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1DBK
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BU of 1dbk by Molmil
MOLECULAR BASIS OF CROSS-REACTIVITY AND THE LIMITS OF ANTIBODY-ANTIGEN COMPLEMENTARITY
Descriptor: 5-BETA-ANDROSTANE-3,17-DIONE, IGG1-KAPPA DB3 FAB (HEAVY CHAIN), IGG1-KAPPA DB3 FAB (LIGHT CHAIN)
Authors:Arevalo, J.H, Wilson, I.A.
Deposit date:1993-08-24
Release date:1994-01-31
Last modified:2024-06-05
Method:X-RAY DIFFRACTION (3 Å)
Cite:Molecular basis of crossreactivity and the limits of antibody-antigen complementarity.
Nature, 365, 1993
4OZG
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BU of 4ozg by Molmil
D2 protein complex
Descriptor: 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, CALCIUM ION, ...
Authors:Petersen, J, Reid, H.H, Rossjohn, J.
Deposit date:2014-02-16
Release date:2014-04-16
Last modified:2023-12-27
Method:X-RAY DIFFRACTION (3 Å)
Cite:T-cell receptor recognition of HLA-DQ2-gliadin complexes associated with celiac disease.
Nat.Struct.Mol.Biol., 21, 2014
5VIG
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BU of 5vig by Molmil
Crystal structure of anti-Zika antibody Z006 bound to Zika virus envelope protein DIII
Descriptor: CITRATE ANION, Fab heavy chain, Fab light chain, ...
Authors:Keeffe, J.R, West Jr, A.P, Gristick, H.B, Bjorkman, P.J.
Deposit date:2017-04-16
Release date:2017-05-03
Last modified:2017-05-17
Method:X-RAY DIFFRACTION (3 Å)
Cite:Recurrent Potent Human Neutralizing Antibodies to Zika Virus in Brazil and Mexico.
Cell, 169, 2017
3HG1
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BU of 3hg1 by Molmil
Germline-governed recognition of a cancer epitope by an immunodominant human T cell receptor
Descriptor: Beta-2-microglobulin, CANCER/MART-1, GLYCEROL, ...
Authors:Cole, D.K, Yuan, F, Rizkallah, P.J, Miles, J.J, Gostick, E, Price, D.A, Gao, G.F, Jakobsen, B.K, Sewell, A.K.
Deposit date:2009-05-13
Release date:2009-07-28
Last modified:2014-04-09
Method:X-RAY DIFFRACTION (3 Å)
Cite:Germ line-governed recognition of a cancer epitope by an immunodominant human T-cell receptor.
J.Biol.Chem., 284, 2009
1EFX
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BU of 1efx by Molmil
STRUCTURE OF A COMPLEX BETWEEN THE HUMAN NATURAL KILLER CELL RECEPTOR KIR2DL2 AND A CLASS I MHC LIGAND HLA-CW3
Descriptor: BETA-2-MICROGLOBULIN, HLA-CW3 (HEAVY CHAIN), NATURAL KILLER CELL RECEPTOR KIR2DL2, ...
Authors:Boyington, J.C, Motyka, S.A, Schuck, P, Brooks, A.G, Sun, P.D.
Deposit date:2000-02-10
Release date:2000-06-14
Last modified:2023-08-09
Method:X-RAY DIFFRACTION (3 Å)
Cite:Crystal structure of an NK cell immunoglobulin-like receptor in complex with its class I MHC ligand.
Nature, 405, 2000
7PBE
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BU of 7pbe by Molmil
Emergence of immune escape at dominant SARS-CoV-2 killer T-cell epitope
Descriptor: Beta-2-microglobulin, DI(HYDROXYETHYL)ETHER, Human T-cell Receptor YLQ36, ...
Authors:Rizkallah, P.J, Sewell, A.K, Wall, A, Fuller, A.
Deposit date:2021-08-02
Release date:2022-04-27
Last modified:2024-01-31
Method:X-RAY DIFFRACTION (3 Å)
Cite:Emergence of immune escape at dominant SARS-CoV-2 killer T cell epitope.
Cell, 185, 2022
3FB6
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BU of 3fb6 by Molmil
KcsA Potassium channel in the partially open state with 16 A opening at T112
Descriptor: POTASSIUM ION, Voltage-gated potassium channel, antibody fab fragment heavy chain, ...
Authors:Cuello, L.G, Jogini, V, Cortes, D.M, Perozo, E.
Deposit date:2008-11-18
Release date:2010-05-19
Last modified:2023-09-06
Method:X-RAY DIFFRACTION (3 Å)
Cite:KcsA Potassium channel in the partially open state with 16 A opening at T112
TO BE PUBLISHED
6AL5
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BU of 6al5 by Molmil
COMPLEX BETWEEN CD19 (N138Q MUTANT) AND B43 FAB
Descriptor: 2-acetamido-2-deoxy-beta-D-glucopyranose, B-lymphocyte antigen CD19, B43 HEAVY CHAIN, ...
Authors:Teplyakov, A, Obmolova, G, Gilliland, G.L.
Deposit date:2017-08-07
Release date:2018-03-28
Last modified:2023-10-04
Method:X-RAY DIFFRACTION (3 Å)
Cite:Crystal structure of B-cell co-receptor CD19 in complex with antibody B43 reveals an unexpected fold.
Proteins, 86, 2018
4Q6Y
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BU of 4q6y by Molmil
Crystal structure of a chemoenzymatic glycoengineered disialylated Fc (di-sFc)
Descriptor: 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-2)-alpha-D-mannopyranose-(1-3)-[2-acetamido-2-deoxy-beta-D-glucopyranose-(1-2)-alpha-D-mannopyranose-(1-6)]beta-D-mannopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, Ig gamma-1 chain C region, N-acetyl-alpha-neuraminic acid-(2-6)-beta-D-galactopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose-(1-2)-alpha-D-mannopyranose-(1-6)-[2-acetamido-2-deoxy-beta-D-glucopyranose-(1-2)-alpha-D-mannopyranose-(1-3)]beta-D-mannopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, ...
Authors:Ahmed, A.A, Giddens, J, Pincetic, A, Lomino, J.V, Ravetch, J.V, Wang, L.X, Bjorkman, P.J.
Deposit date:2014-04-23
Release date:2014-07-23
Last modified:2023-09-20
Method:X-RAY DIFFRACTION (3 Å)
Cite:Structural characterization of anti-inflammatory immunoglobulin g fc proteins.
J.Mol.Biol., 426, 2014
7RYO
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BU of 7ryo by Molmil
CD1a-dideoxymycobactin-gdTCR complex
Descriptor: 1,2-ETHANEDIOL, Beta-2-microglobulin, SULFATE ION, ...
Authors:Wegrecki, M, Le Nours, J, Rossjohn, J.
Deposit date:2021-08-25
Release date:2022-05-18
Last modified:2023-10-18
Method:X-RAY DIFFRACTION (3 Å)
Cite:Atypical sideways recognition of CD1a by autoreactive gamma delta T cell receptors.
Nat Commun, 13, 2022
6UEA
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BU of 6uea by Molmil
Structure of pentameric sIgA complex
Descriptor: 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, Immunoglobulin J chain, ...
Authors:Kumar, N, Arthur, C.P, Ciferri, C, Matsumoto, M.L.
Deposit date:2019-09-20
Release date:2020-02-19
Last modified:2020-07-29
Method:ELECTRON MICROSCOPY (3 Å)
Cite:Structure of the secretory immunoglobulin A core.
Science, 367, 2020
4HKJ
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BU of 4hkj by Molmil
Structure of Cowpox CPXV203 in complex with MHCI (H-2Kb)
Descriptor: Beta-2-microglobulin, CPXV203 protein, H-2 class I histocompatibility antigen, ...
Authors:McCoy IV, W.H, Fremont, D.H, Center for Structural Genomics of Infectious Diseases (CSGID)
Deposit date:2012-10-15
Release date:2012-11-14
Last modified:2023-12-06
Method:X-RAY DIFFRACTION (3 Å)
Cite:Structural Mechanism of ER Retrieval of MHC Class I by Cowpox.
Plos Biol., 10, 2012
4HK3
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BU of 4hk3 by Molmil
I2 Fab (unbound) from CH65-CH67 Lineage
Descriptor: I2 heavy chain, I2 light chain
Authors:Schmidt, A.G, Harrison, S.C.
Deposit date:2012-10-14
Release date:2012-11-21
Last modified:2017-11-15
Method:X-RAY DIFFRACTION (3 Å)
Cite:Preconfiguration of the antigen-binding site during affinity maturation of a broadly neutralizing influenza virus antibody.
Proc.Natl.Acad.Sci.USA, 110, 2013
1F11
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BU of 1f11 by Molmil
F124 FAB FRAGMENT FROM A MONOCLONAL ANTI-PRES2 ANTIBODY
Descriptor: F124 IMMUNOGLOBULIN (IGG1 HEAVY CHAIN), F124 IMMUNOGLOBULIN (KAPPA LIGHT CHAIN)
Authors:Saul, F.A, Vulliez-Le Normand, B, Passafiume, M, Riottot, M.M, Bentley, G.A.
Deposit date:2000-05-18
Release date:2000-08-30
Last modified:2023-08-09
Method:X-RAY DIFFRACTION (3 Å)
Cite:Structure of the Fab fragment from F124, a monoclonal antibody specific for hepatitis B surface antigen.
Acta Crystallogr.,Sect.D, 56, 2000
3CK0
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BU of 3ck0 by Molmil
ANTI-ANTI-IDIOTYPIC ANTIBODY AGAINST HUMAN ANGIOTENSIN II, COMPLEX WITH HUMAN ANGIOTENSIN II
Descriptor: PROTEIN (8-MER; HUMAN ANGIOTENSIN II), PROTEIN (IMMUNOGLOBULIN; HEAVY CHAIN), PROTEIN (IMMUNOGLOBULIN; LIGHT CHAIN)
Authors:Pan, Y.H, Amzel, L.M.
Deposit date:1999-06-14
Release date:2003-08-05
Last modified:2023-12-27
Method:X-RAY DIFFRACTION (3 Å)
Cite:Structures of Angiotensin II and a Phage-Display Selected Cyclic Peptide in Complex with Fab131: Making Angiotensin II Analogs
To be Published
2J6E
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BU of 2j6e by Molmil
Crystal Structure of an Autoimmune Complex between a Human IgM Rheumatoid Factor and IgG1 Fc reveals a Novel Fc Epitope and Evidence for Affinity Maturation
Descriptor: (4S)-2-METHYL-2,4-PENTANEDIOL, ACETATE ION, CACODYLATE ION, ...
Authors:Duquerroy, S, Stura, E.A, Bressanelli, S, Browne, H, Beale, D, Hamon, M, Casali, P, Vaney, M.C, Rey, F.A, Sutton, B.J, Taussig, M.J.
Deposit date:2006-09-28
Release date:2007-04-10
Last modified:2023-12-13
Method:X-RAY DIFFRACTION (3 Å)
Cite:Crystal structure of a human autoimmune complex between IgM rheumatoid factor RF61 and IgG1 Fc reveals a novel epitope and evidence for affinity maturation.
J.Mol.Biol., 368, 2007
4QHN
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BU of 4qhn by Molmil
I2 (unbound) from CH103 Lineage
Descriptor: I2 heavy chain, I2 light chain
Authors:Fera, D, Harrison, S.C.
Deposit date:2014-05-28
Release date:2014-06-11
Last modified:2023-09-20
Method:X-RAY DIFFRACTION (3 Å)
Cite:Affinity maturation in an HIV broadly neutralizing B-cell lineage through reorientation of variable domains.
Proc.Natl.Acad.Sci.USA, 111, 2014
4QRR
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BU of 4qrr by Molmil
Crystal Structure of HLA B*3501-IPS in complex with a Delta-Beta TCR, clone 12 TCR
Descriptor: Beta-2-microglobulin, HLA class I histocompatibility antigen, B-35 alpha chain, ...
Authors:Gras, S, Chabrol, E, Rossjohn, J.
Deposit date:2014-07-02
Release date:2014-12-10
Last modified:2023-09-20
Method:X-RAY DIFFRACTION (3 Å)
Cite:The molecular bases of delta / alpha beta T cell-mediated antigen recognition.
J.Exp.Med., 211, 2014
1FPT
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BU of 1fpt by Molmil
THREE-DIMENSIONAL STRUCTURE OF THE COMPLEX BETWEEN THE FAB FRAGMENT OF AN NEUTRALIZING ANTIBODY FOR TYPE 1 POLIOVIRUS AND ITS VIRAL EPITOPE
Descriptor: FAB FRAGMENT OF AN NEUTRALIZING ANTIBODY FOR TYPE 1 POLIOVIRUS, IGG2A-KAPPA C3 FAB (HEAVY CHAIN), IGG2A-KAPPA C3 FAB (LIGHT CHAIN)
Authors:Wien, M.W, Hogle, J.M.
Deposit date:1995-01-26
Release date:1995-03-31
Last modified:2024-06-05
Method:X-RAY DIFFRACTION (3 Å)
Cite:Structure of the complex between the Fab fragment of a neutralizing antibody for type 1 poliovirus and its viral epitope.
Nat.Struct.Biol., 2, 1995
1T83
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BU of 1t83 by Molmil
CRYSTAL STRUCTURE OF A HUMAN TYPE III FC GAMMA RECEPTOR IN COMPLEX WITH AN FC FRAGMENT OF IGG1 (ORTHORHOMBIC)
Descriptor: 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-2)-alpha-D-mannopyranose-(1-3)-[2-acetamido-2-deoxy-beta-D-glucopyranose-(1-2)-alpha-D-mannopyranose-(1-6)]beta-D-mannopyranose-(1-4)-2-acetamido-2-deoxy-alpha-D-glucopyranose-(1-4)-[beta-L-fucopyranose-(1-6)]2-acetamido-2-deoxy-beta-D-glucopyranose, DIBROMOMERCURY, IGG1, ...
Authors:Radaev, S, Motyka, S, Fridman, W.-H, Sautes-Fridman, C, Sun, P.D.
Deposit date:2004-05-11
Release date:2004-09-28
Last modified:2023-08-23
Method:X-RAY DIFFRACTION (3 Å)
Cite:The structure of a human type III Fcgamma receptor in complex with Fc
J.Biol.Chem., 276, 2001
2WBJ
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BU of 2wbj by Molmil
TCR complex
Descriptor: 2-acetamido-2-deoxy-beta-D-glucopyranose, HLA CLASS II HISTOCOMPATIBILITY ANTIGEN, DR ALPHA CHAIN, ...
Authors:Harkiolaki, M, Holmes, S.L, Svendsen, P, Gregersen, J.W, Jensen, L.T, McMahon, R, Friese, M.A, van Boxel, G, Etzensperger, R, Tzartos, J.S, Kranc, K, Sainsbury, S, Harlos, K, Mellins, E.D, Palace, J, Esiri, M.M, van der Merwe, P.A, Jones, E.Y, Fugger, L.
Deposit date:2009-03-02
Release date:2009-04-07
Last modified:2023-12-13
Method:X-RAY DIFFRACTION (3 Å)
Cite:T Cell-Mediated Autoimmune Disease due to Low-Affinity Crossreactivity to Common Microbial Peptides.
Immunity, 30, 2009
1E6J
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BU of 1e6j by Molmil
Crystal structure of HIV-1 capsid protein (p24) in complex with Fab13B5
Descriptor: CAPSID PROTEIN P24, IMMUNOGLOBULIN
Authors:Berthet-Colominas, C, Monaco, S, Novelli, A, Sibai, G, Mallet, F, Cusack, S.
Deposit date:2000-08-18
Release date:2000-11-27
Last modified:2023-12-13
Method:X-RAY DIFFRACTION (3 Å)
Cite:Mutual Conformational Adaptations in Antigen and Antibody Upon Complex Formation between an Fab and HIV-1 Capsid Protein P24
Structure, 8, 2000
8FJA
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BU of 8fja by Molmil
CryoEM structure of HLA-A2 MAGEA4 (230-239) in complex with REGN6972 Fab
Descriptor: Beta-2-microglobulin, MHC class I antigen, Melanoma-associated antigen 4 peptide, ...
Authors:Saotome, K, Franklin, M.C.
Deposit date:2022-12-19
Release date:2023-12-20
Method:ELECTRON MICROSCOPY (3 Å)
Cite:CryoEM structure of REGN6972 Fab in complex with HLA-A2 MAGEA4 (230-239)
To Be Published
6MJQ
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BU of 6mjq by Molmil
Crystal structure of the mCD1d/xxp (JJ295) /iNKTCR ternary complex
Descriptor: 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, Antigen-presenting glycoprotein CD1d1, ...
Authors:Zajonc, D.M, Bitra, A, Janssens, J.
Deposit date:2018-09-21
Release date:2019-01-09
Last modified:2023-10-11
Method:X-RAY DIFFRACTION (3 Å)
Cite:4"-O-Alkylated alpha-Galactosylceramide Analogues as iNKT-Cell Antigens: Synthetic, Biological, and Structural Studies.
ChemMedChem, 14, 2019
4P4R
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BU of 4p4r by Molmil
Structural Basis of Chronic Beryllium Disease: Bridging the Gap Between Allergic Hypersensitivity and Autoimmunity
Descriptor: 2-acetamido-2-deoxy-beta-D-glucopyranose, HLA class II histocompatibility antigen, DP alpha 1 chain, ...
Authors:Clayton, G.M, Crawford, F, Kappler, J.W.
Deposit date:2014-03-13
Release date:2014-07-16
Last modified:2023-12-27
Method:X-RAY DIFFRACTION (3 Å)
Cite:Structural basis of chronic beryllium disease: linking allergic hypersensitivity and autoimmunity.
Cell, 158, 2014

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数据于2024-07-10公开中

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