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1QBY
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BU of 1qby by Molmil
THE SOLUTION STRUCTURE OF A BAY-REGION 1R-BENZ[A]ANTHRACENE OXIDE ADDUCT AT THE N6 POSITION OF ADENINE OF AN OLIGODEOXYNUCLEOTIDE CONTAINING THE HUMAN N-RAS CODON 61 SEQUENCE
Descriptor: 1R,2S,3R,4S-TETRAHYDRO-BENZO[A]ANTHRACENE-2,3,4-TRIOL, 5'-D(*CP*GP*GP*AP*CP*(BZA)AP*AP*GP*AP*AP*G)-3', 5'-D(*CP*TP*TP*CP*TP*TP*GP*TP*CP*CP* G)-3'
Authors:Li, Z, Mao, H, Kim, H.-Y, Tamura, P.J, Harris, C.M, Harris, T.M, Stone, M.P.
Deposit date:1999-04-27
Release date:1999-05-06
Last modified:2022-03-02
Method:SOLUTION NMR
Cite:Intercalation of the (-)-(1R,2S,3R, 4S)-N6-[1-benz[a]anthracenyl]-2'-deoxyadenosyl adduct in an oligodeoxynucleotide containing the human N-ras codon 61 sequence.
Biochemistry, 38, 1999
8I4X
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BU of 8i4x by Molmil
Cryo-EM structure of 5-subunit Smc5/6
Descriptor: E3 SUMO-protein ligase MMS21, Non-structural maintenance of chromosome element 5, Nse6, ...
Authors:Qian, L, Jun, Z, Xiang, Z, Zhaoning, W, Tong, C, Duo, J, Zhenguo, C, Wang, L.
Deposit date:2023-01-21
Release date:2024-06-26
Last modified:2024-10-30
Method:ELECTRON MICROSCOPY (8.5 Å)
Cite:Cryo-EM structures of Smc5/6 in multiple states reveal its assembly and functional mechanisms.
Nat.Struct.Mol.Biol., 31, 2024
8I21
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BU of 8i21 by Molmil
Cryo-EM structure of 6-subunit Smc5/6 arm region
Descriptor: E3 SUMO-protein ligase MMS21, Structural maintenance of chromosomes protein 5, Structural maintenance of chromosomes protein 6
Authors:Jun, Z, Qian, L, Xiang, Z, Tong, C, Zhaoning, W, Duo, J, Zhenguo, C, Lanfeng, W.
Deposit date:2023-01-13
Release date:2024-06-26
Last modified:2024-10-30
Method:ELECTRON MICROSCOPY (6.02 Å)
Cite:Cryo-EM structures of Smc5/6 in multiple states reveal its assembly and functional mechanisms.
Nat.Struct.Mol.Biol., 31, 2024
3L15
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BU of 3l15 by Molmil
Human Tead2 transcriptional factor
Descriptor: GLYCEROL, Transcriptional enhancer factor TEF-4
Authors:Tomchick, D.R, Luo, X, Tian, W.
Deposit date:2009-12-10
Release date:2010-04-07
Last modified:2017-11-01
Method:X-RAY DIFFRACTION (2 Å)
Cite:Structural and functional analysis of the YAP-binding domain of human TEAD2.
Proc.Natl.Acad.Sci.USA, 107, 2010
4JL9
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BU of 4jl9 by Molmil
Crystal structure of mouse TBK1 bound to BX795
Descriptor: N-(3-{[5-iodo-4-({3-[(thiophen-2-ylcarbonyl)amino]propyl}amino)pyrimidin-2-yl]amino}phenyl)pyrrolidine-1-carboxamide, Serine/threonine-protein kinase TBK1
Authors:Li, P, Shu, C.
Deposit date:2013-03-12
Release date:2013-06-19
Last modified:2024-02-28
Method:X-RAY DIFFRACTION (3.0999 Å)
Cite:Structural Insights into the Functions of TBK1 in Innate Antimicrobial Immunity.
Structure, 21, 2013
1VY4
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BU of 1vy4 by Molmil
Crystal structure of the Thermus thermophilus 70S ribosome in the pre-attack state of peptide bond formation containing acylated tRNA-substrates in the A and P sites.
Descriptor: 16S Ribosomal RNA, 23S Ribosomal RNA, 30S ribosomal protein S10, ...
Authors:Polikanov, Y.S, Steitz, T.A, Innis, C.A.
Deposit date:2014-05-13
Release date:2014-08-20
Last modified:2023-12-27
Method:X-RAY DIFFRACTION (2.6 Å)
Cite:A proton wire to couple aminoacyl-tRNA accommodation and peptide-bond formation on the ribosome.
Nat.Struct.Mol.Biol., 21, 2014
3DU6
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BU of 3du6 by Molmil
Structure of the catalytic subunit of telomerase, TERT
Descriptor: Telomerase reverse transcriptase
Authors:Skordalakes, E.
Deposit date:2008-07-16
Release date:2008-08-26
Last modified:2024-02-21
Method:X-RAY DIFFRACTION (2.71 Å)
Cite:Structure of the Tribolium castaneum telomerase catalytic subunit TERT.
Nature, 455, 2008
3DB3
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BU of 3db3 by Molmil
Crystal structure of the tandem tudor domains of the E3 ubiquitin-protein ligase UHRF1 in complex with trimethylated histone H3-K9 peptide
Descriptor: E3 ubiquitin-protein ligase UHRF1, Trimethylated histone H3-K9 peptide
Authors:Walker, J.R, Avvakumov, G.V, Xue, S, Dong, A, Li, Y, Bountra, C, Weigelt, J, Arrowsmith, C.H, Edwards, A.M, Bochkarev, A, Dhe-Paganon, S, Structural Genomics Consortium (SGC)
Deposit date:2008-05-30
Release date:2008-09-16
Last modified:2012-04-18
Method:X-RAY DIFFRACTION (2.4 Å)
Cite:Recognition of multivalent histone states associated with heterochromatin by UHRF1 protein.
J.Biol.Chem., 286, 2011
1LX7
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BU of 1lx7 by Molmil
Structure of E. coli uridine phosphorylase at 2.0A
Descriptor: uridine phosphorylase
Authors:Burling, T, Buglino, J.A, Kniewel, R, Chadna, T, Beckwith, A, Lima, C.D, Burley, S.K, New York SGX Research Center for Structural Genomics (NYSGXRC)
Deposit date:2002-06-04
Release date:2002-06-12
Last modified:2024-10-30
Method:X-RAY DIFFRACTION (2 Å)
Cite:Structure of Escherichia coli uridine phosphorylase at 2.0 A.
Acta Crystallogr.,Sect.D, 59, 2003
8C3N
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BU of 8c3n by Molmil
Stapled peptide SP30 in complex with humanised RadA mutant HumRadA22
Descriptor: 4,6-diethylpyrimidin-2-amine, ADENOSINE-5'-DIPHOSPHATE, Breast cancer type 2 susceptibility protein, ...
Authors:Pantelejevs, T, Hyvonen, M.
Deposit date:2022-12-27
Release date:2023-03-08
Last modified:2024-10-23
Method:X-RAY DIFFRACTION (1.21 Å)
Cite:A recombinant approach for stapled peptide discovery yields inhibitors of the RAD51 recombinase.
Chem Sci, 14, 2023
4JLC
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BU of 4jlc by Molmil
Crystal structure of mouse TBK1 bound to SU6668
Descriptor: 3-{2,4-dimethyl-5-[(Z)-(2-oxo-1,2-dihydro-3H-indol-3-ylidene)methyl]-1H-pyrrol-3-yl}propanoic acid, Serine/threonine-protein kinase TBK1
Authors:Li, P.
Deposit date:2013-03-12
Release date:2013-06-19
Last modified:2023-09-20
Method:X-RAY DIFFRACTION (3 Å)
Cite:Structural Insights into the Functions of TBK1 in Innate Antimicrobial Immunity.
Structure, 21, 2013
7BCY
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BU of 7bcy by Molmil
X-ray structure of WDR5delta24 bound to the Kaposi's sarcoma herpesvirus LANA win motif peptide
Descriptor: ORF 73, WD repeat-containing protein 5
Authors:McVey, C.E, Kaye, K.M.
Deposit date:2020-12-21
Release date:2021-12-08
Last modified:2024-11-13
Method:X-RAY DIFFRACTION (1.5 Å)
Cite:MLL1 is regulated by KSHV LANA and is important for virus latency.
Nucleic Acids Res., 49, 2021
7BED
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BU of 7bed by Molmil
X-ray structure of WDR5 bound to the WDR5 win motif peptide
Descriptor: SULFATE ION, WD repeat-containing protein 5
Authors:McVey, C.E, Kaye, K.M.
Deposit date:2020-12-23
Release date:2021-12-08
Last modified:2024-01-31
Method:X-RAY DIFFRACTION (1.26 Å)
Cite:MLL1 is regulated by KSHV LANA and is important for virus latency.
Nucleic Acids Res., 49, 2021
1PVO
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BU of 1pvo by Molmil
X-ray crystal structure of Rho transcription termination factor in complex with ssRNA substrate and ANPPNP
Descriptor: 5'-R(P*UP*C)-3', PHOSPHOAMINOPHOSPHONIC ACID-ADENYLATE ESTER, Transcription termination factor rho
Authors:Skordalakes, E, Berger, J.M.
Deposit date:2003-06-27
Release date:2003-07-22
Last modified:2023-08-16
Method:X-RAY DIFFRACTION (3 Å)
Cite:Structure of the Rho transcription terminator: mechanism of mRNA recognition and helicase loading
Cell(Cambridge,Mass.), 114, 2003
1UB4
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BU of 1ub4 by Molmil
crystal structure of MazEF complex
Descriptor: MazE protein, MazF protein
Authors:Kamada, K, Hanaoka, F, Burley, S.K, New York SGX Research Center for Structural Genomics (NYSGXRC)
Deposit date:2003-03-28
Release date:2003-05-20
Last modified:2023-12-27
Method:X-RAY DIFFRACTION (1.7 Å)
Cite:Crystal Structure of the MazE/MazF Complex. Molecular Bases of Antidote-Toxin Recognition
Mol.Cell, 11, 2003
3GCB
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BU of 3gcb by Molmil
GAL6 (YEAST BLEOMYCIN HYDROLASE) MUTANT C73A/DELTAK454
Descriptor: GAL6, GLYCEROL, SULFATE ION
Authors:Joshua-Tor, L, Zheng, W, Johnston, S.A.
Deposit date:1998-02-27
Release date:1998-10-21
Last modified:2024-05-22
Method:X-RAY DIFFRACTION (1.87 Å)
Cite:The unusual active site of Gal6/bleomycin hydrolase can act as a carboxypeptidase, aminopeptidase, and peptide ligase.
Cell(Cambridge,Mass.), 93, 1998
3DU5
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BU of 3du5 by Molmil
Structure of the catalytic subunit of telomerase, TERT
Descriptor: Telomerase reverse transcriptase
Authors:Skordalakes, E.
Deposit date:2008-07-16
Release date:2008-08-26
Last modified:2024-02-21
Method:X-RAY DIFFRACTION (3.25 Å)
Cite:Structure of the Tribolium castaneum telomerase catalytic subunit TERT.
Nature, 455, 2008
2AXZ
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BU of 2axz by Molmil
Crystal structure of PrgX/cCF10 complex
Descriptor: LVTLVFV peptide, PrgX, TPPKEVT(MSE) peptide
Authors:Shi, K, Brown, C.K, Gu, Z.Y, Kozlowicz, B.K, Dunny, G.M, Ohlendorf, D.H, Earhart, C.A.
Deposit date:2005-09-06
Release date:2005-12-06
Last modified:2024-10-30
Method:X-RAY DIFFRACTION (3 Å)
Cite:Structure of peptide sex pheromone receptor PrgX and PrgX/pheromone complexes and regulation of conjugation in Enterococcus faecalis.
Proc.Natl.Acad.Sci.Usa, 102, 2005
2AXV
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BU of 2axv by Molmil
Structure of PrgX Y153C mutant
Descriptor: PrgX
Authors:Shi, K, Brown, C.K, Gu, Z.Y, Kozlowicz, B.K, Dunny, G.M, Ohlendorf, D.H, Earhart, C.A.
Deposit date:2005-09-06
Release date:2005-12-06
Last modified:2024-02-14
Method:X-RAY DIFFRACTION (3 Å)
Cite:Structure of peptide sex pheromone receptor PrgX and PrgX/pheromone complexes and regulation of conjugation in Enterococcus faecalis.
Proc.Natl.Acad.Sci.Usa, 102, 2005
1A77
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BU of 1a77 by Molmil
FLAP ENDONUCLEASE-1 FROM METHANOCOCCUS JANNASCHII
Descriptor: FLAP ENDONUCLEASE-1 PROTEIN, MAGNESIUM ION
Authors:Hwang, K.Y, Baek, K, Kim, H, Cho, Y.
Deposit date:1998-03-20
Release date:1999-08-03
Last modified:2024-02-07
Method:X-RAY DIFFRACTION (2 Å)
Cite:The crystal structure of flap endonuclease-1 from Methanococcus jannaschii.
Nat.Struct.Biol., 5, 1998
1BHL
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BU of 1bhl by Molmil
CACODYLATED CATALYTIC DOMAIN OF HIV-1 INTEGRASE
Descriptor: HIV-1 INTEGRASE
Authors:Maignan, S, Guilloteau, J.P, Zhou-Liu, Q, Clement-Mella, C, Mikol, V.
Deposit date:1998-06-10
Release date:1998-10-14
Last modified:2023-08-02
Method:X-RAY DIFFRACTION (2.2 Å)
Cite:Crystal structures of the catalytic domain of HIV-1 integrase free and complexed with its metal cofactor: high level of similarity of the active site with other viral integrases.
J.Mol.Biol., 282, 1998
1BI4
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BU of 1bi4 by Molmil
CATALYTIC DOMAIN OF HIV-1 INTEGRASE
Descriptor: INTEGRASE
Authors:Maignan, S, Guilloteau, J.P, Zhou-Liu, Q, Clement-Mella, C, Mikol, V.
Deposit date:1998-06-22
Release date:1998-11-04
Last modified:2024-05-22
Method:X-RAY DIFFRACTION (2.5 Å)
Cite:Crystal structures of the catalytic domain of HIV-1 integrase free and complexed with its metal cofactor: high level of similarity of the active site with other viral integrases.
J.Mol.Biol., 282, 1998
3EUL
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BU of 3eul by Molmil
Structure of the signal receiver domain of the putative response regulator NarL from Mycobacterium tuberculosis
Descriptor: CHLORIDE ION, POSSIBLE NITRATE/NITRITE RESPONSE TRANSCRIPTIONAL REGULATORY PROTEIN NARL (DNA-binding response regulator, LuxR family)
Authors:Schneider, G, Schnell, R, Agren, D.
Deposit date:2008-10-10
Release date:2008-11-11
Last modified:2023-09-06
Method:X-RAY DIFFRACTION (1.9 Å)
Cite:1.9 A structure of the signal receiver domain of the putative response regulator NarL from Mycobacterium tuberculosis.
Acta Crystallogr.,Sect.F, 64, 2008
1XXC
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BU of 1xxc by Molmil
C-TERMINAL DOMAIN OF ESCHERICHIA COLI ARGININE REPRESSOR
Descriptor: ARGININE REPRESSOR
Authors:Van Duyne, G.D, Ghosh, G, Maas, W.K, Sigler, P.B.
Deposit date:1995-11-03
Release date:1996-03-08
Last modified:2024-02-14
Method:X-RAY DIFFRACTION (2.8 Å)
Cite:Structure of the oligomerization and L-arginine binding domain of the arginine repressor of Escherichia coli.
J.Mol.Biol., 256, 1996
4HCZ
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BU of 4hcz by Molmil
PHF1 Tudor in complex with H3K36me3
Descriptor: H3L-like histone, PHD finger protein 1
Authors:Musselman, C.A, Roy, S, Nunez, J, Kutateladze, T.G.
Deposit date:2012-10-01
Release date:2012-11-14
Last modified:2023-09-20
Method:X-RAY DIFFRACTION (1.85 Å)
Cite:Molecular basis for H3K36me3 recognition by the Tudor domain of PHF1.
Nat.Struct.Mol.Biol., 19, 2012

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