PDB: 13252 resultsInfo pagesStatus searchChemie searchBIRD

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7D7D	CryoEM structure of gp45-dependent transcription activation complex Descriptor: DNA (nontemplate strand), DNA (template strand), DNA polymerase clamp, ... Authors: Shi, J, Wen, A, Jin, S, Feng, Y. Deposit date: 2020-10-03 Release date: 2021-01-20 Last modified: 2024-03-27 Method: ELECTRON MICROSCOPY (4.5 Å) Cite: Transcription activation by a sliding clamp. Nat Commun, 12, 2021
5NGM	2.9S structure of the 70S ribosome composing the S. aureus 100S complex Descriptor: 16S ribosomal RNA, 23S Ribosomal RNA, 30S ribosomal protein S10, ... Authors: Matzov, D, Aibara, S, Zimmerman, E, Bashan, A, Amunts, A, Yonath, A. Deposit date: 2017-03-18 Release date: 2017-10-04 Last modified: 2018-11-28 Method: ELECTRON MICROSCOPY (2.9 Å) Cite: The cryo-EM structure of hibernating 100S ribosome dimer from pathogenic Staphylococcus aureus. Nat Commun, 8, 2017
8FVR	CryoEM structure of E.coli transcription elongation complex Descriptor: DNA (53-MER), DNA-directed RNA polymerase subunit alpha, DNA-directed RNA polymerase subunit beta, ... Authors: Duan, W, Serganov, A. Deposit date: 2023-01-19 Release date: 2023-04-05 Last modified: 2024-06-19 Method: ELECTRON MICROSCOPY (2.42 Å) Cite: Control of transcription elongation and DNA repair by alarmone ppGpp. Nat.Struct.Mol.Biol., 30, 2023
8FVW	CryoEM structure of E.coli transcription elongation complex bound to ppGpp Descriptor: DNA (53-MER), DNA-directed RNA polymerase subunit alpha, DNA-directed RNA polymerase subunit beta, ... Authors: Duan, W, Serganov, A. Deposit date: 2023-01-19 Release date: 2023-04-05 Last modified: 2024-06-19 Method: ELECTRON MICROSCOPY (2.1 Å) Cite: Control of transcription elongation and DNA repair by alarmone ppGpp. Nat.Struct.Mol.Biol., 30, 2023
5KT2	Teranry complex of human DNA polymerase iota(26-445) inserting dCMPNPP opposite template G in the presence of Mg2+ Descriptor: 2'-deoxy-5'-O-[(R)-hydroxy{[(R)-hydroxy(phosphonooxy)phosphoryl]amino}phosphoryl]cytidine, DNA (5'-D(*CP*TP*GP*GP*GP*GP*TP*CP*CP*T)-3'), DNA (5'-D(P*AP*GP*GP*AP*CP*CP*C)-3'), ... Authors: Choi, J.Y, Patra, A, Yeom, M, Lee, Y.S, Zhang, Q, Egli, M, Guengerich, F.P. Deposit date: 2016-07-11 Release date: 2016-08-31 Last modified: 2024-03-06 Method: X-RAY DIFFRACTION (2.488 Å) Cite: Kinetic and Structural Impact of Metal Ions and Genetic Variations on Human DNA Polymerase iota. J.Biol.Chem., 291, 2016
5KT7	Teranry complex of human DNA polymerase iota(1-445) inserting dCMPNPP opposite template G in the presence of Mn2+ Descriptor: 2'-deoxy-5'-O-[(R)-hydroxy{[(R)-hydroxy(phosphonooxy)phosphoryl]amino}phosphoryl]cytidine, DNA (5'-D(P*AP*GP*GP*AP*CP*CP*C)-3'), DNA (5'-D(P*TP*GP*GP*GP*GP*TP*CP*CP*T)-3'), ... Authors: Choi, J.Y, Patra, A, Yeom, M, Lee, Y.S, Zhang, Q, Egli, M, Guengerich, F.P. Deposit date: 2016-07-11 Release date: 2016-08-31 Last modified: 2024-03-06 Method: X-RAY DIFFRACTION (3.151 Å) Cite: Kinetic and Structural Impact of Metal Ions and Genetic Variations on Human DNA Polymerase iota. J.Biol.Chem., 291, 2016
5KT3	Teranry complex of human DNA polymerase iota(26-445) inserting dCMPNPP opposite template G in the presence of Mn2+ Descriptor: 2'-deoxy-5'-O-[(R)-hydroxy{[(R)-hydroxy(phosphonooxy)phosphoryl]amino}phosphoryl]cytidine, DNA (5'-D(*CP*TP*GP*GP*GP*GP*TP*CP*CP*T)-3'), DNA (5'-D(P*AP*GP*GP*AP*CP*CP*C)-3'), ... Authors: Choi, J.Y, Patra, A, Yeom, M, Lee, Y.S, Zhang, Q, Egli, M, Guengerich, F.P. Deposit date: 2016-07-11 Release date: 2016-08-31 Last modified: 2024-03-06 Method: X-RAY DIFFRACTION (2.64 Å) Cite: Kinetic and Structural Impact of Metal Ions and Genetic Variations on Human DNA Polymerase iota. J.Biol.Chem., 291, 2016
6R9G	Structural basis of transcription inhibition by the DNA mimic Ocr protein of bacteriophage T7 Descriptor: DNA-directed RNA polymerase subunit alpha, DNA-directed RNA polymerase subunit beta, DNA-directed RNA polymerase subunit beta', ... Authors: Ye, F.Z, Zhang, X.D. Deposit date: 2019-04-03 Release date: 2020-02-26 Last modified: 2024-05-22 Method: ELECTRON MICROSCOPY (3.7 Å) Cite: Structural basis of transcription inhibition by the DNA mimic protein Ocr of bacteriophage T7. Elife, 9, 2020
9ICC	DNA POLYMERASE BETA (E.C.2.7.7.7)/DNA COMPLEX + 2'-DEOXYADENOSINE-5'-TRIPHOSPHATE, SOAKED IN THE PRESENCE OF DATP AND CRCL3 Descriptor: 2'-DEOXYADENOSINE 5'-TRIPHOSPHATE, CHROMIUM ION, DNA (5'-D(*CP*AP*TP*TP*AP*GP*AP*A)-3'), ... Authors: Pelletier, H, Sawaya, M.R. Deposit date: 1995-12-15 Release date: 1995-12-15 Last modified: 2023-08-02 Method: X-RAY DIFFRACTION (3.1 Å) Cite: Characterization of the metal ion binding helix-hairpin-helix motifs in human DNA polymerase beta by X-ray structural analysis. Biochemistry, 35, 1996
9ICG	DNA POLYMERASE BETA (POL B) (E.C.2.7.7.7) COMPLEXED WITH SEVEN BASE PAIRS OF DNA; SOAKED IN THE PRESENCE OF DCTP (1 MILLIMOLAR) AND ZNCL2 (1 MILLIMOLAR) Descriptor: 2'-DEOXYCYTIDINE-5'-TRIPHOSPHATE, DNA (5'-D(*CP*AP*TP*TP*AP*GP*AP*A)-3'), DNA (5'-D(*TP*CP*TP*AP*AP*TP*G)-3'), ... Authors: Pelletier, H, Sawaya, M.R. Deposit date: 1995-12-15 Release date: 1996-11-15 Last modified: 2023-08-02 Method: X-RAY DIFFRACTION (3 Å) Cite: Characterization of the metal ion binding helix-hairpin-helix motifs in human DNA polymerase beta by X-ray structural analysis. Biochemistry, 35, 1996
9ICL	DNA POLYMERASE BETA (E.C.2.7.7.7)/DNA COMPLEX, SOAKED IN THE PRESENCE OF PYROPHOSPHATE AND MNCL2 Descriptor: DNA (5'-D(*CP*AP*GP*AP*TP*G)-3'), DNA (5'-D(*CP*AP*TP*CP*TP*GP*T)-3'), MANGANESE (II) ION, ... Authors: Pelletier, H, Sawaya, M.R. Deposit date: 1996-01-04 Release date: 1996-11-15 Last modified: 2023-08-02 Method: X-RAY DIFFRACTION (2.8 Å) Cite: Characterization of the metal ion binding helix-hairpin-helix motifs in human DNA polymerase beta by X-ray structural analysis Biochemistry, 35, 1996
9ICH	DNA POLYMERASE BETA (POL B) (E.C.2.7.7.7) COMPLEXED WITH SEVEN BASE PAIRS OF DNA; SOAKED IN THE PRESENCE OF DGTP (1 MILLIMOLAR) AND ZNCL2 (1 MILLIMOLAR) Descriptor: 2'-DEOXYGUANOSINE-5'-TRIPHOSPHATE, DNA (5'-D(*CP*AP*TP*TP*AP*GP*AP*A)-3'), DNA (5'-D(*TP*CP*TP*AP*AP*TP*G)-3'), ... Authors: Pelletier, H, Sawaya, M.R. Deposit date: 1995-12-15 Release date: 1996-11-15 Last modified: 2023-08-02 Method: X-RAY DIFFRACTION (2.9 Å) Cite: Characterization of the metal ion binding helix-hairpin-helix motifs in human DNA polymerase beta by X-ray structural analysis. Biochemistry, 35, 1996
9ICA	DNA POLYMERASE BETA (E.C.2.7.7.7)/DNA COMPLEX + 2'-DEOXYADENOSINE-5'-O-(1-THIOTRIPHOSPHATE), SOAKED IN THE PRESENCE OF DATP(ALPHA)S AND MNCL2 Descriptor: 2'-DEOXYADENOSINE 5'-O-(1-THIOTRIPHOSPHATE), DNA (5'-D(*CP*AP*TP*TP*AP*GP*AP*A)-3'), DNA (5'-D(*TP*CP*TP*AP*AP*TP*G)-3'), ... Authors: Pelletier, H, Sawaya, M.R. Deposit date: 1995-12-15 Release date: 1995-12-15 Last modified: 2023-08-02 Method: X-RAY DIFFRACTION (3 Å) Cite: Characterization of the metal ion binding helix-hairpin-helix motifs in human DNA polymerase beta by X-ray structural analysis. Biochemistry, 35, 1996
9ICE	DNA POLYMERASE BETA (POL B) (E.C.2.7.7.7) COMPLEXED WITH SEVEN BASE PAIRS OF DNA; SOAKED IN THE PRESENCE OF DATP (1 MILLIMOLAR) AND CUCL2 (0.1 MILLIMOLAR) Descriptor: DNA (5'-D(*CP*AP*TP*TP*AP*GP*AP*A)-3'), DNA (5'-D(*TP*CP*TP*AP*AP*TP*G)-3'), PROTEIN (DNA POLYMERASE BETA (E.C.2.7.7.7)), ... Authors: Pelletier, H, Sawaya, M.R. Deposit date: 1995-12-15 Release date: 1996-11-15 Last modified: 2023-08-02 Method: X-RAY DIFFRACTION (3.3 Å) Cite: Characterization of the metal ion binding helix-hairpin-helix motifs in human DNA polymerase beta by X-ray structural analysis. Biochemistry, 35, 1996
9ICJ	DNA POLYMERASE BETA (POL B) (E.C.2.7.7.7) COMPLEXED WITH SEVEN BASE PAIRS OF DNA Descriptor: DNA (5'-D(*CP*AP*TP*TP*AP*GP*AP*A)-3'), DNA (5'-D(*TP*CP*TP*AP*AP*TP*G)-3'), PROTEIN (DNA POLYMERASE BETA (E.C.2.7.7.7)), ... Authors: Pelletier, H, Sawaya, M.R. Deposit date: 1995-12-15 Release date: 1996-11-15 Last modified: 2023-08-02 Method: X-RAY DIFFRACTION (3.1 Å) Cite: Characterization of the metal ion binding helix-hairpin-helix motifs in human DNA polymerase beta by X-ray structural analysis Biochemistry, 35, 1996
9ICI	DNA POLYMERASE BETA (POL B) (E.C.2.7.7.7) COMPLEXED WITH SEVEN BASE PAIRS OF DNA; SOAKED IN THE PRESENCE OF DTTP (1 MILLIMOLAR) AND ZNCL2 (1 MILLIMOLAR) Descriptor: DNA (5'-D(*CP*AP*TP*TP*AP*GP*AP*A)-3'), DNA (5'-D(*TP*CP*TP*AP*AP*TP*GP*T)-3'), PROTEIN (DNA POLYMERASE BETA (E.C.2.7.7.7)), ... Authors: Pelletier, H, Sawaya, M.R. Deposit date: 1995-12-15 Release date: 1996-11-15 Last modified: 2023-08-02 Method: X-RAY DIFFRACTION (3.1 Å) Cite: Characterization of the metal ion binding helix-hairpin-helix motifs in human DNA polymerase beta by X-ray structural analysis. Biochemistry, 35, 1996
9ICB	DNA POLYMERASE BETA (E.C.2.7.7.7)/DNA COMPLEX + 2'-DEOXYADENOSINE-5'-TRIPHOSPHATE, SOAKED IN THE PRESENCE OF DATP AND COCL2 Descriptor: 2'-DEOXYADENOSINE 5'-TRIPHOSPHATE, COBALT (II) ION, DNA (5'-D(*CP*AP*TP*TP*AP*GP*AP*A)-3'), ... Authors: Pelletier, H, Sawaya, M.R. Deposit date: 1995-12-15 Release date: 1995-12-15 Last modified: 2023-08-02 Method: X-RAY DIFFRACTION (3.2 Å) Cite: Characterization of the metal ion binding helix-hairpin-helix motifs in human DNA polymerase beta by X-ray structural analysis. Biochemistry, 35, 1996
7W5Y	Cryo-EM structure of SoxS-dependent transcription activation complex with fpr promoter DNA Descriptor: DNA-directed RNA polymerase subunit alpha, DNA-directed RNA polymerase subunit beta, DNA-directed RNA polymerase subunit beta', ... Authors: Lin, W, Feng, Y. Deposit date: 2021-11-30 Release date: 2022-10-26 Last modified: 2024-06-26 Method: ELECTRON MICROSCOPY (4.2 Å) Cite: Structural basis of three different transcription activation strategies adopted by a single regulator SoxS. Nucleic Acids Res., 50, 2022
7W5W	Cryo-EM structure of SoxS-dependent transcription activation complex with micF promoter DNA Descriptor: DNA-directed RNA polymerase subunit alpha, DNA-directed RNA polymerase subunit beta, DNA-directed RNA polymerase subunit beta', ... Authors: Lin, W, Feng, Y. Deposit date: 2021-11-30 Release date: 2022-10-26 Last modified: 2024-06-26 Method: ELECTRON MICROSCOPY (4.55 Å) Cite: Structural basis of three different transcription activation strategies adopted by a single regulator SoxS. Nucleic Acids Res., 50, 2022
7W5X	Cryo-EM structure of SoxS-dependent transcription activation complex with zwf promoter DNA Descriptor: DNA-directed RNA polymerase subunit alpha, DNA-directed RNA polymerase subunit beta, DNA-directed RNA polymerase subunit beta', ... Authors: Lin, W, Feng, Y, Shi, J. Deposit date: 2021-11-30 Release date: 2022-10-26 Last modified: 2024-06-26 Method: ELECTRON MICROSCOPY (3.4 Å) Cite: Structural basis of three different transcription activation strategies adopted by a single regulator SoxS. Nucleic Acids Res., 50, 2022
6ZOJ	SARS-CoV-2-Nsp1-40S complex, composite map Descriptor: 18S ribosomal RNA, 40S ribosomal protein S10, 40S ribosomal protein S11, ... Authors: Schubert, K, Karousis, E.D, Jomaa, A, Scaiola, A, Echeverria, B, Gurzeler, L.-A, Leibundgut, M.L, Thiel, V, Muehlemann, O, Ban, N. Deposit date: 2020-07-07 Release date: 2020-07-22 Last modified: 2021-02-10 Method: ELECTRON MICROSCOPY (2.8 Å) Cite: SARS-CoV-2 Nsp1 binds the ribosomal mRNA channel to inhibit translation. Nat.Struct.Mol.Biol., 27, 2020
8HK1	The cryo-EM structure of human pre-17S U2 snRNP Descriptor: ATP-dependent RNA helicase DDX42, HIV Tat-specific factor 1, PHD finger-like domain-containing protein 5A, ... Authors: Zhang, X, Zhan, X, Shi, Y. Deposit date: 2022-11-24 Release date: 2023-03-08 Last modified: 2023-08-16 Method: ELECTRON MICROSCOPY (2.7 Å) Cite: Mechanisms of the RNA helicases DDX42 and DDX46 in human U2 snRNP assembly. Nat Commun, 14, 2023
5E17	T. thermophilus transcription initiation complex having a RRR discriminator sequence and a nontemplate-strand length corresponding to TSS selection at position 7 (RPo-GGG-7) Descriptor: DNA (27-MER), DNA (5'-D(*CP*CP*T*GP*CP*AP*TP*CP*CP*GP*TP*GP*AP*GP*TP*CP*GP*AP*GP*GP*G)-3'), DNA-directed RNA polymerase subunit alpha, ... Authors: Zhang, Y, Ebright, R.H. Deposit date: 2015-09-29 Release date: 2016-03-09 Last modified: 2023-09-27 Method: X-RAY DIFFRACTION (3.2 Å) Cite: Multiplexed protein-DNA cross-linking: Scrunching in transcription start site selection. Science, 351, 2016
6WYB	RTX (Reverse Transcription Xenopolymerase) in complex with an RNA/DNA hybrid Descriptor: 1,2-ETHANEDIOL, 3,3',3''-phosphanetriyltripropanoic acid, DNA polymerase, ... Authors: Choi, W.S, He, P, Pothukuchy, A, Gollihar, J, Ellington, A.D, Yang, W. Deposit date: 2020-05-12 Release date: 2020-08-19 Last modified: 2023-10-18 Method: X-RAY DIFFRACTION (2.5 Å) Cite: How a B family DNA polymerase has been evolved to copy RNA. Proc.Natl.Acad.Sci.USA, 117, 2020
5E18	T. thermophilus transcription initiation complex having a YYY discriminator sequence and a nontemplate-strand length corresponding to TSS selection at position 8 (RPo-CCC-8) Descriptor: DNA (28-MER), DNA (5'-D(*CP*CP*T*GP*CP*AP*TP*CP*CP*GP*TP*GP*AP*GP*TP*CP*GP*AP*GP*GP*G)-3'), DNA-directed RNA polymerase subunit alpha, ... Authors: Zhang, Y, Ebright, R.H. Deposit date: 2015-09-29 Release date: 2016-03-09 Last modified: 2023-09-27 Method: X-RAY DIFFRACTION (3.3 Å) Cite: Multiplexed protein-DNA cross-linking: Scrunching in transcription start site selection. Science, 351, 2016

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