6P7E

Structure of T7 DNA Polymerase Bound to a Primer/Template DNA and a Peptide that Mimics the C-terminal Tail of the Primase-Helicase

Summary for 6P7E

• Entry DOI: 10.2210/pdb6p7e/pdb
• Descriptor: DNA-directed DNA polymerase, TrxA, DNA (5'-D(P*GP*GP*CP*AP*GP*GP*TP*GP*GP*TP*CP*TP*TP*GP*CP*CP*GP*GP*TP*GP*A)-3'), ... (9 entities in total)
• Functional Keywords: dna replication, dna polymerase, dna binding protein, transferase-dna binding protein-dna complex, transferase/dna binding protein/dna
• Biological source: Enterobacteria phage T7 (Bacteriophage T7); More
• Total number of polymer chains: 19
• Total formula weight: 427892.20

Authors

Foster, B.M.,Rosenberg, D.,Salvo, H.,Stephens, K.L.,Bintz, B.J.,Hammel, M.,Ellenberger, T.,Gainey, M.D.,Wallen, J.R. (deposition date: 2019-06-05, release date: 2020-03-04, Last modification date: 2023-10-11)

• Primary citation: Foster, B.M.,Rosenberg, D.,Salvo, H.,Stephens, K.L.,Bintz, B.J.,Hammel, M.,Ellenberger, T.,Gainey, M.D.,Wallen, J.R.; Combined Solution and Crystal Methods Reveal the Electrostatic Tethers That Provide a Flexible Platform for Replication Activities in the Bacteriophage T7 Replisome.; Biochemistry, 58:4466-4479, 2019; PubMed: 31659895; DOI: 10.1021/acs.biochem.9b00525

Experimental method

X-RAY DIFFRACTION (3.001 Å)