6RWG
Structure of HIV-1 CAcSP1NC mutant(W41A,M42A) interacting with maturation inhibitor EP39
Summary for 6RWG
Entry DOI | 10.2210/pdb6rwg/pdb |
NMR Information | BMRB: 34409 |
Descriptor | Gag polyprotein, ZINC ION (2 entities in total) |
Functional Keywords | gag, hiv-1, maturation inhibitor, ep39, structural genomics, psi-biology, structural genomics consortium, sgc, viral protein |
Biological source | Human immunodeficiency virus 1 |
Total number of polymer chains | 1 |
Total formula weight | 17576.96 |
Authors | Chen, X.,Coric, P.,Larue, V.,Nonin-Lecomte, S.,Bouaziz, S.,Structural Genomics Consortium (SGC) (deposition date: 2019-06-05, release date: 2020-05-20, Last modification date: 2024-06-19) |
Primary citation | Chen, X.,Coric, P.,Larue, V.,Turcaud, S.,Wang, X.,Nonin-Lecomte, S.,Bouaziz, S. The HIV-1 maturation inhibitor, EP39, interferes with the dynamic helix-coil equilibrium of the CA-SP1 junction of Gag. Eur.J.Med.Chem., 204:112634-112634, 2020 Cited by PubMed: 32717487DOI: 10.1016/j.ejmech.2020.112634 PDB entries with the same primary citation |
Experimental method | SOLUTION NMR |
Structure validation
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