3DJO

Bovine Seminal Ribonuclease uridine 2' phosphate complex

Summary for 3DJO

Entry DOI	10.2210/pdb3djo/pdb
Related	3DJP 3DJQ 3DJV 3DJX
Descriptor	Seminal ribonuclease, PHOSPHORIC ACID MONO-[2-(2,4-DIOXO-3,4-DIHYDRO-2H-PYRIMIDIN-1-YL)-4-HYDROXY-5-HYDROXYMETHYL-TETRAHYDRO-FURAN-3-YL] ESTER, ACETATE ION, ... (4 entities in total)
Functional Keywords	ribonuclease, hydrolase, allosteric enzyme, endonuclease, nuclease, secreted
Biological source	Bos taurus (Bovine)
Cellular location	Secreted: P00669
Total number of polymer chains	2
Total formula weight	28031.73
Authors	Dossi, K.,Leonidas, D.D.,Zographos, S.E.,Oikonomakos, N.G. (deposition date: 2008-06-24, release date: 2009-06-30, Last modification date: 2023-11-01)
Primary citation	Dossi, K.,Tsirkone, V.G.,Hayes, J.M.,Matousek, J.,Pouckova, P.,Soucek, J.,Zadinova, M.,Zographos, S.E.,Leonidas, D.D. Mapping the ribonucleolytic active site of bovine seminal ribonuclease. The binding of pyrimidinyl phosphonucleotide inhibitors Eur.J.Med.Chem., 44:4496-4508, 2009 Cited by PubMed: 19643512 DOI: 10.1016/j.ejmech.2009.06.039 PDB entries with the same primary citation
Experimental method	X-RAY DIFFRACTION (1.6 Å)

Structure validation