PDB: 92869 resultsInfo pagesStatus searchChemie searchBIRD

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1BT1	CATECHOL OXIDASE FROM IPOMOEA BATATAS (SWEET POTATOES) IN THE NATIVE CU(II)-CU(II) STATE Descriptor: CU-O-CU LINKAGE, PROTEIN (CATECHOL OXIDASE) Authors: Klabunde, T, Eicken, C, Sacchettini, J.C, Krebs, B. Deposit date: 1998-09-02 Release date: 1999-09-02 Last modified: 2023-12-27 Method: X-RAY DIFFRACTION (2.7 Å) Cite: Crystal structure of a plant catechol oxidase containing a dicopper center. Nat.Struct.Biol., 5, 1998
5HI3	Binding site elucidation and structure guided design of macrocyclic IL-17A antagonists Descriptor: CAT-2000 FAB heavy chain, CAT-2000 FAB light chain, Interleukin-17A, ... Authors: Liu, S. Deposit date: 2016-01-11 Release date: 2016-08-31 Last modified: 2023-09-27 Method: X-RAY DIFFRACTION (2.15 Å) Cite: Binding site elucidation and structure guided design of macrocyclic IL-17A antagonists. Sci Rep, 6, 2016
3ZJV	Ternary complex of E .coli leucyl-tRNA synthetase, tRNA(Leu) and the benzoxaborole AN3213 in the editing conformation Descriptor: LEUCINE--TRNA LIGASE, TRNALEU5 UAA ISOACCEPTOR Authors: Cusack, S, Palencia, A, Crepin, T, Hernandez, V, Akama, T, Baker, S.J, Bu, W, Feng, L, Freund, Y.R, Liu, L, Meewan, M, Mohan, M, Mao, W, Rock, F.L, Sexton, H, Sheoran, A, Zhang, Y, Zhang, Y, Zhou, Y, Nieman, J.A, Anugula, M.R, Keramane, E.M, Savariraj, K, Reddy, D.S, Sharma, R, Subedi, R, Singh, R, OLeary, A, Simon, N.L, DeMarsh, P.L, Mushtaq, S, Warner, M, Livermore, D.M, Alley, M.R.K, Plattner, J.J. Deposit date: 2013-01-18 Release date: 2013-04-17 Last modified: 2023-12-20 Method: X-RAY DIFFRACTION (2.31 Å) Cite: Discovery of a Novel Class of Boron-Based Antibacterials with Activity Against Gram-Negative Bacteria. Antimicrob.Agents Chemother., 57, 2013
5INP	Mouse Tdp2 reaction product (5'-phosphorylated DNA)-Mn2+ complex Descriptor: 4-(2-HYDROXYETHYL)-1-PIPERAZINE ETHANESULFONIC ACID, DNA (5'-D(P*CP*CP*GP*AP*AP*TP*TP*CP*G)-3'), MANGANESE (II) ION, ... Authors: Schellenberg, M.J, Williams, R.S. Deposit date: 2016-03-07 Release date: 2016-04-27 Last modified: 2023-09-27 Method: X-RAY DIFFRACTION (1.947 Å) Cite: Reversal of DNA damage induced Topoisomerase 2 DNA-protein crosslinks by Tdp2. Nucleic Acids Res., 44, 2016
2GGI	The mutant E149C-A182C of Deinococcus Radiodurans N-acylamino acid racemase Descriptor: N-acylamino acid racemase Authors: Wang, W.C, Chiu, W.C. Deposit date: 2006-03-24 Release date: 2006-04-11 Last modified: 2023-10-25 Method: X-RAY DIFFRACTION (2.2 Å) Cite: Structure-Stability-Activity Relationship in Covalently Cross-linked N-Carbamoyl d-Amino acid Amidohydrolase and N-Acylamino acid Racemase. J.Mol.Biol., 359, 2006
5I5T	X-RAY CRYSTAL STRUCTURE AT 2.31A RESOLUTION OF HUMAN MITOCHONDRIAL BRANCHED CHAIN AMINOTRANSFERASE (BCATM) COMPLEXED WITH A TETRAHYDROQUINOLINE COMPOUND AND AN INTERNAL ALDIMINE LINKED PLP COFACTOR. Descriptor: (3R)-3-methyl-1,2,3,4-tetrahydroquinoline-8-sulfonamide, 1,2-ETHANEDIOL, Branched-chain-amino-acid aminotransferase, ... Authors: Somers, D.O. Deposit date: 2016-02-15 Release date: 2016-03-23 Last modified: 2024-05-01 Method: X-RAY DIFFRACTION (2.31 Å) Cite: Structurally Diverse Mitochondrial Branched Chain Aminotransferase (BCATm) Leads with Varying Binding Modes Identified by Fragment Screening. J.Med.Chem., 59, 2016
5I5Y	X-RAY CRYSTAL STRUCTURE AT 1.81A RESOLUTION OF HUMAN MITOCHONDRIAL BRANCHED CHAIN AMINOTRANSFERASE (BCATM) COMPLEXED WITH AN ARYL ACETATE COMPOUND AND AN INTERNAL ALDIMINE LINKED PLP COFACTOR. Descriptor: 1,2-ETHANEDIOL, Branched-chain-amino-acid aminotransferase, mitochondrial, ... Authors: Somers, D.O. Deposit date: 2016-02-15 Release date: 2016-03-23 Last modified: 2024-05-01 Method: X-RAY DIFFRACTION (1.81 Å) Cite: Structurally Diverse Mitochondrial Branched Chain Aminotransferase (BCATm) Leads with Varying Binding Modes Identified by Fragment Screening. J.Med.Chem., 59, 2016
6H29	HUMAN CARBONIC ANHYDRASE II IN COMPLEX WITH BENZYL CARBAMATE Descriptor: (phenylmethyl) carbamate, Carbonic anhydrase 2, ZINC ION Authors: Alterio, V, De Simone, G. Deposit date: 2018-07-13 Release date: 2018-09-05 Last modified: 2024-01-17 Method: X-RAY DIFFRACTION (1.46 Å) Cite: Inhibition of carbonic anhydrases by a substrate analog: benzyl carbamate directly coordinates the catalytic zinc ion mimicking bicarbonate binding. Chem. Commun. (Camb.), 54, 2018
3IN4	Bace1 with Compound 38 Descriptor: (5S)-2-amino-5-(2,6-diethylpyridin-4-yl)-3-methyl-5-(3-pyrimidin-5-ylphenyl)-3,5-dihydro-4H-imidazol-4-one, Beta-secretase 1 Authors: Olland, A.M. Deposit date: 2009-08-11 Release date: 2010-01-19 Last modified: 2011-07-13 Method: X-RAY DIFFRACTION (2.3 Å) Cite: Di-substituted pyridinyl aminohydantoins as potent and highly selective human beta-secretase (BACE1) inhibitors. Bioorg.Med.Chem., 18, 2010
2FLH	Crystal structure of cytokinin-specific binding protein from mung bean in complex with cytokinin Descriptor: (2E)-2-methyl-4-(9H-purin-6-ylamino)but-2-en-1-ol, SODIUM ION, cytokinin-specific binding protein Authors: Pasternak, O, Bujacz, G.D, Sikorski, M.M, Jaskolski, M. Deposit date: 2006-01-06 Release date: 2006-11-21 Last modified: 2024-02-14 Method: X-RAY DIFFRACTION (1.2 Å) Cite: Crystal Structure of Vigna radiata Cytokinin-Specific Binding Protein in Complex with Zeatin. Plant Cell, 18, 2006
3IN3	Bace1 with Compound 30 Descriptor: (5S)-2-amino-3-methyl-5-pyridin-4-yl-5-(3-pyridin-3-ylphenyl)-3,5-dihydro-4H-imidazol-4-one, Beta-secretase 1 Authors: Olland, A.M. Deposit date: 2009-08-11 Release date: 2010-01-19 Last modified: 2011-07-13 Method: X-RAY DIFFRACTION (2 Å) Cite: Di-substituted pyridinyl aminohydantoins as potent and highly selective human beta-secretase (BACE1) inhibitors. Bioorg.Med.Chem., 18, 2010
5W59	Crystal structure of a monomeric human FGF9 in complex with the ectodomain of human FGFR1c Descriptor: Fibroblast growth factor 9, Fibroblast growth factor receptor 1, SULFATE ION Authors: Mohammadi, M, Ma, J, Liu, Y. Deposit date: 2017-06-14 Release date: 2017-08-16 Last modified: 2023-10-04 Method: X-RAY DIFFRACTION (2.498 Å) Cite: Regulation of Receptor Binding Specificity of FGF9 by an Autoinhibitory Homodimerization. Structure, 25, 2017
1HQL	The xenograft antigen in complex with the B4 isolectin of Griffonia simplicifolia lectin-1 Descriptor: 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, CALCIUM ION, LECTIN, ... Authors: Tempel, W, Lipscomb, L.A, Rose, J.P, Woods, R.J. Deposit date: 2000-12-18 Release date: 2002-01-16 Last modified: 2020-07-29 Method: X-RAY DIFFRACTION (2.2 Å) Cite: The xenograft antigen bound to Griffonia simplicifolia lectin 1-B(4). X-ray crystal structure of the complex and molecular dynamics characterization of the binding site. J.Biol.Chem., 277, 2002
2GGJ	The mutant Y218C of Deinococcus Radiodurans N-acylamino acid racemase Descriptor: N-acylamino acid racemase Authors: Wang, W.C, Chiu, W.C. Deposit date: 2006-03-24 Release date: 2006-04-11 Last modified: 2023-10-25 Method: X-RAY DIFFRACTION (2.5 Å) Cite: Structure-Stability-Activity Relationship in Covalently Cross-linked N-Carbamoyl d-Amino acid Amidohydrolase and N-Acylamino acid Racemase. J.Mol.Biol., 359, 2006
1JJC	Crystal structure at 2.6A resolution of phenylalanyl-tRNA synthetase complexed with phenylalanyl-adenylate in the presence of manganese Descriptor: ADENOSINE-5'-[PHENYLALANINYL-PHOSPHATE], MANGANESE (II) ION, PHENYLALANYL-TRNA SYNTHETASE ALPHA CHAIN, ... Authors: Safro, M.G, Fishman, R, Moor, N, Ankilova, V. Deposit date: 2001-07-04 Release date: 2001-11-02 Last modified: 2023-08-16 Method: X-RAY DIFFRACTION (2.6 Å) Cite: Structure at 2.6 A resolution of phenylalanyl-tRNA synthetase complexed with phenylalanyl-adenylate in the presence of manganese. Acta Crystallogr.,Sect.D, 57, 2001
1JU9	HORSE LIVER ALCOHOL DEHYDROGENASE VAL292SER MUTANT Descriptor: ALCOHOL DEHYDROGENASE, NICOTINAMIDE-ADENINE-DINUCLEOTIDE, ZINC ION Authors: Rubach, J.K, Ramaswamy, S, Plapp, B.V. Deposit date: 2001-08-24 Release date: 2001-09-19 Last modified: 2023-08-16 Method: X-RAY DIFFRACTION (2 Å) Cite: Contributions of valine-292 in the nicotinamide binding site of liver alcohol dehydrogenase and dynamics to catalysis. Biochemistry, 40, 2001
1AT6	HEN EGG WHITE LYSOZYME WITH A ISOASPARTATE RESIDUE Descriptor: 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, LYSOZYME Authors: Noguchi, S, Miyawaki, K, Satow, Y. Deposit date: 1997-08-19 Release date: 1998-02-25 Last modified: 2023-08-02 Method: X-RAY DIFFRACTION (1.8 Å) Cite: Succinimide and isoaspartate residues in the crystal structures of hen egg-white lysozyme complexed with tri-N-acetylchitotriose. J.Mol.Biol., 278, 1998
3IVA	Structure of the B12-dependent Methionine Synthase (MetH) C-teminal half with AdoHcy bound Descriptor: COBALAMIN, Methionine synthase, NITRATE ION, ... Authors: Pattridge, K.A, Koutmos, M, Smith, J.L. Deposit date: 2009-08-31 Release date: 2009-11-24 Last modified: 2023-09-06 Method: X-RAY DIFFRACTION (2.7 Å) Cite: Insights into the reactivation of cobalamin-dependent methionine synthase. Proc.Natl.Acad.Sci.USA, 106, 2009
4CQN	Crystal structure of the E.coli LeuRS-tRNA complex with the non- cognate isoleucyl adenylate analogue Descriptor: ESCHERICHIA COLI TRNA-LEU UAA ISOACCEPTOR, LEUCINE--TRNA LIGASE, MAGNESIUM ION, ... Authors: Palencia, A, Cusack, S, Cvetesic, N, Haslaz, I, Gruic-Sovulj, I. Deposit date: 2014-02-20 Release date: 2014-07-02 Last modified: 2023-12-20 Method: X-RAY DIFFRACTION (2.5 Å) Cite: The Physiological Target for Leurs Translational Quality Control is Norvaline Embo J., 33, 2014
3WSY	SorLA Vps10p domain in complex with its own propeptide fragment Descriptor: 2-acetamido-2-deoxy-beta-D-glucopyranose, Sortilin-related receptor, peptide from Sortilin-related receptor Authors: Kitago, Y, Nakata, Z, Nagae, M, Nogi, T, Takagi, J. Deposit date: 2014-03-30 Release date: 2015-02-04 Last modified: 2023-11-08 Method: X-RAY DIFFRACTION (3.11 Å) Cite: Structural basis for amyloidogenic peptide recognition by sorLA. Nat.Struct.Mol.Biol., 22, 2015
1XWH	NMR structure of the first phd finger of autoimmune regulator protein (AIRE1): insights into apeced Descriptor: Autoimmune regulator, ZINC ION Authors: Bottomley, M.J, Stier, G, Krasotkina, J, Legube, G, Simon, B, Akhtar, A, Sattler, M, Musco, G. Deposit date: 2004-11-01 Release date: 2005-01-25 Last modified: 2024-05-29 Method: SOLUTION NMR Cite: NMR structure of the first PHD finger of autoimmune regulator protein (AIRE1). Insights into autoimmune polyendocrinopathy-candidiasis-ectodermal dystrophy (APECED) disease J.Biol.Chem., 280, 2005
2DVN	Structure of PH1917 protein with the complex of IMP from Pyrococcus horikoshii Descriptor: GLYCEROL, Hypothetical protein PH1917, INOSINIC ACID, ... Authors: Lokanath, N.K, RIKEN Structural Genomics/Proteomics Initiative (RSGI) Deposit date: 2006-07-31 Release date: 2007-09-04 Last modified: 2023-10-25 Method: X-RAY DIFFRACTION (1.6 Å) Cite: Structures of dimeric nonstandard nucleotide triphosphate pyrophosphatase from Pyrococcus horikoshii OT3: functional significance of interprotomer conformational changes J.Mol.Biol., 375, 2008
5IBI	Crystal structure Mycobacterium tuberculosis CYP121 in complex with inhibitor fragment 26a Descriptor: 4,4'-(5-{[(4-hydroxyphenyl)methyl]amino}-1H-pyrazole-3,4-diyl)diphenol, Cytochrome P450 121 CYP121, PROTOPORPHYRIN IX CONTAINING FE, ... Authors: Levy, C. Deposit date: 2016-02-22 Release date: 2016-04-06 Last modified: 2024-05-01 Method: X-RAY DIFFRACTION (2.2 Å) Cite: Fragment-Based Approaches to the Development of Mycobacterium tuberculosis CYP121 Inhibitors. J.Med.Chem., 59, 2016
5IBE	Crystal structure Mycobacterium tuberculosis CYP121 in complex with inhibitor fragment 25a Descriptor: 2-(N-MORPHOLINO)-ETHANESULFONIC ACID, 4-[5-amino-4-(3'-amino[1,1'-biphenyl]-3-yl)-1H-pyrazol-3-yl]phenol, Mycocyclosin synthase, ... Authors: Levy, C. Deposit date: 2016-02-22 Release date: 2016-04-06 Last modified: 2024-05-01 Method: X-RAY DIFFRACTION (1.624 Å) Cite: Fragment-Based Approaches to the Development of Mycobacterium tuberculosis CYP121 Inhibitors. J.Med.Chem., 59, 2016
3KJ1	Mcl-1 in complex with Bim BH3 mutant I2dA Descriptor: ACETATE ION, Bcl-2-like protein 11, CHLORIDE ION, ... Authors: Fire, E, Grant, R.A, Keating, A.E. Deposit date: 2009-11-02 Release date: 2010-02-16 Last modified: 2023-12-27 Method: X-RAY DIFFRACTION (1.945 Å) Cite: Mcl-1-Bim complexes accommodate surprising point mutations via minor structural changes. Protein Sci., 19, 2010

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