PDB: 46200 resultsInfo pagesStatus searchChemie searchBIRD

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2J9M	Crystal Structure of CDK2 in complex with Macrocyclic Aminopyrimidine Descriptor: 6-BROMO-13-THIA-2,4,8,12,19-PENTAAZATRICYCLO[12.3.1.1~3,7~]NONADECA-1(18),3(19),4,6,14,16-HEXAENE 13,13-DIOXIDE, CELL DIVISION PROTEIN KINASE 2 Authors: Schaefer, M, Luecking, U, Siemeister, G, Briem, H, Krueger, M, Lienau, P, Jautelat, R. Deposit date: 2006-11-13 Release date: 2007-11-06 Last modified: 2023-12-13 Method: X-RAY DIFFRACTION (2.5 Å) Cite: Macrocyclic Aminopyrimidines as Multitarget Cdk and Vegf-R Inhibitors with Potent Antiproliferative Activities. Chemmedchem, 2, 2007
5MMI	Structure of the large subunit of the chloroplast ribosome Descriptor: 23S ribosomal RNA, 4.5S ribosomal RNA, 50S ribosomal protein 6, ... Authors: Bieri, P, Leibundgut, M, Saurer, M, Boehringer, D, Ban, N. Deposit date: 2016-12-10 Release date: 2017-01-11 Last modified: 2024-05-15 Method: ELECTRON MICROSCOPY (3.2 Å) Cite: The complete structure of the chloroplast 70S ribosome in complex with translation factor pY. EMBO J., 36, 2017
6W7N	30S-Inactive-low-Mg2+ Class A Descriptor: 16S rRNA, 30S ribosomal protein S10, 30S ribosomal protein S12, ... Authors: Jahagirdar, D, Jha, V, Basu, B, Gomez-Blanco, J, Vargas, J, Ortega, J. Deposit date: 2020-03-19 Release date: 2020-10-21 Last modified: 2024-03-06 Method: ELECTRON MICROSCOPY (3.4 Å) Cite: Alternative conformations and motions adopted by 30S ribosomal subunits visualized by cryo-electron microscopy. Rna, 26, 2020
6W6K	30S-Activated-high-Mg2+ Descriptor: 16S rRNA, 30S ribosomal protein S10, 30S ribosomal protein S11, ... Authors: Jahagirdar, D, Jha, V, Basu, B, Gomez-Blanco, J, Vargas, J, Ortega, J. Deposit date: 2020-03-17 Release date: 2020-10-21 Last modified: 2024-03-06 Method: ELECTRON MICROSCOPY (3.6 Å) Cite: Alternative conformations and motions adopted by 30S ribosomal subunits visualized by cryo-electron microscopy. Rna, 26, 2020
6W77	30S-Inactivated-high-Mg2+ Class A Descriptor: 30S ribosomal protein S10, 30S ribosomal protein S11, 30S ribosomal protein S12, ... Authors: Jahagirdar, D, Jha, V, Basu, B, Gomez-Blanco, J, Vargas, J, Ortega, J. Deposit date: 2020-03-18 Release date: 2020-10-21 Last modified: 2024-03-06 Method: ELECTRON MICROSCOPY (3.6 Å) Cite: Alternative conformations and motions adopted by 30S ribosomal subunits visualized by cryo-electron microscopy. Rna, 26, 2020
7NAV	Bacterial 30S ribosomal subunit assembly complex state D (Consensus refinement) Descriptor: 16S rRNA, 30S ribosomal protein S10, 30S ribosomal protein S11, ... Authors: Schedlbauer, A, Iturrioz, I, Ochoa-Lizarralde, B, Diercks, T, Kaminishi, T, Capuni, R, Astigarraga, E, Gil-Carton, D, Fucini, P, Connell, S. Deposit date: 2021-01-25 Release date: 2021-12-08 Last modified: 2024-04-24 Method: ELECTRON MICROSCOPY (4.8 Å) Cite: A conserved rRNA switch is central to decoding site maturation on the small ribosomal subunit. Sci Adv, 7, 2021
7N9F	Structure of the in situ yeast NPC Descriptor: Dynein light chain 1, cytoplasmic, Nucleoporin 145c, ... Authors: Villa, E, Singh, D, Ludtke, S.J, Akey, C.W, Rout, M.P, Echeverria, I, Suslov, S. Deposit date: 2021-06-17 Release date: 2022-01-26 Last modified: 2024-06-05 Method: ELECTRON MICROSCOPY (37 Å) Cite: Comprehensive structure and functional adaptations of the yeast nuclear pore complex. Cell, 185, 2022
6W7M	30S-Inactive-high-Mg2+ + carbon layer Descriptor: 16S rRNA, 30S ribosomal protein S10, 30S ribosomal protein S11, ... Authors: Jahagirdar, D, Jha, V, Basu, B, Gomez-Blanco, J, Vargas, J, Ortega, J. Deposit date: 2020-03-19 Release date: 2020-10-21 Last modified: 2024-03-06 Method: ELECTRON MICROSCOPY (3.8 Å) Cite: Alternative conformations and motions adopted by 30S ribosomal subunits visualized by cryo-electron microscopy. Rna, 26, 2020
2XU7	Structural basis for RbAp48 binding to FOG-1 Descriptor: HISTONE-BINDING PROTEIN RBBP4, TETRAETHYLENE GLYCOL, ZINC FINGER PROTEIN ZFPM1 Authors: Lejon, S, Thong, S.Y, Murthy, A, Blobel, G.A, Mackay, J.P, Murzina, N.V, Laue, E.D. Deposit date: 2010-10-15 Release date: 2010-11-03 Last modified: 2023-12-20 Method: X-RAY DIFFRACTION (1.9 Å) Cite: Insights Into Association of the Nurd Complex with Fog-1 from the Crystal Structure of an Rbap48-Fog- 1 Complex. J.Biol.Chem., 286, 2011
2DLL	Solution structure of the IRF domain of human interferon regulator factors 4 Descriptor: Interferon regulatory factor 4 Authors: Zhang, H.P, Kurosaki, C, Yoshida, M, Hayashi, F, Yokoyama, S, RIKEN Structural Genomics/Proteomics Initiative (RSGI) Deposit date: 2006-04-20 Release date: 2006-10-20 Last modified: 2024-05-29 Method: SOLUTION NMR Cite: Solution structure of the IRF domain of human interferon regulator factors 4 To be published
2MT4	Solution structure of the N-terminal domain of NUSA from B. Subtilis Descriptor: Transcription termination/antitermination protein NusA Authors: Mobli, M, Lewis, P.J. Deposit date: 2014-08-12 Release date: 2015-02-18 Last modified: 2024-05-15 Method: SOLUTION NMR Cite: RNA polymerase-induced remodelling of NusA produces a pause enhancement complex. Nucleic Acids Res., 43, 2015
5NJT	Structure of the Bacillus subtilis hibernating 100S ribosome reveals the basis for 70S dimerization. Descriptor: 16S ribosomal RNA, 23S ribosomal RNA, 30S ribosomal protein S10, ... Authors: Beckert, B, Abdelshahid, M, Schaefer, H, Steinchen, W, Arenz, S, Berninghausen, O, Beckmann, R, Bange, G, Turgay, K, Wilson, D.N. Deposit date: 2017-03-29 Release date: 2017-06-14 Last modified: 2024-05-15 Method: ELECTRON MICROSCOPY (3.8 Å) Cite: Structure of the Bacillus subtilis hibernating 100S ribosome reveals the basis for 70S dimerization. EMBO J., 36, 2017
5Y88	Cryo-EM structure of the intron-lariat spliceosome ready for disassembly from S.cerevisiae at 3.5 angstrom Descriptor: GUANOSINE-5'-TRIPHOSPHATE, INOSITOL HEXAKISPHOSPHATE, Intron lariat, ... Authors: Wan, R, Yan, C, Bai, R, Lei, J, Shi, Y. Deposit date: 2017-08-20 Release date: 2018-08-01 Last modified: 2024-03-27 Method: ELECTRON MICROSCOPY (3.46 Å) Cite: Structure of an Intron Lariat Spliceosome from Saccharomyces cerevisiae Cell(Cambridge,Mass.), 171, 2017
5NDJ	Crystal structure of aminoglycoside TC007 in complex with 70S ribosome from Thermus thermophilus, three tRNAs and mRNA (soaking) Descriptor: 16S ribosomal RNA, 23S ribosomal RNA, 30S ribosomal protein S10, ... Authors: Prokhorova, I, Djumagulov, M, Urzhumtsev, A, Yusupov, M, Yusupova, G. Deposit date: 2017-03-08 Release date: 2018-05-02 Last modified: 2024-05-08 Method: X-RAY DIFFRACTION (3.15 Å) Cite: Aminoglycoside interactions and impacts on the eukaryotic ribosome. Proc. Natl. Acad. Sci. U.S.A., 114, 2017
3J7Z	Structure of the E. coli 50S subunit with ErmCL nascent chain Descriptor: 23S rRNA, 50S ribosomal protein L10, 50S ribosomal protein L11, ... Authors: Arenz, S, Meydan, S, Starosta, A.L, Berninghausen, O, Beckmann, R, Vazquez-Laslop, N, Wilson, D.N. Deposit date: 2014-08-27 Release date: 2014-10-22 Last modified: 2018-07-18 Method: ELECTRON MICROSCOPY (3.9 Å) Cite: Drug Sensing by the Ribosome Induces Translational Arrest via Active Site Perturbation. Mol.Cell, 56, 2014
3J8G	Electron cryo-microscopy structure of EngA bound with the 50S ribosomal subunit Descriptor: 23S rRNA, 50S ribosomal protein L1, 50S ribosomal protein L11, ... Authors: Zhang, X, Yan, K, Zhang, Y, Li, N, Ma, C, Li, Z, Zhang, Y, Feng, B, Liu, J, Sun, Y, Xu, Y, Lei, J, Gao, N. Deposit date: 2014-10-24 Release date: 2014-11-26 Last modified: 2024-03-20 Method: ELECTRON MICROSCOPY (5 Å) Cite: Structural insights into the function of a unique tandem GTPase EngA in bacterial ribosome assembly Nucleic Acids Res., 2014
5NDK	Crystal structure of aminoglycoside TC007 co-crystallized with 70S ribosome from Thermus thermophilus, three tRNAs and mRNA Descriptor: 16S ribosomal RNA, 23S ribosomal RNA, 30S ribosomal protein S10, ... Authors: Prokhorova, I, Djumagulov, M, Urzhumtsev, A, Yusupov, M, Yusupova, G. Deposit date: 2017-03-08 Release date: 2017-12-13 Last modified: 2024-05-08 Method: X-RAY DIFFRACTION (2.95 Å) Cite: Aminoglycoside interactions and impacts on the eukaryotic ribosome. Proc. Natl. Acad. Sci. U.S.A., 114, 2017
2O7H	Crystal structure of trimeric coiled coil GCN4 leucine zipper Descriptor: General control protein GCN4 Authors: Jawhari, H, Honnappa, S, Steinmetz, M.O. Deposit date: 2006-12-11 Release date: 2007-11-27 Last modified: 2023-10-25 Method: X-RAY DIFFRACTION (1.86 Å) Cite: Molecular basis of coiled-coil oligomerization-state specificity Proc.Natl.Acad.Sci.USA, 107, 2010
6WEG	Structure of Ft (MglA-SspA)-ppGpp-PigR peptide complex Descriptor: GUANOSINE-5',3'-TETRAPHOSPHATE, MAGNESIUM ION, MglA, ... Authors: Schumacher, M.A, Brennan, R. Deposit date: 2020-04-02 Release date: 2020-11-11 Last modified: 2023-10-18 Method: X-RAY DIFFRACTION (2.95 Å) Cite: Structural Basis for Virulence Activation of Francisella tularensis. Mol.Cell, 81, 2021
2I40	Cdk2/Cyclin A complexed with a thiophene carboxamide inhibitor Descriptor: 5-[5,6-BIS(METHYLOXY)-1H-BENZIMIDAZOL-1-YL]-3-{[1-(2-CHLOROPHENYL)ETHYL]OXY}-2-THIOPHENECARBOXAMIDE, Cell division protein kinase 2, Cyclin-A2 Authors: Shewchuk, L.M. Deposit date: 2006-08-21 Release date: 2006-10-10 Last modified: 2023-08-30 Method: X-RAY DIFFRACTION (2.8 Å) Cite: 5-(1H-Benzimidazol-1-yl)-3-alkoxy-2-thiophenecarbonitriles as potent, selective, inhibitors of IKK-epsilon kinase Bioorg.Med.Chem.Lett., 16, 2006
8B3Z	SigE N-terminal Domain Descriptor: RNA polymerase sigma factor Authors: Evans, N.J, Isaacson, R.L, Collins, K.M, Camp, A.H. Deposit date: 2022-09-18 Release date: 2023-08-23 Last modified: 2023-08-30 Method: X-RAY DIFFRACTION (2.38 Å) Cite: Structural Analysis of Bacillus subtilis Sigma Factors. Microorganisms, 11, 2023
5DEQ	Crystal structure of transcriptional factor AraR from Bacteroides thetaiotaomicron VPI in complex with L-arabinose Descriptor: FORMIC ACID, SULFATE ION, TRANSCRIPTIONAL REGULATOR AraR, ... Authors: Chang, C, Tesar, C, Rodionov, D, Joachimiak, A, Midwest Center for Structural Genomics (MCSG) Deposit date: 2015-08-25 Release date: 2015-10-21 Last modified: 2020-07-29 Method: X-RAY DIFFRACTION (1.95 Å) Cite: A novel transcriptional regulator of L-arabinose utilization in human gut bacteria. Nucleic Acids Res., 43, 2015
5MSF	MS2 PROTEIN CAPSID/RNA COMPLEX Descriptor: 5'-R(*CP*CP*GP*GP*AP*GP*GP*AP*UP*CP*AP*CP*CP*AP*CP*GP*GP*G)-3', MS2 PROTEIN CAPSID Authors: Rowsell, S, Stonehouse, N.J, Convery, M.A, Adams, C.J, Ellington, A.D, Hirao, I, Peabody, D.S, Stockley, P.G, Phillips, S.E.V. Deposit date: 1998-05-15 Release date: 1998-11-11 Last modified: 2023-08-02 Method: X-RAY DIFFRACTION (2.8 Å) Cite: Crystal structures of a series of RNA aptamers complexed to the same protein target. Nat.Struct.Biol., 5, 1998
6VZ9	Structure of proline utilization A with the FAD covalently modified by L-thiazolidine-2-carboxylate Descriptor: (2S)-1,3-thiazolidine-2-carboxylic acid, Bifunctional protein PutA, DI(HYDROXYETHYL)ETHER, ... Authors: Campbell, A.C, Tanner, J.J. Deposit date: 2020-02-28 Release date: 2020-03-18 Last modified: 2023-10-11 Method: X-RAY DIFFRACTION (1.52 Å) Cite: Covalent Modification of the Flavin in Proline Dehydrogenase by Thiazolidine-2-Carboxylate. Acs Chem.Biol., 15, 2020
6RLQ	CRYSTAL STRUCTURE OF THE HUMAN PRMT5:MEP50 COMPLEX with JNJ45031882 Descriptor: (1~{S},2~{R},3~{S},5~{R})-3-[2-(2-azanyl-3-bromanyl-quinolin-7-yl)ethyl]-5-(4-azanylpyrrolo[2,3-d]pyrimidin-7-yl)cyclop entane-1,2-diol, Methylosome protein 50, Protein arginine N-methyltransferase 5 Authors: Brown, D.G, Robinson, C.M, Pande, V. Deposit date: 2019-05-02 Release date: 2020-07-15 Last modified: 2024-05-15 Method: X-RAY DIFFRACTION (2.53 Å) Cite: CRYSTAL STRUCTURE OF THE HUMAN PRMT5:MEP50 COMPLEX with JNJ45031882 To Be Published

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