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1AM1
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ATP BINDING SITE IN THE HSP90 MOLECULAR CHAPERONE
Descriptor: ADENOSINE-5'-DIPHOSPHATE, HEAT SHOCK PROTEIN 90
Authors:Pearl, L.H, Roe, S.M, Prodromou, C.
Deposit date:1997-06-20
Release date:1998-06-24
Last modified:2024-05-22
Method:X-RAY DIFFRACTION (2 Å)
Cite:Identification and structural characterization of the ATP/ADP-binding site in the Hsp90 molecular chaperone
Cell(Cambridge,Mass.), 90, 1997
2ZVK
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Crystal structure of PCNA in complex with DNA polymerase eta fragment
Descriptor: DNA polymerase eta, Proliferating cell nuclear antigen
Authors:Hishiki, A, Hashimoto, H, Hanafusa, T, Kamei, K, Ohashi, E, Shimizu, T, Ohmori, H, Sato, M.
Deposit date:2008-11-11
Release date:2009-02-10
Last modified:2023-11-01
Method:X-RAY DIFFRACTION (2.7 Å)
Cite:Structural Basis for Novel Interactions between Human Translesion Synthesis Polymerases and Proliferating Cell Nuclear Antigen
J.Biol.Chem., 284, 2009
2ZVM
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BU of 2zvm by Molmil
Crystal structure of PCNA in complex with DNA polymerase iota fragment
Descriptor: DNA polymerase iota, Proliferating cell nuclear antigen
Authors:Hishiki, A, Hashimoto, H, Hanafusa, T, Kamei, K, Ohashi, E, Shimizu, T, Ohmori, H, Sato, M.
Deposit date:2008-11-11
Release date:2009-02-10
Last modified:2023-11-01
Method:X-RAY DIFFRACTION (2.3 Å)
Cite:Structural Basis for Novel Interactions between Human Translesion Synthesis Polymerases and Proliferating Cell Nuclear Antigen
J.Biol.Chem., 284, 2009
1IH7
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BU of 1ih7 by Molmil
High-Resolution Structure of Apo RB69 DNA Polymerase
Descriptor: DNA POLYMERASE, GUANOSINE, POTASSIUM ION
Authors:Franklin, M.C, Wang, J, Steitz, T.A.
Deposit date:2001-04-18
Release date:2001-06-13
Last modified:2023-08-16
Method:X-RAY DIFFRACTION (2.21 Å)
Cite:Structure of the Replicating Complex of a Pol alpha Family DNA Polymerase
Cell(Cambridge,Mass.), 105, 2001
1IG9
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Structure of the Replicating Complex of a Pol Alpha Family DNA Polymerase
Descriptor: 5'-D(*AP*CP*AP*GP*GP*TP*AP*AP*GP*CP*AP*GP*TP*CP*CP*GP*CP*G)-3', 5'-D(*GP*CP*GP*GP*AP*CP*TP*GP*CP*TP*TP*AP*CP*(DOC))-3', CALCIUM ION, ...
Authors:Franklin, M.C, Wang, J, Steitz, T.A.
Deposit date:2001-04-17
Release date:2001-06-11
Last modified:2023-08-16
Method:X-RAY DIFFRACTION (2.6 Å)
Cite:Structure of the Replicating Complex of a Pol Alpha Family DNA Polymerase
Cell(Cambridge,Mass.), 105, 2001
3F1W
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Crystal structure of a mutant proliferating cell nuclear antigen that blocks translesion synthesis
Descriptor: Proliferating cell nuclear antigen
Authors:Freudenthal, B.D, Ramaswamy, S, Washington, M.T.
Deposit date:2008-10-28
Release date:2008-12-23
Last modified:2023-09-06
Method:X-RAY DIFFRACTION (2.901 Å)
Cite:Structure of a Mutant Form of Proliferating Cell Nuclear Antigen That Blocks Translesion DNA Synthesis.
Biochemistry, 47, 2008
1RXW
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Crystal structure of A. fulgidus FEN-1 bound to DNA
Descriptor: 5'-d(*C*pG*pA*pT*pG*pC*pT*pA)-3', 5'-d(*T*pA*pG*pC*pA*pT*pC*pG*pG)-3', Flap structure-specific endonuclease
Authors:Chapados, B.R, Hosfield, D.J, Han, S, Qiu, J, Yelent, B, Shen, B, Tainer, J.A.
Deposit date:2003-12-18
Release date:2004-01-27
Last modified:2023-08-23
Method:X-RAY DIFFRACTION (2 Å)
Cite:Structural Basis for FEN-1 Substrate Specificity and PCNA-Mediated Activation in DNA Replication and Repair
Cell(Cambridge,Mass.), 116, 2004
8E84
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Human PCNA mutant- C148S
Descriptor: Proliferating cell nuclear antigen
Authors:Magrino, J, Page, B, Gaubitz, C, Kelch, B.A.
Deposit date:2022-08-25
Release date:2023-04-12
Last modified:2023-10-25
Method:X-RAY DIFFRACTION (3.1 Å)
Cite:A thermosensitive PCNA allele underlies an ataxia-telangiectasia-like disorder.
J.Biol.Chem., 299, 2023
3LX2
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Crystal Structure analysis of PCNA from Thermococcus kodakaraensis tk0582
Descriptor: DNA polymerase sliding clamp 2, SULFATE ION
Authors:Ladner, J.E, Kelman, Z, Pan, M.
Deposit date:2010-02-24
Release date:2011-01-26
Last modified:2024-02-21
Method:X-RAY DIFFRACTION (2.4 Å)
Cite:Crystal structures of two active proliferating cell nuclear antigens (PCNAs) encoded by Thermococcus kodakaraensis.
Proc.Natl.Acad.Sci.USA, 108, 2011
3LX1
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Crystal Structure analysis of PCNA1 from Thermococcus kodakaraensis tk0535
Descriptor: DNA polymerase sliding clamp 1, SULFATE ION
Authors:Ladner, J.E, Kelman, Z, Pan, M.
Deposit date:2010-02-24
Release date:2011-01-26
Last modified:2024-02-21
Method:X-RAY DIFFRACTION (2 Å)
Cite:Crystal structures of two active proliferating cell nuclear antigens (PCNAs) encoded by Thermococcus kodakaraensis.
Proc.Natl.Acad.Sci.USA, 108, 2011
1UD9
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BU of 1ud9 by Molmil
Crystal Structure of Proliferating Cell Nuclear Antigen (PCNA) Homolog From Sulfolobus tokodaii
Descriptor: DNA polymerase sliding clamp A, ZINC ION
Authors:Tanabe, E, Yasutake, Y, Tanaka, Y, Yao, M, Tsumoto, K, Kumagai, I, Tanaka, I.
Deposit date:2003-04-28
Release date:2004-06-15
Last modified:2023-12-27
Method:X-RAY DIFFRACTION (1.68 Å)
Cite:Crystal Structure of Proliferating Cell Nuclear Antigen (PCNA) Homolog From Sulfolobus tokodaii
To be published
1S32
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BU of 1s32 by Molmil
Molecular Recognition of the Nucleosomal 'Supergroove'
Descriptor: 2-(2-CARBAMOYLMETHOXY-ETHOXY)-ACETAMIDE, 3-AMINO-(DIMETHYLPROPYLAMINE), 4-AMINO-(1-METHYLIMIDAZOLE)-2-CARBOXYLIC ACID, ...
Authors:Edayathumangalam, R.S, Weyermann, P, Gottesfeld, J.M, Dervan, P.B, Luger, K.
Deposit date:2004-01-12
Release date:2004-05-11
Last modified:2023-11-15
Method:X-RAY DIFFRACTION (2.05 Å)
Cite:Molecular Recognition of the Nucleosomal 'Supergroove'
Proc.Natl.Acad.Sci.USA, 101, 2004
1RXV
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BU of 1rxv by Molmil
Crystal Structure of A. Fulgidus FEN-1 bound to DNA
Descriptor: 5'-d(*T*pA*pG*pC*pA*pT*pC*pG*pG), Flap structure-specific endonuclease
Authors:Chapados, B.R, Hosfield, D.J, Han, S, Qiu, J, Yelent, B, Shen, B, Tainer, J.A.
Deposit date:2003-12-18
Release date:2004-01-27
Last modified:2024-04-03
Method:X-RAY DIFFRACTION (2.5 Å)
Cite:Structural Basis for FEN-1 Substrate Specificity and PCNA-Mediated Activation in DNA Replication and Repair
Cell(Cambridge,Mass.), 116, 2004
1U7B
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BU of 1u7b by Molmil
Crystal structure of hPCNA bound to residues 331-350 of the flap endonuclease-1 (FEN1)
Descriptor: Proliferating cell nuclear antigen, SRQGSTQGRLDDFFKVTGSL peptide of Flap endonuclease-1
Authors:Bruning, J.B, Shamoo, Y.
Deposit date:2004-08-03
Release date:2004-12-14
Last modified:2023-11-29
Method:X-RAY DIFFRACTION (1.88 Å)
Cite:Structural and Thermodynamic Analysis of Human PCNA with Peptides Derived from DNA Polymerase-delta p66 Subunit and Flap Endonuclease-1.
Structure, 12, 2004
8Q7I
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BU of 8q7i by Molmil
PCNA from Chaetomium thermophilum in complex with Fen1 peptide
Descriptor: Flap endonuclease 1, Proliferating cell nuclear antigen, SODIUM ION
Authors:Alphey, M.S, Wolford, C.B, MacNeill, S.A.
Deposit date:2023-08-16
Release date:2023-12-13
Last modified:2024-01-24
Method:X-RAY DIFFRACTION (1.95 Å)
Cite:Canonical binding of Chaetomium thermophilum DNA polymerase delta / zeta subunit PolD3 and flap endonuclease Fen1 to PCNA.
Front Mol Biosci, 10, 2023
1U76
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BU of 1u76 by Molmil
Crystal structure of hPCNA bound to residues 452-466 of the DNA polymerase-delta-p66 subunit
Descriptor: KANRQVSITGFFQRK peptide from DNA polymerase delta subunit 3, Proliferating cell nuclear antigen
Authors:Bruning, J.B, Shamoo, Y.
Deposit date:2004-08-02
Release date:2004-12-14
Last modified:2023-08-23
Method:X-RAY DIFFRACTION (2.6 Å)
Cite:Structural and Thermodynamic Analysis of Human PCNA with Peptides Derived from DNA Polymerase-delta p66 Subunit and Flap Endonuclease-1.
Structure, 12, 2004
6T7Y
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BU of 6t7y by Molmil
Structure of PCNA bound to cPIP motif of DP2 from P. abyssi
Descriptor: DNA polymerase sliding clamp, cPIP motif from the DP2 large subunit of PolD
Authors:Madru, C, Raia, P, Hugonneau Beaufet, I, Delarue, M, Carroni, M, Sauguet, L.
Deposit date:2019-10-23
Release date:2020-03-04
Last modified:2024-01-24
Method:X-RAY DIFFRACTION (2.7 Å)
Cite:Structural basis for the increased processivity of D-family DNA polymerases in complex with PCNA.
Nat Commun, 11, 2020
5E0U
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BU of 5e0u by Molmil
Human PCNA variant (S228I) complexed with p21 at 1.9 Angstroms
Descriptor: Cyclin-dependent kinase inhibitor 1, Proliferating cell nuclear antigen
Authors:Duffy, C.M, Hilbert, B.J, Kelch, B.A.
Deposit date:2015-09-29
Release date:2016-04-20
Last modified:2023-09-27
Method:X-RAY DIFFRACTION (1.93 Å)
Cite:A Disease-Causing Variant in PCNA Disrupts a Promiscuous Protein Binding Site.
J.Mol.Biol., 428, 2016
5E0V
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BU of 5e0v by Molmil
Human PCNA variant (S228I) complexed with FEN1 at 2.1 Angstroms
Descriptor: Flap endonuclease 1, Proliferating cell nuclear antigen
Authors:Duffy, C.M, Hilbert, B.J, Kelch, B.A.
Deposit date:2015-09-29
Release date:2016-04-20
Last modified:2023-09-27
Method:X-RAY DIFFRACTION (2.074 Å)
Cite:A Disease-Causing Variant in PCNA Disrupts a Promiscuous Protein Binding Site.
J.Mol.Biol., 428, 2016
6EEC
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BU of 6eec by Molmil
Mycobacterium tuberculosis RNAP promoter unwinding intermediate complex with RbpA/CarD and AP3 promoter captured by Corallopyronin
Descriptor: DNA (63-MER), DNA (65-MER), DNA-directed RNA polymerase subunit alpha, ...
Authors:Darst, S.A, Campbell, E.A, Boyaci Selcuk, H, Chen, J.
Deposit date:2018-08-13
Release date:2018-11-21
Last modified:2024-03-13
Method:ELECTRON MICROSCOPY (3.55 Å)
Cite:Structures of an RNA polymerase promoter melting intermediate elucidate DNA unwinding.
Nature, 565, 2019
6EDT
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BU of 6edt by Molmil
Mycobacterium tuberculosis RNAP open promoter complex with RbpA/CarD and AP3 promoter
Descriptor: DNA (65-MER), DNA-directed RNA polymerase subunit alpha, DNA-directed RNA polymerase subunit beta, ...
Authors:Darst, S.A, Campbell, E.A, Boyaci Selcuk, H, Chen, J.
Deposit date:2018-08-10
Release date:2018-11-21
Last modified:2024-03-13
Method:ELECTRON MICROSCOPY
Cite:Structures of an RNA polymerase promoter melting intermediate elucidate DNA unwinding.
Nature, 565, 2019
6GAV
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BU of 6gav by Molmil
Extremely 'open' clamp structure of DNA gyrase: role of the Corynebacteriales GyrB specific insert
Descriptor: 2-(N-MORPHOLINO)-ETHANESULFONIC ACID, DNA gyrase subunit B,DNA gyrase subunit A
Authors:Petrella, S, Capton, E, Alzari, P.M, Aubry, A, MAyer, C.
Deposit date:2018-04-12
Release date:2019-02-20
Last modified:2024-01-17
Method:X-RAY DIFFRACTION (2.6 Å)
Cite:Overall Structures of Mycobacterium tuberculosis DNA Gyrase Reveal the Role of a Corynebacteriales GyrB-Specific Insert in ATPase Activity.
Structure, 27, 2019
6GAU
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BU of 6gau by Molmil
Extremely 'open' clamp structure of DNA gyrase: role of the Corynebacteriales GyrB specific insert
Descriptor: DNA gyrase subunit B,DNA gyrase subunit A, MAGNESIUM ION, PHOSPHOAMINOPHOSPHONIC ACID-ADENYLATE ESTER
Authors:Petrella, S, Capton, E, Alzari, P.M, Aubry, A, Mayer, C.
Deposit date:2018-04-12
Release date:2019-02-20
Last modified:2024-01-17
Method:X-RAY DIFFRACTION (3.3 Å)
Cite:Overall Structures of Mycobacterium tuberculosis DNA Gyrase Reveal the Role of a Corynebacteriales GyrB-Specific Insert in ATPase Activity.
Structure, 27, 2019
6AIG
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BU of 6aig by Molmil
Crystal structure of PCNA1 from Aeropyrum pernix
Descriptor: DNA polymerase sliding clamp 1
Authors:Yamauchi, T, Kikuchi, M, Tsunoda, M.
Deposit date:2018-08-23
Release date:2018-09-26
Last modified:2023-11-29
Method:X-RAY DIFFRACTION (2 Å)
Cite:Crystal structure of PCNA1 from Aeropyrum pernix
To Be Published
6C06
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BU of 6c06 by Molmil
Mycobacterium tuberculosis RNAP Holo/RbpA/Fidaxomicin
Descriptor: DNA-directed RNA polymerase subunit alpha, DNA-directed RNA polymerase subunit beta, DNA-directed RNA polymerase subunit beta', ...
Authors:Darst, S.A, Campbell, E.A, Boyaci Selcuk, H, Chen, J, Lilic, M.
Deposit date:2017-12-27
Release date:2018-03-28
Last modified:2024-03-13
Method:ELECTRON MICROSCOPY (5.15 Å)
Cite:Fidaxomicin jamsMycobacterium tuberculosisRNA polymerase motions needed for initiation via RbpA contacts.
Elife, 7, 2018

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數據於2024-10-09公開中

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