6HXM
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6HXL
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5TDE
| TEV Cleaved Human ATP Citrate Lyase Bound to Citrate | Descriptor: | ATP-citrate synthase, CITRATE ANION, DIHYDROGENPHOSPHATE ION, ... | Authors: | Hu, J, Fraser, M.E. | Deposit date: | 2016-09-19 | Release date: | 2017-08-09 | Last modified: | 2024-03-06 | Method: | X-RAY DIFFRACTION (1.7 Å) | Cite: | Binding of hydroxycitrate to human ATP-citrate lyase. Acta Crystallogr D Struct Biol, 73, 2017
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6Z2H
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5TDF
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6HXK
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5TDZ
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3MWD
| Truncated Human ATP-Citrate Lyase with Citrate Bound | Descriptor: | ATP-citrate synthase, CITRIC ACID | Authors: | Fraser, M.E, Sun, T. | Deposit date: | 2010-05-05 | Release date: | 2010-06-16 | Last modified: | 2011-07-13 | Method: | X-RAY DIFFRACTION (2.1 Å) | Cite: | Identification of the citrate-binding site of human ATP-citrate lyase using X-ray crystallography. J.Biol.Chem., 285, 2010
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5TDM
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7RIG
| Structure of ACLY-D1026A-substrates | Descriptor: | (3S)-citryl-Coenzyme A, ADENOSINE-5'-DIPHOSPHATE, ATP-citrate synthase, ... | Authors: | Wei, X, Marmorstein, R. | Deposit date: | 2021-07-19 | Release date: | 2023-05-10 | Last modified: | 2024-06-05 | Method: | ELECTRON MICROSCOPY (2.2 Å) | Cite: | Allosteric role of the citrate synthase homology domain of ATP citrate lyase. Nat Commun, 14, 2023
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3MWE
| Truncated Human ATP-Citrate Lyase with Tartrate Bound | Descriptor: | ATP-citrate synthase, L(+)-TARTARIC ACID, MAGNESIUM ION | Authors: | Fraser, M.E, Sun, T. | Deposit date: | 2010-05-05 | Release date: | 2010-06-16 | Last modified: | 2011-07-13 | Method: | X-RAY DIFFRACTION (2.2 Å) | Cite: | Identification of the citrate-binding site of human ATP-citrate lyase using X-ray crystallography. J.Biol.Chem., 285, 2010
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8G5C
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5TET
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5TE1
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3PFF
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5TEQ
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8G1F
| Structure of ACLY-D1026A-products | Descriptor: | (3S)-citryl-Coenzyme A, ACETYL COENZYME *A, ADENOSINE-5'-DIPHOSPHATE, ... | Authors: | Wei, X, Marmorstein, R. | Deposit date: | 2023-02-02 | Release date: | 2023-05-10 | Last modified: | 2024-06-19 | Method: | ELECTRON MICROSCOPY (2.4 Å) | Cite: | Allosteric role of the citrate synthase homology domain of ATP citrate lyase. Nat Commun, 14, 2023
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5TES
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8G5D
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7RKZ
| Structure of ACLY D1026A-substrates-asym-int | Descriptor: | (3S)-citryl-Coenzyme A, ADENOSINE-5'-DIPHOSPHATE, ATP-citrate synthase, ... | Authors: | Wei, X, Marmorstein, R. | Deposit date: | 2021-07-22 | Release date: | 2023-05-10 | Last modified: | 2024-06-05 | Method: | ELECTRON MICROSCOPY (2.6 Å) | Cite: | Allosteric role of the citrate synthase homology domain of ATP citrate lyase. Nat Commun, 14, 2023
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7RMP
| Structure of ACLY D1026A - substrates-asym | Descriptor: | (3S)-citryl-Coenzyme A, ADENOSINE-5'-DIPHOSPHATE, ATP-citrate synthase, ... | Authors: | Wei, X, Marmorstein, R. | Deposit date: | 2021-07-28 | Release date: | 2023-05-10 | Last modified: | 2024-06-05 | Method: | ELECTRON MICROSCOPY (2.7 Å) | Cite: | Allosteric role of the citrate synthase homology domain of ATP citrate lyase. Nat Commun, 14, 2023
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8G1E
| Structure of ACLY-D1026A-products-asym | Descriptor: | (3S)-citryl-Coenzyme A, ACETYL COENZYME *A, ADENOSINE-5'-DIPHOSPHATE, ... | Authors: | Wei, X, Marmorstein, R. | Deposit date: | 2023-02-02 | Release date: | 2023-05-10 | Last modified: | 2024-06-19 | Method: | ELECTRON MICROSCOPY (2.8 Å) | Cite: | Allosteric role of the citrate synthase homology domain of ATP citrate lyase. Nat Commun, 14, 2023
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7LIW
| Local refinement of human ATP citrate lyase E599Q mutant ASH domain | Descriptor: | (2S)-2-hydroxy-2-[2-oxo-2-(phosphonooxy)ethyl]butanedioic acid, ADENOSINE-5'-DIPHOSPHATE, ATP-citrate synthase, ... | Authors: | Wei, X, Marmorstein, R. | Deposit date: | 2021-01-28 | Release date: | 2021-05-19 | Last modified: | 2024-05-29 | Method: | ELECTRON MICROSCOPY (2.85 Å) | Cite: | Reply to: Acetyl-CoA is produced by the citrate synthase homology module of ATP-citrate lyase. Nat.Struct.Mol.Biol., 28, 2021
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6UUW
| Structure of human ATP citrate lyase E599Q mutant in complex with Mg2+, citrate, ATP and CoA | Descriptor: | (2S)-2-hydroxy-2-[2-oxo-2-(phosphonooxy)ethyl]butanedioic acid, ADENOSINE-5'-DIPHOSPHATE, ATP-citrate synthase, ... | Authors: | Wei, X, Marmorstein, R. | Deposit date: | 2019-11-01 | Release date: | 2019-12-25 | Last modified: | 2024-05-29 | Method: | ELECTRON MICROSCOPY (2.85 Å) | Cite: | Molecular basis for acetyl-CoA production by ATP-citrate lyase Nat.Struct.Mol.Biol., 27, 2020
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7LLA
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