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3O6X
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BU of 3o6x by Molmil
Crystal Structure of the type III Glutamine Synthetase from Bacteroides fragilis
Descriptor: ADENOSINE-5'-DIPHOSPHATE, CHLORIDE ION, Glutamine synthetase, ...
Authors:van Rooyen, J.M, Belrhali, H, Abratt, V.R, Sewell, B.T.
Deposit date:2010-07-29
Release date:2011-03-09
Last modified:2024-02-21
Method:X-RAY DIFFRACTION (3.5 Å)
Cite:Crystal Structure of Type III Glutamine Synthetase: Surprising Reversal of the Inter-Ring Interface.
Structure, 19, 2011
1JQ7
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BU of 1jq7 by Molmil
HCMV protease dimer-interface mutant, S225Y complexed to Inhibitor BILC 408
Descriptor: ASSEMBLIN, N-(6-aminohexanoyl)-3-methyl-L-valyl-3-methyl-L-valyl-N~1~-[(2S,3S)-3-hydroxy-4-oxo-4-{[(1R)-1-phenylpropyl]amino}butan-2-yl]-N~4~,N~4~-dimethyl-L-aspartamide
Authors:Batra, R, Khayat, R, Tong, L.
Deposit date:2001-08-03
Release date:2001-09-12
Last modified:2024-03-13
Method:X-RAY DIFFRACTION (3 Å)
Cite:Molecular mechanism for dimerization to regulate the catalytic activity of human cytomegalovirus protease.
Nat.Struct.Biol., 8, 2001
5KER
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BU of 5ker by Molmil
Deer mouse recombinant hemoglobin from high altitude species
Descriptor: Alpha-globin, Beta globin, PROTOPORPHYRIN IX CONTAINING FE
Authors:Inoguchi, N, Natarajan, C, Storz, J.F, Moriyama, H.
Deposit date:2016-06-10
Release date:2017-04-05
Last modified:2023-09-27
Method:X-RAY DIFFRACTION (2.202 Å)
Cite:Alteration of the alpha 1 beta 2/ alpha 2 beta 1 subunit interface contributes to the increased hemoglobin-oxygen affinity of high-altitude deer mice.
PLoS ONE, 12, 2017
8ED3
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BU of 8ed3 by Molmil
Structure of a nanoparticle with icosahedral symmetry
Descriptor: Designed I3-01 icosahedron
Authors:McCarthy, S, Gonen, S.
Deposit date:2022-09-02
Release date:2023-01-11
Method:ELECTRON MICROSCOPY (3.5 Å)
Cite:Improved interface packing and design opportunities revealed by CryoEM analysis of a designed protein nanocage.
Heliyon, 8, 2022
5KH5
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BU of 5kh5 by Molmil
Crystal Structure of Steptococcus pneumoniae Undecaprenyl pyrophosphate Synthase (UPPS) IN COMPLEX WITH ~{N}-(3-azanyl-3-oxidanylidene-propyl)-5-(1-benzothiophen-5-yl)-1-(phenylmethyl)-~{N}-[(4-propan-2-yloxyphenyl)methyl]pyrazole-4-carboxamide
Descriptor: Isoprenyl transferase, ~{N}-(3-azanyl-3-oxidanylidene-propyl)-5-(1-benzothiophen-5-yl)-1-(phenylmethyl)-~{N}-[(4-propan-2-yloxyphenyl)methyl]pyrazole-4-carboxamide
Authors:Concha, N.O.
Deposit date:2016-06-14
Release date:2016-07-20
Last modified:2024-03-06
Method:X-RAY DIFFRACTION (2.63 Å)
Cite:Discovery and Characterization of a Class of Pyrazole Inhibitors of Bacterial Undecaprenyl Pyrophosphate Synthase.
J.Med.Chem., 59, 2016
3Q9U
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BU of 3q9u by Molmil
In silico and in vitro co-evolution of a high affinity complementary protein-protein interface
Descriptor: COENZYME A, CoA binding protein, consensus ankyrin repeat
Authors:Karanicolas, J, Corn, J.E, Chen, I, Joachimiak, L.A, Dym, O, Chung, S, Albeck, S, Unger, T, Hu, W, Liu, G, Delbecq, S, Montelione, G.T, Spiegel, C, Liu, D, Baker, D, Israel Structural Proteomics Center (ISPC)
Deposit date:2011-01-10
Release date:2011-04-20
Last modified:2023-09-13
Method:X-RAY DIFFRACTION (2.3 Å)
Cite:A de novo protein binding pair by computational design and directed evolution.
Mol.Cell, 42, 2011
3HPG
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BU of 3hpg by Molmil
Visna virus integrase (residues 1-219) in complex with LEDGF IBD: examples of open integrase dimer-dimer interfaces
Descriptor: Integrase, PC4 and SFRS1-interacting protein, ZINC ION
Authors:Hare, S, Labeja, A, Cherepanov, P.
Deposit date:2009-06-04
Release date:2009-07-28
Last modified:2023-11-01
Method:X-RAY DIFFRACTION (3.28 Å)
Cite:Structural basis for functional tetramerization of lentiviral integrase
Plos Pathog., 5, 2009
1THG
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BU of 1thg by Molmil
1.8 ANGSTROMS REFINED STRUCTURE OF THE LIPASE FROM GEOTRICHUM CANDIDUM
Descriptor: 2-acetamido-2-deoxy-alpha-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, ...
Authors:Schrag, J.D, Cygler, M.
Deposit date:1992-07-28
Release date:1993-10-31
Last modified:2020-07-29
Method:X-RAY DIFFRACTION (1.8 Å)
Cite:1.8 A refined structure of the lipase from Geotrichum candidum.
J.Mol.Biol., 230, 1993
7V6W
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BU of 7v6w by Molmil
Crystal structure of heterohexameric Sa2YoeB-Sa2YefM complex bound to 26bp-DNA
Descriptor: Antitoxin, DNA (25-MER), DNA (26-MER), ...
Authors:Xue, L, Khan, M.H, Yue, J.
Deposit date:2021-08-20
Release date:2021-12-15
Last modified:2023-11-29
Method:X-RAY DIFFRACTION (2.55 Å)
Cite:The two paralogous copies of the YoeB-YefM toxin-antitoxin module in Staphylococcus aureus differ in DNA binding and recognition patterns.
J.Biol.Chem., 298, 2022
7V5Z
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BU of 7v5z by Molmil
Crystal structure of heterotetrameric complex of Sa2YoeB-Sa2YefM toxin-antitoxin from Staphylococcus aureus
Descriptor: Antitoxin, Putative mRNA interferase YoeB
Authors:Xue, L, Khan, M.H, Yue, J.
Deposit date:2021-08-18
Release date:2021-12-15
Last modified:2023-11-29
Method:X-RAY DIFFRACTION (1.99 Å)
Cite:The two paralogous copies of the YoeB-YefM toxin-antitoxin module in Staphylococcus aureus differ in DNA binding and recognition patterns.
J.Biol.Chem., 298, 2022
8EB1
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BU of 8eb1 by Molmil
Chim2 - Intragenic antimicrobial peptide
Descriptor: Unconventional myosin-Ih, Transcription activator BRG1 intragenic antimicrobial chimeric peptide
Authors:de Freitas, T.V, Oliveira, A.L, Santos, M.A, Brand, G.D.
Deposit date:2022-08-30
Release date:2023-03-01
Last modified:2024-05-15
Method:SOLUTION NMR
Cite:Release of immunomodulatory peptides at bacterial membrane interfaces as a novel strategy to fight microorganisms.
J.Biol.Chem., 299, 2023
5KH4
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BU of 5kh4 by Molmil
Crystal Structure of Steptococcus pneumoniae Undecaprenyl pyrophosphate Synthase (UPPS) with FARNESYL DIPHOSPHATE
Descriptor: FARNESYL DIPHOSPHATE, Isoprenyl transferase
Authors:Concha, N.O.
Deposit date:2016-06-14
Release date:2016-07-20
Last modified:2024-03-06
Method:X-RAY DIFFRACTION (3.2 Å)
Cite:Discovery and Characterization of a Class of Pyrazole Inhibitors of Bacterial Undecaprenyl Pyrophosphate Synthase.
J.Med.Chem., 59, 2016
5KH2
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BU of 5kh2 by Molmil
Crystal Structure of Steptococcus pneumoniae Undecaprenyl pyrophosphate Synthase (UPPS)
Descriptor: Isoprenyl transferase
Authors:Concha, N.O.
Deposit date:2016-06-14
Release date:2016-07-20
Last modified:2024-03-06
Method:X-RAY DIFFRACTION (2.3 Å)
Cite:Discovery and Characterization of a Class of Pyrazole Inhibitors of Bacterial Undecaprenyl Pyrophosphate Synthase.
J.Med.Chem., 59, 2016
5L19
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BU of 5l19 by Molmil
Crystal Structure of a human FasL mutant
Descriptor: SULFATE ION, Tumor necrosis factor ligand superfamily member 6, ZINC ION
Authors:Liu, W, Bonanno, J.B, Almo, S.C.
Deposit date:2016-07-28
Release date:2016-09-07
Last modified:2023-10-04
Method:X-RAY DIFFRACTION (2 Å)
Cite:Crystal Structure of the Complex of Human FasL and Its Decoy Receptor DcR3.
Structure, 24, 2016
7V5Y
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BU of 7v5y by Molmil
Crystal structure of hexameric complex of Sa2YoeB-Sa2YefM toxin-antitoxin from Staphylococcus aureus
Descriptor: Antitoxin, Putative mRNA interferase YoeB
Authors:Xue, L, Khan, M.H, Yue, J.
Deposit date:2021-08-18
Release date:2021-12-15
Last modified:2023-11-29
Method:X-RAY DIFFRACTION (2.25 Å)
Cite:The two paralogous copies of the YoeB-YefM toxin-antitoxin module in Staphylococcus aureus differ in DNA binding and recognition patterns.
J.Biol.Chem., 298, 2022
4NHV
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BU of 4nhv by Molmil
Crystal structure of B. anthracis DHPS with interfacial compound 4: 5-(trifluoromethyl)-1,2-benzoxazol-3-amine
Descriptor: 5-(trifluoromethyl)-1,2-benzoxazol-3-amine, Dihydropteroate synthase, SULFATE ION
Authors:Hammoudeh, D.I, White, S.W.
Deposit date:2013-11-05
Release date:2014-05-14
Last modified:2023-09-20
Method:X-RAY DIFFRACTION (1.992 Å)
Cite:Identification and characterization of an allosteric inhibitory site on dihydropteroate synthase.
Acs Chem.Biol., 9, 2014
3Q9N
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BU of 3q9n by Molmil
In silico and in vitro co-evolution of a high affinity complementary protein-protein interface
Descriptor: CARBAMOYL SARCOSINE, COENZYME A, CoA binding protein, ...
Authors:Karanicolas, J, Corn, J.E, Chen, I, Joachimiak, L.A, Dym, O, Chung, S, Albeck, S, Unger, T, Hu, W, Liu, G, Delbecq, S, Montelione, G.T, Spiegel, C, Liu, D, Baker, D, Israel Structural Proteomics Center (ISPC)
Deposit date:2011-01-09
Release date:2011-04-27
Last modified:2023-09-13
Method:X-RAY DIFFRACTION (2 Å)
Cite:A de novo protein binding pair by computational design and directed evolution.
Mol.Cell, 42, 2011
6NG3
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BU of 6ng3 by Molmil
Crystal structure of human CD160 and HVEM complex
Descriptor: 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, CD160 antigen,Tumor necrosis factor receptor superfamily member 14, MAGNESIUM ION, ...
Authors:Liu, W, Bonanno, J, Almo, S.C.
Deposit date:2018-12-21
Release date:2019-07-03
Last modified:2023-10-11
Method:X-RAY DIFFRACTION (2.88 Å)
Cite:Structural Basis of CD160:HVEM Recognition.
Structure, 27, 2019
3QBQ
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BU of 3qbq by Molmil
Crystal structure of extracellular domains of mouse RANK-RANKL complex
Descriptor: Tumor necrosis factor ligand superfamily member 11, Tumor necrosis factor receptor superfamily member 11A
Authors:Ta, H.M, Nguyen, G.T.T, Jin, H.M, Choi, J.K, Park, H, Kim, N.S, Hwang, H.Y, Kim, K.K.
Deposit date:2011-01-13
Release date:2011-03-02
Last modified:2023-11-01
Method:X-RAY DIFFRACTION (2.5 Å)
Cite:Structure-based development of a receptor activator of nuclear factor-kappaB ligand (RANKL) inhibitor peptide and molecular basis for osteopetrosis
Proc.Natl.Acad.Sci.USA, 107, 2010
1DN2
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BU of 1dn2 by Molmil
FC FRAGMENT OF HUMAN IGG1 IN COMPLEX WITH AN ENGINEERED 13 RESIDUE PEPTIDE DCAWHLGELVWCT-NH2
Descriptor: ENGINEERED PEPTIDE, IMMUNOGLOBULIN LAMBDA HEAVY CHAIN, beta-D-galactopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose-(1-2)-alpha-D-mannopyranose-(1-6)-[alpha-D-mannopyranose-(1-3)]beta-D-mannopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-[alpha-L-fucopyranose-(1-6)]2-acetamido-2-deoxy-beta-D-glucopyranose, ...
Authors:DeLano, W.L, Ultsch, M.H, de Vos, A.M, Wells, J.A.
Deposit date:1999-12-15
Release date:2000-05-17
Last modified:2020-07-29
Method:X-RAY DIFFRACTION (2.7 Å)
Cite:Convergent solutions to binding at a protein-protein interface.
Science, 287, 2000
1JUN
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BU of 1jun by Molmil
NMR STUDY OF C-JUN HOMODIMER
Descriptor: C-JUN HOMODIMER
Authors:Junius, F.K, O'Donoghue, S.I, Nilges, M, King, G.F.
Deposit date:1995-12-19
Release date:1996-06-20
Last modified:2022-02-23
Method:SOLUTION NMR
Cite:High resolution NMR solution structure of the leucine zipper domain of the c-Jun homodimer.
J.Biol.Chem., 271, 1996
2JK2
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BU of 2jk2 by Molmil
STRUCTURAL BASIS OF HUMAN TRIOSEPHOSPHATE ISOMERASE DEFICIENCY. CRYSTAL STRUCTURE OF THE WILD TYPE ENZYME.
Descriptor: TRIOSEPHOSPHATE ISOMERASE
Authors:Rodriguez-Almazan, C, Arreola-Alemon, R, Rodriguez-Larrea, D, Aguirre-Lopez, B, De Gomez-Puyou, M.T, Perez-Montfort, R, Costas, M, Gomez-Puyou, A, Torres-Larios, A.
Deposit date:2008-06-22
Release date:2008-07-01
Last modified:2023-12-13
Method:X-RAY DIFFRACTION (1.7 Å)
Cite:Structural Basis of Human Triosephosphate Isomerase Deficiency: Mutation E104D is Related to Alterations of a Conserved Water Network at the Dimer Interface.
J.Biol.Chem., 283, 2008
6HCM
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BU of 6hcm by Molmil
Structure of the rabbit collided di-ribosome (stalled monosome)
Descriptor: 18S ribosomal RNA, 28S ribosomal RNA, 40S ribosomal protein S12, ...
Authors:Juszkiewicz, S, Chandrasekaran, V, Lin, Z, Kraatz, S, Ramakrishnan, V, Hegde, R.S.
Deposit date:2018-08-15
Release date:2018-10-17
Last modified:2024-05-15
Method:ELECTRON MICROSCOPY (6.8 Å)
Cite:ZNF598 Is a Quality Control Sensor of Collided Ribosomes.
Mol. Cell, 72, 2018
6HCF
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BU of 6hcf by Molmil
Structure of the rabbit 80S ribosome stalled on globin mRNA at the stop codon
Descriptor: 18S ribosomal RNA, 28S ribosomal RNA, 40S ribosomal protein S12, ...
Authors:Juszkiewicz, S, Chandrasekaran, V, Lin, Z, Kraatz, S, Ramakrishnan, V, Hegde, R.S.
Deposit date:2018-08-14
Release date:2018-10-17
Last modified:2024-05-15
Method:ELECTRON MICROSCOPY (3.9 Å)
Cite:ZNF598 Is a Quality Control Sensor of Collided Ribosomes.
Mol. Cell, 72, 2018
7PD3
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BU of 7pd3 by Molmil
Structure of the human mitoribosomal large subunit in complex with NSUN4.MTERF4.GTPBP7 and MALSU1.L0R8F8.mt-ACP
Descriptor: 16S rRNA, 39S ribosomal protein L10, mitochondrial, ...
Authors:Chandrasekaran, V, Desai, N, Burton, N.O, Yang, H, Price, J, Miska, E.A, Ramakrishnan, V.
Deposit date:2021-08-04
Release date:2021-11-17
Method:ELECTRON MICROSCOPY (3.4 Å)
Cite:Visualizing formation of the active site in the mitochondrial ribosome.
Elife, 10, 2021

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數據於2024-07-10公開中

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