1QLL
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![BU of 1qll by Molmil](/molmil-images/mine/1qll) | Piratoxin-II (Prtx-II) - a K49 PLA2 from Bothrops pirajai | Descriptor: | N-TRIDECANOIC ACID, PHOSPHOLIPASE A2 | Authors: | Lee, W.-H, Polikarpov, I. | Deposit date: | 1999-09-01 | Release date: | 2000-09-07 | Last modified: | 2023-12-13 | Method: | X-RAY DIFFRACTION (2.04 Å) | Cite: | Structural Basis for Low Catalytic Activity in Lys49 Phospholipases A2-A Hypothesis: The Crystal Structure of Piratoxin II Complexed to Fatty Acid Biochemistry, 40, 2001
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2PH4
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![BU of 2ph4 by Molmil](/molmil-images/mine/2ph4) | Crystal structure of a novel Arg49 phospholipase A2 homologue from Zhaoermia mangshanensis venom | Descriptor: | DI(HYDROXYETHYL)ETHER, SULFATE ION, Zhaoermiatoxin | Authors: | Murakami, M.T, Kuch, U, Mebs, D, Arni, R.K. | Deposit date: | 2007-04-10 | Release date: | 2008-03-18 | Last modified: | 2023-08-30 | Method: | X-RAY DIFFRACTION (2.05 Å) | Cite: | Crystal structure of a novel myotoxic Arg49 phospholipase A(2) homolog (zhaoermiatoxin) from Zhaoermia mangshanensis snake venom: Insights into Arg49 coordination and the role of Lys122 in the polarization of the C-terminus. Toxicon, 51, 2008
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5VFM
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![BU of 5vfm by Molmil](/molmil-images/mine/5vfm) | |
4NTW
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![BU of 4ntw by Molmil](/molmil-images/mine/4ntw) | Structure of acid-sensing ion channel in complex with snake toxin | Descriptor: | 2-acetamido-2-deoxy-beta-D-glucopyranose, Acid-sensing ion channel 1, Basic phospholipase A2 homolog Tx-beta, ... | Authors: | Baconguis, I, Bohlen, C.J, Goehring, A, Julius, D, Gouaux, E. | Deposit date: | 2013-12-02 | Release date: | 2014-02-19 | Last modified: | 2020-07-29 | Method: | X-RAY DIFFRACTION (2.07 Å) | Cite: | X-ray structure of Acid-sensing ion channel 1-snake toxin complex reveals open state of a na(+)-selective channel. Cell(Cambridge,Mass.), 156, 2014
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2AOZ
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![BU of 2aoz by Molmil](/molmil-images/mine/2aoz) | Crystal structure of the myotoxin-II from Atropoides nummifer venom | Descriptor: | Phospholipase A2 homolog, SULFATE ION | Authors: | Melo, C.C, Murakami, M.T, Angulo, Y, Lomonte, B, Arni, R.K. | Deposit date: | 2005-08-15 | Release date: | 2006-07-25 | Last modified: | 2023-08-23 | Method: | X-RAY DIFFRACTION (2.08 Å) | Cite: | Structure of myotoxin II, a catalytically inactive Lys49 phospholipase A2 homologue from Atropoides nummifer venom. Acta Crystallogr.,Sect.F, 62, 2006
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4K06
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![BU of 4k06 by Molmil](/molmil-images/mine/4k06) | Crystal structure of MTX-II from Bothrops brazili venom complexed with polyethylene glycol | Descriptor: | 2-(2-(2-(2-(2-(2-ETHOXYETHOXY)ETHOXY)ETHOXY)ETHOXY)ETHOXY)ETHANOL, 2-{2-[2-(2-{2-[2-(2-ETHOXY-ETHOXY)-ETHOXY]-ETHOXY}-ETHOXY)-ETHOXY]-ETHOXY}-ETHANOL, MTX-II, ... | Authors: | Fernandes, C.A.H, Comparetti, E.J, Borges, R.J, Fontes, M.R.M. | Deposit date: | 2013-04-03 | Release date: | 2013-11-13 | Last modified: | 2013-11-27 | Method: | X-RAY DIFFRACTION (2.08 Å) | Cite: | Structural bases for a complete myotoxic mechanism: Crystal structures of two non-catalytic phospholipases A2-like from Bothrops brazili venom. Biochim.Biophys.Acta, 1834, 2013
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2QU9
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![BU of 2qu9 by Molmil](/molmil-images/mine/2qu9) | Crystal structure of the complex of group II phospholipase A2 with Eugenol | Descriptor: | 2-methoxy-4-[(1E)-prop-1-en-1-yl]phenol, Phospholipase A2 VRV-PL-VIIIa, SULFATE ION | Authors: | Kumar, S, Vikram, G, Singh, N, Sinha, M, Sharma, S, Kaur, P, Srinivasan, A, Singh, T.P. | Deposit date: | 2007-08-04 | Release date: | 2007-08-14 | Last modified: | 2023-10-25 | Method: | X-RAY DIFFRACTION (2.08 Å) | Cite: | Crystal structure of the complex of group II phospholipase A2 with Eugenol To be Published
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5VFJ
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![BU of 5vfj by Molmil](/molmil-images/mine/5vfj) | |
1LE7
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![BU of 1le7 by Molmil](/molmil-images/mine/1le7) | CARBOXYLIC ESTER HYDROLASE, C 2 2 21 space group | Descriptor: | (4S)-2-METHYL-2,4-PENTANEDIOL, CALCIUM ION, Group X Secretory Phospholipase A2 | Authors: | Pan, Y.H, Jain, M.K, Bahnson, B.J. | Deposit date: | 2002-04-09 | Release date: | 2002-08-14 | Last modified: | 2023-08-16 | Method: | X-RAY DIFFRACTION (2.09 Å) | Cite: | Crystal structure of human group X secreted phospholipase A2. Electrostatically neutral interfacial surface targets zwitterionic membranes. J.Biol.Chem., 277, 2002
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1POE
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![BU of 1poe by Molmil](/molmil-images/mine/1poe) | |
1M8T
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![BU of 1m8t by Molmil](/molmil-images/mine/1m8t) | Structure of an acidic Phospholipase A2 from the venom of Ophiophagus hannah at 2.1 resolution from a hemihedrally twinned crystal form | Descriptor: | CALCIUM ION, HEXANE-1,6-DIOL, Phospholipase a2 | Authors: | Xu, S, Gu, L, Wang, Q, Shu, Y, Lin, Z. | Deposit date: | 2002-07-26 | Release date: | 2003-09-02 | Last modified: | 2023-10-25 | Method: | X-RAY DIFFRACTION (2.1 Å) | Cite: | Structure of a king cobra phospholipase A2 determined from a hemihedrally twinned crystal. Acta Crystallogr.,Sect.D, 59, 2003
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1KQU
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![BU of 1kqu by Molmil](/molmil-images/mine/1kqu) | Human phospholipase A2 complexed with a substrate anologue | Descriptor: | 6-PHENYL-4(R)-(7-PHENYL-HEPTANOYLAMINO)-HEXANOIC ACID, CALCIUM ION, Phospholipase A2, ... | Authors: | Tyndall, J.D, Martin, J.L. | Deposit date: | 2002-01-07 | Release date: | 2003-11-11 | Last modified: | 2023-08-16 | Method: | X-RAY DIFFRACTION (2.1 Å) | Cite: | D-Tyrosine as a chiral precusor to potent inhibitors of human nonpancreatic secretory phospholipase A2 (IIa) with antiinflammatory activity. Chembiochem, 4, 2003
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7ROX
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![BU of 7rox by Molmil](/molmil-images/mine/7rox) | BthTX-I complexed with inhibitor MMV | Descriptor: | 12-methoxy-Nb-methylvoachalotine, Basic phospholipase A2 homolog bothropstoxin-I | Authors: | Borges, R.J, De Marino, I, Uson, I, Fontes, M.R.M. | Deposit date: | 2021-08-02 | Release date: | 2022-11-09 | Last modified: | 2023-10-25 | Method: | X-RAY DIFFRACTION (2.1 Å) | Cite: | Structural and functional studies of a snake venom phospholipase A 2 -like protein complexed to an inhibitor from Tabernaemontana catharinensis. Biochimie, 206, 2023
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2PVT
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![BU of 2pvt by Molmil](/molmil-images/mine/2pvt) | |
3P2P
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![BU of 3p2p by Molmil](/molmil-images/mine/3p2p) | ENHANCED ACTIVITY AND ALTERED SPECIFICITY OF PHOSPHOLIPASE A2 BY DELETION OF A SURFACE LOOP | Descriptor: | CALCIUM ION, PHOSPHOLIPASE A2 | Authors: | Dijkstra, B.W, Thunnissen, M.M.G.M, Kalk, K.H, Drenth, J. | Deposit date: | 1989-11-29 | Release date: | 1990-01-15 | Last modified: | 2024-06-05 | Method: | X-RAY DIFFRACTION (2.1 Å) | Cite: | Enhanced activity and altered specificity of phospholipase A2 by deletion of a surface loop. Science, 244, 1989
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3JR8
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![BU of 3jr8 by Molmil](/molmil-images/mine/3jr8) | Crystal Structure of BthTX-II (Asp49-PLA2 from Bothrops jararacussu snake venom) with calcium ions | Descriptor: | CALCIUM ION, Phospholipase A2 bothropstoxin-2 | Authors: | Borges, R.J, dos Santos, J.I, Fontes, M.R.M. | Deposit date: | 2009-09-08 | Release date: | 2010-09-08 | Last modified: | 2023-09-06 | Method: | X-RAY DIFFRACTION (2.1 Å) | Cite: | Structural, functional, and bioinformatics studies reveal a new snake venom homologue phospholipase A2 class. Proteins, 79, 2011
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1POD
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![BU of 1pod by Molmil](/molmil-images/mine/1pod) | |
3BP2
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![BU of 3bp2 by Molmil](/molmil-images/mine/3bp2) | |
2DPZ
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![BU of 2dpz by Molmil](/molmil-images/mine/2dpz) | |
4K09
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![BU of 4k09 by Molmil](/molmil-images/mine/4k09) | |
1JIA
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![BU of 1jia by Molmil](/molmil-images/mine/1jia) | |
6CE2
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![BU of 6ce2 by Molmil](/molmil-images/mine/6ce2) | Crystal structure of Myotoxin I (MjTX-I) from Bothrops moojeni complexed to inhibitor suramin | Descriptor: | 2-{2-[2-(2-{2-[2-(2-ETHOXY-ETHOXY)-ETHOXY]-ETHOXY}-ETHOXY)-ETHOXY]-ETHOXY}-ETHANOL, 8,8'-[CARBONYLBIS[IMINO-3,1-PHENYLENECARBONYLIMINO(4-METHYL-3,1-PHENYLENE)CARBONYLIMINO]]BIS-1,3,5-NAPHTHALENETRISULFON IC ACID, Basic phospholipase A2 homolog 1 | Authors: | Salvador, G.H.M, Fontes, M.R.M. | Deposit date: | 2018-02-10 | Release date: | 2018-07-25 | Last modified: | 2023-10-04 | Method: | X-RAY DIFFRACTION (2.15 Å) | Cite: | Structural and functional characterization of suramin-bound MjTX-I from Bothrops moojeni suggests a particular myotoxic mechanism. Sci Rep, 8, 2018
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3VC0
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![BU of 3vc0 by Molmil](/molmil-images/mine/3vc0) | Crystal structure of Taipoxin beta subunit isoform 1 | Descriptor: | Phospholipase A2 homolog, taipoxin beta chain | Authors: | Cendron, L, Micetic, I, Polverino de Laureto, P, Beltramini, M, Paoli, M. | Deposit date: | 2012-01-03 | Release date: | 2012-07-25 | Last modified: | 2023-09-13 | Method: | X-RAY DIFFRACTION (2.15 Å) | Cite: | Structural analysis of trimeric phospholipase A(2) neurotoxin from the Australian taipan snake venom. Febs J., 279, 2012
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4WTB
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![BU of 4wtb by Molmil](/molmil-images/mine/4wtb) | BthTX-I, a svPLA2s-like toxin, complexed with zinc ions | Descriptor: | Basic phospholipase A2 homolog bothropstoxin-1, CHLORIDE ION, SULFATE ION, ... | Authors: | Borges, R.J, Fontes, M.R.M. | Deposit date: | 2014-10-29 | Release date: | 2015-11-11 | Last modified: | 2023-09-27 | Method: | X-RAY DIFFRACTION (2.16 Å) | Cite: | Functional and structural studies of a Phospholipase A2-like protein complexed to zinc ions: Insights on its myotoxicity and inhibition mechanism. Biochim. Biophys. Acta, 1861, 2017
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3I3H
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![BU of 3i3h by Molmil](/molmil-images/mine/3i3h) | |