4UAI
Crystal structure of CXCL12 in complex with inhibitor
Summary for 4UAI
Entry DOI | 10.2210/pdb4uai/pdb |
Descriptor | Stromal cell-derived factor 1, 1-phenyl-3-[4-(1H-tetrazol-5-yl)phenyl]urea, SULFATE ION, ... (4 entities in total) |
Functional Keywords | cxcl12, inhibitor, complex, chemokine, cytokine-cytokine inhibitor complex, cytokine/cytokine inhibitor |
Biological source | Homo sapiens (Human) |
Total number of polymer chains | 2 |
Total formula weight | 16429.33 |
Authors | Smith, E.W.,Chen, Y. (deposition date: 2014-08-09, release date: 2014-11-12, Last modification date: 2023-09-27) |
Primary citation | Smith, E.W.,Liu, Y.,Getschman, A.E.,Peterson, F.C.,Ziarek, J.J.,Li, R.,Volkman, B.F.,Chen, Y. Structural Analysis of a Novel Small Molecule Ligand Bound to the CXCL12 Chemokine. J.Med.Chem., 57:9693-9699, 2014 Cited by PubMed: 25356720DOI: 10.1021/jm501194p PDB entries with the same primary citation |
Experimental method | X-RAY DIFFRACTION (1.9 Å) |
Structure validation
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