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8OW4
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BU of 8ow4 by Molmil
2.75 angstrom crystal structure of human NFAT1 with bound DNA
Descriptor: DNA (5'-D(*AP*AP*CP*TP*AP*TP*TP*TP*TP*TP*CP*CP*AP*GP*C)-3'), DNA (5'-D(*TP*TP*GP*CP*TP*GP*GP*AP*AP*AP*AP*AP*TP*AP*G)-3'), Nuclear factor of activated T-cells, ...
Authors:Lopez-Sagaseta, J, Erausquin, E, Hernandez-Morales, S, Urdiciain, A, Lasarte, J.J, Lozano, T.
Deposit date:2023-04-27
Release date:2023-07-26
Last modified:2024-02-07
Method:X-RAY DIFFRACTION (2.75 Å)
Cite:2.75 angstrom crystal structure of human NFAT1 with bound DNA
Not published
2JFF
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BU of 2jff by Molmil
Crystal structure of MurD ligase in complex with D-Glu containing sulfonamide inhibitor
Descriptor: N-[(6-BUTOXYNAPHTHALEN-2-YL)SULFONYL]-D-GLUTAMIC ACID, SULFATE ION, UDP-N-ACETYLMURAMOYLALANINE--D-GLUTAMATE LIGASE
Authors:Kotnik, M, Humljan, J, Contreras-Martel, C, Oblak, M, Kristan, K, Herve, M, Blanot, D, Urleb, U, Gobec, S, Dessen, A, Solmajer, T.
Deposit date:2007-02-01
Release date:2007-05-15
Last modified:2023-12-13
Method:X-RAY DIFFRACTION (1.89 Å)
Cite:Structural and Functional Characterization of Enantiomeric Glutamic Acid Derivatives as Potential Transition State Analogue Inhibitors of Murd Ligase.
J.Mol.Biol., 370, 2007
1RE4
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BU of 1re4 by Molmil
Crystal Structure of Fragment D of BbetaD398A Fibrinogen
Descriptor: 2-acetamido-2-deoxy-beta-D-glucopyranose, CALCIUM ION, Fibrinogen alpha/alpha-E chain, ...
Authors:Kostelansky, M.S, Betts, L, Gorkun, O.V, Lord, S.T.
Deposit date:2003-11-06
Release date:2004-05-25
Last modified:2023-08-23
Method:X-RAY DIFFRACTION (2.7 Å)
Cite:BbetaGlu397 and BbetaAsp398 but not BbetaAsp432 are required for "B:b" interactions.
Biochemistry, 43, 2004
2PEG
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BU of 2peg by Molmil
Crystal structure of Trematomus bernacchii hemoglobin in a partial hemichrome state
Descriptor: Hemoglobin subunit alpha, Hemoglobin subunit beta, PROTOPORPHYRIN IX CONTAINING FE
Authors:Vergara, A, Franzese, M, Merlino, A, Vitagliano, L, Mazzarella, L.
Deposit date:2007-04-03
Release date:2007-07-24
Last modified:2024-10-09
Method:X-RAY DIFFRACTION (1.48 Å)
Cite:Structural characterization of ferric hemoglobins from three antarctic fish species of the suborder notothenioidei.
Biophys.J., 93, 2007
1JPY
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BU of 1jpy by Molmil
Crystal structure of IL-17F
Descriptor: 2-acetamido-2-deoxy-alpha-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, ...
Authors:Hymowitz, S.G, Filvaroff, E.H, Yin, J, Lee, J, Cai, L, Risser, P, Maruoka, M, Mao, W, Foster, J, Kelley, R, Pan, G, Gurney, A.L, de Vos, A.M, Starovasnik, M.A.
Deposit date:2001-08-03
Release date:2001-09-28
Last modified:2020-07-29
Method:X-RAY DIFFRACTION (2.85 Å)
Cite:IL-17s adopt a cystine knot fold: structure and activity of a novel cytokine, IL-17F, and implications for receptor binding.
EMBO J., 20, 2001
2I7B
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BU of 2i7b by Molmil
Structure of the naturally occuring mutant of human ABO(H) Blood group B glycosyltransferase: GTB/A268T
Descriptor: MERCURY (II) ION, alpha 1-3-galactosyltransferase
Authors:Letts, J.A, Evans, S.V.
Deposit date:2006-08-30
Release date:2007-05-22
Last modified:2023-08-30
Method:X-RAY DIFFRACTION (1.99 Å)
Cite:Structural basis for red cell phenotypic changes in newly identified, naturally occurring subgroup mutants of the human blood group B glycosyltransferase.
Transfusion, 47, 2007
2XIU
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BU of 2xiu by Molmil
High resolution structure of MTSL-tagged CylR2.
Descriptor: CYLR2, GLYCEROL, S-[(1-oxyl-2,2,5,5-tetramethyl-2,5-dihydro-1H-pyrrol-3-yl)methyl] methanesulfonothioate
Authors:Gruene, T, Cho, M.-K, Karyagina, I, Kim, H.-Y, Grosse, C, Giller, K, Zweckstetter, M, Becker, S.
Deposit date:2010-07-01
Release date:2011-02-09
Last modified:2023-12-20
Method:X-RAY DIFFRACTION (1.5 Å)
Cite:Integrated Analysis of the Conformation of a Protein-Linked Spin Label by Crystallography, Epr and NMR Spectroscopy.
J.Biomol.NMR, 49, 2011
2WRZ
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BU of 2wrz by Molmil
Crystal structure of an arabinose binding protein with designed serotonin binding site in open, ligand-free state
Descriptor: L-ARABINOSE-BINDING PERIPLASMIC PROTEIN
Authors:Schreier, B, Stumpp, C, Wiesner, S, Hocker, B.
Deposit date:2009-09-03
Release date:2009-10-13
Last modified:2023-12-20
Method:X-RAY DIFFRACTION (2.2 Å)
Cite:The Computational Design of Ligand Binding is not a Solved Problem
Proc.Natl.Acad.Sci.USA, 106, 2009
2YV9
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BU of 2yv9 by Molmil
Crystal structure of the CLIC homologue EXC-4 from c. elegans
Descriptor: CALCIUM ION, Chloride intracellular channel exc-4
Authors:Harrop, S.J, Littler, D.R, Curmi, P.M.G.
Deposit date:2007-04-10
Release date:2008-02-19
Last modified:2023-10-25
Method:X-RAY DIFFRACTION (1.6 Å)
Cite:Comparison of vertebrate and invertebrate CLIC proteins: The crystal structures of Caenorhabditis elegans EXC-4 and Drosophila melanogaster DmCLIC
Proteins, 71, 2007
2YV7
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BU of 2yv7 by Molmil
Crystal structure of the CLIC homolog from drosophila melanogaster
Descriptor: CALCIUM ION, CG10997-PA, IODIDE ION
Authors:Harrop, S.J, Littler, D.R, Curmi, P.M.G.
Deposit date:2007-04-10
Release date:2008-02-19
Last modified:2023-10-25
Method:X-RAY DIFFRACTION (1.7 Å)
Cite:Comparison of vertebrate and invertebrate CLIC proteins: The crystal structures of Caenorhabditis elegans EXC-4 and Drosophila melanogaster DmCLIC
Proteins, 71, 2007
3F9M
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BU of 3f9m by Molmil
Human pancreatic glucokinase in complex with glucose and activator showing a mobile flap
Descriptor: 2-AMINO-4-FLUORO-5-[(1-METHYL-1H-IMIDAZOL-2-YL)SULFANYL]-N-(1,3-THIAZOL-2-YL)BENZAMIDE, Glucokinase, alpha-D-glucopyranose
Authors:Petit, P, Gluais, L, Lagarde, A, Vuillard, L, Boutin, J.A, Ferry, G.
Deposit date:2008-11-14
Release date:2008-12-02
Last modified:2023-11-01
Method:X-RAY DIFFRACTION (1.5 Å)
Cite:The active conformation of human glucokinase is not altered by allosteric activators
Acta Crystallogr.,Sect.D, 67, 2011
3FGU
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BU of 3fgu by Molmil
Catalytic complex of Human Glucokinase
Descriptor: Glucokinase, MAGNESIUM ION, PHOSPHOAMINOPHOSPHONIC ACID-ADENYLATE ESTER, ...
Authors:Petit, P, Lagarde, A, Boutin, J.A, Ferry, G, Vuillard, L.
Deposit date:2008-12-08
Release date:2009-12-15
Last modified:2023-11-01
Method:X-RAY DIFFRACTION (2.15 Å)
Cite:The active conformation of human glucokinase is not altered by allosteric activators
Acta Crystallogr.,Sect.D, 67, 2011
7DXJ
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BU of 7dxj by Molmil
Human 46QHuntingtin-HAP40 complex structure
Descriptor: 40-kDa huntingtin-associated protein, Huntingtin
Authors:Guo, Q, Fernandez-Busnadiego, R.
Deposit date:2021-01-19
Release date:2021-03-24
Last modified:2021-10-06
Method:ELECTRON MICROSCOPY (3.6 Å)
Cite:Pathological polyQ expansion does not alter the conformation of the Huntingtin-HAP40 complex.
Structure, 29, 2021
7DXK
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BU of 7dxk by Molmil
Human 128QHuntingtin-HAP40 complex structure
Descriptor: 40-kDa huntingtin-associated protein, Huntingtin
Authors:Guo, Q, Fernandez-Busnadiego, R.
Deposit date:2021-01-19
Release date:2021-03-24
Last modified:2024-10-16
Method:ELECTRON MICROSCOPY (4.1 Å)
Cite:Pathological polyQ expansion does not alter the conformation of the Huntingtin-HAP40 complex.
Structure, 29, 2021
7EBF
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BU of 7ebf by Molmil
Cryo-EM structure of Isocitrate lyase-1 from Candida albicans
Descriptor: Isocitrate lyase
Authors:Hiragi, K, Nishio, K, Moriyama, S, Hamaguchi, T, Mizoguchi, A, Yonekura, K, Tani, K, Mizushima, T.
Deposit date:2021-03-09
Release date:2021-06-23
Last modified:2024-03-27
Method:ELECTRON MICROSCOPY (2.63 Å)
Cite:Structural insights into the targeting specificity of ubiquitin ligase for S. cerevisiae isocitrate lyase but not C. albicans isocitrate lyase.
J.Struct.Biol., 213, 2021
7EBC
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BU of 7ebc by Molmil
Crystal structure of Isocitrate lyase-1 from Saccaromyces cervisiae
Descriptor: Isocitrate lyase, MAGNESIUM ION, TETRAETHYLENE GLYCOL
Authors:Hiragi, K, Nishio, K, Moriyama, S, Hamaguchi, T, Mizoguchi, A, Yonekura, K, Tani, K, Mizushima, T.
Deposit date:2021-03-09
Release date:2021-06-23
Last modified:2023-11-29
Method:X-RAY DIFFRACTION (2.3 Å)
Cite:Structural insights into the targeting specificity of ubiquitin ligase for S. cerevisiae isocitrate lyase but not C. albicans isocitrate lyase.
J.Struct.Biol., 213, 2021
7EBE
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BU of 7ebe by Molmil
Crystal structure of Isocitrate lyase-1 from Candida albicans
Descriptor: FORMIC ACID, Isocitrate lyase, MAGNESIUM ION
Authors:Hiragi, K, Nishio, K, Moriyama, S, Hamaguchi, T, Mizoguchi, A, Yonekura, K, Tani, K, Mizushima, T.
Deposit date:2021-03-09
Release date:2021-06-23
Last modified:2023-11-29
Method:X-RAY DIFFRACTION (2.69 Å)
Cite:Structural insights into the targeting specificity of ubiquitin ligase for S. cerevisiae isocitrate lyase but not C. albicans isocitrate lyase.
J.Struct.Biol., 213, 2021
1JRQ
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BU of 1jrq by Molmil
X-ray Structure Analysis of the Role of the Conserved Tyrosine-369 in Active Site of E. coli Amine Oxidase
Descriptor: CALCIUM ION, COPPER (II) ION, Copper amine oxidase
Authors:Murray, J.M, Kurtis, C.R, Tambarajah, W, Saysell, C.G, Wilmot, C.M, Parsons, M.R, Phillips, S.E.V, Knowles, P.F, McPherson, M.J.
Deposit date:2001-08-14
Release date:2001-11-21
Last modified:2023-08-16
Method:X-RAY DIFFRACTION (2.15 Å)
Cite:Conserved tyrosine-369 in the active site of Escherichia coli copper amine oxidase is not essential.
Biochemistry, 40, 2001
8TMZ
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BU of 8tmz by Molmil
Crystal structure of MERS-CoV spike stem helix peptide in complex with neutralizing antibody CHM-27
Descriptor: 1,2-ETHANEDIOL, Neutralizing antibody CHM-27 Heavy Chain, Neutralizing antibody CHM-27 Light Chain, ...
Authors:Yuan, M, Wilson, I.A.
Deposit date:2023-07-31
Release date:2024-07-31
Last modified:2024-10-16
Method:X-RAY DIFFRACTION (1.8 Å)
Cite:Broad Neutralizing Antibodies Against Coronaviruses.
Not published
8TMY
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BU of 8tmy by Molmil
Crystal structure of SARS-CoV-2 spike stem helix peptide in complex with neutralizing antibody CHM-16
Descriptor: CITRATE ANION, Neutralizing antibody CHM-16 Heavy Chain, Neutralizing antibody CHM-16 Light Chain, ...
Authors:Feng, Z, Wilson, I.A.
Deposit date:2023-07-31
Release date:2024-07-31
Last modified:2024-10-16
Method:X-RAY DIFFRACTION (3.07 Å)
Cite:Broad Neutralizing Antibodies Against Coronaviruses.
Not published
2F6L
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BU of 2f6l by Molmil
X-ray structure of Chorismate Mutase from Mycobacterium Tuberculosis
Descriptor: Chorismate mutase
Authors:Kim, S.K, Howard, A.J, Gilliland, G.L, Reddy, P.T, Ladner, J.E.
Deposit date:2005-11-29
Release date:2005-12-13
Last modified:2024-10-16
Method:X-RAY DIFFRACTION (1.7 Å)
Cite:Biochemical and structural characterization of the secreted chorismate mutase (Rv1885c) from Mycobacterium tuberculosis H37Rv: an *AroQ enzyme not regulated by the aromatic amino acids.
J.Bacteriol., 188, 2006
1EBA
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BU of 1eba by Molmil
COMPLEX BETWEEN THE EXTRACELLULAR DOMAIN OF ERYTHROPOIETIN (EPO) RECEPTOR [EBP] AND AN INACTIVE PEPTIDE [EMP33] CONTAINS 3,5-DIBROMOTYROSINE IN POSITION 4 (DENOTED DBY)
Descriptor: PROTEIN (EPO MIMETICS PEPTIDE 33), PROTEIN (ERYTHROPOIETIN RECEPTOR)
Authors:Livnah, O, Stura, E.A, Wilson, I.A.
Deposit date:1998-10-02
Release date:1998-11-11
Last modified:2023-08-09
Method:X-RAY DIFFRACTION (2.7 Å)
Cite:An antagonist peptide-EPO receptor complex suggests that receptor dimerization is not sufficient for activation.
Nat.Struct.Biol., 5, 1998
4ARN
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BU of 4arn by Molmil
Crystal structure of the N-terminal domain of Drosophila Toll receptor
Descriptor: 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, MALONATE ION, ...
Authors:Gangloff, M, Gay, N.J.
Deposit date:2012-04-25
Release date:2013-01-23
Last modified:2023-12-20
Method:X-RAY DIFFRACTION (2.41 Å)
Cite:Functional Insights from the Crystal Structure of the N-Terminal Domain of the Prototypical Toll Receptor.
Structure, 21, 2013
2V5A
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BU of 2v5a by Molmil
CRYSTAL STRUCTURE OF BIOTIN CARBOXYLASE FROM E.COLI IN COMPLEX WITH POTENT INHIBITOR 3
Descriptor: 7-(2,5-dihydropyrrol-1-yl)-6-phenyl-pyrido[6,5-d]pyrimidin-2-amine, BIOTIN CARBOXYLASE, CHLORIDE ION
Authors:Mochalkin, I, Miller, J.R.
Deposit date:2008-10-02
Release date:2009-01-13
Last modified:2023-12-13
Method:X-RAY DIFFRACTION (2.31 Å)
Cite:A Class of Selective Antibacterials Derived from a Protein Kinase Inhibitor Pharmacophore.
Proc.Natl.Acad.Sci.USA, 106, 2009
4BFH
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BU of 4bfh by Molmil
Crystal structure of alpha-amylase inhibitor wrightide R1 (wR1) peptide from Wrightia religiosa
Descriptor: WRIGHTIDE R1
Authors:Yap, L.J, Nguyen, P.Q.T, Tam, J.P, Lescar, J.
Deposit date:2013-03-19
Release date:2013-07-10
Last modified:2024-10-16
Method:X-RAY DIFFRACTION (1.25 Å)
Cite:Discovery and Characterization of Pseudocyclic Cystine-Knot Alpha-Amylase Inhibitors with High Resistance to Heat and Proteolytic Degradation.
FEBS J., 281, 2014

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數據於2024-10-16公開中

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