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3BIK
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BU of 3bik by Molmil
Crystal Structure of the PD-1/PD-L1 Complex
Descriptor: GLYCEROL, Programmed cell death 1 ligand 1, Programmed cell death protein 1
Authors:Lin, D.Y, Tanaka, Y, Iwasaki, M, Gittis, A.G, Su, H.P, Mikami, B, Okazaki, T, Honjo, T, Minato, N, Garboczi, D.N.
Deposit date:2007-11-30
Release date:2008-02-26
Last modified:2023-08-30
Method:X-RAY DIFFRACTION (2.65 Å)
Cite:The PD-1/PD-L1 complex resembles the antigen-binding Fv domains of antibodies and T cell receptors.
Proc.Natl.Acad.Sci.Usa, 105, 2008
6QNA
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BU of 6qna by Molmil
Structure of bovine anti-RSV hybrid Fab B13HC-B4LC
Descriptor: B13 Heavy chain, B4 light chain, GLYCEROL
Authors:Ren, J, Nettleship, J.E, Harris, G, Mwangi, W, Rhaman, N, Grant, C, Kotecha, A, Fry, E, Charleston, B, Stuart, D.I, Hammond, J, Owens, R.J.
Deposit date:2019-02-10
Release date:2019-05-29
Last modified:2024-01-24
Method:X-RAY DIFFRACTION (2.62 Å)
Cite:The role of the light chain in the structure and binding activity of two cattle antibodies that neutralize bovine respiratory syncytial virus.
Mol.Immunol., 112, 2019
6QN9
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BU of 6qn9 by Molmil
Structure of bovine anti-RSV Fab B4
Descriptor: GLYCEROL, Heavy chain, SULFATE ION, ...
Authors:Ren, J, Nettleship, J.E, Harris, G, Mwangi, W, Rhaman, N, Grant, C, Kotecha, A, Fry, E, Charleston, B, Stuart, D.I, Hammond, J, Owens, R.J.
Deposit date:2019-02-10
Release date:2019-05-29
Last modified:2024-01-24
Method:X-RAY DIFFRACTION (1.89 Å)
Cite:The role of the light chain in the structure and binding activity of two cattle antibodies that neutralize bovine respiratory syncytial virus.
Mol.Immunol., 112, 2019
6QN8
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BU of 6qn8 by Molmil
Structure of bovine anti-RSV Fab B13
Descriptor: CHLORIDE ION, Heavy chain of bovine anti-RSV B13 Fab, Light chain of bovine anti-RSV Fab B13
Authors:Ren, J, Nettleship, J.E, Harris, G, Mwangi, W, Rhaman, N, Grant, C, Kotecha, A, Fry, E, Charleston, B, Stuart, D.I, Hammond, J, Owens, R.J.
Deposit date:2019-02-10
Release date:2019-05-29
Last modified:2019-08-21
Method:X-RAY DIFFRACTION (2.12 Å)
Cite:The role of the light chain in the structure and binding activity of two cattle antibodies that neutralize bovine respiratory syncytial virus.
Mol.Immunol., 112, 2019
1VES
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BU of 1ves by Molmil
Structure of New Antigen Receptor variable domain from sharks
Descriptor: New Antigen Receptor variable domain
Authors:Streltsov, V.A.
Deposit date:2004-04-05
Release date:2004-08-24
Last modified:2023-10-25
Method:X-RAY DIFFRACTION (2.18 Å)
Cite:Structural evidence for evolution of shark Ig new antigen receptor variable domain antibodies from a cell-surface receptor
Proc.Natl.Acad.Sci.USA, 101, 2004
6QN7
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BU of 6qn7 by Molmil
Structure of bovine anti-RSV hybrid Fab B4HC-B13LC
Descriptor: Heavy chain of bovine anti-RSV B4, Light chain of bovine anti-RSV B13
Authors:Ren, J, Nettleship, J.E, Harris, G, Mwangi, W, Rhaman, N, Grant, C, Kotecha, A, Fry, E, Charleston, B, Stuart, D.I, Hammond, J, Owens, R.J.
Deposit date:2019-02-10
Release date:2019-05-29
Last modified:2019-08-21
Method:X-RAY DIFFRACTION (2.15 Å)
Cite:The role of the light chain in the structure and binding activity of two cattle antibodies that neutralize bovine respiratory syncytial virus.
Mol.Immunol., 112, 2019
1VER
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BU of 1ver by Molmil
Structure of New Antigen Receptor variable domain from sharks
Descriptor: New Antigen Receptor variable domain
Authors:Streltsov, V.A.
Deposit date:2004-04-05
Release date:2004-08-24
Last modified:2023-12-27
Method:X-RAY DIFFRACTION (2.82 Å)
Cite:Structural evidence for evolution of shark Ig new antigen receptor variable domain antibodies from a cell-surface receptor
Proc.Natl.Acad.Sci.USA, 101, 2004
4MUC
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BU of 4muc by Molmil
The 4th and 5th C-terminal domains of Factor H related protein 1
Descriptor: Complement factor H-related protein 1, SULFATE ION
Authors:Bhattacharjee, A, Goldman, A, Kolodziejczyk, R, Jokiranta, T.S.
Deposit date:2013-09-21
Release date:2015-02-18
Last modified:2015-05-06
Method:X-RAY DIFFRACTION (2.897 Å)
Cite:The Major Autoantibody Epitope on Factor H in Atypical Hemolytic Uremic Syndrome Is Structurally Different from Its Homologous Site in Factor H-related Protein 1, Supporting a Novel Model for Induction of Autoimmunity in This Disease.
J.Biol.Chem., 290, 2015
8JKD
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BU of 8jkd by Molmil
Cryo-EM structure of CCHFV envelope protein Gc trimer in complex with Gc13 Fab
Descriptor: Glycoprotein C
Authors:Chong, T, Cao, S.
Deposit date:2023-06-01
Release date:2024-01-24
Last modified:2024-02-28
Method:ELECTRON MICROSCOPY (2.6 Å)
Cite:Neutralizing monoclonal antibodies against the Gc fusion loop region of Crimean-Congo hemorrhagic fever virus.
Plos Pathog., 20, 2024
2KPY
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BU of 2kpy by Molmil
Solution Structure of the major allergen of Artemisia vulgaris (Art v 1)
Descriptor: Major pollen allergen Art v 1
Authors:Razzera, G, Gadermaier, G, Almeida, M, Egger, M, Jahn-Schmid, B, Almeida, F, Ferreira, F, Valente, A.
Deposit date:2009-10-23
Release date:2010-10-06
Last modified:2023-06-14
Method:SOLUTION NMR
Cite:Mapping the interactions between a major pollen allergen and human IgE antibodies.
Structure, 18, 2010
5M15
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BU of 5m15 by Molmil
Synthetic nanobody in complex with MBP
Descriptor: Maltose-binding periplasmic protein, Synthetic nanobody L2_D09, (a-MBP#3)
Authors:Zimmermann, I, Egloff, P, Seeger, M.A.
Deposit date:2016-10-07
Release date:2017-11-15
Last modified:2019-10-16
Method:X-RAY DIFFRACTION (1.9 Å)
Cite:Synthetic single domain antibodies for the conformational trapping of membrane proteins.
Elife, 7, 2018
5M13
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BU of 5m13 by Molmil
Synthetic nanobody in complex with MBP
Descriptor: 1,2-ETHANEDIOL, Maltose-binding periplasmic protein, synthetic Nanobody L2_C06 (a-MBP#2)
Authors:Zimmermann, I, Egloff, P, Seeger, M.A.
Deposit date:2016-10-07
Release date:2017-11-15
Last modified:2019-10-16
Method:X-RAY DIFFRACTION (1.372 Å)
Cite:Synthetic single domain antibodies for the conformational trapping of membrane proteins.
Elife, 7, 2018
5M14
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BU of 5m14 by Molmil
Synthetic nanobody in complex with MBP
Descriptor: Maltose-binding periplasmic protein, synthetic Nanobody L2_G11 (a-MBP#2)
Authors:Zimmermann, I, Egloff, P, Seeger, M.A.
Deposit date:2016-10-07
Release date:2017-11-15
Last modified:2019-10-16
Method:X-RAY DIFFRACTION (1.6 Å)
Cite:Synthetic single domain antibodies for the conformational trapping of membrane proteins.
Elife, 7, 2018
3P30
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BU of 3p30 by Molmil
crystal structure of the cluster II Fab 1281 in complex with HIV-1 gp41 ectodomain
Descriptor: 1281 Fab heavy chain, 1281 Fab light chain, HIV-1 gp41
Authors:Frey, G, Chen, J, Rits-Volloch, S, Freeman, M.M, Zolla-Pazner, S, Chen, B.
Deposit date:2010-10-04
Release date:2010-11-17
Last modified:2017-11-08
Method:X-RAY DIFFRACTION (3.3 Å)
Cite:Distinct conformational states of HIV-1 gp41 are recognized by neutralizing and non-neutralizing antibodies.
Nat.Struct.Mol.Biol., 17, 2010
1WRF
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BU of 1wrf by Molmil
Refined solution structure of Der f 2, The Major Mite Allergen from Dermatophagoides farinae
Descriptor: Mite group 2 allergen Der f 2
Authors:Ichikawa, S, Takai, T, Inoue, T, Yuuki, T, Okumura, Y, Ogura, K, Inagaki, F, Hatanaka, H.
Deposit date:2004-10-15
Release date:2005-04-19
Last modified:2022-03-02
Method:SOLUTION NMR
Cite:NMR Study on the Major Mite Allergen Der f 2: Its Refined Tertiary Structure, Epitopes for Monoclonal Antibodies and Characteristics Shared by ML Protein Group Members
J.Biochem.(Tokyo), 137, 2005
5VAA
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BU of 5vaa by Molmil
Crystal structure of mouse IgG2a Fc T370K mutant
Descriptor: 2-(N-MORPHOLINO)-ETHANESULFONIC ACID, GLYCEROL, Ig gamma-2A chain C region, ...
Authors:Armstrong, A.A, Gilliland, G.L.
Deposit date:2017-03-24
Release date:2017-06-07
Last modified:2020-07-29
Method:X-RAY DIFFRACTION (1.55 Å)
Cite:Efficient Generation of Bispecific Murine Antibodies for Pre-Clinical Investigations in Syngeneic Rodent Models.
Sci Rep, 7, 2017
5YWO
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BU of 5ywo by Molmil
Structure of JEV-2F2 Fab complex
Descriptor: 2F2 heavy chain, 2F2 light chain, JEV E protein, ...
Authors:Qiu, X, Lei, Y.F, Yang, P, Gao, Q, Wang, N, Cao, L, Yuan, S, Wang, X, Xu, Z.K, Rao, Z.
Deposit date:2017-11-29
Release date:2018-03-21
Last modified:2018-09-12
Method:ELECTRON MICROSCOPY (4.7 Å)
Cite:Structural basis for neutralization of Japanese encephalitis virus by two potent therapeutic antibodies
Nat Microbiol, 3, 2018
3B9K
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BU of 3b9k by Molmil
Crystal structure of CD8alpha-beta in complex with YTS 156.7 FAB
Descriptor: 2-acetamido-2-deoxy-beta-D-glucopyranose, Fab Heavy chain, Fab Light Chain, ...
Authors:Shore, D, Wilson, I.A.
Deposit date:2007-11-05
Release date:2008-11-11
Last modified:2020-07-29
Method:X-RAY DIFFRACTION (2.7 Å)
Cite:The Crystal Structure of CD8 in Complex with YTS156.7.7 Fab and Interaction with Other CD8 Antibodies Define the Binding Mode of CD8 alphabeta to MHC Class I
J.Mol.Biol., 384, 2008
5YWF
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BU of 5ywf by Molmil
Crystal structure of 2H4 Fab
Descriptor: 2H4 heavy chain, 2H4 light chain
Authors:Qiu, X, Lei, Y, Yang, P, Gao, Q, Wang, N, Cao, L, Wang, X, Xu, Z.K, Rao, Z.
Deposit date:2017-11-29
Release date:2018-03-21
Method:X-RAY DIFFRACTION (2.206 Å)
Cite:Structural basis for neutralization of Japanese encephalitis virus by two potent therapeutic antibodies
Nat Microbiol, 3, 2018
3ZV2
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BU of 3zv2 by Molmil
Human protein-tyrosine phosphatase 1b C215A, S216A mutant
Descriptor: Tyrosine-protein phosphatase non-receptor type 1
Authors:Barford, D, Salmeen, A, Tonks, N.K.
Deposit date:2011-07-22
Release date:2011-08-31
Last modified:2023-12-20
Method:X-RAY DIFFRACTION (2.8 Å)
Cite:Conformation-sensing antibodies stabilize the oxidized form of PTP1B and inhibit its phosphatase activity.
Cell, 147, 2011
5YS2
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BU of 5ys2 by Molmil
Structure of the domain IV(D_IV) of Pseudorabies virus glycoprotein B( PRV gB)
Descriptor: Envelope glycoprotein B,Envelope glycoprotein B
Authors:Hu, X.L, Yang, F.L.
Deposit date:2017-11-12
Release date:2017-12-27
Last modified:2018-01-17
Method:X-RAY DIFFRACTION (2.698 Å)
Cite:Two classes of protective antibodies against Pseudorabies virus variant glycoprotein B: Implications for vaccine design.
PLoS Pathog., 13, 2017
5UBX
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BU of 5ubx by Molmil
Crystal structure of a mutant mIgG2b Fc heterodimer in complex with Protein A peptide analog Z34C
Descriptor: 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-2)-alpha-D-mannopyranose-(1-3)-[2-acetamido-2-deoxy-beta-D-glucopyranose-(1-2)-alpha-D-mannopyranose-(1-6)]beta-D-mannopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-2)-alpha-D-mannopyranose-(1-3)-[2-acetamido-2-deoxy-beta-D-glucopyranose-(1-2)-alpha-D-mannopyranose-(1-6)]beta-D-mannopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-[alpha-L-fucopyranose-(1-6)]2-acetamido-2-deoxy-beta-D-glucopyranose, Ig gamma-2B chain C region, ...
Authors:Armstrong, A.A, Zwolak, A, Gilliland, G.L.
Deposit date:2016-12-21
Release date:2017-09-20
Last modified:2023-10-04
Method:X-RAY DIFFRACTION (2.7 Å)
Cite:Modulation of protein A binding allows single-step purification of mouse bispecific antibodies that retain FcRn binding.
MAbs, 9, 2017
5DVN
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BU of 5dvn by Molmil
Fc K392D/K409D homodimer
Descriptor: Fc-III peptide, Ig gamma-1 chain C region
Authors:Atwell, S, Leaver-Fay, A, Froning, K.J, Aldaz, H, Pustilnik, A, Lu, F, Huang, F, Yuan, R, Dhanani, S.H, Chamberlain, A.K, Fitchett, J.R, Gutierrez, B, Hendle, J, Demarest, S.J, Kuhlman, B.
Deposit date:2015-09-21
Release date:2016-03-30
Last modified:2016-07-06
Method:X-RAY DIFFRACTION (2.5 Å)
Cite:Computationally Designed Bispecific Antibodies using Negative State Repertoires.
Structure, 24, 2016
5DVO
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BU of 5dvo by Molmil
Fc K392D/K409D homodimer
Descriptor: Ig gamma-1 chain C region, SULFATE ION
Authors:Atwell, S, Leaver-Fay, A, Froning, K.J, Aldaz, H, Pustilnik, A, Lu, F, Huang, F, Yuan, R, Dhanani, S.H, Chamberlain, A.K, Fitchett, J.R, Gutierrez, B, Hendle, J, Demarest, S.J, Kuhlman, B.
Deposit date:2015-09-21
Release date:2016-03-30
Last modified:2016-04-27
Method:X-RAY DIFFRACTION (2.5 Å)
Cite:Computationally Designed Bispecific Antibodies using Negative State Repertoires.
Structure, 24, 2016
6EUN
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BU of 6eun by Molmil
Crystal structure of Neisseria meningitidis vaccine antigen NadA variant 3
Descriptor: (4S)-2-METHYL-2,4-PENTANEDIOL, 1,2-ETHANEDIOL, 1-ETHOXY-2-(2-ETHOXYETHOXY)ETHANE, ...
Authors:Dello Iacono, L, Liguori, A, Malito, E, Bottomley, M.J.
Deposit date:2017-10-30
Release date:2018-10-10
Last modified:2024-05-08
Method:X-RAY DIFFRACTION (2.45 Å)
Cite:NadA3 Structures Reveal Undecad Coiled Coils and LOX1 Binding Regions Competed by Meningococcus B Vaccine-Elicited Human Antibodies.
MBio, 9, 2018

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數據於2024-07-24公開中

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