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6DBT	Cryo-EM structure of RAG in complex with 12-RSS and 23-RSS substrate DNAs Descriptor: CALCIUM ION, Forward strand of 12-RSS substrate DNA, Forward strand of 23-RSS substrate DNA, ... Authors: Wu, H, Liao, M, Ru, H, Mi, W. Deposit date: 2018-05-03 Release date: 2018-08-01 Last modified: 2024-03-13 Method: ELECTRON MICROSCOPY (4.3 Å) Cite: DNA melting initiates the RAG catalytic pathway. Nat. Struct. Mol. Biol., 25, 2018
6DBU	Cryo-EM structure of RAG in complex with 12-RSS and 23-RSS substrate DNAs Descriptor: CALCIUM ION, Forward strand RSS substrate DNA, Recombination activating gene 1 - MBP chimera, ... Authors: Wu, H, Liao, M, Ru, H, Mi, W. Deposit date: 2018-05-03 Release date: 2018-08-01 Last modified: 2024-03-13 Method: ELECTRON MICROSCOPY (3.9 Å) Cite: DNA melting initiates the RAG catalytic pathway. Nat. Struct. Mol. Biol., 25, 2018
6DBV	Cryo-EM structure of RAG in complex with 12-RSS and 23-RSS substrate DNAs Descriptor: CALCIUM ION, Forward strand of 12-RSS substrate DNA, Forward strand of 23-RSS substrate DNA, ... Authors: Wu, H, Liao, M, Ru, H, Mi, W. Deposit date: 2018-05-03 Release date: 2018-08-01 Last modified: 2024-11-06 Method: ELECTRON MICROSCOPY (4.29 Å) Cite: DNA melting initiates the RAG catalytic pathway. Nat. Struct. Mol. Biol., 25, 2018
6DBO	Cryo-EM structure of RAG in complex with 12-RSS and 23-RSS substrate DNAs Descriptor: CALCIUM ION, Forward strand of substrate RSS DNA, Recombination activating gene 1 - MBP chimera, ... Authors: Wu, H, Liao, M, Ru, H, Mi, W. Deposit date: 2018-05-03 Release date: 2018-08-01 Last modified: 2024-03-13 Method: ELECTRON MICROSCOPY (4.4 Å) Cite: DNA melting initiates the RAG catalytic pathway. Nat. Struct. Mol. Biol., 25, 2018
6DBW	Cryo-EM structure of RAG in complex with 12-RSS substrate DNA Descriptor: CALCIUM ION, Forward strand of 12-RSS substrate DNA, Recombination activating gene 1 - MBP chimera, ... Authors: Wu, H, Liao, M, Ru, H, Mi, W. Deposit date: 2018-05-03 Release date: 2018-08-01 Last modified: 2024-03-13 Method: ELECTRON MICROSCOPY (4.7 Å) Cite: DNA melting initiates the RAG catalytic pathway. Nat. Struct. Mol. Biol., 25, 2018
6DBX	Cryo-EM structure of RAG in complex with 12-RSS substrate DNA Descriptor: CALCIUM ION, Forward strand of 12-RSS substrate DNA, Recombination activating gene 1 - MBP chimera, ... Authors: Wu, H, Liao, M, Ru, H, Mi, W. Deposit date: 2018-05-03 Release date: 2018-08-01 Last modified: 2024-03-13 Method: ELECTRON MICROSCOPY (4.2 Å) Cite: DNA melting initiates the RAG catalytic pathway. Nat. Struct. Mol. Biol., 25, 2018
7UPN	Maedi visna virus Vif in complex with CypA and E3 ubiquitin ligase Descriptor: Elongin-B, Elongin-C, Peptidyl-prolyl cis-trans isomerase A, ... Authors: Hu, Y, Xiong, Y. Deposit date: 2022-04-16 Release date: 2023-01-25 Last modified: 2024-06-12 Method: ELECTRON MICROSCOPY (3.5 Å) Cite: Structural basis for recruitment of host CypA and E3 ubiquitin ligase by maedi-visna virus Vif. Sci Adv, 9, 2023
6CVP	Human Aprataxin (Aptx) R199H bound to RNA-DNA, AMP and Zn product complex Descriptor: ADENOSINE MONOPHOSPHATE, Aprataxin, DNA (5'-D(*GP*AP*AP*TP*CP*AP*TP*AP*AP*C)-3'), ... Authors: Schellenberg, M.J, Williams, R.S, Tumbale, P.S. Deposit date: 2018-03-28 Release date: 2018-07-04 Last modified: 2023-10-04 Method: X-RAY DIFFRACTION (1.999 Å) Cite: Mechanism of APTX nicked DNA sensing and pleiotropic inactivation in neurodegenerative disease. EMBO J., 37, 2018
6CVS	Human Aprataxin (Aptx) L248M bound to DNA, AMP and Zn product Descriptor: ADENOSINE MONOPHOSPHATE, Aprataxin, BETA-MERCAPTOETHANOL, ... Authors: Schellenberg, M.J, Tumbale, P.S, Williams, R.S. Deposit date: 2018-03-28 Release date: 2018-07-04 Last modified: 2023-10-04 Method: X-RAY DIFFRACTION (2.11 Å) Cite: Mechanism of APTX nicked DNA sensing and pleiotropic inactivation in neurodegenerative disease. EMBO J., 37, 2018
6CVR	Human Aprataxin (Aptx) S242N bound to RNA-DNA, AMP and Zn product complex Descriptor: ADENOSINE MONOPHOSPHATE, Aprataxin, DNA (5'-D(*GP*AP*AP*TP*CP*AP*TP*AP*AP*C)-3'), ... Authors: Schellenberg, M.J, Tumbale, P.S, Williams, R.S. Deposit date: 2018-03-28 Release date: 2018-07-04 Last modified: 2023-10-04 Method: X-RAY DIFFRACTION (1.88 Å) Cite: Mechanism of APTX nicked DNA sensing and pleiotropic inactivation in neurodegenerative disease. EMBO J., 37, 2018
6CVQ	Human Aprataxin (Aptx) H201Q bound to RNA-DNA, AMP and Zn product complex Descriptor: ADENOSINE MONOPHOSPHATE, Aprataxin, BETA-MERCAPTOETHANOL, ... Authors: Schellenberg, M.J, Tumbale, P.S, Williams, R.S. Deposit date: 2018-03-28 Release date: 2018-07-04 Last modified: 2023-10-04 Method: X-RAY DIFFRACTION (1.65 Å) Cite: Mechanism of APTX nicked DNA sensing and pleiotropic inactivation in neurodegenerative disease. EMBO J., 37, 2018
6CVO	Human Aprataxin (Aptx) bound to nicked RNA-DNA, AMP and Zn product complex Descriptor: ADENOSINE MONOPHOSPHATE, Aprataxin, BETA-MERCAPTOETHANOL, ... Authors: Schellenberg, M.J, Tumbale, P.P, Williams, R.S. Deposit date: 2018-03-28 Release date: 2018-08-29 Last modified: 2023-10-04 Method: X-RAY DIFFRACTION (2.4 Å) Cite: Mechanism of APTX nicked DNA sensing and pleiotropic inactivation in neurodegenerative disease. EMBO J., 37, 2018
6CVT	Human Aprataxin (Aptx) V263G bound to RNA-DNA, AMP and Zn product complex Descriptor: ADENOSINE MONOPHOSPHATE, Aprataxin, DNA (5'-D(*GP*AP*AP*TP*CP*AP*TP*AP*AP*C)-3'), ... Authors: Schellenberg, M.J, Tumbale, P.S, Williams, R.S. Deposit date: 2018-03-28 Release date: 2018-07-04 Last modified: 2023-10-04 Method: X-RAY DIFFRACTION (2.941 Å) Cite: Mechanism of APTX nicked DNA sensing and pleiotropic inactivation in neurodegenerative disease. EMBO J., 37, 2018
3U7F	Crystal structure of mPNKP catalytic fragment (D170A) bound to single-stranded DNA (TCCTCp) Descriptor: Bifunctional polynucleotide phosphatase/kinase, DNA, GLYCEROL, ... Authors: Coquelle, N, Havali, Z, Bernstein, N, Green, R, Glover, J.N.M. Deposit date: 2011-10-13 Release date: 2011-12-14 Last modified: 2024-11-06 Method: X-RAY DIFFRACTION (1.8 Å) Cite: Structural basis for the phosphatase activity of polynucleotide kinase/phosphatase on single- and double-stranded DNA substrates. Proc.Natl.Acad.Sci.USA, 108, 2011
3U7G	Crystal structure of mPNKP catalytic fragment (D170A) bound to single-stranded DNA (TCCTAp) Descriptor: Bifunctional polynucleotide phosphatase/kinase, DNA, GLYCEROL, ... Authors: Coquelle, N, Havali, Z, Bernstein, N, Green, R, Glover, J.N.M. Deposit date: 2011-10-13 Release date: 2011-12-14 Last modified: 2024-11-06 Method: X-RAY DIFFRACTION (2.1 Å) Cite: Structural basis for the phosphatase activity of polynucleotide kinase/phosphatase on single- and double-stranded DNA substrates. Proc.Natl.Acad.Sci.USA, 108, 2011
3U7H	Crystal structure of mPNKP catalytic fragment (D170A) bound to single-stranded DNA (TCCTTp) Descriptor: Bifunctional polynucleotide phosphatase/kinase, DNA, GLYCEROL, ... Authors: Coquelle, N, Havali, Z, Bernstein, N, Green, R, Glover, J.N.M. Deposit date: 2011-10-13 Release date: 2011-12-14 Last modified: 2024-11-06 Method: X-RAY DIFFRACTION (2 Å) Cite: Structural basis for the phosphatase activity of polynucleotide kinase/phosphatase on single- and double-stranded DNA substrates. Proc.Natl.Acad.Sci.USA, 108, 2011
4CI1	Structure of the DDB1-CRBN E3 ubiquitin ligase bound to thalidomide Descriptor: DNA DAMAGE-BINDING PROTEIN 1, PROTEIN CEREBLON, S-Thalidomide, ... Authors: Fischer, E.S, Boehm, K, Thoma, N.H. Deposit date: 2013-12-05 Release date: 2014-07-16 Last modified: 2024-10-16 Method: X-RAY DIFFRACTION (2.98 Å) Cite: Structure of the Ddb1-Crbn E3 Ubiquitin Ligase in Complex with Thalidomide. Nature, 512, 2014
4M6F	Dimer of the G-Segment Invertase bound to a DNA substrate Descriptor: DNA-invertase, gix site analog Authors: Ritacco, C.J, Wang, J, Steitz, T.A. Deposit date: 2013-08-09 Release date: 2014-03-12 Last modified: 2024-02-28 Method: X-RAY DIFFRACTION (4.99 Å) Cite: Exploiting large non-isomorphous differences for phase determination of a G-segment invertase-DNA complex. Acta Crystallogr.,Sect.D, 70, 2014
4WHV	E3 ubiquitin-protein ligase RNF8 in complex with Ubiquitin-conjugating enzyme E2 N and Polyubiquitin-B Descriptor: E3 ubiquitin-protein ligase RNF8, Polyubiquitin-B, Ubiquitin-conjugating enzyme E2 N, ... Authors: Hodge, C.D, Edwards, R.A, Glover, J.N.M. Deposit date: 2014-09-23 Release date: 2015-09-30 Last modified: 2023-09-27 Method: X-RAY DIFFRACTION (8.3 Å) Cite: RNF8 E3 Ubiquitin Ligase Stimulates Ubc13 E2 Conjugating Activity That Is Essential for DNA Double Strand Break Signaling and BRCA1 Tumor Suppressor Recruitment. J.Biol.Chem., 291, 2016
7LT3	NHEJ Long-range synaptic complex Descriptor: ADENOSINE-5'-DIPHOSPHATE, DNA (30-MER), DNA (31-MER), ... Authors: He, Y, Chen, S. Deposit date: 2021-02-18 Release date: 2021-04-14 Last modified: 2024-03-06 Method: ELECTRON MICROSCOPY (4.6 Å) Cite: Structural basis of long-range to short-range synaptic transition in NHEJ. Nature, 593, 2021
7KZV	Structure of the human fanconi anaemia Core-UBE2T-ID-DNA complex in closed state Descriptor: DNA (29-MER), E3 ubiquitin-protein ligase FANCL, Fanconi anemia core complex-associated protein 100, ... Authors: Wang, S.L, Pavletich, N.P. Deposit date: 2020-12-10 Release date: 2021-03-10 Last modified: 2021-03-24 Method: ELECTRON MICROSCOPY (4.2 Å) Cite: Structure of the FA core ubiquitin ligase closing the ID clamp on DNA. Nat.Struct.Mol.Biol., 28, 2021
7KZT	Structure of the human fanconi anaemia Core-UBE2T-ID-DNA complex in intermediate state Descriptor: DNA (22-MER), E3 ubiquitin-protein ligase FANCL, Fanconi anemia core complex-associated protein 100, ... Authors: Wang, S.L, Pavletich, N.P. Deposit date: 2020-12-10 Release date: 2021-03-10 Last modified: 2024-10-23 Method: ELECTRON MICROSCOPY (4.2 Å) Cite: Structure of the FA core ubiquitin ligase closing the ID clamp on DNA. Nat.Struct.Mol.Biol., 28, 2021
7KZS	Structure of the human fanconi anaemia Core-UBE2T-ID-DNA complex in open state Descriptor: DNA (25-MER), E3 ubiquitin-protein ligase FANCL, Fanconi anemia core complex-associated protein 100, ... Authors: Wang, S.L, Pavletich, N.P. Deposit date: 2020-12-10 Release date: 2021-03-10 Last modified: 2024-10-16 Method: ELECTRON MICROSCOPY (4.2 Å) Cite: Structure of the FA core ubiquitin ligase closing the ID clamp on DNA. Nat.Struct.Mol.Biol., 28, 2021
2ZO2	Mouse NP95 SRA domain non-specific DNA complex Descriptor: DNA (5'-D(*DAP*DAP*DCP*DTP*DGP*DCP*DGP*DCP*DAP*DGP*DTP*DT)-3'), E3 ubiquitin-protein ligase UHRF1, PHOSPHATE ION Authors: Hashimoto, H, Horton, J.R, Cheng, X. Deposit date: 2008-05-05 Release date: 2008-09-09 Last modified: 2023-11-01 Method: X-RAY DIFFRACTION (3.09 Å) Cite: The SRA domain of UHRF1 flips 5-methylcytosine out of the DNA helix Nature, 455, 2008
2ZO0	mouse NP95 SRA domain DNA specific complex 1 Descriptor: DNA (5'-D(*DGP*DTP*DCP*DAP*DGP*(5CM)P*DGP*DCP*DAP*DAP*DTP*DGP*DG)-3'), DNA (5'-D(*DTP*DCP*DCP*DAP*DTP*DGP*DCP*DGP*DCP*DTP*DGP*DAP*DC)-3'), E3 ubiquitin-protein ligase UHRF1 Authors: Hashimoto, H, Horton, J.R, Cheng, X. Deposit date: 2008-05-05 Release date: 2008-09-09 Last modified: 2023-11-01 Method: X-RAY DIFFRACTION (2.19 Å) Cite: The SRA domain of UHRF1 flips 5-methylcytosine out of the DNA helix Nature, 455, 2008

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