PDB: 229 resultsInfo pagesStatus searchChemie searchBIRD

---

4UAI	Crystal structure of CXCL12 in complex with inhibitor Descriptor: 1-phenyl-3-[4-(1H-tetrazol-5-yl)phenyl]urea, SULFATE ION, Stromal cell-derived factor 1 Authors: Smith, E.W, Chen, Y. Deposit date: 2014-08-09 Release date: 2014-11-12 Last modified: 2023-09-27 Method: X-RAY DIFFRACTION (1.9 Å) Cite: Structural Analysis of a Novel Small Molecule Ligand Bound to the CXCL12 Chemokine. J.Med.Chem., 57, 2014
5OB5	fAb complex with GroBeta. AbVance: increasing our knowledge of antibody structural space to enable faster and better decision-making in antibody drug discovery. Descriptor: C-X-C motif chemokine 2, GLYCEROL, SULFATE ION, ... Authors: Zhao, B, Ward, P, Convery, M.A. Deposit date: 2017-06-26 Release date: 2017-11-08 Method: X-RAY DIFFRACTION (1.65 Å) Cite: AbVance: increasing our knowledge of antibody structural space to enable faster and better decision-making in antibody drug discovery To Be Published
4DN4	Crystal structure of the complex between cnto888 fab and mcp-1 mutant p8a Descriptor: ACETATE ION, C-C motif chemokine 2, CNTO888 HEAVY CHAIN, ... Authors: Obmolova, G, Teplyakov, A, Malia, T, Grygiel, T, Sweet, R, Snyder, L, Gilliland, G. Deposit date: 2012-02-08 Release date: 2012-10-03 Last modified: 2018-01-24 Method: X-RAY DIFFRACTION (2.8 Å) Cite: Structural basis for high selectivity of anti-CCL2 neutralizing antibody CNTO 888. Mol.Immunol., 51, 2012
6VGJ	N-terminal variant of CXCL13 Descriptor: C-X-C motif chemokine 13 Authors: Rosenberg Jr, E.M, Lolis, E.J. Deposit date: 2020-01-08 Release date: 2020-10-07 Last modified: 2023-10-11 Method: X-RAY DIFFRACTION (2.52 Å) Cite: The N-terminal length and side-chain composition of CXCL13 affect crystallization, structure and functional activity. Acta Crystallogr D Struct Biol, 76, 2020
7JNY	Crystal structure of CXCL13 Descriptor: C-X-C motif chemokine 13 Authors: Rosenberg Jr, E.M, Rajasekaran, D, Murphy, J.W, Pantouris, G, Lolis, E.J. Deposit date: 2020-08-05 Release date: 2020-10-07 Last modified: 2023-10-18 Method: X-RAY DIFFRACTION (1.88 Å) Cite: The N-terminal length and side-chain composition of CXCL13 affect crystallization, structure and functional activity. Acta Crystallogr D Struct Biol, 76, 2020
5IZB	Murin CXCL13 solution structure featuring a folded N-terminal domain Descriptor: C-X-C motif chemokine 13 Authors: Monneau, Y.R, Lortat-Jacob, H. Deposit date: 2016-03-25 Release date: 2017-04-05 Last modified: 2023-06-14 Method: SOLUTION NMR Cite: Murin CXCL13 solution structure featuring a folded N-terminal domain To be published
1ZXT	Crystal Structure of A Viral Chemokine Descriptor: functional macrophage inflammatory protein 1-alpha homolog Authors: Luz, J.G, Yu, M, Su, Y, Wu, Z, Zhou, Z, Sun, R, Wilson, I.A. Deposit date: 2005-06-08 Release date: 2005-08-30 Last modified: 2023-08-23 Method: X-RAY DIFFRACTION (1.7 Å) Cite: Crystal structure of viral macrophage inflammatory protein I encoded by Kaposi's sarcoma-associated herpesvirus at 1.7A. J.Mol.Biol., 352, 2005
3TN2	structure analysis of MIP1-beta P8A Descriptor: C-C motif chemokine 4, ZINC ION Authors: Guo, Q, Tang, W.J. Deposit date: 2011-09-01 Release date: 2012-09-05 Last modified: 2018-08-22 Method: X-RAY DIFFRACTION (1.6 Å) Cite: Structures of human CCL18, CCL3, and CCL4 reveal molecular determinants for quaternary structures and sensitivity to insulin-degrading enzyme. J.Mol.Biol., 427, 2015
5D65	X-RAY STRUCTURE OF MACROPHAGE INFLAMMATORY PROTEIN-1 ALPHA (CCL3) WITH HEPARIN COMPLEX Descriptor: 2-deoxy-6-O-sulfo-2-(sulfoamino)-alpha-D-glucopyranose-(1-4)-2-O-sulfo-alpha-L-idopyranuronic acid, C-C motif chemokine 3, CHLORIDE ION, ... Authors: Liang, W.G, Hwang, D.Y, Zulueta, M.M, Hung, S.C, Tang, W. Deposit date: 2015-08-11 Release date: 2016-04-20 Last modified: 2023-09-27 Method: X-RAY DIFFRACTION (3.1 Å) Cite: Structural basis for oligomerization and glycosaminoglycan binding of CCL5 and CCL3. Proc.Natl.Acad.Sci.USA, 113, 2016
5D14	The atomic resolution crystal structure of human IL-8 Descriptor: Interleukin-8 Authors: Brzezinski, K, Pompeu, Y, Lu, S, Jakoncic, J, Ostrov, D.A. Deposit date: 2015-08-03 Release date: 2015-12-23 Last modified: 2017-11-22 Method: X-RAY DIFFRACTION (1 Å) Cite: The atomic resolution crystal structure of human IL-8 To Be Published
4OIK	(Quasi-)Racemic X-ray crystal structure of glycosylated chemokine Ser-CCL1. Descriptor: 2-acetamido-2-deoxy-beta-D-glucopyranose, C-C motif chemokine 1, CITRIC ACID, ... Authors: Okamoto, R, Mandal, K, Sawaya, M.R, Kajihara, Y, Yeates, T.O, Kent, S.B.H. Deposit date: 2014-01-19 Release date: 2014-05-07 Last modified: 2023-12-06 Method: X-RAY DIFFRACTION (2.1 Å) Cite: (Quasi-)Racemic X-ray Structures of Glycosylated and Non-Glycosylated Forms of the Chemokine Ser-CCL1 Prepared by Total Chemical Synthesis. Angew.Chem.Int.Ed.Engl., 53, 2014
5DNF	Crystal structure of CC chemokine 5 (CCL5) oligomer in complex with heparin Descriptor: 2-AMINO-2-HYDROXYMETHYL-PROPANE-1,3-DIOL, 2-deoxy-6-O-sulfo-2-(sulfoamino)-alpha-D-glucopyranose-(1-4)-2-O-sulfo-alpha-L-idopyranuronic acid-(1-4)-2-deoxy-6-O-sulfo-2-(sulfoamino)-alpha-D-glucopyranose, C-C motif chemokine 5, ... Authors: Liang, W.G, Tang, W. Deposit date: 2015-09-10 Release date: 2016-04-13 Last modified: 2020-07-29 Method: X-RAY DIFFRACTION (2.549 Å) Cite: Structural basis for oligomerization and glycosaminoglycan binding of CCL5 and CCL3. Proc.Natl.Acad.Sci.USA, 113, 2016
4OIJ	X-ray crystal structure of racemic non-glycosylated chemokine Ser-CCL1 Descriptor: C-C motif chemokine 1, D-Ser-CCL1, SULFATE ION Authors: Okamoto, R, Mandal, K, Sawaya, M.R, Kajihara, Y, Yeates, T.O, Kent, S.B.H. Deposit date: 2014-01-19 Release date: 2014-05-07 Last modified: 2014-05-21 Method: X-RAY DIFFRACTION (2 Å) Cite: (Quasi-)Racemic X-ray Structures of Glycosylated and Non-Glycosylated Forms of the Chemokine Ser-CCL1 Prepared by Total Chemical Synthesis. Angew.Chem.Int.Ed.Engl., 53, 2014
6LOG	Crystal structure of human CCL5-12AAA14 mutant Descriptor: C-C motif chemokine 5 Authors: Chen, Y.C, Li, J.Y, Huang, C.H, Sue, S.C. Deposit date: 2020-01-05 Release date: 2020-03-18 Last modified: 2023-11-29 Method: X-RAY DIFFRACTION (2.55 Å) Cite: N-terminal Backbone Pairing Shifts in CCL5- 12 AAA 14 Dimer Interface: Structural Significance of the FAY Sequence. Int J Mol Sci, 21, 2020
6EHZ	NMR solution structure of murine CXCL12 gamma isoform Descriptor: Stromal cell-derived factor 1 Authors: Laguri, C, Lortat-Jacob, H, SImorre, J.P. Deposit date: 2017-09-15 Release date: 2018-10-10 Last modified: 2023-06-14 Method: SOLUTION NMR Cite: Deciphering the structural attributes of protein-heparan sulfate interactions using chemo-enzymatic approaches and NMR spectroscopy Glycobiology, 2021
6SHR	X-RAY CRYSTAL STRUCTURE OF CELL-FREE PROTEIN SYNTHESIS (CFPS) PRODUCED SDF1-A Descriptor: Stromal cell-derived factor 1 Authors: Jugnarain, V.M, Mitchell, E, Forsyth, T, Michael, H, Cortes, S, Tillier, B. Deposit date: 2019-08-08 Release date: 2020-08-26 Last modified: 2024-01-24 Method: X-RAY DIFFRACTION (1.745 Å) Cite: X-RAY CRYSTAL STRUCTURE OF CELL-FREE PROTEIN SYNTHESIS (CFPS) PRODUCED SDF1-A To Be Published
4LMQ	Development and Preclinical Characterization of a Humanized Antibody Targeting CXCL12 Descriptor: Stromal cell-derived factor 1, hu30D8 Fab heavy chain, hu30D8 Fab light chain Authors: Zhong, Z, Wang, J, Li, B, Xiang, H, Ultsch, M, Coons, M, Wong, T, Chiang, N.Y, Clark, S, Clark, R, Quintana, L, Gribling, P, Suto, E, Barck, K, Corpuz, R, Yao, J, Takkar, R, Lee, W.P, Damico-Beyer, L.A, Carano, R.D, Adams, C, Kelley, R.F, Wang, W, Ferrara, N. Deposit date: 2013-07-10 Release date: 2013-08-14 Last modified: 2021-10-27 Method: X-RAY DIFFRACTION (2.773 Å) Cite: Development and Preclinical Characterization of a Humanized Antibody Targeting CXCL12. Clin.Cancer Res., 19, 2013
4MHE	Crystal structure of CC-chemokine 18 Descriptor: ACETATE ION, C-C motif chemokine 18 Authors: Liang, W.G, Tang, W.-J. Deposit date: 2013-08-29 Release date: 2014-09-03 Last modified: 2023-09-20 Method: X-RAY DIFFRACTION (2.1 Å) Cite: Structures of human CCL18, CCL3, and CCL4 reveal molecular determinants for quaternary structures and sensitivity to insulin-degrading enzyme. J.Mol.Biol., 427, 2015
6STK	Crystal structure of the CC-chemokine 5 (CCL5) E66S mutation Descriptor: ACETATE ION, C-C motif chemokine 5, GLYCEROL Authors: Ramirez-Escudero, M, Janssen, B.J.C. Deposit date: 2019-09-10 Release date: 2020-09-02 Last modified: 2024-01-24 Method: X-RAY DIFFRACTION (1.52 Å) Cite: Structural characterization of anti-CCL5 activity of the tick salivary protein evasin-4. J.Biol.Chem., 295, 2020
5EKI	Crystal Structure of Truncated CCL21 Descriptor: C-C motif chemokine 21, SULFATE ION Authors: Lewandowski, E.M, Smith, E.W, Chen, Y. Deposit date: 2015-11-03 Release date: 2016-10-05 Last modified: 2019-12-04 Method: X-RAY DIFFRACTION (1.9 Å) Cite: Crystallographic Structure of Truncated CCL21 and the Putative Sulfotyrosine-Binding Site. Biochemistry, 55, 2016
6FGP	NMR solution structure of monomeric CCL5 in complex with a doubly-sulfated N-terminal segment of CCR5 Descriptor: C-C chemokine receptor type 5, C-C motif chemokine 5 Authors: Anglister, J, Abayev, M. Deposit date: 2018-01-11 Release date: 2018-04-18 Last modified: 2022-03-30 Method: SOLUTION NMR Cite: The solution structure of monomeric CCL5 in complex with a doubly sulfated N-terminal segment of CCR5. FEBS J., 285, 2018
3N52	crystal Structure analysis of MIP2 Descriptor: C-X-C motif chemokine 2 Authors: Rajasekaran, D. Deposit date: 2010-05-24 Release date: 2011-06-08 Last modified: 2017-11-08 Method: X-RAY DIFFRACTION (1.9 Å) Cite: A Model of GAG/MIP-2/CXCR2 Interfaces and Its Functional Effects. Biochemistry, 51, 2012
6N2U	IL-8 Structure from Bacterial Expression Source Descriptor: Interleukin-8 Authors: Park, H, Jung, J.H, Luo, J.L. Deposit date: 2018-11-14 Release date: 2019-11-20 Last modified: 2023-10-11 Method: X-RAY DIFFRACTION (1.254 Å) Cite: IL-8 Structure from Bacterial Expression Source To Be Published
5UR7	Crystal structure of engineered CCL20 disulfide locked dimer Descriptor: ACETATE ION, C-C motif chemokine 20, ISOPROPYL ALCOHOL Authors: Getschman, A.E, Peterson, F.C, Volkman, B.F. Deposit date: 2017-02-09 Release date: 2017-11-22 Last modified: 2023-10-04 Method: X-RAY DIFFRACTION (2.0004 Å) Cite: Protein engineering of the chemokine CCL20 prevents psoriasiform dermatitis in an IL-23-dependent murine model. Proc. Natl. Acad. Sci. U.S.A., 114, 2017
3GV3	CXCL12 (SDF) in trigonal space group Descriptor: CXCL12 protein Authors: Murphy, J.W, Crichlow, G, Lolis, E. Deposit date: 2009-03-30 Release date: 2010-01-26 Last modified: 2021-10-13 Method: X-RAY DIFFRACTION (1.6 Å) Cite: Heterologous quaternary structure of CXCL12 and its relationship to the CC chemokine family. Proteins, 78, 2009

 

12345678910>