6RWG

Structure of HIV-1 CAcSP1NC mutant(W41A,M42A) interacting with maturation inhibitor EP39

Summary for 6RWG

• Entry DOI: 10.2210/pdb6rwg/pdb
• NMR Information: BMRB: 34409
• Descriptor: Gag polyprotein, ZINC ION (2 entities in total)
• Functional Keywords: gag, hiv-1, maturation inhibitor, ep39, structural genomics, psi-biology, structural genomics consortium, sgc, viral protein
• Biological source: Human immunodeficiency virus 1
• Total number of polymer chains: 1
• Total formula weight: 17576.96

Authors

Chen, X.,Coric, P.,Larue, V.,Nonin-Lecomte, S.,Bouaziz, S.,Structural Genomics Consortium (SGC) (deposition date: 2019-06-05, release date: 2020-05-20, Last modification date: 2023-06-14)

• Primary citation: Chen, X.,Coric, P.,Larue, V.,Turcaud, S.,Wang, X.,Nonin-Lecomte, S.,Bouaziz, S.; The HIV-1 maturation inhibitor, EP39, interferes with the dynamic helix-coil equilibrium of the CA-SP1 junction of Gag.; Eur.J.Med.Chem., 204:112634-112634, 2020; PubMed: 32717487; DOI: 10.1016/j.ejmech.2020.112634

Experimental method

SOLUTION NMR