PDB: 5653 resultsInfo pagesStatus searchChemie searchBIRD

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7NQD	Prim-Pol Domain of CRISPR-associated Prim-Pol (CAPP) from Marinitoga sp. 1137 Descriptor: TPR_REGION domain-containing protein Authors: Li, A.W.H, Doherty, A.J. Deposit date: 2021-03-01 Release date: 2022-05-04 Last modified: 2024-06-19 Method: X-RAY DIFFRACTION (2.97 Å) Cite: Molecular basis for the initiation of DNA primer synthesis. Nature, 605, 2022
7NQF	Prim-Pol Domain of CRISPR-associated Prim-Pol (CAPP) from Marinitoga sp. 1137 with dsDNA Descriptor: COBALT (II) ION, DNA(CGTGDG), TPR_REGION domain-containing protein Authors: Li, A.W.H, Doherty, A.J. Deposit date: 2021-03-01 Release date: 2022-05-04 Last modified: 2024-01-31 Method: X-RAY DIFFRACTION (2.02 Å) Cite: Molecular basis for the initiation of DNA primer synthesis. Nature, 605, 2022
7NQE	Prim-Pol Domain of CRISPR-associated Prim-Pol (CAPP) from Marinitoga sp. 1137 with dGTP Descriptor: 1,2-ETHANEDIOL, 2'-DEOXYGUANOSINE-5'-TRIPHOSPHATE, MANGANESE (II) ION, ... Authors: Li, A.W.H, Doherty, A.J. Deposit date: 2021-03-01 Release date: 2022-05-04 Last modified: 2024-01-31 Method: X-RAY DIFFRACTION (1.28 Å) Cite: Molecular basis for the initiation of DNA primer synthesis. Nature, 605, 2022
6M4O	Cryo-EM structure of the monomeric SPT-ORMDL3 complex Descriptor: ORM1-like protein 3, PYRIDOXAL-5'-PHOSPHATE, Serine palmitoyltransferase 1, ... Authors: Li, S.S, Xie, T, Wang, L, Gong, X. Deposit date: 2020-03-08 Release date: 2021-02-10 Last modified: 2021-03-24 Method: ELECTRON MICROSCOPY (3.4 Å) Cite: Structural insights into the assembly and substrate selectivity of human SPT-ORMDL3 complex. Nat.Struct.Mol.Biol., 28, 2021
6M4N	Cryo-EM structure of the dimeric SPT-ORMDL3 complex Descriptor: ORM1-like protein 3, PYRIDOXAL-5'-PHOSPHATE, Serine palmitoyltransferase 1, ... Authors: Li, S.S, Xie, T, Wang, L, Gong, X. Deposit date: 2020-03-07 Release date: 2021-02-10 Last modified: 2021-03-24 Method: ELECTRON MICROSCOPY (3.8 Å) Cite: Structural insights into the assembly and substrate selectivity of human SPT-ORMDL3 complex. Nat.Struct.Mol.Biol., 28, 2021
5XZI	Crystal structure of the Zn-directed tetramer of the engineered cyt cb562 variant, AB5 Descriptor: CHLORIDE ION, HEME C, Soluble cytochrome b562, ... Authors: Song, W.J, Tezcan, F.A. Deposit date: 2017-07-12 Release date: 2017-12-20 Last modified: 2019-10-02 Method: X-RAY DIFFRACTION (2.65 Å) Cite: Importance of Scaffold Flexibility/Rigidity in the Design and Directed Evolution of Artificial Metallo-beta-lactamases. J. Am. Chem. Soc., 139, 2017
8RU8	A crystal form of a human CDK2-CDK7 chimera Descriptor: (3R,4R)-4-[[[7-[(phenylmethyl)amino]-3-propan-2-yl-pyrazolo[1,5-a]pyrimidin-5-yl]amino]methyl]piperidin-3-ol, Cyclin-dependent kinase 2 Authors: Mukherjee, M, Cleasby, A. Deposit date: 2024-01-30 Release date: 2024-06-26 Method: X-RAY DIFFRACTION (1.51 Å) Cite: Protein engineering enables a soakable crystal form of human CDK7 primed for high-throughput crystallography and structure-based drug design. Structure, 2024
5XZJ	Crystal structure of the Zn-directed tetramer of the engineered cyt cb562 variant, C96T/AB5 Descriptor: CHLORIDE ION, HEME C, Soluble cytochrome b562, ... Authors: Song, W.J, Tezcan, F.A. Deposit date: 2017-07-12 Release date: 2017-12-20 Last modified: 2022-03-23 Method: X-RAY DIFFRACTION (1.98 Å) Cite: Importance of Scaffold Flexibility/Rigidity in the Design and Directed Evolution of Artificial Metallo-beta-lactamases. J. Am. Chem. Soc., 139, 2017
5JKM	Binary crystal structure of positively and negatively supercharged variants Ftn(pos) and Ftn(neg) from human heavy chain ferritin (Mg acetate condition) Descriptor: FE (III) ION, Ferritin heavy chain, GLYCEROL, ... Authors: Kuenzle, M, Beck, T. Deposit date: 2016-04-26 Release date: 2016-10-26 Last modified: 2024-01-10 Method: X-RAY DIFFRACTION (1.8 Å) Cite: Binary Protein Crystals for the Assembly of Inorganic Nanoparticle Superlattices. J.Am.Chem.Soc., 138, 2016
5YKA	Crystal structure of the Kdo hydroxylase KdoO, a non-heme Fe(II) alphaketoglutarate dependent dioxygenase in complex with cobalt(II) Descriptor: ACETATE ION, CHLORIDE ION, COBALT (II) ION, ... Authors: Chung, H.S, Pemble, C.W, Joo, S.H, Raetz, C.R. Deposit date: 2017-10-12 Release date: 2018-09-05 Last modified: 2024-03-27 Method: X-RAY DIFFRACTION (1.448 Å) Cite: Biochemical and Structural Insights into an Fe(II)/ alpha-Ketoglutarate/O2-Dependent Dioxygenase, Kdo 3-Hydroxylase (KdoO). J. Mol. Biol., 430, 2018
7P3H	Peptide HC02 - Lanthanide Selectivity Engineered into Structurally Characterized Designed Coiled Coils Descriptor: Peptide HC02, TERBIUM(III) ION, ZINC ION Authors: White, S.A, Peacock, A.F.A. Deposit date: 2021-07-07 Release date: 2021-09-15 Last modified: 2024-05-01 Method: X-RAY DIFFRACTION (2.1 Å) Cite: Location-Dependent Lanthanide Selectivity Engineered into Structurally Characterized Designed Coiled Coils. Angew.Chem.Int.Ed.Engl., 60, 2021
4L5Y	Methylthioadenosine phosphorylase from Schistosoma mansoni in APO form Descriptor: PHOSPHATE ION, S-methyl-5'-thioadenosine phosphorylase Authors: Torini, J.R, DeMarco, R, Brandao-Neto, J, Pereira, H.M. Deposit date: 2013-06-11 Release date: 2014-06-11 Last modified: 2024-02-28 Method: X-RAY DIFFRACTION (2.0957 Å) Cite: Crystal Structure of Schistosoma mansoni Adenosine Phosphorylase/5'-Methylthioadenosine Phosphorylase and Its Importance on Adenosine Salvage Pathway. Plos Negl Trop Dis, 10, 2016
5YVZ	Crystal structure of the Kdo hydroxylase KdoO, a non-heme Fe(II) alphaketoglutarate dependent dioxygenase in complex with alphaketoglutarate and Fe(III) Descriptor: 2-OXOGLUTARIC ACID, ACETATE ION, FE (III) ION, ... Authors: Chung, H.S, Pemble, C.W, Joo, S.H, Raetz, C.R. Deposit date: 2017-11-28 Release date: 2018-09-05 Last modified: 2023-11-22 Method: X-RAY DIFFRACTION (1.6 Å) Cite: Biochemical and Structural Insights into an Fe(II)/ alpha-Ketoglutarate/O2-Dependent Dioxygenase, Kdo 3-Hydroxylase (KdoO). J. Mol. Biol., 430, 2018
5K0X	Crystal structure of the catalytic domain of the proto-oncogene tyrosine-protein kinase MER in complex with inhibitor UNC2541 Descriptor: (7S)-7-amino-N-[(4-fluorophenyl)methyl]-8-oxo-2,9,16,18,21-pentaazabicyclo[15.3.1]henicosa-1(21),17,19-triene-20-carboxamide, CHLORIDE ION, Tyrosine-protein kinase Mer Authors: McIver, A.L, Zhang, W, Liu, Q, Jiang, X, Stashko, M.A, Nichols, J, Miley, M.J, Norris-Drouin, J, Machius, M, DeRyckere, D, Wood, E, Graham, D.K, Earp, H.S, Kireev, D, Frye, S.V, Wang, X. Deposit date: 2016-05-17 Release date: 2017-02-22 Last modified: 2023-09-27 Method: X-RAY DIFFRACTION (2.231 Å) Cite: Discovery of Macrocyclic Pyrimidines as MerTK-Specific Inhibitors. ChemMedChem, 12, 2017
5K2E	Structure of NNQQNY from yeast prion Sup35 with zinc acetate determined by MicroED Descriptor: ACETIC ACID, Eukaryotic peptide chain release factor GTP-binding subunit, ZINC ION Authors: Rodriguez, J.A, Sawaya, M.R, Cascio, D, Eisenberg, D.S. Deposit date: 2016-05-18 Release date: 2016-09-14 Last modified: 2024-03-06 Method: ELECTRON CRYSTALLOGRAPHY (1 Å) Cite: Ab initio structure determination from prion nanocrystals at atomic resolution by MicroED. Proc.Natl.Acad.Sci.USA, 113, 2016
6NEF	Outer Membrane Cytochrome S Filament from Geobacter Sulfurreducens Descriptor: C-type cytochrome OmcS, HEME C, MAGNESIUM ION Authors: Filman, D.J, Marino, S.F, Ward, J.E, Yang, L, Mester, Z, Bullitt, E, Lovley, D.R, Strauss, M. Deposit date: 2018-12-17 Release date: 2019-07-03 Last modified: 2019-09-11 Method: ELECTRON MICROSCOPY (3.42 Å) Cite: Cryo-EM reveals the structural basis of long-range electron transport in a cytochrome-based bacterial nanowire. Commun Biol, 2, 2019
5ZKK	Crystal structure of Phosphoserine phosphatase from Entamoeba histolytica Descriptor: BETA-MERCAPTOETHANOL, DI(HYDROXYETHYL)ETHER, GLYCEROL, ... Authors: Kumari, P, Gourinath, S. Deposit date: 2018-03-24 Release date: 2019-04-03 Last modified: 2023-11-22 Method: X-RAY DIFFRACTION (2 Å) Cite: Structural and functional characterisation of phosphoserine phosphatase, that plays critical role in the oxidative stress response in the parasite Entamoeba histolytica. J.Struct.Biol., 206, 2019
6NNR	high-resolution structure of wild-type E. coli thymidylate synthase Descriptor: 10-PROPARGYL-5,8-DIDEAZAFOLIC ACID, 2'-deoxy-5'-uridylic acid, 4-(2-HYDROXYETHYL)-1-PIPERAZINE ETHANESULFONIC ACID, ... Authors: Stroud, R.M, Finer-Moore, J. Deposit date: 2019-01-15 Release date: 2019-01-30 Last modified: 2023-10-11 Method: X-RAY DIFFRACTION (1.05 Å) Cite: Mg2+ binds to the surface of thymidylate synthase and affects hydride transfer at the interior active site. J. Am. Chem. Soc., 135, 2013
5K2G	Structure of GNNQQNY from yeast prion Sup35 in space group P21 determined by MicroED Descriptor: Eukaryotic peptide chain release factor GTP-binding subunit Authors: Rodriguez, J.A, Sawaya, M.R, Cascio, D, Eisenberg, D.S. Deposit date: 2016-05-18 Release date: 2016-09-14 Last modified: 2024-03-06 Method: ELECTRON CRYSTALLOGRAPHY (1.1 Å) Cite: Ab initio structure determination from prion nanocrystals at atomic resolution by MicroED. Proc.Natl.Acad.Sci.USA, 113, 2016
7P9J	Prim-Pol Domain of CRISPR-associated Prim-Pol (CAPP) from Marinitoga sp. 1137 - Primer Initiation Complex Descriptor: 2'-deoxy-5'-O-[(R)-hydroxy{[(R)-hydroxy(phosphonooxy)phosphoryl]amino}phosphoryl]adenosine, COBALT (II) ION, GUANOSINE-5'-TRIPHOSPHATE, ... Authors: Li, A.W.H, Doherty, A.J. Deposit date: 2021-07-27 Release date: 2022-05-04 Last modified: 2024-01-31 Method: X-RAY DIFFRACTION (1.9 Å) Cite: Molecular basis for the initiation of DNA primer synthesis. Nature, 605, 2022
5MHH	Crystal structure of engineered human lipocalin 2 carrying p-boronophenylalanine at position 36 Descriptor: Neutrophil gelatinase-associated lipocalin, SULFATE ION Authors: Skerra, A, Eichinger, A. Deposit date: 2016-11-24 Release date: 2017-10-11 Last modified: 2024-01-17 Method: X-RAY DIFFRACTION (2 Å) Cite: Rational Design of an Anticalin-Type Sugar-Binding Protein Using a Genetically Encoded Boronate Side Chain. ACS Synth Biol, 6, 2017
7OPB	IL7R in complex with an antagonist Descriptor: 1,2-ETHANEDIOL, DI(HYDROXYETHYL)ETHER, IL7R binder, ... Authors: Markovic, I, Verschueren, K.H.G, Verstraete, K, Savvides, S.N. Deposit date: 2021-05-31 Release date: 2022-05-11 Last modified: 2024-01-31 Method: X-RAY DIFFRACTION (2.144 Å) Cite: Design of protein-binding proteins from the target structure alone. Nature, 605, 2022
5WRC	Crystal structure of proteinase K from Engyodontium album Descriptor: NITRATE ION, PRASEODYMIUM ION, Proteinase K Authors: Sugahara, M, Nakane, T, Suzuki, M, Masuda, T, Inoue, S, Numata, K. Deposit date: 2016-12-01 Release date: 2017-11-29 Last modified: 2023-09-06 Method: X-RAY DIFFRACTION (1.5 Å) Cite: Hydroxyethyl cellulose matrix applied to serial crystallography Sci Rep, 7, 2017
5Z1O	Crystal structure of an OspA mutant Descriptor: Outer Surface Protein A Authors: Takada, S, Makabe, K. Deposit date: 2017-12-27 Release date: 2019-01-02 Last modified: 2023-11-22 Method: X-RAY DIFFRACTION (2 Å) Cite: Crystal structure of an OspA mutant. To Be Published
7OVO	Heterodimeric murine tRNA-guanine transglycosylase in complex with queuine Descriptor: 2-amino-5-({[(1S,4S,5R)-4,5-dihydroxycyclopent-2-en-1-yl]amino}methyl)-3,7-dihydro-4H-pyrrolo[2,3-d]pyrimidin-4-one, DIMETHYL SULFOXIDE, Queuine tRNA-ribosyltransferase accessory subunit 2, ... Authors: Sebastiani, M, Heine, A, Reuter, K. Deposit date: 2021-06-15 Release date: 2022-06-22 Last modified: 2024-02-07 Method: X-RAY DIFFRACTION (2.1 Å) Cite: Structural and Biochemical Investigation of the Heterodimeric Murine tRNA-Guanine Transglycosylase. Acs Chem.Biol., 17, 2022

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