2APQ
 
 | | Crystal Structure of an Active Site Mutant of Bovine Pancreatic Ribonuclease A (H119A-RNase A) with a 10-Glutamine expansion in the C-terminal hinge-loop. | | Descriptor: | PHOSPHATE ION, Ribonuclease | | Authors: | Sambashivan, S, Liu, Y, Sawaya, M.R, Gingery, M, Eisenberg, D. | | Deposit date: | 2005-08-16 | | Release date: | 2005-09-13 | | Last modified: | 2024-10-16 | | Method: | X-RAY DIFFRACTION (1.8 Å) | | Cite: | Amyloid-like fibrils of ribonuclease A with three-dimensional domain-swapped and native-like structure.
Nature, 437, 2005
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1YMR
 | | The study of reductive unfolding pathways of RNase A (Y92A mutant) | | Descriptor: | Ribonuclease pancreatic | | Authors: | Xu, G, Narayan, M, Kurinov, I, Ripoll, D.R, Welker, E, Khalili, M, Ealick, S.E, Scheraga, H.A. | | Deposit date: | 2005-01-21 | | Release date: | 2006-01-31 | | Last modified: | 2021-10-20 | | Method: | X-RAY DIFFRACTION (1.5 Å) | | Cite: | A localized specific interaction alters the unfolding pathways of structural homologues.
J.Am.Chem.Soc., 128, 2006
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1Z5F
 | | Solution Structure of the Cytotoxic RC-RNase 3 with a Pyroglutamate Residue at the N-terminus | | Descriptor: | RC-RNase 3 | | Authors: | Lou, Y.C, Huang, Y.C, Pan, Y.R, Chen, C, Liao, Y.D. | | Deposit date: | 2005-03-18 | | Release date: | 2006-02-28 | | Last modified: | 2019-12-25 | | Method: | SOLUTION NMR | | Cite: | Roles of N-terminal pyroglutamate in maintaining structural integrity and pKa values of catalytic histidine residues in bullfrog ribonuclease 3
J.Mol.Biol., 355, 2006
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1Z3L
 | | X-Ray Crystal Structure of a Mutant Ribonuclease S (F8Anb) | | Descriptor: | Ribonuclease pancreatic, S-Peptide, S-Protein, ... | | Authors: | Das, M, Vasudeva Rao, B, Ghosh, S, Varadarajan, R. | | Deposit date: | 2005-03-14 | | Release date: | 2005-03-29 | | Last modified: | 2023-11-15 | | Method: | X-RAY DIFFRACTION (1.8 Å) | | Cite: | Attempts to delineate the relative contributions of changes in hydrophobicity and packing to changes in stability of ribonuclease S mutants.
Biochemistry, 44, 2005
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1YV4
 | | X-ray structure of M23L onconase at 100K | | Descriptor: | P-30 protein, SULFATE ION | | Authors: | Merlino, A, Mazzarella, L, Carannante, A, Di Fiore, A, Di Donato, A, Notomista, E, Sica, F. | | Deposit date: | 2005-02-15 | | Release date: | 2005-03-01 | | Last modified: | 2023-10-25 | | Method: | X-RAY DIFFRACTION (1.51 Å) | | Cite: | The Importance of Dynamic Effects on the Enzyme Activity: X-RAY STRUCTURE AND MOLECULAR DYNAMICS OF ONCONASE MUTANTS
J.Biol.Chem., 280, 2005
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1Z6S
 | | Ribonuclease A- AMP complex | | Descriptor: | ADENOSINE MONOPHOSPHATE, Ribonuclease pancreatic | | Authors: | Hatzopoulos, G.N, Leonidas, D.D, Kardakaris, R, Kobe, J, Oikonomakos, N.G. | | Deposit date: | 2005-03-23 | | Release date: | 2005-08-16 | | Last modified: | 2011-07-13 | | Method: | X-RAY DIFFRACTION (1.5 Å) | | Cite: | The binding of IMP to Ribonuclease A
Febs J., 272, 2005
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2C01
 | | Crystal Structures of Eosinophil-derived Neurotoxin in Complex with the Inhibitors 5'-ATP, Ap3A, Ap4A and Ap5A | | Descriptor: | ACETIC ACID, ADENOSINE-5'-TRIPHOSPHATE, NONSECRETORY RIBONUCLEASE | | Authors: | Baker, M.D, Holloway, D.E, Swaminathan, G.J, Acharya, K.R. | | Deposit date: | 2005-08-24 | | Release date: | 2006-01-18 | | Last modified: | 2024-10-16 | | Method: | X-RAY DIFFRACTION (1.24 Å) | | Cite: | Crystal Structures of Eosinophil-Derived Neurotoxin (Edn) in Complex with the Inhibitors 5'- ATP, Ap(3)A, Ap(4)A, and Ap(5)A.
Biochemistry, 45, 2006
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2BLZ
 | | RNAse after a high dose X-ray "burn" | | Descriptor: | CHLORIDE ION, RIBONUCLEASE PANCREATIC | | Authors: | Nanao, M.H, Ravelli, R.B. | | Deposit date: | 2005-03-08 | | Release date: | 2005-09-07 | | Last modified: | 2011-07-13 | | Method: | X-RAY DIFFRACTION (1.4 Å) | | Cite: | Improving Radiation-Damage Substructures for Rip.
Acta Crystallogr.,Sect.D, 61, 2005
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2BWL
 | | Murine angiogenin, phosphate complex | | Descriptor: | ANGIOGENIN, PHOSPHATE ION | | Authors: | Holloway, D.E, Chavali, G.B, Hares, M.C, Subramanian, V, Acharya, K.R. | | Deposit date: | 2005-07-15 | | Release date: | 2005-11-30 | | Last modified: | 2023-12-13 | | Method: | X-RAY DIFFRACTION (1.62 Å) | | Cite: | Structure of Murine Angiogenin: Features of the Substrate- and Cell-Binding Regions and Prospects for Inhibitor-Binding Studies.
Acta Crystallogr.,Sect.D, 61, 2005
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2BZZ
 | | Crystal Structures of Eosinophil-derived Neurotoxin in Complex with the Inhibitors 5'-ATP, Ap3A, Ap4A and Ap5A | | Descriptor: | ACETIC ACID, BIS(ADENOSINE)-5'-PENTAPHOSPHATE, NONSECRETORY RIBONUCLEASE | | Authors: | Baker, M.D, Holloway, D.E, Swaminathan, G.J, Acharya, K.R. | | Deposit date: | 2005-08-24 | | Release date: | 2006-01-18 | | Last modified: | 2023-12-13 | | Method: | X-RAY DIFFRACTION (0.98 Å) | | Cite: | Crystal Structures of Eosinophil-Derived Neurotoxin (Edn) in Complex with the Inhibitors 5'- ATP, Ap(3)A, Ap(4)A, and Ap(5)A.
Biochemistry, 45, 2006
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1JVV
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1K58
 | | Crystal Structure of Human Angiogenin Variant D116H | | Descriptor: | Angiogenin | | Authors: | Leonidas, D.D, Shapiro, R, Subbarao, G.V, Russo, A, Acharya, K.R. | | Deposit date: | 2001-10-10 | | Release date: | 2002-03-20 | | Last modified: | 2023-08-16 | | Method: | X-RAY DIFFRACTION (2.7 Å) | | Cite: | Crystallographic studies on the role of the C-terminal segment of human angiogenin in defining enzymatic potency.
Biochemistry, 41, 2002
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1K59
 | | Crystal Structure of Human Angiogenin Variant Q117G | | Descriptor: | CITRIC ACID, angiogenin | | Authors: | Leonidas, D.D, Shapiro, R, Subbarao, G.V, Russo, A, Acharya, K.R. | | Deposit date: | 2001-10-10 | | Release date: | 2002-03-20 | | Last modified: | 2023-08-16 | | Method: | X-RAY DIFFRACTION (1.8 Å) | | Cite: | Crystallographic studies on the role of the C-terminal segment of human angiogenin in defining enzymatic potency.
Biochemistry, 41, 2002
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1KF8
 | | Atomic resolution structure of RNase A at pH 8.8 | | Descriptor: | pancreatic ribonuclease | | Authors: | Berisio, R, Sica, F, Lamzin, V.S, Wilson, K.S, Zagari, A, Mazzarella, L. | | Deposit date: | 2001-11-19 | | Release date: | 2001-12-19 | | Last modified: | 2023-08-16 | | Method: | X-RAY DIFFRACTION (1.15 Å) | | Cite: | Atomic resolution structures of ribonuclease A at six pH values.
Acta Crystallogr.,Sect.D, 58, 2002
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3F8G
 | | The X-ray structure of a dimeric variant of human pancreatic ribonuclease with high cytotoxic and antitumor activities | | Descriptor: | Ribonuclease pancreatic, SULFATE ION | | Authors: | Merlino, A, Avella, G, Mazzarella, L, Sica, F. | | Deposit date: | 2008-11-12 | | Release date: | 2009-02-10 | | Last modified: | 2023-09-06 | | Method: | X-RAY DIFFRACTION (2.6 Å) | | Cite: | Structural features for the mechanism of antitumor action of a dimeric human pancreatic ribonuclease variant.
Protein Sci., 18, 2009
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3FKZ
 | | X-ray structure of the non covalent swapped form of the S16G/T17N/A19P/A20S/K31C/S32C mutant of bovine pancreatic ribonuclease | | Descriptor: | Ribonuclease pancreatic | | Authors: | Merlino, A, Russo Krauss, I, Perillo, M, Mattia, C.A, Ercole, C, Picone, D, Vergara, A, Sica, F. | | Deposit date: | 2008-12-18 | | Release date: | 2009-03-24 | | Last modified: | 2023-11-01 | | Method: | X-RAY DIFFRACTION (1.99 Å) | | Cite: | Toward an antitumor form of bovine pancreatic ribonuclease: The crystal structure of three noncovalent dimeric mutants
Biopolymers, 91, 2009
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1KF3
 | | Atomic Resolution Structure of RNase A at pH 5.9 | | Descriptor: | SULFATE ION, pancreatic ribonuclease | | Authors: | Berisio, R, Sica, F, Lamzin, V.S, Wilson, K.S, Zagari, A, Mazzarella, L. | | Deposit date: | 2001-11-19 | | Release date: | 2001-12-19 | | Last modified: | 2023-08-16 | | Method: | X-RAY DIFFRACTION (1.05 Å) | | Cite: | Atomic resolution structures of ribonuclease A at six pH values.
Acta Crystallogr.,Sect.D, 58, 2002
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1KH8
 | | Structure of a cis-proline (P114) to glycine variant of Ribonuclease A | | Descriptor: | CESIUM ION, SULFATE ION, pancreatic ribonuclease A | | Authors: | Schultz, D.A, Friedman, A.M, White, M.A, Fox, R.O. | | Deposit date: | 2001-11-29 | | Release date: | 2003-06-17 | | Last modified: | 2024-04-03 | | Method: | X-RAY DIFFRACTION (2 Å) | | Cite: | The crystal structure of the cis-proline to glycine variant (P114G) of ribonuclease A.
Protein Sci., 14, 2005
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1LSQ
 | | RIBONUCLEASE A WITH ASN 67 REPLACED BY A BETA-ASPARTYL RESIDUE | | Descriptor: | RIBONUCLEASE A, SULFATE ION | | Authors: | Esposito, L, Sica, F, Vitagliano, L, Zagari, A, Mazzarella, L. | | Deposit date: | 1996-06-25 | | Release date: | 1997-01-11 | | Last modified: | 2024-10-16 | | Method: | X-RAY DIFFRACTION (1.9 Å) | | Cite: | Deamidation in proteins: the crystal structure of bovine pancreatic ribonuclease with an isoaspartyl residue at position 67.
J.Mol.Biol., 257, 1996
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3FD7
 | | Crystal structure of Onconase C87A/C104A-ONC | | Descriptor: | 1,2-ETHANEDIOL, GLYCEROL, Protein P-30, ... | | Authors: | Neumann, P, Schulenburg, C, Arnold, U, Ulbrich-Hofmann, R, Stubbs, M.T. | | Deposit date: | 2008-11-25 | | Release date: | 2009-12-08 | | Last modified: | 2023-11-01 | | Method: | X-RAY DIFFRACTION (1.531 Å) | | Cite: | Impact of the C-terminal disulfide bond on the folding and stability of onconase.
Chembiochem, 11, 2010
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1KF2
 | | Atomic Resolution Structure of RNase A at pH 5.2 | | Descriptor: | SULFATE ION, pancreatic ribonuclease | | Authors: | Berisio, R, Sica, F, Lamzin, V.S, Wilson, K.S, Zagari, A, Mazzarella, L. | | Deposit date: | 2001-11-19 | | Release date: | 2001-12-19 | | Last modified: | 2023-08-16 | | Method: | X-RAY DIFFRACTION (1.1 Å) | | Cite: | Atomic resolution structures of ribonuclease A at six pH values.
Acta Crystallogr.,Sect.D, 58, 2002
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1KVZ
 | | Solution Structure of Cytotoxic RC-RNase4 | | Descriptor: | RC-RNase4 | | Authors: | Hsu, C.-H, Liao, Y.-D, Chen, L.-W, Wu, S.-H, Chen, C. | | Deposit date: | 2002-01-28 | | Release date: | 2002-07-28 | | Last modified: | 2022-12-21 | | Method: | SOLUTION NMR | | Cite: | Solution Structure of the Cytotoxic RNase 4 from the Oocytes of Bullfrog Rana Catesbeiana
J.MOL.BIOL., 326, 2003
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1KF4
 | | Atomic Resolution Structure of RNase A at pH 6.3 | | Descriptor: | SULFATE ION, pancreatic ribonuclease | | Authors: | Berisio, R, Sica, F, Lamzin, V.S, Wilson, K.S, Zagari, A, Mazzarella, L. | | Deposit date: | 2001-11-19 | | Release date: | 2001-12-19 | | Last modified: | 2023-08-16 | | Method: | X-RAY DIFFRACTION (1.1 Å) | | Cite: | Atomic resolution structures of ribonuclease A at six pH values.
Acta Crystallogr.,Sect.D, 58, 2002
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1KF7
 | | Atomic Resolution Structure of RNase A at pH 8.0 | | Descriptor: | pancreatic ribonuclease | | Authors: | Berisio, R, Sica, F, Lamzin, V.S, Wilson, K.S, Zagari, A, Mazzarella, L. | | Deposit date: | 2001-11-19 | | Release date: | 2001-12-19 | | Last modified: | 2023-08-16 | | Method: | X-RAY DIFFRACTION (1.15 Å) | | Cite: | Atomic resolution structures of ribonuclease A at six pH values.
Acta Crystallogr.,Sect.D, 58, 2002
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3DIB
 | | Crystal structure of bovine pancreatic ribonuclease A variant (I106A) | | Descriptor: | CHLORIDE ION, Ribonuclease pancreatic, SULFATE ION | | Authors: | Kurpiewska, K, Font, J, Ribo, M, Vilanova, M, Lewinski, K. | | Deposit date: | 2008-06-20 | | Release date: | 2008-07-15 | | Last modified: | 2023-11-01 | | Method: | X-RAY DIFFRACTION (1.4 Å) | | Cite: | X-ray crystallographic studies of RNase A variants engineered at the most destabilizing positions of the main hydrophobic core: further insight into protein stability
Proteins, 77, 2009
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