7ZBZ
 
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7Z8R
 | | CAND1-CUL1-RBX1 | | Descriptor: | Cullin-1, Cullin-associated NEDD8-dissociated protein 1, E3 ubiquitin-protein ligase RBX1, ... | | Authors: | Baek, K, Schulman, B.A. | | Deposit date: | 2022-03-18 | | Release date: | 2023-04-19 | | Last modified: | 2024-07-24 | | Method: | ELECTRON MICROSCOPY (2.7 Å) | | Cite: | Systemwide disassembly and assembly of SCF ubiquitin ligase complexes.
Cell, 186, 2023
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7Z8T
 | | CAND1-SCF-SKP2 CAND1 engaged SCF rocked | | Descriptor: | Cullin-1, Cullin-associated NEDD8-dissociated protein 1, E3 ubiquitin-protein ligase RBX1, ... | | Authors: | Baek, K, Schulman, B.A. | | Deposit date: | 2022-03-18 | | Release date: | 2023-04-19 | | Last modified: | 2024-07-24 | | Method: | ELECTRON MICROSCOPY (3 Å) | | Cite: | Systemwide disassembly and assembly of SCF ubiquitin ligase complexes.
Cell, 186, 2023
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7Z8V
 | | CAND1-SCF-SKP2 (SKP1deldel) CAND1 engaged SCF rocked | | Descriptor: | Cullin-1, Cullin-associated NEDD8-dissociated protein 1, E3 ubiquitin-protein ligase RBX1, ... | | Authors: | Baek, K, Schulman, B.A. | | Deposit date: | 2022-03-18 | | Release date: | 2023-04-19 | | Last modified: | 2024-07-24 | | Method: | ELECTRON MICROSCOPY (2.7 Å) | | Cite: | Systemwide disassembly and assembly of SCF ubiquitin ligase complexes.
Cell, 186, 2023
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4UI9
 | | Atomic structure of the human Anaphase-Promoting Complex | | Descriptor: | ANAPHASE-PROMOTING COMPLEX SUBUNIT 1, ANAPHASE-PROMOTING COMPLEX SUBUNIT 10, ANAPHASE-PROMOTING COMPLEX SUBUNIT 11, ... | | Authors: | Chang, L, Zhang, Z, Yang, J, McLaughlin, S.H, Barford, D. | | Deposit date: | 2015-03-27 | | Release date: | 2015-06-17 | | Last modified: | 2024-05-08 | | Method: | ELECTRON MICROSCOPY (3.6 Å) | | Cite: | Atomic Structure of the Apc and its Mechanism of Protein Ubiquitination
Nature, 522, 2015
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7U0F
 | | HIV-1 Rev in complex with tubulin | | Descriptor: | Protein Rev, Tubulin alpha-1A chain, Tubulin beta chain | | Authors: | Eren, E. | | Deposit date: | 2022-02-18 | | Release date: | 2023-08-23 | | Last modified: | 2023-10-18 | | Method: | ELECTRON MICROSCOPY (3.53 Å) | | Cite: | Structural basis of microtubule depolymerization by the kinesin-like activity of HIV-1 Rev.
Structure, 31, 2023
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6BSY
 | | HIV-1 Rev assembly domain (residues 1-69) | | Descriptor: | PHOSPHATE ION, Protein Rev | | Authors: | Watts, N.R, Eren, E, Zhuang, X, Wang, Y.X, Steven, A.C, Wingfield, P.T. | | Deposit date: | 2017-12-04 | | Release date: | 2018-04-11 | | Last modified: | 2023-10-04 | | Method: | X-RAY DIFFRACTION (2.25 Å) | | Cite: | A new HIV-1 Rev structure optimizes interaction with target RNA (RRE) for nuclear export.
J. Struct. Biol., 203, 2018
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3JVD
 | | Crystal structure of putative transcription regulation repressor (LACI family) FROM Corynebacterium glutamicum | | Descriptor: | GLYCEROL, SULFATE ION, Transcriptional regulators | | Authors: | Patskovsky, Y, Ramagopal, U, Toro, R, Foti, R, Freeman, J, Do, J, Sauder, J.M, Burley, S.K, Almo, S.C, New York SGX Research Center for Structural Genomics (NYSGXRC) | | Deposit date: | 2009-09-16 | | Release date: | 2009-09-22 | | Last modified: | 2024-02-21 | | Method: | X-RAY DIFFRACTION (2.3 Å) | | Cite: | Crystal structure of LACI family protein from Corynebacterium glutamicum
To be Published
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6ZVI
 | | Mbf1-ribosome complex | | Descriptor: | 18S rRNA, 40S ribosomal protein S0-A, 40S ribosomal protein S10-A, ... | | Authors: | Best, K.M, Denk, T, Cheng, J, Thoms, M, Berninghausen, O, Beckmann, R. | | Deposit date: | 2020-07-24 | | Release date: | 2020-09-09 | | Last modified: | 2024-05-01 | | Method: | ELECTRON MICROSCOPY (3 Å) | | Cite: | EDF1 coordinates cellular responses to ribosome collisions.
Elife, 9, 2020
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3K4H
 | | CRYSTAL STRUCTURE OF putative transcriptional regulator LacI from Bacillus cereus subsp. cytotoxis NVH 391-98 | | Descriptor: | alpha-D-glucopyranose-(1-4)-alpha-D-glucopyranose, putative transcriptional regulator | | Authors: | Malashkevich, V.N, Toro, R, Morano, C, Sauder, J.M, Burley, S.K, Almo, S.C, New York SGX Research Center for Structural Genomics (NYSGXRC) | | Deposit date: | 2009-10-05 | | Release date: | 2009-11-10 | | Last modified: | 2021-02-10 | | Method: | X-RAY DIFFRACTION (2.8 Å) | | Cite: | CRYSTAL STRUCTURE OF putative transcriptional regulator LacI from Bacillus cereus subsp. cytotoxis NVH 391-98
To be Published
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4O7K
 | | Crystal structure of Oncogenic Suppression Activity Protein - A Plasmid Fertility Inhibition Factor | | Descriptor: | CHLORIDE ION, ISOPROPYL ALCOHOL, PHOSPHATE ION, ... | | Authors: | Maindola, P, Goyal, P, Arulandu, A. | | Deposit date: | 2013-12-25 | | Release date: | 2014-11-05 | | Last modified: | 2024-03-20 | | Method: | X-RAY DIFFRACTION (1.748 Å) | | Cite: | Multiple enzymatic activities of ParB/Srx superfamily mediate sexual conflict among conjugative plasmids
Nat Commun, 5, 2014
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6ZWR
 | | p38a bound with SR92 | | Descriptor: | 1,2-ETHANEDIOL, 5-azanyl-~{N}-[[4-[[(2~{S})-4-cyclohexyl-1-oxidanylidene-1-(pyridin-4-ylmethylamino)butan-2-yl]carbamoyl]phenyl]methyl]-1-phenyl-pyrazole-4-carboxamide, Mitogen-activated protein kinase 14 | | Authors: | Schroeder, M, Roehm, S, Knapp, S, Arrowsmith, C.H, Bountra, C, Edwards, A.M, Structural Genomics Consortium (SGC) | | Deposit date: | 2020-07-28 | | Release date: | 2020-08-12 | | Last modified: | 2024-01-31 | | Method: | X-RAY DIFFRACTION (1.9 Å) | | Cite: | Selective targeting of the alpha C and DFG-out pocket in p38 MAPK.
Eur.J.Med.Chem., 208, 2020
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7Y0Y
 | | Crystal structure of Pseudomonas aeruginosa PvrA (SeMet) | | Descriptor: | TetR family transcriptional regulator | | Authors: | Liang, H, Zhang, Q, Bartlam, M. | | Deposit date: | 2022-06-06 | | Release date: | 2023-02-08 | | Last modified: | 2023-08-02 | | Method: | X-RAY DIFFRACTION (2.09 Å) | | Cite: | Regulatory and structural mechanisms of PvrA-mediated regulation of the PQS quorum-sensing system and PHA biosynthesis in Pseudomonas aeruginosa.
Nucleic Acids Res., 51, 2023
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4OVB
 | | Crystal structure of Oncogenic Suppression Activity Protein - A Plasmid Fertility Inhibition Factor, Gold (I) Cyanide derivative | | Descriptor: | GLYCEROL, GOLD (I) CYANIDE ION, PHOSPHATE ION, ... | | Authors: | Maindola, P, Goyal, P, Arulandu, A. | | Deposit date: | 2014-02-21 | | Release date: | 2014-11-05 | | Last modified: | 2024-03-20 | | Method: | X-RAY DIFFRACTION (2.034 Å) | | Cite: | Multiple enzymatic activities of ParB/Srx superfamily mediate sexual conflict among conjugative plasmids
Nat Commun, 5, 2014
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5G1X
 | | Crystal structure of Aurora-A kinase in complex with N-Myc | | Descriptor: | ADENOSINE-5'-DIPHOSPHATE, AURORA KINASE A, MAGNESIUM ION, ... | | Authors: | Richards, M.W, Burgess, S.G, Bayliss, R. | | Deposit date: | 2016-03-31 | | Release date: | 2016-11-16 | | Last modified: | 2024-01-10 | | Method: | X-RAY DIFFRACTION (1.72 Å) | | Cite: | Structural Basis of N-Myc Binding by Aurora-A and its Destabilization by Kinase Inhibitors
Proc.Natl.Acad.Sci.USA, 113, 2016
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6TYS
 | | A potent cross-neutralizing antibody targeting the fusion glycoprotein inhibits Nipah virus and Hendra virus infection | | Descriptor: | 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, 5B3 antibody heavy chain, ... | | Authors: | Dang, H.V, Chan, Y.P, Park, Y.J, Snijder, J, Da Silva, S.C, Vu, B, Yan, L, Feng, Y.R, Rockx, B, Geisbert, T, Mire, C.E, Broder, C.B, Veesler, D, Seattle Structural Genomics Center for Infectious Disease (SSGCID) | | Deposit date: | 2019-08-09 | | Release date: | 2019-10-09 | | Last modified: | 2024-10-09 | | Method: | ELECTRON MICROSCOPY (3.5 Å) | | Cite: | An antibody against the F glycoprotein inhibits Nipah and Hendra virus infections.
Nat.Struct.Mol.Biol., 26, 2019
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4PTA
 | | Structure of MDR initiator | | Descriptor: | Replication initiator protein | | Authors: | Schumacher, M.A. | | Deposit date: | 2014-03-10 | | Release date: | 2014-06-25 | | Last modified: | 2024-02-28 | | Method: | X-RAY DIFFRACTION (2.6003 Å) | | Cite: | Mechanism of staphylococcal multiresistance plasmid replication origin assembly by the RepA protein.
Proc.Natl.Acad.Sci.USA, 111, 2014
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5LBM
 | | The asymmetric tetrameric structure of the formaldehyde sensing transcriptional repressor FrmR from Escherichia coli | | Descriptor: | FORMYL GROUP, Transcriptional repressor FrmR | | Authors: | Bisson, C, Baker, P.J, Green, J, Chivers, P.T. | | Deposit date: | 2016-06-16 | | Release date: | 2016-12-21 | | Last modified: | 2017-08-30 | | Method: | X-RAY DIFFRACTION (2.7 Å) | | Cite: | The mechanism of a formaldehyde-sensing transcriptional regulator.
Sci Rep, 6, 2016
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3HE0
 | | The Structure of a Putative Transcriptional Regulator TetR Family Protein from Vibrio parahaemolyticus. | | Descriptor: | CHLORIDE ION, GLYCEROL, SULFATE ION, ... | | Authors: | Cuff, M.E, Hendricks, R, Moy, S, Joachimiak, A, Midwest Center for Structural Genomics (MCSG) | | Deposit date: | 2009-05-07 | | Release date: | 2009-07-07 | | Last modified: | 2017-11-01 | | Method: | X-RAY DIFFRACTION (2.2 Å) | | Cite: | The Structure of a Putative Transcriptional Regulator TetR Family Protein from Vibrio parahaemolyticus.
TO BE PUBLISHED
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4PT7
 | | Structure of initiator | | Descriptor: | Replication initiator A family protein, SULFATE ION | | Authors: | Schumacher, M.A. | | Deposit date: | 2014-03-10 | | Release date: | 2014-06-25 | | Last modified: | 2024-04-03 | | Method: | X-RAY DIFFRACTION (2.35 Å) | | Cite: | Mechanism of staphylococcal multiresistance plasmid replication origin assembly by the RepA protein.
Proc.Natl.Acad.Sci.USA, 111, 2014
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1ZT9
 | | E. coli trp repressor, tetragonal crystal form | | Descriptor: | SULFATE ION, TRYPTOPHAN, Trp operon repressor | | Authors: | Lawson, C.L, Chin, A.S, Benoff, B, Yung, B.H. | | Deposit date: | 2005-05-26 | | Release date: | 2006-05-09 | | Last modified: | 2023-08-23 | | Method: | X-RAY DIFFRACTION (2 Å) | | Cite: | Two association modes for E. coli trp repressor dimer-dimer interactions
To be Published
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3KOR
 | | Crystal structure of a putative Trp repressor from Staphylococcus aureus | | Descriptor: | Possible Trp repressor | | Authors: | Lam, R, Vodsedalek, J, Lam, K, Romanov, V, Battaile, K.P, Beletskaya, I, Pai, E.F, Chirgadze, N.Y. | | Deposit date: | 2009-11-13 | | Release date: | 2010-11-17 | | Last modified: | 2017-11-01 | | Method: | X-RAY DIFFRACTION (1.6 Å) | | Cite: | Crystal structure of a putative Trp repressor from Staphylococcus aureus
To be Published
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3BU8
 | | Crystal Structure of TRF2 TRFH domain and TIN2 peptide complex | | Descriptor: | TERF1-interacting nuclear factor 2, Telomeric repeat-binding factor 2 | | Authors: | Chen, Y, Yang, Y, van Overbeek, M, Donigian, J.R, Baciu, P, de Lange, T, Lei, M. | | Deposit date: | 2008-01-02 | | Release date: | 2008-02-19 | | Last modified: | 2023-08-30 | | Method: | X-RAY DIFFRACTION (2.15 Å) | | Cite: | A shared docking motif in TRF1 and TRF2 used for differential recruitment of telomeric proteins.
Science, 319, 2008
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6L36
 | | X-ray structure of human PPARalpha ligand binding domain-GW9662-fenofibric acid co-crystals obtained by delipidation and co-crystallization | | Descriptor: | 2-[4-(4-chlorobenzene-1-carbonyl)phenoxy]-2-methylpropanoic acid, 2-chloro-5-nitro-N-phenylbenzamide, Peroxisome proliferator-activated receptor alpha | | Authors: | Kamata, S, Saito, K, Honda, A, Ishikawa, R, Oyama, T, Ishii, I. | | Deposit date: | 2019-10-09 | | Release date: | 2020-11-11 | | Last modified: | 2023-11-22 | | Method: | X-RAY DIFFRACTION (3.301 Å) | | Cite: | PPAR alpha Ligand-Binding Domain Structures with Endogenous Fatty Acids and Fibrates.
Iscience, 23, 2020
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6LB6
 | | Crystal structure of dimeric RXR-LBD complexed with partial agonist NEt-4IB and TIF2 co-activator | | Descriptor: | 6-[ethyl-[4-(2-methylpropoxy)-3-propan-2-yl-phenyl]amino]pyridine-3-carboxylic acid, Nuclear receptor coactivator 2, Retinoic acid receptor RXR-alpha | | Authors: | Imai, D, Numoto, N, Nakano, S, Kakuta, H, Ito, N. | | Deposit date: | 2019-11-13 | | Release date: | 2020-11-18 | | Last modified: | 2024-10-02 | | Method: | X-RAY DIFFRACTION (2.4 Å) | | Cite: | Structural basis for the full and partial agonist activities of retinoid X receptor alpha ligands with an iso-butoxy and an isopropyl group
Biochem.Biophys.Res.Commun., 734, 2024
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