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7WGE
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BU of 7wge by Molmil
Human NLRP1 complexed with thioredoxin
Descriptor: MAGNESIUM ION, NACHT, LRR and PYD domains-containing protein 1, ...
Authors:Zhang, Z, Ohto, U, Shimizu, T.
Deposit date:2021-12-28
Release date:2023-07-05
Last modified:2023-10-18
Method:ELECTRON MICROSCOPY (3.4 Å)
Cite:Structural basis for thioredoxin-mediated suppression of NLRP1 inflammasome.
Nature, 622, 2023
5D96
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BU of 5d96 by Molmil
Oxidoreductase Fragment of Mouse QSOX1 in Complex with a FAb Fragment from an Antibody Targeting Mouse and Human QSOX1
Descriptor: Heavy chain of Fab fragment from an antibody targeting mouse and human QSOX1, Light chain of Fab fragment from an antibody targeting mouse and human QSOX1, Sulfhydryl oxidase 1
Authors:Fass, D, Grossman, I.
Deposit date:2015-08-18
Release date:2016-02-10
Last modified:2024-01-10
Method:X-RAY DIFFRACTION (2.3 Å)
Cite:Overcoming a species-specificity barrier in development of an inhibitory antibody targeting a modulator of tumor stroma.
Protein Eng.Des.Sel., 29, 2016
5D93
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BU of 5d93 by Molmil
Oxidoreductase Fragment of Mouse QSOX1 in Complex with a FAb Fragment from a Mouse QSOX1-Specific Antibody
Descriptor: Heavy Chain of Fab Fragment from a Mouse QSOX1-Specific Antibody, Light Chain of Fab Fragment from a Mouse QSOX1-Specific Antibody, Sulfhydryl oxidase 1
Authors:Grossman, I, Fass, D.
Deposit date:2015-08-18
Release date:2016-02-10
Last modified:2024-01-10
Method:X-RAY DIFFRACTION (2.201 Å)
Cite:Overcoming a species-specificity barrier in development of an inhibitory antibody targeting a modulator of tumor stroma.
Protein Eng.Des.Sel., 29, 2016
7YSI
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BU of 7ysi by Molmil
Crystal structure of thioredoxin 2
Descriptor: Thiol disulfide reductase thioredoxin, ZINC ION
Authors:Chang, Y.J, Park, H.H.
Deposit date:2022-08-12
Release date:2023-03-15
Last modified:2023-11-29
Method:X-RAY DIFFRACTION (1.202 Å)
Cite:Comparison of the structure and activity of thioredoxin 2 and thioredoxin 1 from Acinetobacter baumannii.
Iucrj, 10, 2023
4LL4
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BU of 4ll4 by Molmil
The structure of the TRX and TXNIP complex
Descriptor: Thioredoxin, Thioredoxin-interacting protein
Authors:Hwang, J, Kim, M.H.
Deposit date:2013-07-09
Release date:2014-02-05
Last modified:2023-11-08
Method:X-RAY DIFFRACTION (2.7 Å)
Cite:The structural basis for the negative regulation of thioredoxin by thioredoxin-interacting protein
Nat Commun, 5, 2014
7K58
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BU of 7k58 by Molmil
Structure of outer-arm dyneins bound to microtubule with microtubule binding state 1(MTBS-1)
Descriptor: ADENOSINE-5'-DIPHOSPHATE, ADENOSINE-5'-TRIPHOSPHATE, Dynein heavy chain, ...
Authors:Qinhui, R, Kai, Z.
Deposit date:2020-09-16
Release date:2021-09-29
Last modified:2021-10-20
Method:ELECTRON MICROSCOPY (3.5 Å)
Cite:Structures of outer-arm dynein array on microtubule doublet reveal a motor coordination mechanism.
Nat.Struct.Mol.Biol., 28, 2021
7KEK
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BU of 7kek by Molmil
Structure of the free outer-arm dynein in pre-parallel state
Descriptor: ADENOSINE-5'-DIPHOSPHATE, ADENOSINE-5'-TRIPHOSPHATE, Dynein alpha heavy chain, ...
Authors:Rao, Q, Zhang, K.
Deposit date:2020-10-11
Release date:2021-09-29
Last modified:2021-10-20
Method:ELECTRON MICROSCOPY (8 Å)
Cite:Structures of outer-arm dynein array on microtubule doublet reveal a motor coordination mechanism.
Nat.Struct.Mol.Biol., 28, 2021
4LL1
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BU of 4ll1 by Molmil
The structure of the TRX and TXNIP complex
Descriptor: Thioredoxin, Thioredoxin-interacting protein
Authors:Hwang, J, Kim, M.H.
Deposit date:2013-07-09
Release date:2014-02-05
Last modified:2024-04-03
Method:X-RAY DIFFRACTION (2 Å)
Cite:The structural basis for the negative regulation of thioredoxin by thioredoxin-interacting protein
Nat Commun, 5, 2014
6P7E
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BU of 6p7e by Molmil
Structure of T7 DNA Polymerase Bound to a Primer/Template DNA and a Peptide that Mimics the C-terminal Tail of the Primase-Helicase
Descriptor: ASP-THR-ASP-PHE peptide, DNA (25-MER), DNA (5'-D(P*GP*GP*CP*AP*GP*GP*TP*GP*GP*TP*CP*TP*TP*GP*CP*CP*GP*GP*TP*GP*A)-3'), ...
Authors:Foster, B.M, Rosenberg, D, Salvo, H, Stephens, K.L, Bintz, B.J, Hammel, M, Ellenberger, T, Gainey, M.D, Wallen, J.R.
Deposit date:2019-06-05
Release date:2020-03-04
Last modified:2023-10-11
Method:X-RAY DIFFRACTION (3.001 Å)
Cite:Combined Solution and Crystal Methods Reveal the Electrostatic Tethers That Provide a Flexible Platform for Replication Activities in the Bacteriophage T7 Replisome.
Biochemistry, 58, 2019
7SCE
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BU of 7sce by Molmil
Ternary complex of fixed-arm Trx-3ost5 (I299E) with 8mer-2 octasaccharide substrate and co-factor product PAP
Descriptor: 2-deoxy-6-O-sulfo-2-(sulfoamino)-alpha-D-glucopyranose-(1-4)-beta-D-glucopyranuronic acid-(1-4)-2-deoxy-6-O-sulfo-2-(sulfoamino)-alpha-D-glucopyranose-(1-4)-beta-D-glucopyranuronic acid-(1-4)-2-deoxy-6-O-sulfo-2-(sulfoamino)-alpha-D-glucopyranose-(1-4)-2-O-sulfo-alpha-L-idopyranuronic acid, ADENOSINE-3'-5'-DIPHOSPHATE, Thioredoxin 1,Heparan sulfate glucosamine 3-O-sulfotransferase 5
Authors:Wander, R, Kaminski, A.M, Krahn, J.M, Liu, J, Pedersen, L.C.
Deposit date:2021-09-27
Release date:2022-01-19
Last modified:2023-10-18
Method:X-RAY DIFFRACTION (2.75 Å)
Cite:Structural and Substrate Specificity Analysis of 3-O-Sulfotransferase Isoform 5 to Synthesize Heparan Sulfate
Acs Catalysis, 11, 2021
7ZSC
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BU of 7zsc by Molmil
Crystal structure of the heterodimeric human C-P4H-II with truncated alpha subunit (C-P4H-II delta281)
Descriptor: Prolyl 4-hydroxylase subunit alpha-2, Protein disulfide-isomerase, SULFATE ION
Authors:Lebedev, A, Koski, M.K, Wierenga, R.K, Murthy, A.V, Sulu, R.
Deposit date:2022-05-06
Release date:2022-11-09
Last modified:2024-01-31
Method:X-RAY DIFFRACTION (3.85 Å)
Cite:Crystal structure of the collagen prolyl 4-hydroxylase (C-P4H) catalytic domain complexed with PDI: Toward a model of the C-P4H alpha 2 beta 2 tetramer.
J.Biol.Chem., 298, 2022
7SCD
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BU of 7scd by Molmil
Ternary complex of fixed-arm Trx-3ost5 (I299E) with 8mer-1 octasaccharide substrate and co-factor product PAP
Descriptor: 2-deoxy-6-O-sulfo-2-(sulfoamino)-alpha-D-glucopyranose-(1-4)-beta-D-glucopyranuronic acid-(1-4)-2-deoxy-6-O-sulfo-2-(sulfoamino)-alpha-D-glucopyranose-(1-4)-beta-D-glucopyranuronic acid-(1-4)-2-deoxy-6-O-sulfo-2-(sulfoamino)-alpha-D-glucopyranose-(1-4)-beta-D-glucopyranuronic acid, ADENOSINE-3'-5'-DIPHOSPHATE, Thioredoxin 1,Heparan sulfate glucosamine 3-O-sulfotransferase 5
Authors:Wander, R, Kaminski, A.M, Krahn, J.M, Liu, J, Pedersen, L.C.
Deposit date:2021-09-27
Release date:2022-01-19
Last modified:2023-10-18
Method:X-RAY DIFFRACTION (2.9 Å)
Cite:Structural and Substrate Specificity Analysis of 3-O-Sulfotransferase Isoform 5 to Synthesize Heparan Sulfate
Acs Catalysis, 11, 2021
8AON
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BU of 8aon by Molmil
Oxidoreductase fragment of human QSOX1 in complex with a Fab fragment of a humanized anti-QSOX1 antibody
Descriptor: GLYCEROL, Heavy chain, Light chain, ...
Authors:Khmelnitsky, L, Fass, D.
Deposit date:2022-08-08
Release date:2023-08-02
Method:X-RAY DIFFRACTION (2.1 Å)
Cite:Reliable energy-based antibody humanization and stabilization
To Be Published
7C2B
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BU of 7c2b by Molmil
Crystal structure of ferredoxin: thioredoxin reductase and thioredoxin f2 complex
Descriptor: Ferredoxin-thioredoxin reductase catalytic chain, chloroplastic, Ferredoxin-thioredoxin reductase variable chain, ...
Authors:Kurisu, G, Juniar, L, Tanaka, H.
Deposit date:2020-05-07
Release date:2020-10-14
Last modified:2023-11-29
Method:X-RAY DIFFRACTION (1.7949 Å)
Cite:Structural basis for thioredoxin isoform-based fine-tuning of ferredoxin-thioredoxin reductase activity.
Protein Sci., 29, 2020
7C3F
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BU of 7c3f by Molmil
Crystal structure of ferredoxin: thioredoxin reductase and thioredoxin m2 complex
Descriptor: Ferredoxin-thioredoxin reductase catalytic chain, chloroplastic, Ferredoxin-thioredoxin reductase variable chain, ...
Authors:Kurisu, G, Juniar, L, Tanaka, H.
Deposit date:2020-05-12
Release date:2020-10-14
Last modified:2023-11-29
Method:X-RAY DIFFRACTION (2.3986 Å)
Cite:Structural basis for thioredoxin isoform-based fine-tuning of ferredoxin-thioredoxin reductase activity.
Protein Sci., 29, 2020
3HD5
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BU of 3hd5 by Molmil
Crystal structure of a thiol:disulfide interchange protein dsbA from Bordetella parapertussis
Descriptor: Thiol:disulfide interchange protein dsbA
Authors:Palani, K, Burley, S.K, Swaminathan, S, New York SGX Research Center for Structural Genomics (NYSGXRC)
Deposit date:2009-05-06
Release date:2009-05-19
Last modified:2021-02-10
Method:X-RAY DIFFRACTION (2.35 Å)
Cite:Crystal structure of a thiol:disulfide interchange protein dsbA from Bordetella parapertussis
To be Published
5AYL
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BU of 5ayl by Molmil
Crystal structure of ERdj5 form II
Descriptor: 3-PYRIDINIUM-1-YLPROPANE-1-SULFONATE, DnaJ homolog subfamily C member 10
Authors:Watanabe, S, Maegawa, K, Inaba, K.
Deposit date:2015-08-22
Release date:2017-02-15
Last modified:2023-11-08
Method:X-RAY DIFFRACTION (2.4 Å)
Cite:Highly dynamic nature of ERdj5 is essential for enhancement of the ER associated degradation
To Be Published
6Y4Z
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BU of 6y4z by Molmil
The crystal structure of human MACROD2 in space group P43212
Descriptor: L(+)-TARTARIC ACID, Thioredoxin 1,ADP-ribose glycohydrolase MACROD2
Authors:Wazir, S, Maksimainen, M.M, Lehtio, L.
Deposit date:2020-02-24
Release date:2020-09-30
Last modified:2024-01-24
Method:X-RAY DIFFRACTION (1.9 Å)
Cite:Multiple crystal forms of human MacroD2.
Acta Crystallogr.,Sect.F, 76, 2020
6Y4Y
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BU of 6y4y by Molmil
The crystal structure of human MACROD2 in space group P41212
Descriptor: L(+)-TARTARIC ACID, Thioredoxin 1,ADP-ribose glycohydrolase MACROD2
Authors:Wazir, S, Maksimainen, M.M, Lehtio, L.
Deposit date:2020-02-24
Release date:2020-09-30
Last modified:2024-01-24
Method:X-RAY DIFFRACTION (1.75 Å)
Cite:Multiple crystal forms of human MacroD2.
Acta Crystallogr.,Sect.F, 76, 2020
8B6F
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BU of 8b6f by Molmil
Cryo-EM structure of NADH:ubiquinone oxidoreductase (complex-I) from respiratory supercomplex of Tetrahymena thermophila
Descriptor: 1,2-DIACYL-SN-GLYCERO-3-PHOSPHOCHOLINE, 1,2-Distearoyl-sn-glycerophosphoethanolamine, 2 iron, ...
Authors:Muhleip, A, Kock Flygaard, R, Amunts, A.
Deposit date:2022-09-27
Release date:2023-03-29
Last modified:2023-04-12
Method:ELECTRON MICROSCOPY (2.8 Å)
Cite:Structural basis of mitochondrial membrane bending by the I-II-III 2 -IV 2 supercomplex.
Nature, 615, 2023
6YEV
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BU of 6yev by Molmil
Crystal structure of MsrA C206 and Trx C35S complex from Escherichia coli
Descriptor: Peptide methionine sulfoxide reductase MsrA, SODIUM ION, Thioredoxin 1
Authors:Napolitano, S, Zyla, D, Glockshuber, R.
Deposit date:2020-03-25
Release date:2021-04-07
Last modified:2024-01-24
Method:X-RAY DIFFRACTION (2.94 Å)
Cite:Structure of a complex between the single-cysteine mutant MsrA C206 and Trx C35S from Escherichia coli
To Be Published
8BWY
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BU of 8bwy by Molmil
In situ outer dynein arm from Chlamydomonas reinhardtii in a pre-power stroke state
Descriptor: ADENOSINE-5'-DIPHOSPHATE, ADENOSINE-5'-TRIPHOSPHATE, Calmodulin, ...
Authors:Zimmermann, N.E.L, Noga, A, Obbineni, J.M, Ishikawa, T.
Deposit date:2022-12-07
Release date:2023-05-10
Last modified:2023-06-28
Method:ELECTRON MICROSCOPY (38 Å)
Cite:ATP-induced conformational change of axonemal outer dynein arms revealed by cryo-electron tomography.
Embo J., 42, 2023
5AYK
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BU of 5ayk by Molmil
Crystal structure of ERdj5 form I
Descriptor: 3-PYRIDINIUM-1-YLPROPANE-1-SULFONATE, CHLORIDE ION, DnaJ homolog subfamily C member 10
Authors:Watanabe, S, Maegawa, K, Inaba, K.
Deposit date:2015-08-22
Release date:2017-02-15
Last modified:2023-11-08
Method:X-RAY DIFFRACTION (2.25 Å)
Cite:Highly dynamic nature of ERdj5 is essential for enhancement of the ER associated degradation
To Be Published
1OAZ
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BU of 1oaz by Molmil
IgE Fv SPE7 complexed with a recombinant thioredoxin
Descriptor: IMMUNOGLOBULIN E, THIOREDOXIN 1
Authors:James, L.C, Roversi, P, Tawfik, D.
Deposit date:2003-01-21
Release date:2004-01-15
Last modified:2013-10-30
Method:X-RAY DIFFRACTION (2.78 Å)
Cite:Antibody Multispecificity Mediated by Conformational Diversity
Science, 299, 2003
5CRW
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BU of 5crw by Molmil
Crystal structure of the b'-a' domain of oxidized protein disulfide isomerase complexed with alpha-synuclein peptide (31-41)
Descriptor: Peptide from Alpha-synuclein, Protein disulfide-isomerase
Authors:Yagi-Utsumi, M, Satoh, T, Kato, K.
Deposit date:2015-07-23
Release date:2015-09-09
Last modified:2023-11-08
Method:X-RAY DIFFRACTION (1.6 Å)
Cite:Structural basis of redox-dependent substrate binding of protein disulfide isomerase.
Sci Rep, 5, 2015

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數據於2024-07-10公開中

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