8PUG
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![BU of 8pug by Molmil](/molmil-images/mine/8pug) | Structure of the immature HTLV-1 CA lattice from full-length Gag VLPs: CA-NTD refinement | Descriptor: | Gag polyprotein | Authors: | Obr, M, Percipalle, M, Chernikova, D, Yang, H, Thader, A, Pinke, G, Porley, D, Mansky, L.M, Dick, R.A, Schur, F.K.M. | Deposit date: | 2023-07-17 | Release date: | 2023-08-23 | Method: | ELECTRON MICROSCOPY (5.9 Å) | Cite: | Unconventional stabilization of the human T-cell leukemia virus type 1 immature Gag lattice. Biorxiv, 2023
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8PUH
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![BU of 8puh by Molmil](/molmil-images/mine/8puh) | Structure of the immature HTLV-1 CA lattice from full-length Gag VLPs: CA-CTD refinement | Descriptor: | Gag polyprotein | Authors: | Obr, M, Percipalle, M, Chernikova, D, Yang, H, Thader, A, Pinke, G, Porley, D, Mansky, L.M, Dick, R.A, Schur, F.K.M. | Deposit date: | 2023-07-17 | Release date: | 2023-08-23 | Method: | ELECTRON MICROSCOPY (6.2 Å) | Cite: | Unconventional stabilization of the human T-cell leukemia virus type 1 immature Gag lattice. Biorxiv, 2023
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3TS2
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![BU of 3ts2 by Molmil](/molmil-images/mine/3ts2) | Mouse Lin28A in complex with let-7g microRNA pre-element | Descriptor: | Protein lin-28 homolog A, RNA (5'-R(*GP*GP*GP*GP*UP*CP*UP*AP*UP*GP*AP*UP*AP*CP*CP*AP*CP*CP*CP*CP*GP*GP*AP*G)-3'), ZINC ION | Authors: | Nam, Y, Sliz, P. | Deposit date: | 2011-09-11 | Release date: | 2011-11-16 | Last modified: | 2023-09-13 | Method: | X-RAY DIFFRACTION (2.01 Å) | Cite: | Molecular Basis for Interaction of let-7 MicroRNAs with Lin28. Cell(Cambridge,Mass.), 147, 2011
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3TRZ
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![BU of 3trz by Molmil](/molmil-images/mine/3trz) | Mouse Lin28A in complex with let-7d microRNA pre-element | Descriptor: | Protein lin-28 homolog A, RNA (5'-R(*GP*GP*GP*CP*AP*GP*GP*GP*AP*UP*UP*UP*UP*GP*CP*CP*CP*GP*GP*AP*G)-3'), ZINC ION | Authors: | Nam, Y, Sliz, P. | Deposit date: | 2011-09-11 | Release date: | 2011-11-16 | Last modified: | 2024-02-28 | Method: | X-RAY DIFFRACTION (2.9 Å) | Cite: | Molecular Basis for Interaction of let-7 MicroRNAs with Lin28. Cell(Cambridge,Mass.), 147, 2011
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7Z4Y
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![BU of 7z4y by Molmil](/molmil-images/mine/7z4y) | Human NEXT dimer - overall reconstruction of the core complex | Descriptor: | Exosome RNA helicase MTR4, Zinc finger CCHC domain-containing protein 8 | Authors: | Gerlach, P, Lingaraju, M, Salerno-Kochan, A, Bonneau, F, Basquin, J, Conti, E. | Deposit date: | 2022-03-06 | Release date: | 2022-06-22 | Last modified: | 2022-07-20 | Method: | ELECTRON MICROSCOPY (4.5 Å) | Cite: | Structure and regulation of the nuclear exosome targeting complex guides RNA substrates to the exosome. Mol.Cell, 82, 2022
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7Z4Z
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![BU of 7z4z by Molmil](/molmil-images/mine/7z4z) | Human NEXT dimer - focused reconstruction of the dimerization module | Descriptor: | Exosome RNA helicase MTR4, Zinc finger CCHC domain-containing protein 8 | Authors: | Gerlach, P, Lingaraju, M, Salerno-Kochan, A, Bonneau, F, Basquin, J, Conti, E. | Deposit date: | 2022-03-06 | Release date: | 2022-06-22 | Last modified: | 2022-07-20 | Method: | ELECTRON MICROSCOPY (4 Å) | Cite: | Structure and regulation of the nuclear exosome targeting complex guides RNA substrates to the exosome. Mol.Cell, 82, 2022
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7Z52
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![BU of 7z52 by Molmil](/molmil-images/mine/7z52) | Human NEXT dimer - focused reconstruction of the single MTR4 | Descriptor: | Exosome RNA helicase MTR4, PHOSPHOAMINOPHOSPHONIC ACID-ADENYLATE ESTER, RNA (5'-R(P*UP*UP*UP*UP*U)-3'), ... | Authors: | Gerlach, P, Lingaraju, M, Salerno-Kochan, A, Bonneau, F, Basquin, J, Conti, E. | Deposit date: | 2022-03-07 | Release date: | 2022-06-22 | Last modified: | 2022-07-20 | Method: | ELECTRON MICROSCOPY (3.4 Å) | Cite: | Structure and regulation of the nuclear exosome targeting complex guides RNA substrates to the exosome. Mol.Cell, 82, 2022
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6RWG
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![BU of 6rwg by Molmil](/molmil-images/mine/6rwg) | Structure of HIV-1 CAcSP1NC mutant(W41A,M42A) interacting with maturation inhibitor EP39 | Descriptor: | Gag polyprotein, ZINC ION | Authors: | Chen, X, Coric, P, Larue, V, Nonin-Lecomte, S, Bouaziz, S, Structural Genomics Consortium (SGC) | Deposit date: | 2019-06-05 | Release date: | 2020-05-20 | Last modified: | 2023-06-14 | Method: | SOLUTION NMR | Cite: | The HIV-1 maturation inhibitor, EP39, interferes with the dynamic helix-coil equilibrium of the CA-SP1 junction of Gag. Eur.J.Med.Chem., 204, 2020
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6T64
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![BU of 6t64 by Molmil](/molmil-images/mine/6t64) | A model of the EIAV CA-SP hexamer (C6) from Gag-deltaMA spheres assembled at pH6 | Descriptor: | Gag polyprotein | Authors: | Dick, R.A, Xu, C, Morado, D.R, Kravchuk, V, Ricana, C.L, Lyddon, T.D, Broad, A.M, Feathers, J.R, Johnson, M.C, Vogt, V.M, Perilla, J.R, Briggs, J.A.G, Schur, F.K.M. | Deposit date: | 2019-10-17 | Release date: | 2020-01-15 | Last modified: | 2022-03-30 | Method: | ELECTRON MICROSCOPY (3.7 Å) | Cite: | Structures of immature EIAV Gag lattices reveal a conserved role for IP6 in lentivirus assembly. Plos Pathog., 16, 2020
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6T63
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![BU of 6t63 by Molmil](/molmil-images/mine/6t63) | A model of the EIAV CA-SP hexamer (C2) from Gag-deltaMA tubes assembled at pH6 | Descriptor: | Gag polyprotein | Authors: | Dick, R.A, Xu, C, Morado, D.R, Kravchuk, V, Ricana, C.L, Lyddon, T.D, Broad, A.M, Feathers, J.R, Johnson, M.C, Vogt, V.M, Perilla, J.R, Briggs, J.A.G, Schur, F.K.M. | Deposit date: | 2019-10-17 | Release date: | 2020-01-15 | Last modified: | 2022-03-30 | Method: | ELECTRON MICROSCOPY (3.8 Å) | Cite: | Structures of immature EIAV Gag lattices reveal a conserved role for IP6 in lentivirus assembly. Plos Pathog., 16, 2020
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6T61
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![BU of 6t61 by Molmil](/molmil-images/mine/6t61) | A model of the EIAV CA-SP hexamer (C2) from Gag-deltaMA tubes assembled at pH8 | Descriptor: | Gag polyprotein | Authors: | Dick, R.A, Xu, C, Morado, D.R, Kravchuk, V, Ricana, C.L, Lyddon, T.D, Broad, A.M, Feathers, J.R, Johnson, M.C, Vogt, V.M, Perilla, J.R, Briggs, J.A.G, Schur, F.K.M. | Deposit date: | 2019-10-17 | Release date: | 2020-01-15 | Last modified: | 2022-03-30 | Method: | ELECTRON MICROSCOPY (3.7 Å) | Cite: | Structures of immature EIAV Gag lattices reveal a conserved role for IP6 in lentivirus assembly. Plos Pathog., 16, 2020
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5UDZ
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![BU of 5udz by Molmil](/molmil-images/mine/5udz) | |
5W0M
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![BU of 5w0m by Molmil](/molmil-images/mine/5w0m) | Structure of human TUT7 catalytic module (CM) in complex with U5 RNA | Descriptor: | IODIDE ION, SULFATE ION, Terminal uridylyltransferase 7, ... | Authors: | Faehnle, C.R, Walleshauser, J, Joshua-Tor, L. | Deposit date: | 2017-05-31 | Release date: | 2017-06-28 | Last modified: | 2023-10-04 | Method: | X-RAY DIFFRACTION (2.298 Å) | Cite: | Multi-domain utilization by TUT4 and TUT7 in control of let-7 biogenesis. Nat. Struct. Mol. Biol., 24, 2017
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5W0N
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![BU of 5w0n by Molmil](/molmil-images/mine/5w0n) | Structure of human TUT7 catalytic module (CM) in complex with UMPNPP and U2 RNA | Descriptor: | 5'-O-[(S)-hydroxy{[(S)-hydroxy(phosphonooxy)phosphoryl]amino}phosphoryl]uridine, IODIDE ION, MAGNESIUM ION, ... | Authors: | Faehnle, C.R, Walleshauser, J, Joshua-Tor, L. | Deposit date: | 2017-05-31 | Release date: | 2017-06-28 | Last modified: | 2023-10-04 | Method: | X-RAY DIFFRACTION (2.497 Å) | Cite: | Multi-domain utilization by TUT4 and TUT7 in control of let-7 biogenesis. Nat. Struct. Mol. Biol., 24, 2017
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5W0B
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![BU of 5w0b by Molmil](/molmil-images/mine/5w0b) | Structure of human TUT7 catalytic module (CM) | Descriptor: | IODIDE ION, SULFATE ION, Terminal uridylyltransferase 7, ... | Authors: | Faehnle, C.R, Walleshauser, J, Joshua-Tor, L. | Deposit date: | 2017-05-30 | Release date: | 2017-06-28 | Last modified: | 2024-03-13 | Method: | X-RAY DIFFRACTION (2.614 Å) | Cite: | Multi-domain utilization by TUT4 and TUT7 in control of let-7 biogenesis. Nat. Struct. Mol. Biol., 24, 2017
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5W0O
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![BU of 5w0o by Molmil](/molmil-images/mine/5w0o) | |
7C45
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![BU of 7c45 by Molmil](/molmil-images/mine/7c45) | |
7C47
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![BU of 7c47 by Molmil](/molmil-images/mine/7c47) | The crystal structure of Trypanosoma brucei RNase D : CMP complex | Descriptor: | CCHC-type domain-containing protein, CYTIDINE-5'-MONOPHOSPHATE, MANGANESE (II) ION, ... | Authors: | Gao, Y.Q, Gan, J.H. | Deposit date: | 2020-05-15 | Release date: | 2021-04-07 | Last modified: | 2024-05-29 | Method: | X-RAY DIFFRACTION (2.2 Å) | Cite: | Structural basis for guide RNA trimming by RNase D ribonuclease in Trypanosoma brucei. Nucleic Acids Res., 49, 2021
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7C42
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![BU of 7c42 by Molmil](/molmil-images/mine/7c42) | |
7C43
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![BU of 7c43 by Molmil](/molmil-images/mine/7c43) | |
7C4C
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![BU of 7c4c by Molmil](/molmil-images/mine/7c4c) | |
7C4B
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![BU of 7c4b by Molmil](/molmil-images/mine/7c4b) | The crystal structure of Trypanosoma brucei RNase D : UMP complex | Descriptor: | CCHC-type domain-containing protein, MANGANESE (II) ION, URIDINE-5'-MONOPHOSPHATE, ... | Authors: | Gao, Y.Q, Gan, J.H. | Deposit date: | 2020-05-15 | Release date: | 2021-04-07 | Last modified: | 2024-05-29 | Method: | X-RAY DIFFRACTION (2.101 Å) | Cite: | Structural basis for guide RNA trimming by RNase D ribonuclease in Trypanosoma brucei. Nucleic Acids Res., 49, 2021
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2LLI
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![BU of 2lli by Molmil](/molmil-images/mine/2lli) | Low resolution structure of RNA-binding subunit of the TRAMP complex | Descriptor: | Protein AIR2, ZINC ION | Authors: | Holub, P, Lalakova, J, Cerna, H, Sarazova, M, Pasulka, J, Hrazdilova, K, Arce, M.S, Stefl, R, Vanacova, S. | Deposit date: | 2011-11-10 | Release date: | 2012-03-21 | Last modified: | 2024-05-15 | Method: | SOLUTION NMR | Cite: | Air2p is critical for the assembly and RNA-binding of the TRAMP complex and the KOW domain of Mtr4p is crucial for exosome activation. Nucleic Acids Res., 40, 2012
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7S7B
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![BU of 7s7b by Molmil](/molmil-images/mine/7s7b) | |
7S7C
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![BU of 7s7c by Molmil](/molmil-images/mine/7s7c) | |