8CR5
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![BU of 8cr5 by Molmil](/molmil-images/mine/8cr5) | Murine Interleukin-12 receptor beta 1 domain 1 in complex with murine Interleukin-12 beta. | Descriptor: | 2-acetamido-2-deoxy-beta-D-glucopyranose, Interleukin-12 receptor subunit beta-1, Interleukin-12 subunit beta, ... | Authors: | Merceron, R, Bloch, Y, Felix, J, Savvides, S.N. | Deposit date: | 2023-03-07 | Release date: | 2024-02-07 | Last modified: | 2024-05-01 | Method: | X-RAY DIFFRACTION (2.15 Å) | Cite: | Structures of complete extracellular receptor assemblies mediated by IL-12 and IL-23. Nat.Struct.Mol.Biol., 31, 2024
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8C7M
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![BU of 8c7m by Molmil](/molmil-images/mine/8c7m) | |
8CR6
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![BU of 8cr6 by Molmil](/molmil-images/mine/8cr6) | mouse Interleukin-12 | Descriptor: | 2-acetamido-2-deoxy-beta-D-glucopyranose, Interleukin-12 subunit alpha, Interleukin-12 subunit beta, ... | Authors: | Merceron, R, Felix, J, Lambert, E, Bloch, Y, Savvides, S.N. | Deposit date: | 2023-03-07 | Release date: | 2024-02-07 | Last modified: | 2024-05-01 | Method: | X-RAY DIFFRACTION (2.85 Å) | Cite: | Structures of complete extracellular receptor assemblies mediated by IL-12 and IL-23. Nat.Struct.Mol.Biol., 31, 2024
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8ODX
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![BU of 8odx by Molmil](/molmil-images/mine/8odx) | |
8OE4
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![BU of 8oe4 by Molmil](/molmil-images/mine/8oe4) | Cryo-EM structure of a pre-dimerized human IL-23 complete extracellular signaling complex. | Descriptor: | 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, Interleukin-12 receptor subunit beta-1,Death-associated protein kinase 1, ... | Authors: | Bloch, Y, Felix, J, Savvides, S.N. | Deposit date: | 2023-03-10 | Release date: | 2024-02-07 | Last modified: | 2024-05-01 | Method: | ELECTRON MICROSCOPY (3.6 Å) | Cite: | Structures of complete extracellular receptor assemblies mediated by IL-12 and IL-23. Nat.Struct.Mol.Biol., 31, 2024
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8ODZ
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![BU of 8odz by Molmil](/molmil-images/mine/8odz) | Cryo-EM structure of a pre-dimerized murine IL-12 complete extracellular signaling complex (Class 1). | Descriptor: | 2-acetamido-2-deoxy-beta-D-glucopyranose, Interleukin-12 receptor subunit beta-1,Death-associated protein kinase 1, Interleukin-12 receptor subunit beta-2,Calmodulin-1, ... | Authors: | Felix, J, Bloch, Y, Savvides, S.N. | Deposit date: | 2023-03-10 | Release date: | 2024-02-07 | Last modified: | 2024-05-01 | Method: | ELECTRON MICROSCOPY (3.6 Å) | Cite: | Structures of complete extracellular receptor assemblies mediated by IL-12 and IL-23. Nat.Struct.Mol.Biol., 31, 2024
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8OE0
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![BU of 8oe0 by Molmil](/molmil-images/mine/8oe0) | Cryo-EM structure of a pre-dimerized murine IL-12 complete extracellular signaling complex (Class 2). | Descriptor: | 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, Interleukin-12 receptor subunit beta-1,Death-associated protein kinase 1, ... | Authors: | Felix, J, Bloch, Y, Savvides, S.N. | Deposit date: | 2023-03-10 | Release date: | 2024-02-07 | Last modified: | 2024-05-01 | Method: | ELECTRON MICROSCOPY (4.6 Å) | Cite: | Structures of complete extracellular receptor assemblies mediated by IL-12 and IL-23. Nat.Struct.Mol.Biol., 31, 2024
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8PPM
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![BU of 8ppm by Molmil](/molmil-images/mine/8ppm) | IL-12Rb1 neutralizing Fab4, crystal kappa variant | Descriptor: | Fab4 Light chain, crystal kappa variant, Fab4 heavy chain, ... | Authors: | Bloch, Y, Savvides, S.N. | Deposit date: | 2023-07-07 | Release date: | 2024-02-07 | Last modified: | 2024-05-01 | Method: | X-RAY DIFFRACTION (2.03 Å) | Cite: | Structures of complete extracellular receptor assemblies mediated by IL-12 and IL-23. Nat.Struct.Mol.Biol., 31, 2024
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8PB1
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![BU of 8pb1 by Molmil](/molmil-images/mine/8pb1) | Cryo-EM structure of a pre-dimerized murine IL-12 complete extracellular signaling complex (Class 1), obtained after local refinement. | Descriptor: | 2-acetamido-2-deoxy-beta-D-glucopyranose, Interleukin-12 receptor subunit beta-1,Death-associated protein kinase 1, Interleukin-12 receptor subunit beta-2,Calmodulin-1, ... | Authors: | Felix, J, Bloch, Y, Savvides, S.N. | Deposit date: | 2023-06-08 | Release date: | 2024-02-07 | Last modified: | 2024-05-01 | Method: | ELECTRON MICROSCOPY (3.5 Å) | Cite: | Structures of complete extracellular receptor assemblies mediated by IL-12 and IL-23. Nat.Struct.Mol.Biol., 31, 2024
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8CR8
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![BU of 8cr8 by Molmil](/molmil-images/mine/8cr8) | human Interleukin-23 | Descriptor: | Interleukin-12 subunit beta, Interleukin-23 subunit alpha, TERBIUM(III) ION, ... | Authors: | Bloch, Y, Savvides, S.N. | Deposit date: | 2023-03-08 | Release date: | 2024-02-07 | Last modified: | 2024-05-01 | Method: | X-RAY DIFFRACTION (2 Å) | Cite: | Structures of complete extracellular receptor assemblies mediated by IL-12 and IL-23. Nat.Struct.Mol.Biol., 31, 2024
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