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4KN7	X-ray crystal structure of the Escherichia coli RNA polymerase in complex with Benzoxazinorifamycin-2c Descriptor: Benzoxazinorifamycin-2c, DNA-directed RNA polymerase subunit alpha, DNA-directed RNA polymerase subunit beta, ... Authors: Murakami, K.S. Deposit date: 2013-05-08 Release date: 2013-05-22 Last modified: 2023-09-20 Method: X-RAY DIFFRACTION (3.686 Å) Cite: X-ray Crystal Structures of the Escherichia coli RNA Polymerase in Complex with Benzoxazinorifamycins. J.Med.Chem., 56, 2013
8X6F	Cryo-EM structure of Staphylococcus aureus sigA-dependent RNAP-promoter open complex Descriptor: DNA (71-mer), DNA-directed RNA polymerase subunit alpha, DNA-directed RNA polymerase subunit beta, ... Authors: Yuan, L, Xu, L, Liu, Q, Feng, Y. Deposit date: 2023-11-21 Release date: 2024-06-05 Last modified: 2024-06-19 Method: ELECTRON MICROSCOPY (3.7 Å) Cite: Structural basis of promoter recognition by Staphylococcus aureus RNA polymerase. Nat Commun, 15, 2024
8X6G	Cryo-EM structure of Staphylococcus aureus sigB-dependent RNAP-promoter open complex Descriptor: DNA (70-mer), DNA-directed RNA polymerase subunit alpha, DNA-directed RNA polymerase subunit beta, ... Authors: Yuan, L, Xu, L, Liu, Q, Feng, Y. Deposit date: 2023-11-21 Release date: 2024-06-05 Last modified: 2024-06-19 Method: ELECTRON MICROSCOPY (3.3 Å) Cite: Structural basis of promoter recognition by Staphylococcus aureus RNA polymerase. Nat Commun, 15, 2024
4LK1	Crystal Structure Analysis of the E.coli holoenzyme Descriptor: DNA-directed RNA polymerase subunit alpha, DNA-directed RNA polymerase subunit beta, DNA-directed RNA polymerase subunit beta', ... Authors: Bae, B, Darst, S.A. Deposit date: 2013-07-05 Release date: 2013-11-13 Last modified: 2024-02-28 Method: X-RAY DIFFRACTION (3.8369 Å) Cite: Phage T7 Gp2 inhibition of Escherichia coli RNA polymerase involves misappropriation of sigma 70 domain 1.1. Proc.Natl.Acad.Sci.USA, 110, 2013
7EH0	Thermus thermophilus RNA polymerase transcription initiation complex containing a template-strand purine at position TSS-2, UpA RNA primer and CMPcPP Descriptor: 5'-O-[(S)-hydroxy{[(S)-hydroxy(phosphonooxy)phosphoryl]methyl}phosphoryl]cytidine, DNA (27-MER), DNA (5'-D(*CP*C*TP*GP*CP*AP*TP*CP*CP*GP*TP*GP*AP*GP*TP*AP*AP*AP*G)-3'), ... Authors: Li, L, Zhang, Y. Deposit date: 2021-03-27 Release date: 2021-07-14 Last modified: 2023-11-29 Method: X-RAY DIFFRACTION (2.808 Å) Cite: Promoter-sequence determinants and structural basis of primer-dependent transcription initiation in Escherichia coli . Proc.Natl.Acad.Sci.USA, 118, 2021
7EH2	Thermus thermophilus transcription initiation complex containing a template-strand pyrimidine at position TSS-2 and GpG RNA primer Descriptor: DNA (27-MER), DNA (5'-D(*CP*C*TP*GP*CP*AP*TP*CP*CP*GP*TP*GP*AP*GP*CP*CP*TP*AP*G)-3'), DNA-directed RNA polymerase subunit alpha, ... Authors: Li, L, Zhang, Y. Deposit date: 2021-03-27 Release date: 2021-07-14 Last modified: 2023-11-29 Method: X-RAY DIFFRACTION (3.34 Å) Cite: Promoter-sequence determinants and structural basis of primer-dependent transcription initiation in Escherichia coli . Proc.Natl.Acad.Sci.USA, 118, 2021
7EH1	Thermus thermophilus transcription initiation complex containing a template-strand purine at position TSS-2, GpG RNA primer, and CMPcPP Descriptor: 1,4-BUTANEDIOL, 5'-O-[(S)-hydroxy{[(S)-hydroxy(phosphonooxy)phosphoryl]methyl}phosphoryl]cytidine, DNA (27-MER), ... Authors: Li, L, Zhang, Y. Deposit date: 2021-03-27 Release date: 2021-07-14 Last modified: 2023-11-29 Method: X-RAY DIFFRACTION (2.9 Å) Cite: Promoter-sequence determinants and structural basis of primer-dependent transcription initiation in Escherichia coli . Proc.Natl.Acad.Sci.USA, 118, 2021
7CKQ	The cryo-EM structure of B. subtilis BmrR transcription activation complex Descriptor: DNA (50-MER), DNA-directed RNA polymerase subunit alpha, DNA-directed RNA polymerase subunit beta, ... Authors: Fang, C.L, Zhang, Y. Deposit date: 2020-07-18 Release date: 2020-12-16 Last modified: 2024-03-27 Method: ELECTRON MICROSCOPY (4.4 Å) Cite: The bacterial multidrug resistance regulator BmrR distorts promoter DNA to activate transcription. Nat Commun, 11, 2020
7C97	Cryo-EM structure of an Escherichia coli RNAP-promoter open complex (RPo) with SspA Descriptor: DNA (63-mer), DNA-directed RNA polymerase subunit alpha, DNA-directed RNA polymerase subunit beta, ... Authors: Lin, W, Feng, Y. Deposit date: 2020-06-05 Release date: 2020-08-12 Last modified: 2024-03-27 Method: ELECTRON MICROSCOPY (3.68 Å) Cite: Structural basis for transcription inhibition by E. coli SspA Nucleic Acids Res., 2020
7CHW	Cryo-EM structure of an Escherichia coli RNAP-promoter open complex (RPo) Descriptor: DNA (63-MER), DNA-directed RNA polymerase subunit alpha, DNA-directed RNA polymerase subunit beta, ... Authors: Lin, W, Feng, Y. Deposit date: 2020-07-06 Release date: 2020-08-12 Last modified: 2024-03-27 Method: ELECTRON MICROSCOPY (3.58 Å) Cite: Structural basis for transcription inhibition by E. coli SspA Nucleic Acids Res., 2020
7F0R	Cryo-EM structure of Pseudomonas aeruginosa SutA transcription activation complex Descriptor: DNA (70-MER), DNA-directed RNA polymerase subunit alpha, DNA-directed RNA polymerase subunit beta, ... Authors: He, D.W, You, L.L, Zhang, Y. Deposit date: 2021-06-06 Release date: 2022-07-27 Last modified: 2024-06-12 Method: ELECTRON MICROSCOPY (5.8 Å) Cite: Pseudomonas aeruginosa SutA wedges RNAP lobe domain open to facilitate promoter DNA unwinding. Nat Commun, 13, 2022
4LLG	Crystal Structure Analysis of the E.coli holoenzyme/Gp2 complex Descriptor: Bacterial RNA polymerase inhibitor, DNA-directed RNA polymerase subunit alpha, DNA-directed RNA polymerase subunit beta, ... Authors: Bae, B, Darst, S.A. Deposit date: 2013-07-09 Release date: 2013-11-13 Last modified: 2024-02-28 Method: X-RAY DIFFRACTION (3.7936 Å) Cite: Phage T7 Gp2 inhibition of Escherichia coli RNA polymerase involves misappropriation of sigma 70 domain 1.1. Proc.Natl.Acad.Sci.USA, 110, 2013
4LJZ	Crystal Structure Analysis of the E.coli holoenzyme Descriptor: DNA-directed RNA polymerase subunit alpha, DNA-directed RNA polymerase subunit beta, DNA-directed RNA polymerase subunit beta', ... Authors: Bae, B, Darst, S.A. Deposit date: 2013-07-05 Release date: 2013-11-13 Last modified: 2024-02-28 Method: X-RAY DIFFRACTION (3.5871 Å) Cite: Phage T7 Gp2 inhibition of Escherichia coli RNA polymerase involves misappropriation of sigma 70 domain 1.1. Proc.Natl.Acad.Sci.USA, 110, 2013
4LK0	Crystal Structure Analysis of the E.coli holoenzyme/T7 Gp2 complex Descriptor: Bacterial RNA polymerase inhibitor, DNA-directed RNA polymerase subunit alpha, DNA-directed RNA polymerase subunit beta, ... Authors: Bae, B, Darst, S.A. Deposit date: 2013-07-05 Release date: 2013-11-13 Last modified: 2024-02-28 Method: X-RAY DIFFRACTION (3.9103 Å) Cite: Phage T7 Gp2 inhibition of Escherichia coli RNA polymerase involves misappropriation of sigma 70 domain 1.1. Proc.Natl.Acad.Sci.USA, 110, 2013
5ZX2	Mycobacterium tuberculosis RNA polymerase transcription initiation complex with ECF sigma factor sigma H and 7nt RNA Descriptor: DNA (47-MER), DNA (48-MER), DNA-directed RNA polymerase subunit alpha, ... Authors: Li, L, Zhang, Y. Deposit date: 2018-05-17 Release date: 2019-03-20 Last modified: 2023-11-22 Method: X-RAY DIFFRACTION (2.8 Å) Cite: Structural basis for transcription initiation by bacterial ECF sigma factors. Nat Commun, 10, 2019
5ZX3	Mycobacterium tuberculosis RNA polymerase holoenzyme with ECF sigma factor sigma H Descriptor: DNA-directed RNA polymerase subunit alpha, DNA-directed RNA polymerase subunit beta, DNA-directed RNA polymerase subunit beta', ... Authors: Li, L, Zhang, Y. Deposit date: 2018-05-17 Release date: 2019-03-20 Last modified: 2023-11-22 Method: X-RAY DIFFRACTION (2.751 Å) Cite: Structural basis for transcription initiation by bacterial ECF sigma factors. Nat Commun, 10, 2019
7W5Y	Cryo-EM structure of SoxS-dependent transcription activation complex with fpr promoter DNA Descriptor: DNA-directed RNA polymerase subunit alpha, DNA-directed RNA polymerase subunit beta, DNA-directed RNA polymerase subunit beta', ... Authors: Lin, W, Feng, Y. Deposit date: 2021-11-30 Release date: 2022-10-26 Last modified: 2024-06-26 Method: ELECTRON MICROSCOPY (4.2 Å) Cite: Structural basis of three different transcription activation strategies adopted by a single regulator SoxS. Nucleic Acids Res., 50, 2022
7W5W	Cryo-EM structure of SoxS-dependent transcription activation complex with micF promoter DNA Descriptor: DNA-directed RNA polymerase subunit alpha, DNA-directed RNA polymerase subunit beta, DNA-directed RNA polymerase subunit beta', ... Authors: Lin, W, Feng, Y. Deposit date: 2021-11-30 Release date: 2022-10-26 Last modified: 2024-06-26 Method: ELECTRON MICROSCOPY (4.55 Å) Cite: Structural basis of three different transcription activation strategies adopted by a single regulator SoxS. Nucleic Acids Res., 50, 2022
7W5X	Cryo-EM structure of SoxS-dependent transcription activation complex with zwf promoter DNA Descriptor: DNA-directed RNA polymerase subunit alpha, DNA-directed RNA polymerase subunit beta, DNA-directed RNA polymerase subunit beta', ... Authors: Lin, W, Feng, Y, Shi, J. Deposit date: 2021-11-30 Release date: 2022-10-26 Last modified: 2024-06-26 Method: ELECTRON MICROSCOPY (3.4 Å) Cite: Structural basis of three different transcription activation strategies adopted by a single regulator SoxS. Nucleic Acids Res., 50, 2022
6B6H	The cryo-EM structure of a bacterial class I transcription activation complex Descriptor: ADENOSINE-3',5'-CYCLIC-MONOPHOSPHATE, DNA-directed RNA polymerase subunit alpha, DNA-directed RNA polymerase subunit beta, ... Authors: Liu, B, Hong, C, Huang, R, Yu, Z, Steitz, T.A. Deposit date: 2017-10-02 Release date: 2017-11-15 Last modified: 2024-03-13 Method: ELECTRON MICROSCOPY (3.9 Å) Cite: Structural basis of bacterial transcription activation. Science, 358, 2017
7XYA	The cryo-EM structure of an AlpA-loading complex Descriptor: AlpA, DNA-directed RNA polymerase subunit alpha, DNA-directed RNA polymerase subunit beta, ... Authors: Wen, A, Feng, Y. Deposit date: 2022-06-01 Release date: 2022-07-20 Last modified: 2022-08-24 Method: ELECTRON MICROSCOPY (3.3 Å) Cite: Structural basis of AlpA-dependent transcription antitermination. Nucleic Acids Res., 50, 2022
7XUI	Cryo-EM structure of sigma70 bound HK022 putRNA-associated E.coli RNA polymerase elongation complex Descriptor: DNA-directed RNA polymerase subunit alpha, DNA-directed RNA polymerase subunit beta, DNA-directed RNA polymerase subunit beta', ... Authors: Hwang, S, Kang, J.Y. Deposit date: 2022-05-18 Release date: 2022-08-10 Last modified: 2024-07-03 Method: ELECTRON MICROSCOPY (3.61 Å) Cite: Structural basis of transcriptional regulation by a nascent RNA element, HK022 putRNA. Nat Commun, 13, 2022
7YE1	The cryo-EM structure of C. crescentus GcrA-TACup Descriptor: Cell cycle regulatory protein GcrA, DNA (57-MER)-non template, DNA (57-MER)-template, ... Authors: Wu, X.X, Zhang, Y. Deposit date: 2022-07-05 Release date: 2023-01-18 Last modified: 2024-07-03 Method: ELECTRON MICROSCOPY (3.7 Å) Cite: Cryo-EM structures of Caulobacter crescentus transcription activation complex with an essential cell cycle regulator GcrA Nucleic Acids Res., 2023
7YE2	The cryo-EM structure of C. crescentus GcrA-TACdown Descriptor: Cell cycle regulatory protein GcrA, DNA (90-MER)-non template, DNA (90-MER)-template, ... Authors: Wu, X.X, Zhang, Y. Deposit date: 2022-07-05 Release date: 2023-01-18 Last modified: 2024-07-03 Method: ELECTRON MICROSCOPY (3.8 Å) Cite: Cryo-EM structures of Caulobacter crescentus transcription activation complex with an essential cell cycle regulator GcrA Nucleic Acids Res., 2023
6CA0	Cryo-EM structure of E. coli RNAP sigma70 open complex Descriptor: DNA (35-MER), DNA (45-MER), DNA (5'-D(P*GP*CP*CP*GP*CP*GP*TP*CP*AP*GP*A)-3'), ... Authors: Narayanan, A, Vago, F, Li, K, Qayyum, M.Z, Yernool, D, Jiang, W, Murakami, K.S. Deposit date: 2018-01-29 Release date: 2018-02-28 Last modified: 2024-03-13 Method: ELECTRON MICROSCOPY (5.75 Å) Cite: Cryo-EM structure ofEscherichia colisigma70RNA polymerase and promoter DNA complex revealed a role of sigma non-conserved region during the open complex formation. J. Biol. Chem., 293, 2018

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