3F9M

Human pancreatic glucokinase in complex with glucose and activator showing a mobile flap

Summary for 3F9M

Entry DOI	10.2210/pdb3f9m/pdb
Related	1V4S 1V4T
Descriptor	Glucokinase, alpha-D-glucopyranose, 2-AMINO-4-FLUORO-5-[(1-METHYL-1H-IMIDAZOL-2-YL)SULFANYL]-N-(1,3-THIAZOL-2-YL)BENZAMIDE, ... (4 entities in total)
Functional Keywords	glucokinase, hexokinase iv, atp-binding, diabetes mellitus, disease mutation, glycolysis, kinase, nucleotide-binding, transferase
Biological source	Homo sapiens (Human)
Total number of polymer chains	1
Total formula weight	53525.75
Authors	Petit, P.,Gluais, L.,Lagarde, A.,Vuillard, L.,Boutin, J.A.,Ferry, G. (deposition date: 2008-11-14, release date: 2008-12-02, Last modification date: 2023-11-01)
Primary citation	Petit, P.,Antoine, M.,Ferry, G.,Boutin, J.A.,Lagarde, A.,Gluais, L.,Vincentelli, R.,Vuillard, L. The active conformation of human glucokinase is not altered by allosteric activators Acta Crystallogr.,Sect.D, 67:929-935, 2011 Cited by PubMed: 22101819 DOI: 10.1107/S0907444911036729 PDB entries with the same primary citation
Experimental method	X-RAY DIFFRACTION (1.5 Å)

Structure validation