGR*CP*TP*C)-3')_, RNA_(5'-R(*GP*AP*GP*CP*AP*CP*CP*AP*U)-3')_ | Authors: | Johnson, C.N, Spring, A.M, Shaw, B.R, Germann, M.W. | Deposit date: | 2011-03-18 | Release date: | 2011-10-12 | Last modified: | 2024-05-01 | Method: | SOLUTION NMR | Cite: | Structural basis of the RNase H1 activity on stereo regular borano phosphonate DNA/RNA hybrids. Biochemistry, 50, 2011
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2LB4
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![BU of 2lb4 by Molmil](/molmil-images/mine/2lb4) | DNA / RNA Hybrid containing a central stereo specific Sp borano phosphate linkage | Descriptor: | DNA_(5'-D(*AP*TP*GP*GP*TP*BGR*CP*TP*C)-3')_, RNA_(5'-R(*GP*AP*GP*CP*AP*CP*CP*AP*U)-3')_ | Authors: | Johnson, C.N, Spring, A.M, Shaw, B.R, Germann, M.W. | Deposit date: | 2011-03-22 | Release date: | 2011-06-29 | Last modified: | 2024-05-01 | Method: | SOLUTION NMR | Cite: | Structural Basis of the RNase H1 Activity on Stereo Regular Borano Phosphonate DNA/RNA Hybrids. Biochemistry, 50, 2011
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4C0M
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![BU of 4c0m by Molmil](/molmil-images/mine/4c0m) | Crystal Structure of the N terminal domain of wild type TRIF (TIR- domain-containing adapter-inducing interferon-beta) | Descriptor: | TIR DOMAIN-CONTAINING ADAPTER MOLECULE 1 | Authors: | Ullah, M.O, Ve, T, Mangan, M, Alaidarous, M, Sweet, M.J, Mansell, A, Kobe, B. | Deposit date: | 2013-08-05 | Release date: | 2013-12-11 | Last modified: | 2023-12-20 | Method: | X-RAY DIFFRACTION (2.8 Å) | Cite: | The Tlr Signalling Adaptor Trif/Ticam-1 Has an N-Terminal Helical Domain with Structural Similarity to Ifit Proteins Acta Crystallogr.,Sect.D, 69, 2013
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1SNJ
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![BU of 1snj by Molmil](/molmil-images/mine/1snj) | Solution structure of the DNA three-way junction with the A/C-stacked conformation | Descriptor: | 36-MER | Authors: | Wu, B, Girard, F, van Buuren, B, Schleucher, J, Tessari, M, Wijmenga, S. | Deposit date: | 2004-03-11 | Release date: | 2005-04-05 | Last modified: | 2024-05-22 | Method: | SOLUTION NMR | Cite: | Global structure of a DNA three-way junction by solution NMR: towards prediction of 3H fold. Nucleic Acids Res., 32, 2004
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1MOE
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![BU of 1moe by Molmil](/molmil-images/mine/1moe) | The three-dimensional structure of an engineered scFv T84.66 dimer or diabody in VL to VH linkage. | Descriptor: | SULFATE ION, anti-CEA mAb T84.66 | Authors: | Carmichael, J.A, Power, B.E, Garrett, T.P.J, Yazaki, P.J, Shively, J.E, Raubischek, A.A, Wu, A.M, Hudson, P.J. | Deposit date: | 2002-09-09 | Release date: | 2003-03-18 | Last modified: | 2023-10-25 | Method: | X-RAY DIFFRACTION (2.6 Å) | Cite: | The Crystal Structure of an Anti-CEA scFv Diabody Assembled from T84.66 scFvs in VL-to-VH Orientation: Implications for Diabody Flexibility J.Mol.Biol., 326, 2003
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3IK3
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2CXG
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![BU of 2cxg by Molmil](/molmil-images/mine/2cxg) | CYCLODEXTRIN GLYCOSYLTRANSFERASE COMPLEXED TO THE INHIBITOR ACARBOSE | Descriptor: | 6-AMINO-4-HYDROXYMETHYL-CYCLOHEX-4-ENE-1,2,3-TRIOL, CALCIUM ION, CYCLODEXTRIN GLYCOSYLTRANSFERASE, ... | Authors: | Strokopytov, B.V, Uitdehaag, J.C.M, Ruiterkamp, R, Dijkstra, B.W. | Deposit date: | 1998-05-08 | Release date: | 1998-10-14 | Last modified: | 2023-08-09 | Method: | X-RAY DIFFRACTION (2.5 Å) | Cite: | X-ray structure of cyclodextrin glycosyltransferase complexed with acarbose. Implications for the catalytic mechanism of glycosidases. Biochemistry, 34, 1995
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2IXA
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![BU of 2ixa by Molmil](/molmil-images/mine/2ixa) | A-zyme, N-acetylgalactosaminidase | Descriptor: | (4R)-2-METHYLPENTANE-2,4-DIOL, (4S)-2-METHYL-2,4-PENTANEDIOL, ALPHA-N-ACETYLGALACTOSAMINIDASE, ... | Authors: | Sulzenbacher, G, Liu, Q.P, Bourne, Y, Henrissat, B, Clausen, H. | Deposit date: | 2006-07-07 | Release date: | 2007-04-10 | Last modified: | 2024-05-08 | Method: | X-RAY DIFFRACTION (2.3 Å) | Cite: | Bacterial Glycosidases for the Production of Universal Red Blood Cells. Nat.Biotechnol., 25, 2007
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1IXQ
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![BU of 1ixq by Molmil](/molmil-images/mine/1ixq) | Enzyme-Phosphate2 Complex of Pyridoxine 5'-Phosphate synthase | Descriptor: | PHOSPHATE ION, Pyridoxine 5'-phosphate Synthase | Authors: | Garrido-Franco, M, Laber, B, Huber, R, Clausen, T. | Deposit date: | 2002-06-28 | Release date: | 2003-02-11 | Last modified: | 2024-04-03 | Method: | X-RAY DIFFRACTION (2.3 Å) | Cite: | Enzyme-ligand complexes of pyridoxine 5'-phosphate synthase: implications for substrate binding and catalysis J.MOL.BIOL., 321, 2002
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1N1K
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![BU of 1n1k by Molmil](/molmil-images/mine/1n1k) | NMR Structure for d(CCGCGG)2 | Descriptor: | 5'-D(P*CP*CP*GP*CP*GP*G)-3' | Authors: | Monleon, D, Celda, B. | Deposit date: | 2002-10-18 | Release date: | 2002-10-30 | Last modified: | 2024-05-22 | Method: | SOLUTION NMR | Cite: | NMR study of hexanucleotide d(CCGCGG)(2) containing two triplet repeats of
fragile X syndrome. Biochem.Biophys.Res.Commun., 303, 2003
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4D6C
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![BU of 4d6c by Molmil](/molmil-images/mine/4d6c) | Crystal structure of a family 98 glycoside hydrolase catalytic module (Sp3GH98)(L19 mutant) | Descriptor: | 1,2-ETHANEDIOL, GLYCOSIDE HYDROLASE | Authors: | Kwan, D.H, Constantinescu, I, Chapanian, R, Higgins, M.A, Samain, E, Boraston, A.B, Kizhakkedathu, J.N, Withers, S.G. | Deposit date: | 2014-11-11 | Release date: | 2014-11-26 | Last modified: | 2023-12-20 | Method: | X-RAY DIFFRACTION (1.59 Å) | Cite: | Towards Efficient Enzymes for the Generation of Universal Blood Through Structure-Guided Directed Evolution. J.Am.Chem.Soc., 137, 2015
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1SGS
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![BU of 1sgs by Molmil](/molmil-images/mine/1sgs) | Crystal structure of a free kB DNA | Descriptor: | CALCIUM ION, kB DNA | Authors: | Huang, D.B, Phelps, C.B, Fusco, A.J, Ghosh, G. | Deposit date: | 2004-02-24 | Release date: | 2004-03-23 | Last modified: | 2023-08-23 | Method: | X-RAY DIFFRACTION (1.6 Å) | Cite: | Crystal structure of a free kappaB DNA: insights into DNA recognition by transcription factor NF-kappaB. J.Mol.Biol., 346, 2005
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1IPJ
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![BU of 1ipj by Molmil](/molmil-images/mine/1ipj) | CRYSTAL STRUCTURES OF RECOMBINANT AND NATIVE SOYBEAN BETA-CONGLYCININ BETA HOMOTRIMERS COMPLEXES WITH N-ACETYL-D-GLUCOSAMINE | Descriptor: | 2-acetamido-2-deoxy-beta-D-glucopyranose, BETA-CONGLYCININ, BETA CHAIN | Authors: | Maruyama, N, Adachi, M, Takahashi, K, Yagasaki, K, Kohno, M, Takenaka, Y, Okuda, E, Nakagawa, S, Mikami, B, Utsumi, S. | Deposit date: | 2001-05-16 | Release date: | 2002-05-16 | Last modified: | 2023-12-27 | Method: | X-RAY DIFFRACTION (2.7 Å) | Cite: | Crystal structures of recombinant and native soybean beta-conglycinin beta homotrimers. Eur.J.Biochem., 268, 2001
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