4JL9

Crystal structure of mouse TBK1 bound to BX795

Summary for 4JL9

• Entry DOI: 10.2210/pdb4jl9/pdb
• Descriptor: Serine/threonine-protein kinase TBK1, N-(3-{[5-iodo-4-({3-[(thiophen-2-ylcarbonyl)amino]propyl}amino)pyrimidin-2-yl]amino}phenyl)pyrrolidine-1-carboxamide (2 entities in total)
• Functional Keywords: protein kinase, kinase, transferase-transferase inhibitor complex, transferase/transferase inhibitor
• Biological source: Mus musculus (mouse)
• Total number of polymer chains: 1
• Total formula weight: 76281.84

Authors

Li, P.,Shu, C. (deposition date: 2013-03-12, release date: 2013-06-19, Last modification date: 2024-02-28)

• Primary citation: Shu, C.,Sankaran, B.,Chaton, C.T.,Herr, A.B.,Mishra, A.,Peng, J.,Li, P.; Structural Insights into the Functions of TBK1 in Innate Antimicrobial Immunity.; Structure, 21:1137-1148, 2013; PubMed: 23746807; DOI: 10.1016/j.str.2013.04.025

Experimental method

X-RAY DIFFRACTION (3.0999 Å)