1YV4
X-ray structure of M23L onconase at 100K
Summary for 1YV4
Entry DOI | 10.2210/pdb1yv4/pdb |
Related | 1YV6 1YV7 |
Descriptor | P-30 protein, SULFATE ION (3 entities in total) |
Functional Keywords | small conformational changes, onconase thermal stability, ribonucleases, antitumor action, dynamics, hydrolase |
Biological source | Rana pipiens (northern leopard frog) |
Total number of polymer chains | 1 |
Total formula weight | 12115.80 |
Authors | Merlino, A.,Mazzarella, L.,Carannante, A.,Di Fiore, A.,Di Donato, A.,Notomista, E.,Sica, F. (deposition date: 2005-02-15, release date: 2005-03-01, Last modification date: 2023-10-25) |
Primary citation | Merlino, A.,Mazzarella, L.,Carannante, A.,Di Fiore, A.,Di Donato, A.,Notomista, E.,Sica, F. The Importance of Dynamic Effects on the Enzyme Activity: X-RAY STRUCTURE AND MOLECULAR DYNAMICS OF ONCONASE MUTANTS J.Biol.Chem., 280:17953-17960, 2005 Cited by PubMed: 15728177DOI: 10.1074/jbc.M501339200 PDB entries with the same primary citation |
Experimental method | X-RAY DIFFRACTION (1.51 Å) |
Structure validation
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