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4M4M
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BU of 4m4m by Molmil
The structure of Ni T6 bovine insulin
Descriptor: Insulin, NICKEL (II) ION
Authors:Frankaer, C.G, Harris, P, Stahl, K.
Deposit date:2013-08-07
Release date:2014-01-15
Last modified:2024-10-09
Method:X-RAY DIFFRACTION (1.5 Å)
Cite:Towards accurate structural characterization of metal centres in protein crystals: the structures of Ni and Cu T6 bovine insulin derivatives.
Acta Crystallogr.,Sect.D, 70, 2014
1LVA
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BU of 1lva by Molmil
Crystal structure of a C-terminal fragment of Moorella thermoacetica elongation factor SelB
Descriptor: SULFATE ION, Selenocysteine-specific elongation factor, YTTRIUM ION
Authors:Selmer, M, Su, X.-D.
Deposit date:2002-05-28
Release date:2002-08-21
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (2.12 Å)
Cite:Crystal structure of an mRNA-binding fragment of Moorella thermoacetica elongation factor SelB.
EMBO J., 21, 2002
7AD1
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BU of 7ad1 by Molmil
Cryo-EM structure of a prefusion stabilized SARS-CoV-2 Spike (D614N, R682S, R685G, A892P, A942P and V987P)(One up trimer)
Descriptor: 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, Spike glycoprotein,Envelope glycoprotein,Spike glycoprotein,Envelope glycoprotein,SARS-CoV-2 S protein
Authors:Rutten, L, Renault, L.L.R, Juraszek, J, Langedijk, J.P.M.
Deposit date:2020-09-14
Release date:2020-11-04
Last modified:2024-10-09
Method:ELECTRON MICROSCOPY (2.92 Å)
Cite:Stabilizing the closed SARS-CoV-2 spike trimer.
Nat Commun, 12, 2021
9F43
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BU of 9f43 by Molmil
cryo-EM structure of human LST2 bound to human mTOR complex 1, focused on RAPTOR
Descriptor: Lateral signaling target protein 2 homolog, Regulatory-associated protein of mTOR
Authors:Craigie, L.M, Maier, T.
Deposit date:2024-04-26
Release date:2024-08-14
Last modified:2024-08-28
Method:ELECTRON MICROSCOPY (3.49 Å)
Cite:mTORC1 phosphorylates and stabilizes LST2 to negatively regulate EGFR.
Proc.Natl.Acad.Sci.USA, 121, 2024
4X3H
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BU of 4x3h by Molmil
CRYSTAL STRUCTURE OF ARC N-LOBE COMPLEXED WITH STARGAZIN PEPTIDE
Descriptor: Activity-regulated cytoskeleton-associated protein, VOLTAGE-DEPENDENT CALCIUM CHANNEL GAMMA-2 SUBUNIT
Authors:zhang, W, ward, m, leahy, d, worley, p.
Deposit date:2014-11-30
Release date:2015-06-03
Last modified:2024-02-28
Method:X-RAY DIFFRACTION (2.401 Å)
Cite:Structural basis of arc binding to synaptic proteins: implications for cognitive disease.
Neuron, 86, 2015
4MD2
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BU of 4md2 by Molmil
Ground state of bacteriorhodopsin from Halobacterium salinarum
Descriptor: (6E,10E,14E,18E)-2,6,10,15,19,23-hexamethyltetracosa-2,6,10,14,18,22-hexaene, 2,3-DI-PHYTANYL-GLYCEROL, Bacteriorhodopsin, ...
Authors:Borshchevskiy, V, Erofeev, I, Round, E, Weik, M, Ishchenko, A, Gushchin, I, Mishin, A, Bueldt, G, Gordeliy, V.
Deposit date:2013-08-22
Release date:2014-10-08
Last modified:2023-09-20
Method:X-RAY DIFFRACTION (1.73 Å)
Cite:Low-dose X-ray radiation induces structural alterations in proteins.
Acta Crystallogr.,Sect.D, 70, 2014
9BAF
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BU of 9baf by Molmil
Solution NMR structure of conofurin-Delta
Descriptor: Alpha-conotoxin LvIA
Authors:Harvey, P.J, Craik, D.J, Hone, A.J, McIntosh, J.M.
Deposit date:2024-04-04
Release date:2024-07-03
Method:SOLUTION NMR
Cite:Design, Synthesis, and Structure-Activity Relationships of Novel Peptide Derivatives of the Severe Acute Respiratory Syndrome-Coronavirus-2 Spike-Protein that Potently Inhibit Nicotinic Acetylcholine Receptors.
J.Med.Chem., 67, 2024
9BB4
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BU of 9bb4 by Molmil
Backbone Modification in the GA Module of Protein PAB: beta3-residues at positions 23 and 26
Descriptor: Peptostreptococcal albumin-binding protein
Authors:Lin, Y, Horne, W.S.
Deposit date:2024-04-05
Release date:2024-06-05
Last modified:2024-08-21
Method:SOLUTION NMR
Cite:Backbone Modification in a Protein Hydrophobic Core.
Chemistry, 30, 2024
6OT3
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BU of 6ot3 by Molmil
RF2 accommodated state bound Release complex 70S at 24 ms
Descriptor: 16S ribosomal RNA, 23S ribosomal RNA, 30S ribosomal protein S10, ...
Authors:Fu, Z, Indrisiunaite, G, Kaledhonkar, S, Shah, B, Sun, M, Chen, B, Grassucci, R.A, Ehrenberg, M, Frank, J.
Deposit date:2019-05-02
Release date:2019-06-19
Last modified:2019-12-18
Method:ELECTRON MICROSCOPY (3.9 Å)
Cite:The structural basis for release-factor activation during translation termination revealed by time-resolved cryogenic electron microscopy.
Nat Commun, 10, 2019
9F45
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BU of 9f45 by Molmil
cryo-EM structure of human LST2 bound to human mTOR complex 1
Descriptor: INOSITOL HEXAKISPHOSPHATE, Lateral signaling target protein 2 homolog, Regulatory-associated protein of mTOR, ...
Authors:Craigie, L.M, Maier, T.
Deposit date:2024-04-26
Release date:2024-08-14
Last modified:2024-08-28
Method:ELECTRON MICROSCOPY (3.74 Å)
Cite:mTORC1 phosphorylates and stabilizes LST2 to negatively regulate EGFR.
Proc.Natl.Acad.Sci.USA, 121, 2024
9CIH
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BU of 9cih by Molmil
Crystal structure of human polymerase eta with incoming dCMPnPP nucleotide across O4-methyl threofuranosyl thymidine in DNA template at extension stage
Descriptor: 2'-deoxy-5'-O-[(R)-hydroxy{[(R)-hydroxy(phosphonooxy)phosphoryl]amino}phosphoryl]cytidine, DNA (5'-D(*AP*GP*CP*GP*TP*CP*AP*A)-3'), DNA (5'-D(*CP*AP*TP*GP*(A1A0L)P*TP*GP*AP*CP*GP*CP*T)-3'), ...
Authors:Tomar, R, Stone, M.P, Egli, M.
Deposit date:2024-07-03
Release date:2024-09-18
Last modified:2024-09-25
Method:X-RAY DIFFRACTION (2.15 Å)
Cite:DNA Replication across alpha-l-(3'-2')-Threofuranosyl Nucleotides Mediated by Human DNA Polymerase eta.
Biochemistry, 2024
1LWJ
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BU of 1lwj by Molmil
CRYSTAL STRUCTURE OF T. MARITIMA 4-ALPHA-GLUCANOTRANSFERASE/ACARBOSE COMPLEX
Descriptor: 4-ALPHA-GLUCANOTRANSFERASE, CALCIUM ION, MODIFIED ACARBOSE PENTASACCHARIDE
Authors:Roujeinikova, A, Raasch, C, Sedelnikova, S, Liebl, W, Rice, D.W.
Deposit date:2002-05-31
Release date:2002-08-14
Last modified:2024-02-14
Method:X-RAY DIFFRACTION (2.5 Å)
Cite:CRYSTAL STRUCTURE OF THERMOTOGA MARITIMA 4-ALPHA-GLUCANOTRANSFERASE AND ITS ACARBOSE COMPLEX: IMPLICATIONS FOR SUBSTRATE SPECIFICITY AND CATALYSIS
J.Mol.Biol., 321, 2002
9ATW
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BU of 9atw by Molmil
Structure of biofilm-forming functional amyloid PSMa1 from Staphylococcus aureus
Descriptor: Phenol-soluble modulin alpha 1 peptide
Authors:Hansen, K.H, Byeon, C.H, Liu, Q, Drace, T, Boesen, T, Conway, J.F, Andreasen, M, Akbey, U.
Deposit date:2024-02-27
Release date:2024-08-07
Last modified:2024-08-21
Method:ELECTRON MICROSCOPY (3.5 Å)
Cite:Structure of biofilm-forming functional amyloid PSM alpha 1 from Staphylococcus aureus.
Proc.Natl.Acad.Sci.USA, 121, 2024
2FFF
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BU of 2fff by Molmil
Open Form of a Class A Transpeptidase Domain
Descriptor: NICKEL (II) ION, penicillin-binding protein 1B
Authors:Lovering, A.L, Strynadka, N.C.J.
Deposit date:2005-12-19
Release date:2006-06-20
Last modified:2023-08-30
Method:X-RAY DIFFRACTION (2.23 Å)
Cite:Structural analysis of an "open" form of PBP1B from Streptococcus pneumoniae.
Protein Sci., 15, 2006
2QO5
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BU of 2qo5 by Molmil
Crystal structure of the cysteine 91 threonine mutant of zebrafish liver bile acid-binding protein complexed with cholic acid
Descriptor: CHOLIC ACID, Liver-basic fatty acid binding protein
Authors:Capaldi, S, Saccomani, G, Perduca, M, Monaco, H.L.
Deposit date:2007-07-20
Release date:2007-07-31
Last modified:2023-08-30
Method:X-RAY DIFFRACTION (1.5 Å)
Cite:A Single Amino Acid Mutation in Zebrafish (Danio rerio) Liver Bile Acid-binding Protein Can Change the Stoichiometry of Ligand Binding.
J.Biol.Chem., 282, 2007
9B9G
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BU of 9b9g by Molmil
Structure of the PI4KA complex bound to Calcineurin
Descriptor: CALCIUM ION, Calcineurin subunit B type 1, Hyccin, ...
Authors:Shaw, A.L, Suresh, S, Yip, C.K, Burke, J.E.
Deposit date:2024-04-02
Release date:2024-09-11
Method:ELECTRON MICROSCOPY (3.5 Å)
Cite:Structure of calcineurin bound to PI4KA reveals dual interface in both PI4KA and FAM126A.
Structure, 2024
6OYA
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BU of 6oya by Molmil
Structure of the Rhodopsin-Transducin-Nanobody Complex
Descriptor: Camelid antibody VHH fragment, Gt-alpha/Gi1-alpha chimera, Guanine nucleotide-binding protein G(I)/G(S)/G(T) subunit beta-1, ...
Authors:Gao, Y, Hu, H, Ramachandran, S, Erickson, J.W, Cerione, R.A, Skiniotis, G.
Deposit date:2019-05-14
Release date:2019-07-24
Last modified:2019-12-04
Method:ELECTRON MICROSCOPY (3.3 Å)
Cite:Structures of the Rhodopsin-Transducin Complex: Insights into G-Protein Activation.
Mol.Cell, 75, 2019
1LYY
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BU of 1lyy by Molmil
AMYLOIDOGENIC VARIANT (ASP67HIS) OF HUMAN LYSOZYME
Descriptor: LYSOZYME
Authors:Sunde, M, Blake, C.C.F.
Deposit date:1997-01-16
Release date:1997-04-01
Last modified:2024-04-03
Method:X-RAY DIFFRACTION (1.8 Å)
Cite:Instability, unfolding and aggregation of human lysozyme variants underlying amyloid fibrillogenesis.
Nature, 385, 1997
9BB3
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BU of 9bb3 by Molmil
Backbone Modification in the GA Module of Protein PAB: beta3-residues at positions 22 and 26
Descriptor: Peptostreptococcal albumin-binding protein
Authors:Lin, Y, Horne, W.S.
Deposit date:2024-04-05
Release date:2024-06-05
Last modified:2024-08-21
Method:SOLUTION NMR
Cite:Backbone Modification in a Protein Hydrophobic Core.
Chemistry, 30, 2024
5WXE
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BU of 5wxe by Molmil
Highly disulfide-constrained antifeedant jasmintides from Jasminum sambac flowers
Descriptor: jasmintide js3
Authors:Kumari, G, Wong, K.H, Serra, A, Shin, J, Yoon, H.S, Sze, S.K, James, P.T.
Deposit date:2017-01-07
Release date:2018-01-17
Last modified:2023-06-14
Method:SOLUTION NMR
Cite:Highly disulfide-constrained antifeedant jasmintides from Jasminum sambac flowers
To Be Published
1M63
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BU of 1m63 by Molmil
Crystal structure of calcineurin-cyclophilin-cyclosporin shows common but distinct recognition of immunophilin-drug complexes
Descriptor: CALCINEURIN B SUBUNIT ISOFORM 1, CALCIUM ION, CYCLOSPORIN A, ...
Authors:Huai, Q, Kim, H.-Y, Liu, Y, Zhao, Y, Mondragon, A, Liu, J.O, Ke, H.
Deposit date:2002-07-12
Release date:2002-09-25
Last modified:2024-04-03
Method:X-RAY DIFFRACTION (2.8 Å)
Cite:Crystal Structure of Calcineurin-Cyclophilin-Cyclosporin Shows Common But Distinct Recognition of Immunophilin-Drug Complexes
Proc.Natl.Acad.Sci.USA, 99, 2002
1LZO
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BU of 1lzo by Molmil
Plasmodium Falciparum Triosephosphate Isomerase-Phosphoglycolate Complex
Descriptor: 2-PHOSPHOGLYCOLIC ACID, Triosephosphate Isomerase
Authors:Parthasarathy, S, Balaram, H, Balaram, P, Murthy, M.R.
Deposit date:2002-06-11
Release date:2003-01-28
Last modified:2024-02-14
Method:X-RAY DIFFRACTION (2.8 Å)
Cite:Structure of the Plasmodium falciparum triosephosphate isomerase-phosphoglycolate complex in two crystal forms: characterization of catalytic loop open and closed conformations in the ligand-bound state
Biochemistry, 41, 2002
5WQZ
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BU of 5wqz by Molmil
Solution structure of a histone binding domain
Descriptor: Putative uncharacterized protein
Authors:Mi, J.
Deposit date:2016-11-29
Release date:2017-01-25
Last modified:2024-05-15
Method:SOLUTION NMR
Cite:Solution Structure Of A Histone Binding Domain
To Be Published
6OD5
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BU of 6od5 by Molmil
Human TCF4 C-terminal bHLH domain in Complex with 12-bp Oligonucleotide Containing E-box Sequence with 5-carboxylcytosines
Descriptor: 1,2-ETHANEDIOL, CHLORIDE ION, DNA (5'-D(*AP*(1CC)P*GP*CP*AP*CP*GP*TP*GP*(1CC)P*G)-3'), ...
Authors:Horton, J.R, Cheng, X, Yang, J.
Deposit date:2019-03-25
Release date:2019-05-29
Last modified:2023-10-11
Method:X-RAY DIFFRACTION (2.05 Å)
Cite:Structural basis for preferential binding of human TCF4 to DNA containing 5-carboxylcytosine.
Nucleic Acids Res., 47, 2019
9BB1
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BU of 9bb1 by Molmil
Backbone Modification in the GA Module of Protein PAB: Wild-type Sequence
Descriptor: Peptostreptococcal albumin-binding protein
Authors:Lin, Y, Horne, W.S.
Deposit date:2024-04-05
Release date:2024-06-05
Last modified:2024-08-21
Method:SOLUTION NMR
Cite:Backbone Modification in a Protein Hydrophobic Core.
Chemistry, 30, 2024

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数据于2024-10-09公开中

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