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7EG7
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BU of 7eg7 by Molmil
TFIID-based core PIC on SCP promoter
Descriptor: DNA (79-MER), DNA-directed RNA polymerase II subunit E, DNA-directed RNA polymerase II subunit F, ...
Authors:Chen, X, Qi, Y, Hou, H, Wang, X, Wu, Z, Li, J, Xu, Y.
Deposit date:2021-03-24
Release date:2021-05-05
Last modified:2021-05-19
Method:ELECTRON MICROSCOPY (6.2 Å)
Cite:Structural insights into preinitiation complex assembly on core promoters.
Science, 372, 2021
2M4V
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BU of 2m4v by Molmil
Mycobacterium tuberculosis RNA polymerase binding protein A (RbpA) and its interactions with sigma factors
Descriptor: Putative uncharacterized protein
Authors:Bortoluzzi, A, Muskett, F.W, Waters, L.C, Addis, P.W, Rieck, B, Munder, T, Schleier, S, Forti, F, Ghisotti, D, Carr, M.D, O'Hare, H.M.
Deposit date:2013-02-11
Release date:2013-04-17
Last modified:2024-05-15
Method:SOLUTION NMR
Cite:Mycobacterium tuberculosis RNA polymerase-binding protein A (RbpA) and its interactions with sigma factors.
J.Biol.Chem., 288, 2013
2JT9
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BU of 2jt9 by Molmil
NMR structure of immunosuppressory peptide containing cyclolinopeptide X and antennapedia(43-58) sequences
Descriptor: 5-mer immunosuppressory peptide from cyclolinopeptide X, 6-AMINOHEXANOIC ACID, GAMMA-AMINO-BUTANOIC ACID, ...
Authors:Jaremko, L, Jaremko, M, Zhukov, I, Cebrat, M.
Deposit date:2007-07-21
Release date:2008-07-29
Last modified:2023-11-15
Method:SOLUTION NMR
Cite:NMR structure of immunosuppressory peptide containing cyclolinopeptide X and antennapedia(43-58) sequences
To be Published
2PV9
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BU of 2pv9 by Molmil
Crystal structure of murine thrombin in complex with the extracellular fragment of murine PAR4
Descriptor: 2-acetamido-2-deoxy-beta-D-glucopyranose, Proteinase-activated receptor 4, Thrombin heavy chain, ...
Authors:Bah, A, Chen, Z, Bush-Pelc, L.A, Mathews, F.S, Di Cera, E.
Deposit date:2007-05-09
Release date:2007-07-10
Last modified:2023-08-30
Method:X-RAY DIFFRACTION (3.5 Å)
Cite:Crystal structures of murine thrombin in complex with the extracellular fragments of murine protease-activated receptors PAR3 and PAR4.
Proc.Natl.Acad.Sci.Usa, 104, 2007
2JU0
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BU of 2ju0 by Molmil
Structure of Yeast Frequenin bound to PdtIns 4-kinase
Descriptor: CALCIUM ION, Calcium-binding protein NCS-1, Phosphatidylinositol 4-kinase PIK1
Authors:Ames, J.
Deposit date:2007-08-11
Release date:2007-08-28
Last modified:2024-05-29
Method:SOLUTION NMR
Cite:Structural insights into activation of phosphatidylinositol 4-kinase (Pik1) by yeast frequenin (Frq1).
J.Biol.Chem., 282, 2007
7S10
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BU of 7s10 by Molmil
Crystal Structure of ascorbate peroxidase triple mutant: S160M, L203M, Q204M
Descriptor: L-ascorbate peroxidase, POTASSIUM ION, PROTOPORPHYRIN IX CONTAINING FE, ...
Authors:Poulos, T.L, Kim, J, Murarka, V.
Deposit date:2021-08-31
Release date:2022-09-07
Last modified:2023-10-18
Method:X-RAY DIFFRACTION (1.40000689 Å)
Cite:Computational analysis of the tryptophan cation radical energetics in peroxidase Compound I.
J.Biol.Inorg.Chem., 27, 2022
2RMU
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BU of 2rmu by Molmil
THREE-DIMENSIONAL STRUCTURES OF DRUG-RESISTANT MUTANTS OF HUMAN RHINOVIRUS 14
Descriptor: HUMAN RHINOVIRUS 14 COAT PROTEIN (SUBUNIT VP1), HUMAN RHINOVIRUS 14 COAT PROTEIN (SUBUNIT VP2), HUMAN RHINOVIRUS 14 COAT PROTEIN (SUBUNIT VP3), ...
Authors:Badger, J, Krishnaswamy, S, Kremer, M.J, Oliveira, M.A, Rossmann, M.G, Heinz, B.A, Rueckert, R.R, Dutko, F.J, Mckinlay, M.A.
Deposit date:1988-10-03
Release date:1990-01-15
Last modified:2024-05-22
Method:X-RAY DIFFRACTION (3 Å)
Cite:Three-dimensional structures of drug-resistant mutants of human rhinovirus 14.
J.Mol.Biol., 207, 1989
2MZZ
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BU of 2mzz by Molmil
NMR structure of APOBEC3G NTD variant, sNTD
Descriptor: Apolipoprotein B mRNA-editing enzyme, catalytic polypeptide-like 3G variant, ZINC ION
Authors:Kouno, T, Luengas, E.M, Shigematu, M, Shandilya, S.M.D, Zhang, J, Chen, L, Hara, M, Schiffer, C.A, Harris, R.S, Matsuo, H.
Deposit date:2015-02-28
Release date:2015-05-13
Last modified:2024-05-15
Method:SOLUTION NMR
Cite:Structure of the Vif-binding domain of the antiviral enzyme APOBEC3G.
Nat.Struct.Mol.Biol., 22, 2015
6P5K
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BU of 6p5k by Molmil
Structure of a mammalian 80S ribosome in complex with the Israeli Acute Paralysis Virus IRES (Class 3)
Descriptor: 18S rRNA, 28S rRNA, 5.8S rRNA, ...
Authors:Acosta-Reyes, F.J, Neupane, R, Frank, J, Fernandez, I.S.
Deposit date:2019-05-30
Release date:2019-09-18
Last modified:2020-01-08
Method:ELECTRON MICROSCOPY (3.1 Å)
Cite:The Israeli acute paralysis virus IRES captures host ribosomes by mimicking a ribosomal state with hybrid tRNAs.
Embo J., 38, 2019
7NSQ
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BU of 7nsq by Molmil
Structure of ErmDL-Telithromycin-stalled 70S E. coli ribosomal complex with A and P-tRNA
Descriptor: 16S rRNA, 23S rRNA, 30S ribosomal protein S10, ...
Authors:Beckert, B, Wilson, D.N.
Deposit date:2021-03-08
Release date:2021-07-14
Last modified:2021-08-11
Method:ELECTRON MICROSCOPY (3.1 Å)
Cite:Structural and mechanistic basis for translation inhibition by macrolide and ketolide antibiotics.
Nat Commun, 12, 2021
7NSO
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BU of 7nso by Molmil
Structure of ErmDL-Erythromycin-stalled 70S E. coli ribosomal complex with P-tRNA
Descriptor: 16S rRNA (1540-MER), 23S rRNA (2903-MER), 30S ribosomal protein S10, ...
Authors:Beckert, B, Wilson, D.N.
Deposit date:2021-03-08
Release date:2021-07-14
Last modified:2021-08-11
Method:ELECTRON MICROSCOPY (2.9 Å)
Cite:Structural and mechanistic basis for translation inhibition by macrolide and ketolide antibiotics.
Nat Commun, 12, 2021
6PBG
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BU of 6pbg by Molmil
Crystal structure of WD-repeat domain of human coatomer subunit Alpha (COPA)
Descriptor: Coatomer subunit alpha, L(+)-TARTARIC ACID, UNKNOWN ATOM OR ION
Authors:Halabelian, L, Zeng, H, Dong, A, Loppnau, P, Seitova, A, Hutchinson, A, Bountra, C, Edwards, A.M, Arrowsmith, C.H, Structural Genomics Consortium (SGC)
Deposit date:2019-06-13
Release date:2019-06-26
Last modified:2023-10-11
Method:X-RAY DIFFRACTION (1.72 Å)
Cite:Crystal structure of W repeat domain of human coatomer subunit Alpha (COPA)
to be published
6PG5
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BU of 6pg5 by Molmil
WDR5delta32 bound to benzyl (4-(5-(hydroxymethyl)-1H-imidazol-2-yl)butyl)carbamate
Descriptor: SULFATE ION, WD repeat-containing protein 5, benzyl {4-[5-(hydroxymethyl)-1H-imidazol-2-yl]butyl}carbamate
Authors:Dennis, M.L, Peat, T.S.
Deposit date:2019-06-24
Release date:2019-12-11
Last modified:2023-10-11
Method:X-RAY DIFFRACTION (1.99 Å)
Cite:Fragment screening for a protein-protein interaction inhibitor to WDR5.
Struct Dyn., 6, 2019
6PGB
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BU of 6pgb by Molmil
WDR5delta32 bound to N-(4-(5-(hydroxymethyl)-1H-imidazol-2-yl)butyl)-2-phenylacetamide
Descriptor: N-{4-[5-(hydroxymethyl)-1H-imidazol-2-yl]butyl}-2-phenylacetamide, SULFATE ION, WD repeat-containing protein 5
Authors:Dennis, M.L, Peat, T.S.
Deposit date:2019-06-24
Release date:2019-12-11
Last modified:2023-10-11
Method:X-RAY DIFFRACTION (1.73 Å)
Cite:Fragment screening for a protein-protein interaction inhibitor to WDR5.
Struct Dyn., 6, 2019
8Q6M
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BU of 8q6m by Molmil
Human SOD1 low dose data collecton
Descriptor: ACETATE ION, COPPER (II) ION, SULFATE ION, ...
Authors:Antonyuk, S.V, Hossain, A, Agar, J.N, Hasnain, S.S.
Deposit date:2023-08-14
Release date:2023-12-13
Last modified:2024-02-07
Method:X-RAY DIFFRACTION (1.77 Å)
Cite:Evaluating protein cross-linking as a therapeutic strategy to stabilize SOD1 variants in a mouse model of familial ALS.
Plos Biol., 22, 2024
6PG3
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BU of 6pg3 by Molmil
WDR5delta23 bound to (2-butyl-1H-imidazol-4-yl)methanol
Descriptor: (2-butyl-1H-imidazol-4-yl)methanol, WD repeat-containing protein 5
Authors:Dennis, M.L, Peat, T.S.
Deposit date:2019-06-24
Release date:2019-12-11
Last modified:2023-10-11
Method:X-RAY DIFFRACTION (2.04 Å)
Cite:Fragment screening for a protein-protein interaction inhibitor to WDR5.
Struct Dyn., 6, 2019
7NSU
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BU of 7nsu by Molmil
ColicinE9 intact translocation complex
Descriptor: Colicin-E9, Outer membrane protein F, Tol-Pal system protein TolB, ...
Authors:Webby, M.N, Kleanthous, C, Lukoyanova, N, Housden, N.G.
Deposit date:2021-03-08
Release date:2021-08-11
Last modified:2021-11-17
Method:ELECTRON MICROSCOPY (4.7 Å)
Cite:Porin threading drives receptor disengagement and establishes active colicin transport through Escherichia coli OmpF.
Embo J., 40, 2021
7NYH
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BU of 7nyh by Molmil
Respiratory complex I from Escherichia coli - focused refinement of membrane arm
Descriptor: NADH-quinone oxidoreductase subunit A, NADH-quinone oxidoreductase subunit H, NADH-quinone oxidoreductase subunit J, ...
Authors:Kolata, P, Efremov, R.G.
Deposit date:2021-03-22
Release date:2021-08-18
Last modified:2024-07-10
Method:ELECTRON MICROSCOPY (3.6 Å)
Cite:Structure of Escherichia coli respiratory complex I reconstituted into lipid nanodiscs reveals an uncoupled conformation.
Elife, 10, 2021
7NSP
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BU of 7nsp by Molmil
Structure of ErmDL-Erythromycin-stalled 70S E. coli ribosomal complex with A and P-tRNA
Descriptor: 16S rRNA, 23S rRNA, 30S ribosomal protein S10, ...
Authors:Beckert, B, Wilson, D.N.
Deposit date:2021-03-08
Release date:2021-08-11
Method:ELECTRON MICROSCOPY (3.5 Å)
Cite:Structural and mechanistic basis for translation inhibition by macrolide and ketolide antibiotics.
Nat Commun, 12, 2021
7NXD
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BU of 7nxd by Molmil
Cryo-EM structure of human integrin alpha5beta1 in the half-bent conformation
Descriptor: 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-2)-alpha-D-mannopyranose-(1-6)-[alpha-D-mannopyranose-(1-3)]beta-D-mannopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, ...
Authors:Schumacher, S, Dedden, D, Vazquez Nunez, R, Matoba, K, Takagi, J, Biertumpfel, C, Mizuno, N.
Deposit date:2021-03-18
Release date:2021-08-25
Method:ELECTRON MICROSCOPY (4.6 Å)
Cite:Structural insights into integrin alpha 5 beta 1 opening by fibronectin ligand.
Sci Adv, 7, 2021
7O82
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BU of 7o82 by Molmil
The L-arginine/agmatine antiporter from E. coli at 1.7 A resolution
Descriptor: 2-AMINO-2-HYDROXYMETHYL-PROPANE-1,3-DIOL, Arginine/agmatine antiporter, DECANE, ...
Authors:Jeckelmann, J.M, Ilgue, H, Kalbermatter, D, Fotiadis, D.
Deposit date:2021-04-14
Release date:2021-09-08
Last modified:2024-01-31
Method:X-RAY DIFFRACTION (1.69 Å)
Cite:High-resolution structure of the amino acid transporter AdiC reveals insights into the role of water molecules and networks in oligomerization and substrate binding.
Bmc Biol., 19, 2021
7O1V
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BU of 7o1v by Molmil
Structure of a Minimal Photosystem I
Descriptor: 1,2-DI-O-ACYL-3-O-[6-DEOXY-6-SULFO-ALPHA-D-GLUCOPYRANOSYL]-SN-GLYCEROL, 1,2-DIPALMITOYL-PHOSPHATIDYL-GLYCEROLE, 1,2-DISTEAROYL-MONOGALACTOSYL-DIGLYCERIDE, ...
Authors:Nelson, N, Caspy, I, Lambrev, P.
Deposit date:2021-03-30
Release date:2021-09-01
Last modified:2024-07-10
Method:ELECTRON MICROSCOPY (4.31 Å)
Cite:Two-Dimensional Electronic Spectroscopy of a Minimal Photosystem I Complex Reveals the Rate of Primary Charge Separation.
J.Am.Chem.Soc., 143, 2021
6PG8
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BU of 6pg8 by Molmil
WDR5delta23 bound to (2-(3-phenylpropyl)-1H-imidazol-4-yl)methanol
Descriptor: CHLORIDE ION, SULFATE ION, WD repeat-containing protein 5, ...
Authors:Dennis, M.L, Peat, T.S.
Deposit date:2019-06-24
Release date:2019-12-11
Last modified:2023-10-11
Method:X-RAY DIFFRACTION (1.67 Å)
Cite:Fragment screening for a protein-protein interaction inhibitor to WDR5.
Struct Dyn., 6, 2019
7NUS
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BU of 7nus by Molmil
X-RAY STRUCTURE OF HDM2/CMR19 AT 1.45A: Discovery, X-ray structure and CPP-conjugation enabled uptake of p53/MDM2 macrocyclic peptide inhibitors
Descriptor: CHLORIDE ION, E3 ubiquitin-protein ligase Mdm2, SULFATE ION, ...
Authors:Kallen, J.
Deposit date:2021-03-13
Release date:2021-09-22
Last modified:2024-01-31
Method:X-RAY DIFFRACTION (1.45 Å)
Cite:Discovery, X-ray structure and CPP-conjugation enabled uptake of p53/MDM2 macrocyclic peptide inhibitors.
Rsc Chem Biol, 2, 2021
6PBR
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BU of 6pbr by Molmil
Catalytic domain of E.coli dihydrolipoamide succinyltransferase in I4 space group
Descriptor: Dihydrolipoyllysine-residue succinyltransferase component of 2-oxoglutarate dehydrogenase complex, SODIUM ION
Authors:Andi, B, Soares, A.S, Shi, W, Fuchs, M.R, McSweeney, S, Liu, Q.
Deposit date:2019-06-14
Release date:2019-06-26
Last modified:2023-10-11
Method:X-RAY DIFFRACTION (3 Å)
Cite:Structure of the dihydrolipoamide succinyltransferase catalytic domain from Escherichia coli in a novel crystal form: a tale of a common protein crystallization contaminant.
Acta Crystallogr.,Sect.F, 75, 2019

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數據於2024-07-24公開中

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