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5UGJ
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BU of 5ugj by Molmil
Crystal structure of HTPA Reductase from neisseria meningitidis
Descriptor: 4-hydroxy-tetrahydrodipicolinate reductase
Authors:Keown, J.K, Richards, E.W, Pearce, F.G, Goldstone, D.C.
Deposit date:2017-01-08
Release date:2017-12-13
Last modified:2023-10-04
Method:X-RAY DIFFRACTION (2.7 Å)
Cite:Plant DHDPR forms a dimer with unique secondary structure features that preclude higher-order assembly.
Biochem. J., 475, 2018
1S9R
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BU of 1s9r by Molmil
CRYSTAL STRUCTURE OF ARGININE DEIMINASE COVALENTLY LINKED WITH A REACTION INTERMEDIATE
Descriptor: 2-AMINO-2-HYDROXYMETHYL-PROPANE-1,3-DIOL, ARGININE, Arginine deiminase, ...
Authors:Das, K, Buttler, G.H, Kwiatkowski, V, Clark Jr, A.D, Yadav, P, Arnold, E.
Deposit date:2004-02-05
Release date:2004-04-13
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (1.6 Å)
Cite:Crystal Structures of Arginine Deiminase with Covalent Reaction Intermediates: Implications for Catalytic Mechanism
Structure, 12, 2004
8GEA
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BU of 8gea by Molmil
CryoEM structure of beta-2-adrenergic receptor in complex with nucleotide-free Gs heterotrimer (#11 of 20)
Descriptor: (5R,6R)-6-(methylamino)-5,6,7,8-tetrahydronaphthalene-1,2,5-triol, Beta-2 adrenergic receptor, Guanine nucleotide-binding protein G(I)/G(S)/G(O) subunit gamma-2, ...
Authors:Papasergi-Scott, M.M, Skiniotis, G.
Deposit date:2023-03-06
Release date:2024-03-06
Last modified:2024-06-05
Method:ELECTRON MICROSCOPY (3.5 Å)
Cite:Time-resolved cryo-EM of G-protein activation by a GPCR.
Nature, 629, 2024
8GEJ
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BU of 8gej by Molmil
CryoEM structure of beta-2-adrenergic receptor in complex with nucleotide-free Gs heterotrimer (#20 of 20)
Descriptor: (5R,6R)-6-(methylamino)-5,6,7,8-tetrahydronaphthalene-1,2,5-triol, Beta-2 adrenergic receptor, Guanine nucleotide-binding protein G(I)/G(S)/G(O) subunit gamma-2, ...
Authors:Papasergi-Scott, M.M, Skiniotis, G.
Deposit date:2023-03-06
Release date:2024-03-06
Last modified:2024-06-05
Method:ELECTRON MICROSCOPY (4.2 Å)
Cite:Time-resolved cryo-EM of G-protein activation by a GPCR.
Nature, 629, 2024
8OQ9
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BU of 8oq9 by Molmil
Crystal structure of the titin domain Fn3-56
Descriptor: CHLORIDE ION, Titin, ZINC ION
Authors:Rees, M, Gautel, M.
Deposit date:2023-04-11
Release date:2023-08-23
Last modified:2023-08-30
Method:X-RAY DIFFRACTION (1.65 Å)
Cite:Structure determination and analysis of titin A-band fibronectin type III domains provides insights for disease-linked variants and protein oligomerisation.
J.Struct.Biol., 215, 2023
8GEF
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BU of 8gef by Molmil
CryoEM structure of beta-2-adrenergic receptor in complex with nucleotide-free Gs heterotrimer (#16 of 20)
Descriptor: (5R,6R)-6-(methylamino)-5,6,7,8-tetrahydronaphthalene-1,2,5-triol, Beta-2 adrenergic receptor, Guanine nucleotide-binding protein G(I)/G(S)/G(O) subunit gamma-2, ...
Authors:Papasergi-Scott, M.M, Skiniotis, G.
Deposit date:2023-03-06
Release date:2024-03-06
Last modified:2024-06-05
Method:ELECTRON MICROSCOPY (3.8 Å)
Cite:Time-resolved cryo-EM of G-protein activation by a GPCR.
Nature, 629, 2024
1C98
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BU of 1c98 by Molmil
SOLUTION STRUCTURE OF NEUROMEDIN B
Descriptor: NEUROMEDIN B
Authors:Lee, S, Kim, Y.
Deposit date:1999-08-01
Release date:1999-08-11
Last modified:2022-02-16
Method:SOLUTION NMR
Cite:Solution structure of neuromedin B by (1)H nuclear magnetic resonance spectroscopy.
FEBS Lett., 460, 1999
8GG2
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BU of 8gg2 by Molmil
CryoEM structure of beta-2-adrenergic receptor in complex with GTP-bound Gs heterotrimer (transition intermediate #8 of 20)
Descriptor: (5R,6R)-6-(methylamino)-5,6,7,8-tetrahydronaphthalene-1,2,5-triol, Beta-2 adrenergic receptor, GUANOSINE-5'-TRIPHOSPHATE, ...
Authors:Papasergi-Scott, M.M, Skiniotis, G.
Deposit date:2023-03-08
Release date:2024-03-06
Last modified:2024-06-12
Method:ELECTRON MICROSCOPY (3 Å)
Cite:Time-resolved cryo-EM of G-protein activation by a GPCR.
Nature, 629, 2024
8GG7
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BU of 8gg7 by Molmil
CryoEM structure of beta-2-adrenergic receptor in complex with GTP-bound Gs heterotrimer (transition intermediate #13 of 20)
Descriptor: (5R,6R)-6-(methylamino)-5,6,7,8-tetrahydronaphthalene-1,2,5-triol, Beta-2 adrenergic receptor, GUANOSINE-5'-TRIPHOSPHATE, ...
Authors:Papasergi-Scott, M.M, Skiniotis, G.
Deposit date:2023-03-08
Release date:2024-03-06
Last modified:2024-06-12
Method:ELECTRON MICROSCOPY (3.3 Å)
Cite:Time-resolved cryo-EM of G-protein activation by a GPCR.
Nature, 629, 2024
5N11
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BU of 5n11 by Molmil
Crystal structure of Human beta1-coronavirus OC43 NL/A/2005 Hemagglutinin-Esterase
Descriptor: 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, ACETIC ACID, ...
Authors:Bakkers, M.J.G, Feitsma, L.J, de Groot, R.J, Huizinga, E.G.
Deposit date:2017-02-04
Release date:2017-03-22
Last modified:2024-01-17
Method:X-RAY DIFFRACTION (2.45 Å)
Cite:Betacoronavirus Adaptation to Humans Involved Progressive Loss of Hemagglutinin-Esterase Lectin Activity.
Cell Host Microbe, 21, 2017
5UHU
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BU of 5uhu by Molmil
Solution conformation of cytochrome P450 MycG with mycinamicin IV bound
Descriptor: MYCINAMICIN IV, Mycinamicin IV hydroxylase/epoxidase, PROTOPORPHYRIN IX CONTAINING FE
Authors:Pochapsky, T.C, Tietz, D.R.
Deposit date:2017-01-12
Release date:2017-08-23
Last modified:2024-05-01
Method:SOLUTION NMR
Cite:Solution Conformations and Dynamics of Substrate-Bound Cytochrome P450 MycG.
Biochemistry, 56, 2017
8AFZ
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BU of 8afz by Molmil
Architecture of the ESCPE-1 membrane coat
Descriptor: Cation-independent mannose-6-phosphate receptor, Sorting nexin-1, Sorting nexin-5
Authors:Lopez-Robles, C, Scaramuzza, S, Astorga-Simon, E, Ishida, M, Williamsom, C.D, Banos-Mateos, S, Gil-Carton, D, Romero, M, Vidaurrazaga, A, Fernandez-Recio, J, Rojas, A.L, Bonifacino, J.S, Castano-Diez, D, Hierro, A.
Deposit date:2022-07-18
Release date:2023-06-21
Last modified:2023-07-26
Method:ELECTRON MICROSCOPY (10 Å)
Cite:Architecture of the ESCPE-1 membrane coat.
Nat.Struct.Mol.Biol., 30, 2023
8GGE
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BU of 8gge by Molmil
CryoEM structure of beta-2-adrenergic receptor in complex with GTP-bound Gs heterotrimer (transition intermediate #19 of 20)
Descriptor: (5R,6R)-6-(methylamino)-5,6,7,8-tetrahydronaphthalene-1,2,5-triol, Beta-2 adrenergic receptor, GUANOSINE-5'-TRIPHOSPHATE, ...
Authors:Papasergi-Scott, M.M, Skiniotis, G.
Deposit date:2023-03-08
Release date:2024-03-06
Last modified:2024-06-12
Method:ELECTRON MICROSCOPY (3.5 Å)
Cite:Time-resolved cryo-EM of G-protein activation by a GPCR.
Nature, 629, 2024
4R68
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BU of 4r68 by Molmil
Lactate Dehydrogenase in complex with inhibitor compound 31
Descriptor: (1S)-1-phenylethyl (4-chloro-3-{[(4S)-4-(2,6-dichlorophenyl)-2-hydroxy-6-oxocyclohex-1-en-1-yl]sulfanyl}phenyl)acetate, 1,4-DIHYDRONICOTINAMIDE ADENINE DINUCLEOTIDE, 4-(2-HYDROXYETHYL)-1-PIPERAZINE ETHANESULFONIC ACID, ...
Authors:Eigenbrot, C, Ultsch, M.
Deposit date:2014-08-22
Release date:2014-12-24
Last modified:2023-09-20
Method:X-RAY DIFFRACTION (2.112 Å)
Cite:Optimization of 5-(2,6-dichlorophenyl)-3-hydroxy-2-mercaptocyclohex-2-enones as potent inhibitors of human lactate dehydrogenase.
Bioorg.Med.Chem.Lett., 25, 2014
8OHA
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BU of 8oha by Molmil
Crystal structure of Leptospira interrogans GAPDH
Descriptor: DI(HYDROXYETHYL)ETHER, GLYCEROL, Glyceraldehyde-3-phosphate dehydrogenase, ...
Authors:Navas-Yuste, S, de la Paz, K, Querol-Garcia, J, Gomez-Quevedo, S, Rodriguez de Cordoba, S, Fernandez, F.J, Vega, M.C.
Deposit date:2023-03-20
Release date:2023-08-23
Method:X-RAY DIFFRACTION (2.37 Å)
Cite:The structure of Leptospira interrogans GAPDH sheds light into an immunoevasion factor that can target the anaphylatoxin C5a of innate immunity.
Front Immunol, 14, 2023
8GGS
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BU of 8ggs by Molmil
Locally refined cryoEM structure of receptor from beta-2-adrenergic receptor in complex with GTP-bound Gs heterotrimer (transition intermediate #11 of 20)
Descriptor: (5R,6R)-6-(methylamino)-5,6,7,8-tetrahydronaphthalene-1,2,5-triol, Beta-2 adrenergic receptor
Authors:Papasergi-Scott, M.M, Skiniotis, G.
Deposit date:2023-03-08
Release date:2024-03-06
Last modified:2024-06-05
Method:ELECTRON MICROSCOPY (3.5 Å)
Cite:Time-resolved cryo-EM of G-protein activation by a GPCR.
Nature, 629, 2024
8OMW
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BU of 8omw by Molmil
Crystal structure of the titin domain Fn3-20
Descriptor: CHLORIDE ION, Titin
Authors:Rees, M, Gautel, M.
Deposit date:2023-03-31
Release date:2023-08-23
Last modified:2023-08-30
Method:X-RAY DIFFRACTION (1.05 Å)
Cite:Structure determination and analysis of titin A-band fibronectin type III domains provides insights for disease-linked variants and protein oligomerisation.
J.Struct.Biol., 215, 2023
5MZ5
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BU of 5mz5 by Molmil
Crystal structure of aldehyde dehydrogenase 21 (ALDH21) from Physcomitrella patens in its apoform
Descriptor: 1,2-ETHANEDIOL, ALDH21), DI(HYDROXYETHYL)ETHER, ...
Authors:Kopecny, D, Koncitikova, R, Briozzo, P, Morera, S.
Deposit date:2017-01-30
Release date:2017-08-09
Last modified:2024-01-17
Method:X-RAY DIFFRACTION (2.15 Å)
Cite:The ALDH21 gene found in lower plants and some vascular plants codes for a NADP(+) -dependent succinic semialdehyde dehydrogenase.
Plant J., 92, 2017
8GFX
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BU of 8gfx by Molmil
CryoEM structure of beta-2-adrenergic receptor in complex with GTP-bound Gs heterotrimer (transition intermediate #3 of 20)
Descriptor: (5R,6R)-6-(methylamino)-5,6,7,8-tetrahydronaphthalene-1,2,5-triol, Beta-2 adrenergic receptor, GUANOSINE-5'-TRIPHOSPHATE, ...
Authors:Papasergi-Scott, M.M, Skiniotis, G.
Deposit date:2023-03-08
Release date:2024-03-06
Last modified:2024-06-12
Method:ELECTRON MICROSCOPY (3 Å)
Cite:Time-resolved cryo-EM of G-protein activation by a GPCR.
Nature, 629, 2024
8GFW
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BU of 8gfw by Molmil
CryoEM structure of beta-2-adrenergic receptor in complex with GTP-bound Gs heterotrimer (transition intermediate #2 of 20)
Descriptor: (5R,6R)-6-(methylamino)-5,6,7,8-tetrahydronaphthalene-1,2,5-triol, Beta-2 adrenergic receptor, GUANOSINE-5'-TRIPHOSPHATE, ...
Authors:Papasergi-Scott, M.M, Skiniotis, G.
Deposit date:2023-03-08
Release date:2024-03-06
Last modified:2024-06-12
Method:ELECTRON MICROSCOPY (3 Å)
Cite:Time-resolved cryo-EM of G-protein activation by a GPCR.
Nature, 629, 2024
8OIY
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BU of 8oiy by Molmil
Crystal structure of the R15908H missense variant of titin domain Fn3-3
Descriptor: Titin
Authors:Rees, M, Gautel, M.
Deposit date:2023-03-23
Release date:2023-08-23
Last modified:2023-08-30
Method:X-RAY DIFFRACTION (2.1 Å)
Cite:Structure determination and analysis of titin A-band fibronectin type III domains provides insights for disease-linked variants and protein oligomerisation.
J.Struct.Biol., 215, 2023
5U97
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BU of 5u97 by Molmil
Crystal structure of Co-CAO1 in complex with piceatannol
Descriptor: BENZOIC ACID, COBALT (II) ION, Carotenoid oxygenase 1, ...
Authors:Sui, X, Palczewski, K, Banerjee, S, Kiser, P.D.
Deposit date:2016-12-15
Release date:2017-05-31
Last modified:2023-10-25
Method:X-RAY DIFFRACTION (1.85 Å)
Cite:Structure and Spectroscopy of Alkene-Cleaving Dioxygenases Containing an Atypically Coordinated Non-Heme Iron Center.
Biochemistry, 56, 2017
8GGC
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BU of 8ggc by Molmil
CryoEM structure of beta-2-adrenergic receptor in complex with GTP-bound Gs heterotrimer (transition intermediate #18 of 20)
Descriptor: (5R,6R)-6-(methylamino)-5,6,7,8-tetrahydronaphthalene-1,2,5-triol, Beta-2 adrenergic receptor, GUANOSINE-5'-TRIPHOSPHATE, ...
Authors:Papasergi-Scott, M.M, Skiniotis, G.
Deposit date:2023-03-08
Release date:2024-03-06
Last modified:2024-06-12
Method:ELECTRON MICROSCOPY (3.4 Å)
Cite:Time-resolved cryo-EM of G-protein activation by a GPCR.
Nature, 629, 2024
8DNO
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BU of 8dno by Molmil
Human Brain Aldehyde Dehydrogenase 1 family, member A1
Descriptor: Retinal dehydrogenase 1
Authors:Tringides, M.L.
Deposit date:2022-07-11
Release date:2022-11-16
Last modified:2024-06-12
Method:ELECTRON MICROSCOPY (3.4 Å)
Cite:A cryo-electron microscopic approach to elucidate protein structures from human brain microsomes.
Life Sci Alliance, 6, 2023
3WTN
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BU of 3wtn by Molmil
Crystal Structure of Lymnaea stagnalis Acetylcholine Binding Protein Complexed with Desnitro-imidacloprid
Descriptor: (2Z)-1-[(6-chloropyridin-3-yl)methyl]imidazolidin-2-imine, Acetylcholine-binding protein, CADMIUM ION, ...
Authors:Okajima, T, Ihara, M, Yamashita, A, Oda, T, Matsuda, K.
Deposit date:2014-04-11
Release date:2015-02-04
Last modified:2023-11-08
Method:X-RAY DIFFRACTION (2.09 Å)
Cite:Studies on an acetylcholine binding protein identify a basic residue in loop G on the beta 1 strand as a new structural determinant of neonicotinoid actions
Mol.Pharmacol., 86, 2014

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数据于2024-07-17公开中

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