8ET7
| Cryo-EM structure of the organic cation transporter 1 in complex with diphenhydramine | Descriptor: | 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, N-[2-(BENZHYDRYLOXY)ETHYL]-N,N-DIMETHYLAMINE, OCT1 | Authors: | Suo, Y, Wright, N.J, Lee, S.-Y. | Deposit date: | 2022-10-16 | Release date: | 2023-05-31 | Last modified: | 2023-08-02 | Method: | ELECTRON MICROSCOPY (3.77 Å) | Cite: | Molecular basis of polyspecific drug and xenobiotic recognition by OCT1 and OCT2. Nat.Struct.Mol.Biol., 30, 2023
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8ET8
| Cryo-EM structure of the organic cation transporter 1 in complex with verapamil | Descriptor: | (2S)-2-(3,4-dimethoxyphenyl)-5-{[2-(3,4-dimethoxyphenyl)ethyl](methyl)amino}-2-(propan-2-yl)pentanenitrile, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, OCT1 | Authors: | Suo, Y, Wright, N.J, Lee, S.-Y. | Deposit date: | 2022-10-16 | Release date: | 2023-05-31 | Last modified: | 2023-08-02 | Method: | ELECTRON MICROSCOPY (3.45 Å) | Cite: | Molecular basis of polyspecific drug and xenobiotic recognition by OCT1 and OCT2. Nat.Struct.Mol.Biol., 30, 2023
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8ET9
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8ET6
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4GBY
| The structure of the MFS (major facilitator superfamily) proton:xylose symporter XylE bound to D-xylose | Descriptor: | D-xylose-proton symporter, beta-D-xylopyranose, nonyl beta-D-glucopyranoside | Authors: | Sun, L.F, Zeng, X, Yan, C.Y, Yan, N. | Deposit date: | 2012-07-28 | Release date: | 2012-10-17 | Last modified: | 2024-02-28 | Method: | X-RAY DIFFRACTION (2.808 Å) | Cite: | Crystal structure of a bacterial homologue of glucose transporters GLUT1-4. Nature, 490, 2012
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4GBZ
| The structure of the MFS (major facilitator superfamily) proton:xylose symporter XylE bound to D-glucose | Descriptor: | D-xylose-proton symporter, beta-D-glucopyranose, nonyl beta-D-glucopyranoside | Authors: | Sun, L.F, Zeng, X, Yan, C.Y, Yan, N. | Deposit date: | 2012-07-28 | Release date: | 2012-10-17 | Last modified: | 2024-02-28 | Method: | X-RAY DIFFRACTION (2.894 Å) | Cite: | Crystal structure of a bacterial homologue of glucose transporters GLUT1-4. Nature, 490, 2012
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4GC0
| The structure of the MFS (major facilitator superfamily) proton:xylose symporter XylE bound to 6-bromo-6-deoxy-D-glucose | Descriptor: | 6-bromo-6-deoxy-beta-D-glucopyranose, D-xylose-proton symporter, nonyl beta-D-glucopyranoside | Authors: | Yan, N, Sun, L.F, Zeng, X, Yan, C.Y. | Deposit date: | 2012-07-28 | Release date: | 2012-10-17 | Last modified: | 2023-09-13 | Method: | X-RAY DIFFRACTION (2.6 Å) | Cite: | Crystal structure of a bacterial homologue of glucose transporters GLUT1-4. Nature, 490, 2012
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8FVZ
| PiPT Y150A | Descriptor: | CITRATE ANION, PHOSPHATE ION, Phosphate transporter | Authors: | Gupta, M, Finer-Moore, J, Stroud, R.M. | Deposit date: | 2023-01-20 | Release date: | 2024-01-03 | Method: | X-RAY DIFFRACTION (3.1 Å) | Cite: | Roles of PiPT residues in phosphate binding and transport tested by mutagenesis To be published
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4YB9
| Crystal structure of the Bovine Fructose transporter GLUT5 in an open inward-facing conformation | Descriptor: | Solute carrier family 2, facilitated glucose transporter member 5 | Authors: | Verdon, G, Kang, H.J, Iwata, S, Drew, D. | Deposit date: | 2015-02-18 | Release date: | 2015-10-14 | Last modified: | 2024-05-01 | Method: | X-RAY DIFFRACTION (3.2 Å) | Cite: | Structure and mechanism of the mammalian fructose transporter GLUT5. Nature, 526, 2015
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4YBQ
| Rat GLUT5 with Fv in the outward-open form | Descriptor: | Solute carrier family 2, facilitated glucose transporter member 5, antibody Fv fragment heavy chain, ... | Authors: | Nomura, N, Shimamura, T, Iwata, S. | Deposit date: | 2015-02-19 | Release date: | 2015-10-07 | Last modified: | 2023-11-08 | Method: | X-RAY DIFFRACTION (3.27 Å) | Cite: | Structure and mechanism of the mammalian fructose transporter GLUT5 Nature, 526, 2015
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4ZWB
| Crystal structure of maltose-bound human GLUT3 in the outward-occluded conformation at 2.4 angstrom | Descriptor: | Solute carrier family 2, facilitated glucose transporter member 3, alpha-D-glucopyranose-(1-4)-alpha-D-glucopyranose | Authors: | Deng, D, Sun, P.C, Yan, C.Y, Yan, N. | Deposit date: | 2015-05-19 | Release date: | 2015-07-22 | Last modified: | 2023-11-08 | Method: | X-RAY DIFFRACTION (2.4 Å) | Cite: | Molecular basis of ligand recognition and transport by glucose transporters Nature, 526, 2015
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4ZWC
| Crystal structure of maltose-bound human GLUT3 in the outward-open conformation at 2.6 angstrom | Descriptor: | (2R)-2,3-dihydroxypropyl (9Z)-octadec-9-enoate, Solute carrier family 2, facilitated glucose transporter member 3, ... | Authors: | Deng, D, Sun, P.C, Yan, C.Y, Yan, N. | Deposit date: | 2015-05-19 | Release date: | 2015-07-22 | Last modified: | 2023-11-08 | Method: | X-RAY DIFFRACTION (2.6 Å) | Cite: | Molecular basis of ligand recognition and transport by glucose transporters Nature, 526, 2015
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4ZW9
| Crystal structure of human GLUT3 bound to D-glucose in the outward-occluded conformation at 1.5 angstrom | Descriptor: | (2R)-2,3-dihydroxypropyl (9Z)-octadec-9-enoate, Solute carrier family 2, facilitated glucose transporter member 3, ... | Authors: | Deng, D, Sun, P.C, Yan, C.Y, Yan, N. | Deposit date: | 2015-05-19 | Release date: | 2015-07-22 | Last modified: | 2023-11-08 | Method: | X-RAY DIFFRACTION (1.502 Å) | Cite: | Molecular basis of ligand recognition and transport by glucose transporters Nature, 526, 2015
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4JA3
| Partially occluded inward open conformation of the xylose transporter XylE from E. coli | Descriptor: | CADMIUM ION, D-xylose-proton symporter, LUTETIUM (III) ION | Authors: | Quistgaard, E.M, Low, C, Moberg, P, Tresaugues, L, Nordlund, P. | Deposit date: | 2013-02-18 | Release date: | 2013-05-01 | Last modified: | 2024-02-28 | Method: | X-RAY DIFFRACTION (3.8 Å) | Cite: | Structural basis for substrate transport in the GLUT-homology family of monosaccharide transporters. Nat.Struct.Mol.Biol., 20, 2013
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4JA4
| Inward open conformation of the xylose transporter XylE from E. coli | Descriptor: | CADMIUM ION, D-xylose-proton symporter | Authors: | Quistgaard, E.M, Low, C, Moberg, P, Tresaugues, L, Nordlund, P. | Deposit date: | 2013-02-18 | Release date: | 2013-05-01 | Last modified: | 2024-02-28 | Method: | X-RAY DIFFRACTION (4.2 Å) | Cite: | Structural basis for substrate transport in the GLUT-homology family of monosaccharide transporters. Nat.Struct.Mol.Biol., 20, 2013
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8WJH
| Cryo-EM structure of OAT4 | Descriptor: | CHLORIDE ION, Solute carrier family 22 member 11 | Authors: | Qian, H.W, He, J.J. | Deposit date: | 2023-09-26 | Release date: | 2024-08-28 | Last modified: | 2024-09-04 | Method: | ELECTRON MICROSCOPY (3.1 Å) | Cite: | Structural basis for the transport and substrate selection of human urate transporter 1. Cell Rep, 43, 2024
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9J2N
| Cryo-EM structure of the human glucose transporter, GLUT7 in outward-facing open conformation | Descriptor: | 2-acetamido-2-deoxy-beta-D-glucopyranose, Solute carrier family 2, facilitated glucose transporter member 7 | Authors: | Lee, S.S, Kim, S, Jin, M.S. | Deposit date: | 2024-08-07 | Release date: | 2024-09-25 | Last modified: | 2024-10-09 | Method: | ELECTRON MICROSCOPY (3.3 Å) | Cite: | Cryo-EM structure of the human glucose transporter GLUT7. Biochem.Biophys.Res.Commun., 738, 2024
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8Y66
| Cryo-EM structure of human urate transporter GLUT9 bound to inhibitor apigenin | Descriptor: | 5,7-dihydroxy-2-(4-hydroxyphenyl)-4H-chromen-4-one, Solute carrier family 2, facilitated glucose transporter member 9 | Authors: | Pan, X.J, Shen, Z.L, Xu, L, Huang, G.X.Y. | Deposit date: | 2024-02-01 | Release date: | 2024-06-19 | Method: | ELECTRON MICROSCOPY (3.28 Å) | Cite: | Structural basis for urate recognition and apigenin inhibition of human GLUT9. Nat Commun, 15, 2024
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8Y65
| Cryo-EM structure of human urate transporter GLUT9 bound to substrate urate | Descriptor: | Solute carrier family 2, facilitated glucose transporter member 9, URIC ACID | Authors: | Pan, X.J, Shen, Z.L, Xu, L, Huang, G.X.Y. | Deposit date: | 2024-02-01 | Release date: | 2024-06-19 | Method: | ELECTRON MICROSCOPY (3.51 Å) | Cite: | Structural basis for urate recognition and apigenin inhibition of human GLUT9. Nat Commun, 15, 2024
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9G11
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8SC3
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8SC4
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8SDU
| Structure of rat organic anion transporter 1 (OAT1) | Descriptor: | Solute carrier family 22 member 6 | Authors: | Dou, T, Jiang, J. | Deposit date: | 2023-04-07 | Release date: | 2023-10-18 | Last modified: | 2024-10-16 | Method: | ELECTRON MICROSCOPY (2.05 Å) | Cite: | The substrate and inhibitor binding mechanism of polyspecific transporter OAT1 revealed by high-resolution cryo-EM. Nat.Struct.Mol.Biol., 30, 2023
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8SC1
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8SC2
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