PDB: 224004 resultsInfo pagesStatus searchChemie searchBIRD

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8TNJ	Cryo-EM structure of HLA-B*73:01 bound to a 9mer peptide and two Fabs Descriptor: 9mer peptide,Beta-2-microglobulin,MHC class I antigen chimera, B.1 Fab heavy chain, B.1 Fab light chain, ... Authors: Ross, P, Adams, E.J, Lodwick, J, Zhao, M, Slezak, T, Kossiakoff, A. Deposit date: 2023-08-02 Release date: 2024-08-14 Method: ELECTRON MICROSCOPY (3.1 Å) Cite: Cryo-EM structure of HLA-B*73:01 bound to a 9mer peptide and two Fabs To Be Published
8TNI	Cryo-EM structure of HIV-1 Env BG505 DS-SOSIP in complex with broadly neutralizing bi-specific antibody CAP256L-R27 targeting the CD4-binding site and the V2-apex Descriptor: 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, HIV-1 BG505 DS-SOSIP gp120, ... Authors: Zhou, T, Morano, N.C, Roark, R.S, Kwong, P.D, Xu, J. Deposit date: 2023-08-01 Release date: 2024-05-08 Method: ELECTRON MICROSCOPY (3.61 Å) Cite: Cryo-EM structure of HIV-1 Env BG505 DS-SOSIP in complex with broadly neutralizing bi-specific antibody CAP256L-R27 targeting the CD4-binding site and the V2-apex To Be Published
8TNH	Cryo-EM structure of HIV-1 Env BG505 DS-SOSIP in complex with broadly neutralizing llama nanobody G36 targeting the CD4-binding site Descriptor: 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, CD4-binding site nanobody G36, ... Authors: Zhou, T, Kwong, P.D, Xu, J. Deposit date: 2023-08-01 Release date: 2024-05-08 Method: ELECTRON MICROSCOPY (3.32 Å) Cite: Cryo-EM structure of HIV-1 Env BG505 DS-SOSIP in complex with broadly neutralizing llama nanobody G36 targeting the CD4-binding site To Be Published
8TNG	Cryo-EM structure of HIV-1 Env BG505 DS-SOSIP in complex with broadly neutralizing llama nanobody R27 targeting the CD4-binding site Descriptor: 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, CD4-binding site targeting nanobody R27, ... Authors: Zhou, T, Kwong, P.D, Xu, J. Deposit date: 2023-08-01 Release date: 2024-05-08 Method: ELECTRON MICROSCOPY (3.58 Å) Cite: Cryo-EM structure of HIV-1 Env BG505 DS-SOSIP in complex with broadly neutralizing llama nanobody R27 targeting the CD4-binding site To Be Published
8TNF	Crystal structure of sulfohexulose-1-phosphate aldolase from Paracoccus onubensis strain Merri Descriptor: DUF2090 domain-containing protein Authors: Lee, M. Deposit date: 2023-08-01 Release date: 2024-08-07 Method: X-RAY DIFFRACTION (2.5 Å) Cite: A patchwork pathway for catabolism degradation of the sulfosugar sulfofucose To Be Published
8TNE	Crystal structure of bacterial pectin methylesterase Pme8A from rumen Butyrivibrio Descriptor: 1,2-ETHANEDIOL, Pectinesterase Authors: Carbone, V, Reilly, K, Sang, C, Schofield, L, Ronimus, R, Kelly, W.J, Attwood, G.T, Palevich, N. Deposit date: 2023-08-01 Release date: 2023-08-16 Last modified: 2023-10-11 Method: X-RAY DIFFRACTION (2.3 Å) Cite: Crystal Structures of Bacterial Pectin Methylesterases Pme8A and PmeC2 from Rumen Butyrivibrio . Int J Mol Sci, 24, 2023
8TND	De novo designed protein binds poly ADP ribose polymerase inhibitors (PARPi) - holo veliparib Descriptor: (2R)-2-(7-carbamoyl-1H-benzimidazol-2-yl)-2-methylpyrrolidinium, De novo designed protein, SULFATE ION Authors: Lu, L, DeGrado, W.F. Deposit date: 2023-08-01 Release date: 2024-04-24 Method: X-RAY DIFFRACTION (1.29 Å) Cite: De novo design of drug-binding proteins with predictable binding energy and specificity. Science, 384, 2024
8TNC	De novo designed protein binds poly ADP ribose polymerase inhibitors (PARPi) - holo niraparib Descriptor: 2-{4-[(3S)-piperidin-3-yl]phenyl}-2H-indazole-7-carboxamide, De novo designed protein Authors: Lu, L, DeGrado, W.F. Deposit date: 2023-08-01 Release date: 2024-04-24 Method: X-RAY DIFFRACTION (1.4 Å) Cite: De novo design of drug-binding proteins with predictable binding energy and specificity. Science, 384, 2024
8TNB	De novo designed protein binds poly ADP ribose polymerase inhibitors (PARPi) - holo mefuparib Descriptor: 5-fluoro-2-{4-[(methylamino)methyl]phenyl}-1-benzofuran-7-carboxamide, De novo designed protein Authors: Lu, L, DeGrado, W.F. Deposit date: 2023-08-01 Release date: 2024-04-24 Method: X-RAY DIFFRACTION (1.4 Å) Cite: De novo design of drug-binding proteins with predictable binding energy and specificity. Science, 384, 2024
8TN9	Structural architecture of the acidic region of the B domain of coagulation factor V Descriptor: 2-acetamido-2-deoxy-beta-D-glucopyranose, Coagulation factor V Authors: Mohammed, B.M, Basore, K, Summers, B, Pelc, L.A, Di Cera, E. Deposit date: 2023-08-01 Release date: 2023-10-04 Last modified: 2024-03-13 Method: ELECTRON MICROSCOPY (3.05 Å) Cite: Structural architecture of the acidic region of the B domain of coagulation factor V. J.Thromb.Haemost., 22, 2024
8TN8	Crystal structure of the murine astrovirus capsid spike at 1.75 A Descriptor: Capsid polyprotein VP90, POTASSIUM ION Authors: Lanning, S, DuBois, R.M. Deposit date: 2023-08-01 Release date: 2023-11-15 Method: X-RAY DIFFRACTION (1.75 Å) Cite: Structure and immunogenicity of the murine astrovirus capsid spike. J.Gen.Virol., 104, 2023
8TN6	De novo designed protein binds poly ADP ribose polymerase inhibitors (PARPi) - holo rucaparib Descriptor: De novo designed protein, Rucaparib Authors: Lu, L, DeGrado, W.F. Deposit date: 2023-08-01 Release date: 2024-04-24 Method: X-RAY DIFFRACTION (1.36 Å) Cite: De novo design of drug-binding proteins with predictable binding energy and specificity. Science, 384, 2024
8TN3	Structure of S. hygroscopicus aminotransferase MppQ complexed with pyridoxamine 5'-phosphate (PMP) Descriptor: 4'-DEOXY-4'-AMINOPYRIDOXAL-5'-PHOSPHATE, PLP-dependent aminotransferase MppQ Authors: Silvaggi, N.R, Vuksanovic, N. Deposit date: 2023-08-01 Release date: 2023-11-22 Method: X-RAY DIFFRACTION (1.63 Å) Cite: Structural and Biochemical Characterization of MppQ, an L-Enduracididine Biosynthetic Enzyme from Streptomyces hygroscopicus. Biochemistry, 62, 2023
8TN2	Structure of S. hygroscopicus aminotransferase MppQ complexed with pyridoxal-5'-phosphate (PLP) Descriptor: PLP-dependent aminotransferase MppQ Authors: Silvaggi, N.R, Vuksanovic, N. Deposit date: 2023-08-01 Release date: 2023-11-22 Method: X-RAY DIFFRACTION (1.75 Å) Cite: Structural and Biochemical Characterization of MppQ, an L-Enduracididine Biosynthetic Enzyme from Streptomyces hygroscopicus. Biochemistry, 62, 2023
8TN1	De novo designed protein binds poly ADP ribose polymerase inhibitors (PARPi) - apo Descriptor: De novo designed 4 helix bundles, SULFATE ION Authors: Lu, L, DeGrado, W.F. Deposit date: 2023-08-01 Release date: 2024-04-24 Method: X-RAY DIFFRACTION (1.61 Å) Cite: De novo design of drug-binding proteins with predictable binding energy and specificity. Science, 384, 2024
8TN0	Crystal structure of KPC-44 carbapenemase w/o cryoprotectant Descriptor: SULFATE ION, beta-lactamase Authors: Sun, Z, Palzkill, T, Hu, L, Lin, H, Sankaran, B, Wang, J, Prasad, B. Deposit date: 2023-07-31 Release date: 2023-12-06 Last modified: 2023-12-27 Method: X-RAY DIFFRACTION (1.31 Å) Cite: Klebsiella pneumoniae carbapenemase variant 44 acquires ceftazidime-avibactam resistance by altering the conformation of active-site loops. J.Biol.Chem., 300, 2023
8TMZ	Crystal structure of MERS-CoV spike stem helix peptide in complex with neutralizing antibody CHM-27 Descriptor: 1,2-ETHANEDIOL, Neutralizing antibody CHM-27 Heavy Chain, Neutralizing antibody CHM-27 Light Chain, ... Authors: Yuan, M, Wilson, I.A. Deposit date: 2023-07-31 Release date: 2024-07-31 Method: X-RAY DIFFRACTION (1.8 Å) Cite: Broad Neutralizing Antibodies Against Coronaviruses. Not published
8TMY	Crystal structure of SARS-CoV-2 spike stem helix peptide in complex with neutralizing antibody CHM-16 Descriptor: CITRATE ANION, Neutralizing antibody CHM-16 Heavy Chain, Neutralizing antibody CHM-16 Light Chain, ... Authors: Feng, Z, Wilson, I.A. Deposit date: 2023-07-31 Release date: 2024-07-31 Method: X-RAY DIFFRACTION (3.07 Å) Cite: Broad Neutralizing Antibodies Against Coronaviruses. Not published
8TMW	HTLV-1 capsid protein N-terminal domain triclinic crystal form with sulphate ion Descriptor: SULFATE ION, capsid protein p24 Authors: Yu, R.J, Li, N, Jacques, D.A. Deposit date: 2023-07-31 Release date: 2024-08-07 Method: X-RAY DIFFRACTION (1.71 Å) Cite: HTLV-1 capsid protein N-terminal domain triclinic crystal form with sulphate ion To Be Published
8TMV	HTLV-1 capsid protein N-terminal domain triclinic crystal form with phosphate ion Descriptor: PHOSPHATE ION, capsid protein p24 Authors: Yu, R.J, Li, N, Jacques, D.A. Deposit date: 2023-07-31 Release date: 2024-08-07 Method: X-RAY DIFFRACTION (1.73 Å) Cite: HTLV-1 capsid protein N-terminal domain triclinic crystal form with phosphate ion To Be Published
8TMT	Crystal structure of KPC-44 carbapenemase in complex with vaborbactam Descriptor: 1,2-ETHANEDIOL, GLYCEROL, LITHIUM ION, ... Authors: Sun, Z, Palzkill, T, Hu, L, Neetu, N, Lin, H, Sankaran, B, Wang, J, Prasad, B. Deposit date: 2023-07-30 Release date: 2023-12-06 Last modified: 2023-12-27 Method: X-RAY DIFFRACTION (1.7 Å) Cite: Klebsiella pneumoniae carbapenemase variant 44 acquires ceftazidime-avibactam resistance by altering the conformation of active-site loops. J.Biol.Chem., 300, 2023
8TMS	Crystal structure of bacterial pectin methylesterase PmeC2 from rumen Butyrivibrio Descriptor: 1,2-ETHANEDIOL, CHLORIDE ION, Pectinesterase Authors: Carbone, V, Reilly, K, Sang, C, Schofield, L, Ronimus, R, Kelly, W.J, Attwood, G.T, Palevich, N. Deposit date: 2023-07-30 Release date: 2023-08-16 Last modified: 2023-10-11 Method: X-RAY DIFFRACTION (2.3 Å) Cite: Crystal Structures of Bacterial Pectin Methylesterases Pme8A and PmeC2 from Rumen Butyrivibrio . Int J Mol Sci, 24, 2023
8TMR	Crystal structure of KPC-44 carbapenemase complexed with avibactam Descriptor: (2S,5R)-1-formyl-5-[(sulfooxy)amino]piperidine-2-carboxamide, 1,2-ETHANEDIOL, PHOSPHATE ION, ... Authors: Sun, Z, Palzkill, T, Hu, L, Lin, H, Sankaran, B, Wang, J, Prasad, B. Deposit date: 2023-07-30 Release date: 2023-12-06 Last modified: 2023-12-27 Method: X-RAY DIFFRACTION (1.37 Å) Cite: Klebsiella pneumoniae carbapenemase variant 44 acquires ceftazidime-avibactam resistance by altering the conformation of active-site loops. J.Biol.Chem., 300, 2023
8TMA	Antibody N3-1 bound to RBD in the up conformation Descriptor: N3-1 Fab heavy chain, N3-1 Fab light chain, Spike glycoprotein Authors: Hsieh, C.-L, McLellan, J.S. Deposit date: 2023-07-29 Release date: 2024-01-17 Method: ELECTRON MICROSCOPY (3.2 Å) Cite: SARS-COV-2 Omicron variants conformationally escape a rare quaternary antibody binding mode. Commun Biol, 6, 2023
8TM7	Human NAMPT in complex with substrate NAM and small molecule activator NP-A3 Descriptor: CHLORIDE ION, GLYCEROL, N-{2-[(4R)-2,2-dimethyl-4-(propan-2-yl)oxan-4-yl]ethyl}-N-[(4-methoxyphenyl)methyl]furan-2-carboxamide, ... Authors: Ratia, K.M, Thatcher, G.R. Deposit date: 2023-07-28 Release date: 2024-06-12 Method: X-RAY DIFFRACTION (1.79 Å) Cite: Nicotinamide Phosphoribosyltransferase Positive Allosteric Modulators Attenuate Neuronal Oxidative Stress. Acs Med.Chem.Lett., 15, 2024

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