8GGG
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![BU of 8ggg by Molmil](/molmil-images/mine/8ggg) | RNase A-Adenosine 5'-Hexaphosphate (RNaseA.p6A) | Descriptor: | GLYCEROL, Ribonuclease pancreatic, adenosine 5'-hexaphosphate | Authors: | Park, G, Cummins, C. | Deposit date: | 2023-03-08 | Release date: | 2024-03-13 | Method: | X-RAY DIFFRACTION (1.86 Å) | Cite: | Experimental and Computational Studies for the Effect of Lengthening the Phosphate Chain of Nucleotide on the RNase A Inhibitiors. To Be Published
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5JLG
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![BU of 5jlg by Molmil](/molmil-images/mine/5jlg) | The X-ray structure of the adduct formed in the reaction between bovine pancreatic ribonuclease and compound I, a piano-stool organometallic Ru(II) arene compound containing an O,S-chelating ligand | Descriptor: | DIMETHYL SULFOXIDE, RUTHENIUM ION, Ribonuclease pancreatic, ... | Authors: | Ferraro, G, Merlino, A. | Deposit date: | 2016-04-27 | Release date: | 2016-08-03 | Last modified: | 2024-01-10 | Method: | X-RAY DIFFRACTION (1.79 Å) | Cite: | Unusual mode of protein binding by a cytotoxic pi-arene ruthenium(ii) piano-stool compound containing an O,S-chelating ligand. Dalton Trans, 45, 2016
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5JMG
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![BU of 5jmg by Molmil](/molmil-images/mine/5jmg) | X-ray structure of the complex between bovine pancreatic ribonuclease and pentachlorocarbonyliridate(III) (4 days of soaking) | Descriptor: | CARBON MONOXIDE, CHLORIDE ION, IRIDIUM ION, ... | Authors: | Caterino, M, Petruk, A.A, Vergara, A, Ferraro, G, Merlino, A. | Deposit date: | 2016-04-29 | Release date: | 2016-07-27 | Last modified: | 2024-01-10 | Method: | X-RAY DIFFRACTION (1.85 Å) | Cite: | Mapping the protein-binding sites for iridium(iii)-based CO-releasing molecules. Dalton Trans, 45, 2016
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8FHM
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![BU of 8fhm by Molmil](/molmil-images/mine/8fhm) | RNase A-Uridine 5'-Hexaphosphate (RNaseA.p6U) | Descriptor: | 5'-O-[(S)-hydroxy{[(S)-hydroxy{[(R)-hydroxy{[(S)-hydroxy{[(R)-hydroxy(phosphonooxy)phosphoryl]oxy}phosphoryl]oxy}phosphoryl]oxy}phosphoryl]oxy}phosphoryl]uridine, Ribonuclease pancreatic | Authors: | Park, G, Cummins, C. | Deposit date: | 2022-12-14 | Release date: | 2023-12-20 | Method: | SOLUTION SCATTERING (1.79 Å), X-RAY DIFFRACTION | Cite: | Experimental and Computational Studies for the Effect of Lengthening the Phosphate Chain of Nucleotide on the RNase A inhibitors. To Be Published
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8GC9
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![BU of 8gc9 by Molmil](/molmil-images/mine/8gc9) | RNase A-Uridine 5'-Heptaphosphate (RNase A.p7U) | Descriptor: | Ribonuclease pancreatic, uridine 5'-heptaphosphate | Authors: | Park, G, Cummins, C. | Deposit date: | 2023-03-01 | Release date: | 2024-03-06 | Method: | X-RAY DIFFRACTION (1.85 Å) | Cite: | Experimental and Computational Studies for the Effect of Lengthening the Phosphate Chain of Nucleotide on the RNase A Inhibitors. To Be Published
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7Z6G
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![BU of 7z6g by Molmil](/molmil-images/mine/7z6g) | |
7Z6D
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![BU of 7z6d by Molmil](/molmil-images/mine/7z6d) | |
5JML
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![BU of 5jml by Molmil](/molmil-images/mine/5jml) | X-ray structure of the complex between bovine pancreatic ribonuclease and penthachlorocarbonyliridate(III) (2 months of soaking) | Descriptor: | CARBON MONOXIDE, CHLORIDE ION, IRIDIUM ION, ... | Authors: | Caterino, M, Petruk, A.A, Vergara, A, Ferraro, G, Merlino, A. | Deposit date: | 2016-04-29 | Release date: | 2016-07-27 | Last modified: | 2024-01-10 | Method: | X-RAY DIFFRACTION (2.29 Å) | Cite: | Mapping the protein-binding sites for iridium(iii)-based CO-releasing molecules. Dalton Trans, 45, 2016
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8RSA
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![BU of 8rsa by Molmil](/molmil-images/mine/8rsa) | |
8RAT
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![BU of 8rat by Molmil](/molmil-images/mine/8rat) | |
8AF0
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![BU of 8af0 by Molmil](/molmil-images/mine/8af0) | Crystal structure of human angiogenin and RNA duplex | Descriptor: | Angiogenin, GLYCEROL, RNA (5'-R(*GP*CP*CP*CP*GP*CP*CP*UP*GP*UP*CP*AP*CP*GP*CP*GP*GP*GP*C)-3') | Authors: | Sievers, K, Ficner, R. | Deposit date: | 2022-07-15 | Release date: | 2022-09-14 | Last modified: | 2024-01-31 | Method: | X-RAY DIFFRACTION (2.43 Å) | Cite: | Structure of angiogenin dimer bound to double-stranded RNA. Acta Crystallogr.,Sect.F, 78, 2022
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4G90
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![BU of 4g90 by Molmil](/molmil-images/mine/4g90) | Crystal structure of Ribonuclease A in complex with 5e | Descriptor: | 1-{[1-(alpha-L-arabinofuranosyl)-1H-1,2,3-triazol-4-yl]methyl}-5-fluoro-2,4-dioxo-1,2,3,4-tetrahydropyrimidine, Ribonuclease pancreatic | Authors: | Chatzileontiadou, D.S.M, Kantsadi, A.L, Leonidas, D.D. | Deposit date: | 2012-07-23 | Release date: | 2012-11-21 | Last modified: | 2023-09-13 | Method: | X-RAY DIFFRACTION (1.9 Å) | Cite: | Triazole pyrimidine nucleosides as inhibitors of Ribonuclease A. Synthesis, biochemical, and structural evaluation. Bioorg.Med.Chem., 20, 2012
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4G8V
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![BU of 4g8v by Molmil](/molmil-images/mine/4g8v) | Crystal structure of Ribonuclease A in complex with 5a | Descriptor: | 1-{[1-(alpha-L-arabinofuranosyl)-1H-1,2,3-triazol-4-yl]methyl}-2,4-dioxo-1,2,3,4-tetrahydropyrimidine, Ribonuclease pancreatic | Authors: | Chatzileontiadou, D.S.M, Kantsadi, A.L, Leonidas, D.D. | Deposit date: | 2012-07-23 | Release date: | 2012-11-21 | Last modified: | 2023-09-13 | Method: | X-RAY DIFFRACTION (1.7 Å) | Cite: | Triazole pyrimidine nucleosides as inhibitors of Ribonuclease A. Synthesis, biochemical, and structural evaluation. Bioorg.Med.Chem., 20, 2012
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3U01
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![BU of 3u01 by Molmil](/molmil-images/mine/3u01) | Crystal structure of onconase double mutant C30A/C75A at 1.12 A resolution | Descriptor: | ACETATE ION, Protein P-30, SULFATE ION | Authors: | Kurpiewska, K, Torrent, G, Ribo, M, Vilanova, M, Loch, J, Lewinski, K. | Deposit date: | 2011-09-28 | Release date: | 2011-12-21 | Last modified: | 2023-09-13 | Method: | X-RAY DIFFRACTION (1.12 Å) | Cite: | Investigating the effects of double mutation C30A/C75A on onconase structure: Studies at atomic resolution. Biopolymers, 101, 2014
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3SNF
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![BU of 3snf by Molmil](/molmil-images/mine/3snf) | Onconase, atomic resolution crystal structure | Descriptor: | ACETATE ION, Protein P-30, SULFATE ION | Authors: | Holloway, D.E, Singh, U.P, Shogen, K, Acharya, K.R. | Deposit date: | 2011-06-29 | Release date: | 2011-10-05 | Last modified: | 2023-09-13 | Method: | X-RAY DIFFRACTION (1.1 Å) | Cite: | Crystal structure of Onconase at 1.1 angstrom resolution--insights into substrate binding and collective motion. Febs J., 278, 2011
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4X09
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![BU of 4x09 by Molmil](/molmil-images/mine/4x09) | Structure of human RNase 6 in complex with sulphate anions | Descriptor: | GLYCEROL, Ribonuclease K6, SULFATE ION | Authors: | Prats-Ejarque, G, Arranz-Trullen, J, Blanco, J.A, Pulido, D, Moussaoui, M, Boix, E. | Deposit date: | 2014-11-21 | Release date: | 2016-04-06 | Last modified: | 2024-01-10 | Method: | X-RAY DIFFRACTION (1.722 Å) | Cite: | The first crystal structure of human RNase 6 reveals a novel substrate-binding and cleavage site arrangement. Biochem.J., 473, 2016
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4YGW
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![BU of 4ygw by Molmil](/molmil-images/mine/4ygw) | RNase S in complex with stabilized S peptide | Descriptor: | 1-hydroxypropan-2-one, Ribonuclease A C2, S-peptide: ACE-LYS-GLU-THR-ALA-ALA-HCS-LYS-PHE-GLU-HCS-GLN-HIS-MET-ASP-SER, ... | Authors: | Assem, N, Ferreira, D, Wolan, D.W, Dawson, P.E. | Deposit date: | 2015-02-26 | Release date: | 2015-07-01 | Last modified: | 2024-04-03 | Method: | X-RAY DIFFRACTION (2.18 Å) | Cite: | Acetone-Linked Peptides: A Convergent Approach for Peptide Macrocyclization and Labeling. Angew.Chem.Int.Ed.Engl., 54, 2015
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3SRN
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![BU of 3srn by Molmil](/molmil-images/mine/3srn) | STRUCTURAL CHANGES THAT ACCOMPANY THE REDUCED CATALYTIC EFFICIENCY OF TWO SEMISYNTHETIC RIBONUCLEASE ANALOGS | Descriptor: | RIBONUCLEASE A, SULFATE ION | Authors: | deMel, V.S.J, Martin, P.D, Doscher, M.S, Edwards, B.F.P. | Deposit date: | 1991-05-20 | Release date: | 1994-12-20 | Last modified: | 2019-08-14 | Method: | X-RAY DIFFRACTION (2 Å) | Cite: | Structural changes that accompany the reduced catalytic efficiency of two semisynthetic ribonuclease analogs. J.Biol.Chem., 267, 1992
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4WYZ
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![BU of 4wyz by Molmil](/molmil-images/mine/4wyz) | The crystal structure of the A109G mutant of RNase A in complex with 3'UMP | Descriptor: | 3'-URIDINEMONOPHOSPHATE, Ribonuclease pancreatic | Authors: | French, R.L, Gagne, D, Doucet, N, Simonovic, M. | Deposit date: | 2014-11-18 | Release date: | 2015-11-18 | Last modified: | 2019-12-25 | Method: | X-RAY DIFFRACTION (1.449 Å) | Cite: | Perturbation of the Conformational Dynamics of an Active-Site Loop Alters Enzyme Activity. Structure, 23, 2015
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4WYP
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![BU of 4wyp by Molmil](/molmil-images/mine/4wyp) | The crystal structure of the A109G mutant of RNase A in complex with 5'AMP | Descriptor: | ADENOSINE MONOPHOSPHATE, Ribonuclease pancreatic | Authors: | French, R.L, Gagne, D, Doucet, N, Simonovic, M. | Deposit date: | 2014-11-17 | Release date: | 2015-11-18 | Last modified: | 2023-09-27 | Method: | X-RAY DIFFRACTION (1.502 Å) | Cite: | Perturbation of the Conformational Dynamics of an Active-Site Loop Alters Enzyme Activity. Structure, 23, 2015
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4X08
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![BU of 4x08 by Molmil](/molmil-images/mine/4x08) | Structure of H128N/ECP mutant in complex with sulphate anions at 1.34 Angstroms. | Descriptor: | Eosinophil cationic protein, SULFATE ION | Authors: | Blanco, J.A, Garcia, J.M, Salazar, V.A, Sanchez, D, Moussauoi, M, Boix, E. | Deposit date: | 2014-11-21 | Release date: | 2015-10-07 | Last modified: | 2024-01-10 | Method: | X-RAY DIFFRACTION (1.34 Å) | Cite: | Structure of H128N/ECP mutant in complex with sulphate anions at 1.34 Angstroms. To Be Published
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4WYN
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![BU of 4wyn by Molmil](/molmil-images/mine/4wyn) | |
4ZZ4
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![BU of 4zz4 by Molmil](/molmil-images/mine/4zz4) | |
3U00
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![BU of 3u00 by Molmil](/molmil-images/mine/3u00) | Crystal structure of wild-type onconase at 1.65 A resolution | Descriptor: | PHOSPHATE ION, Protein P-30 | Authors: | Kurpiewska, K, Torrent, G, Ribo, M, Vilanova, M, Loch, J, Lewinski, K. | Deposit date: | 2011-09-28 | Release date: | 2011-12-21 | Last modified: | 2023-09-13 | Method: | X-RAY DIFFRACTION (1.65 Å) | Cite: | Crystal structure of wild-type onconase at 1.65 A resolution To be Published
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5ARL
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![BU of 5arl by Molmil](/molmil-images/mine/5arl) | |