6TMS
| Crystal structure of a de novo designed hexameric helical-bundle protein | Descriptor: | SULFATE ION, a novel designed pore protein, affinity purification tag | Authors: | Xu, C, Pei, X.Y, Luisi, B.F, Baker, D. | Deposit date: | 2019-12-05 | Release date: | 2020-04-29 | Last modified: | 2024-05-01 | Method: | X-RAY DIFFRACTION (2.7 Å) | Cite: | Computational design of transmembrane pores. Nature, 585, 2020
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6TJ1
| Crystal structure of a de novo designed hexameric helical-bundle protein | Descriptor: | De novo designed WSHC6, purification tag | Authors: | Xu, C, Pei, X.Y, Luisi, B.F, Baker, D. | Deposit date: | 2019-11-23 | Release date: | 2020-04-29 | Last modified: | 2024-05-01 | Method: | X-RAY DIFFRACTION (2.4 Å) | Cite: | Computational design of transmembrane pores. Nature, 585, 2020
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7T3N
| R184Q/E191Q mutant of rat vesicular glutamate transporter 2 (VGLUT2) | Descriptor: | (1S,3R)-1-AMINOCYCLOPENTANE-1,3-DICARBOXYLIC ACID, (2R)-2-(methoxymethyl)-4-{[(25R)-spirost-5-en-3beta-yl]oxy}butyl 4-O-alpha-D-glucopyranosyl-beta-D-glucopyranoside, Vesicular glutamate transporter 2 | Authors: | Li, F, Stroud, R.M, Edwards, R.H. | Deposit date: | 2021-12-08 | Release date: | 2022-12-14 | Method: | ELECTRON MICROSCOPY (3 Å) | Cite: | Substrate Recognition, Directional Flux, and Allostery in a Synaptic Vesicle Glutamate Transporter To Be Published
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7T3O
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6M6Z
| A de novo designed transmembrane nanopore, TMH4C4 | Descriptor: | TMH4C4 | Authors: | Lu, P, Xu, C, Reggiano, G, Xu, Q, DiMaio, F, Baker, D. | Deposit date: | 2020-03-16 | Release date: | 2020-06-24 | Last modified: | 2024-03-27 | Method: | ELECTRON MICROSCOPY (5.9 Å) | Cite: | Computational design of transmembrane pores. Nature, 585, 2020
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7YSV
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7YSJ
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6JR0
| Crystal structure of the human nucleosome phased with 12 selenium atoms | Descriptor: | CHLORIDE ION, DNA (146-MER), Histone H2A type 1-B/E, ... | Authors: | Saotome, M, Horikoshi, N, Urano, K, Kujirai, T, Yuzurihara, H, Kurumizaka, H, Kagawa, W. | Deposit date: | 2019-04-02 | Release date: | 2019-10-02 | Last modified: | 2019-10-23 | Method: | X-RAY DIFFRACTION (2.5 Å) | Cite: | Structure determination of the nucleosome core particle by selenium SAD phasing. Acta Crystallogr D Struct Biol, 75, 2019
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6JR1
| Crystal structure of the human nucleosome phased with 16 selenium atoms | Descriptor: | CHLORIDE ION, DNA (146-MER), Histone H2A type 1-B/E, ... | Authors: | Saotome, M, Horikoshi, N, Urano, K, Kujirai, T, Yuzurihara, H, Kurumizaka, H, Kagawa, W. | Deposit date: | 2019-04-02 | Release date: | 2019-10-02 | Last modified: | 2019-10-23 | Method: | X-RAY DIFFRACTION (2.4 Å) | Cite: | Structure determination of the nucleosome core particle by selenium SAD phasing. Acta Crystallogr D Struct Biol, 75, 2019
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4D1E
| THE CRYSTAL STRUCTURE OF HUMAN MUSCLE ALPHA-ACTININ-2 | Descriptor: | ALPHA-ACTININ-2 | Authors: | Pinotsis, N, Salmazo, A, Sjoeblom, B, Gkougkoulia, E, Djinovic-Carugo, K. | Deposit date: | 2014-05-01 | Release date: | 2014-12-10 | Last modified: | 2023-12-20 | Method: | X-RAY DIFFRACTION (3.5 Å) | Cite: | The Structure and Regulation of Human Muscle Alpha-Actinin Cell(Cambridge,Mass.), 159, 2014
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3G76
| Crystal structure of XIAP-BIR3 in complex with a bivalent compound | Descriptor: | 1,1'-{hexa-2,4-diyne-1,6-diylbis[oxy{(2S,3R)-2-[(N-methyl-L-alanyl)amino]-1-oxobutane-3,1-diyl}(2S)pyrrolidine-1,2-diylmethanediyl]}bis[5-(phenylsulfanyl)-1H-tetrazole], Baculoviral IAP repeat-containing protein 4, ZINC ION | Authors: | Cossu, F, Milani, M, Mastrangelo, E, Bolognesi, M. | Deposit date: | 2009-02-09 | Release date: | 2009-05-12 | Last modified: | 2023-11-01 | Method: | X-RAY DIFFRACTION (3 Å) | Cite: | Structural basis for bivalent smac-mimetics recognition in the IAP protein family J.Mol.Biol., 392, 2009
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7N3N
| CryoEM structure of human NKCC1 state Fu-I | Descriptor: | 5-(AMINOSULFONYL)-4-CHLORO-2-[(2-FURYLMETHYL)AMINO]BENZOIC ACID, Solute carrier family 12 member 2 | Authors: | Moseng, M.A. | Deposit date: | 2021-06-01 | Release date: | 2022-09-28 | Last modified: | 2023-05-31 | Method: | ELECTRON MICROSCOPY (3.33 Å) | Cite: | Inhibition mechanism of NKCC1 involves the carboxyl terminus and long-range conformational coupling. Sci Adv, 8, 2022
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5OBX
| Mycoplasma genitalium DnaK-NBD | Descriptor: | Chaperone protein DnaK, GLYCEROL, SULFATE ION, ... | Authors: | Adell, M, Calisto, B, Fita, I, Martinelli, L. | Deposit date: | 2017-06-29 | Release date: | 2018-05-09 | Last modified: | 2024-01-17 | Method: | X-RAY DIFFRACTION (1.78 Å) | Cite: | The nucleotide-bound/substrate-bound conformation of the Mycoplasma genitalium DnaK chaperone. Protein Sci., 27, 2018
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5OBW
| Mycoplasma genitalium DnaK-NBD in complex with ATP | Descriptor: | ADENOSINE-5'-DIPHOSPHATE, Chaperone protein DnaK, GLYCEROL, ... | Authors: | Adell, M, Calisto, B, Fita, I, Martinelli, L. | Deposit date: | 2017-06-29 | Release date: | 2018-05-09 | Last modified: | 2024-01-17 | Method: | X-RAY DIFFRACTION (1.4 Å) | Cite: | The nucleotide-bound/substrate-bound conformation of the Mycoplasma genitalium DnaK chaperone. Protein Sci., 27, 2018
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5OBY
| Mycoplasma genitalium DnaK-NBD in complex with AMP-PNP | Descriptor: | Chaperone protein DnaK, GLYCEROL, MAGNESIUM ION, ... | Authors: | Adell, M, Calisto, B, Fita, I, Martinelli, L. | Deposit date: | 2017-06-29 | Release date: | 2018-05-09 | Last modified: | 2024-01-17 | Method: | X-RAY DIFFRACTION (1.3 Å) | Cite: | The nucleotide-bound/substrate-bound conformation of the Mycoplasma genitalium DnaK chaperone. Protein Sci., 27, 2018
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5EZ0
| CRYSTAL STRUCTURE OF THE PTPN4 PDZ DOMAIN COMPLEXED WITH THE PDZ BINDING MOTIF OF THE MITOGEN ACTIVATED PROTEIN KINASE P38GAMMA. | Descriptor: | Mitogen-activated protein kinase 12, SULFATE ION, Tyrosine-protein phosphatase non-receptor type 4 | Authors: | Maisonneuve, P, Vaney, M.C, Caillet-Saguy, C, Lafon, M, Delepierre, M, Cordier, F, Wolff, N. | Deposit date: | 2015-11-26 | Release date: | 2016-06-08 | Last modified: | 2024-01-10 | Method: | X-RAY DIFFRACTION (2.35 Å) | Cite: | Molecular Basis of the Interaction of the Human Protein Tyrosine Phosphatase Non-receptor Type 4 (PTPN4) with the Mitogen-activated Protein Kinase p38 gamma. J.Biol.Chem., 291, 2016
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2VAF
| Crystal structure of Human Cardiac Calsequestrin | Descriptor: | CALSEQUESTRIN-2 | Authors: | Kim, E, Youn, B, Kemper, L, Campbell, C, Milting, H, Varsanyi, M, Kang, C. | Deposit date: | 2007-08-31 | Release date: | 2007-09-11 | Last modified: | 2023-12-13 | Method: | X-RAY DIFFRACTION (3.8 Å) | Cite: | Characterization of Human Cardiac Calsequestrin and its Deleterious Mutants. J.Mol.Biol., 373, 2007
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1QPF
| FK506 BINDING PROTEIN (12 KDA, HUMAN) COMPLEX WITH L-709,858 | Descriptor: | C32-O-(1-ETHYL-INDOL-5-YL)ASCOMYCIN, PROTEIN (FK506-BINDING PROTEIN), heptyl beta-D-glucopyranoside | Authors: | Becker, J.W, Rotonda, J. | Deposit date: | 1999-05-24 | Release date: | 1999-08-16 | Last modified: | 2023-08-16 | Method: | X-RAY DIFFRACTION (2.5 Å) | Cite: | 32-Indolyl ether derivatives of ascomycin: three-dimensional structures of complexes with FK506-binding protein. J.Med.Chem., 42, 1999
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1QPL
| FK506 BINDING PROTEIN (12 KDA, HUMAN) COMPLEX WITH L-707,587 | Descriptor: | C32-O-(1-METHYL-INDOL-5-YL) 18-HYDROXY-ASCOMYCIN, PROTEIN (FK506-BINDING PROTEIN) | Authors: | Becker, J.W, Rotonda, J. | Deposit date: | 1999-05-25 | Release date: | 1999-08-16 | Last modified: | 2023-08-16 | Method: | X-RAY DIFFRACTION (2.9 Å) | Cite: | 32-Indolyl ether derivatives of ascomycin: three-dimensional structures of complexes with FK506-binding protein. J.Med.Chem., 42, 1999
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4W8L
| Structure of GH10 from Paenibacillus barcinonensis | Descriptor: | CALCIUM ION, Endo-1,4-beta-xylanase C, GLYCEROL | Authors: | Sainz-Polo, M.A, Sanz-Aparicio, J. | Deposit date: | 2014-08-25 | Release date: | 2015-06-03 | Last modified: | 2024-01-10 | Method: | X-RAY DIFFRACTION (1.76 Å) | Cite: | Exploring Multimodularity in Plant Cell Wall Deconstruction: STRUCTURAL AND FUNCTIONAL ANALYSIS OF Xyn10C CONTAINING THE CBM22-1-CBM22-2 TANDEM. J.Biol.Chem., 290, 2015
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4Y1H
| Crystal structure of K33 linked tri-Ubiquitin | Descriptor: | 1,2-ETHANEDIOL, Ubiquitin-40S ribosomal protein S27a | Authors: | Kristariyanto, Y.A, Abdul Rehman, S.A, Choi, S.Y, Ritorto, S, Campbell, D.G, Morrice, N.A, Toth, R, Kulathu, Y. | Deposit date: | 2015-02-07 | Release date: | 2015-03-18 | Last modified: | 2024-01-10 | Method: | X-RAY DIFFRACTION (1.4 Å) | Cite: | Assembly and structure of Lys33-linked polyubiquitin reveals distinct conformations. Biochem.J., 467, 2015
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8DTY
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8DVV
| Recombinant mouse RyR2 triple phosphomimetic mutant S2807D/S2813D/S2030D in complex with FKBP12.6 and nanodisc under open-state conditions | Descriptor: | CALCIUM ION, Peptidyl-prolyl cis-trans isomerase FKBP1B, Ryanodine receptor 2, ... | Authors: | Iyer, K.A, Hu, Y, Murayama, T, Samso, M. | Deposit date: | 2022-07-29 | Release date: | 2024-01-31 | Method: | ELECTRON MICROSCOPY (3.68 Å) | Cite: | Recombinant mouse RyR2 triple phosphomimetic mutant S2807D/S2813D/S2030D in complex with FKBP12.6 and nanodisc under open-state conditions To Be Published
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8DTZ
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6PNN
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