8OHA
Crystal structure of Leptospira interrogans GAPDH
Summary for 8OHA
Entry DOI | 10.2210/pdb8oha/pdb |
Descriptor | Glyceraldehyde-3-phosphate dehydrogenase, DI(HYDROXYETHYL)ETHER, GLYCEROL, ... (7 entities in total) |
Functional Keywords | gapdh, leptospira interrogans, immune evasion, innate immunity, complement system, hydrolase |
Biological source | Leptospira interrogans serovar Copenhageni str. Fiocruz L1-130 More |
Total number of polymer chains | 8 |
Total formula weight | 304279.44 |
Authors | Navas-Yuste, S.,de la Paz, K.,Querol-Garcia, J.,Gomez-Quevedo, S.,Rodriguez de Cordoba, S.,Fernandez, F.J.,Vega, M.C. (deposition date: 2023-03-20, release date: 2023-08-23) |
Primary citation | Navas-Yuste, S.,de la Paz, K.,Querol-Garcia, J.,Gomez-Quevedo, S.,Rodriguez de Cordoba, S.,Fernandez, F.J.,Vega, M.C. The structure of Leptospira interrogans GAPDH sheds light into an immunoevasion factor that can target the anaphylatoxin C5a of innate immunity. Front Immunol, 14:1190943-1190943, 2023 Cited by PubMed: 37409124DOI: 10.3389/fimmu.2023.1190943 PDB entries with the same primary citation |
Experimental method | X-RAY DIFFRACTION (2.37 Å) |
Structure validation
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